Reconstruction of Full-thickness Lower Eyelid Defects After Basal Cell Carcinoma Excision Using a Modified Hughes Procedure by Francesco Perri, MD, Gianluca Di Monta, MD, Santolo D’Antonio, MD, Pier Paolo Perrella, MD, Anna De Rosa, MD, Vincenzo Rullo, MD, Giorgio Squarcia Neri, MD, Melissa Akuma, MD, Francesco D’Andrea, MD, Stefano Mori, MD

“…The tarsoconjunctival flap from the upper eyelid is an effective method for reconstructing extensive full-thickness lower eyelid defects, providing excellent functional and aesthetic outcomes.…”
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Chlorpyrifos and cypermethrin combination disrupts sonic hedgehog signaling and associated regulatory molecules, leading to congenital eye defects in chick embryos by Shashikant Sharma, Juhi Vaishnav, Pooja Raval, Suresh Balakrishnan

“…Thus, we hypothesized that Ci administration may lead to alteration in Shh expression which subsequently hampers downstream signaling molecules potentially contributing to congenital eye defects. Morphological, anatomical, histological, transcriptional and protein level analyses at various stages (Days 1,2,4 and 10) were carried out to evaluate the hypothesis. …”
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Efficacy of bone graft as monotherapy and in combination with platelet concentrates in grade II furcation defect – A systematic review and meta-analysis by Vinisha Ashok Bajaj, Abhay Pandurang Kolte, Rajashri Abhay Kolte

“…Background: The use of autologous platelet concentrates (PC) in addition to bone graft (BG) in open flap debridement (OFD) has been investigated to improve the efficacy and outcomes of regenerative therapy for furcation defects. This systematic review evaluated efficacy of added benefits of PC to bone grafts in treatment of grade II furcation defects. …”
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Combination of mesenchymal stem cell sheet with poly-caprolactone nanofibrous mat and Gelfoam increased osteogenesis capacity in rat calvarial defect by Behnaz Banimohamad-Shotorbani, Reza Rahbarghazi, Seyedhosein Jarolmasjed, Ahmad Mehdipour, Hajar Shafaei

“…This study aimed to investigate the osteogenic properties of adipose-derived-mesenchymal stem cell (AD-MSC) sheets combined with nanofibrous poly-caprolactone (PCL) mat and Gelfoam in rats with calvarial bone defect. Methods: Calvarial critical-size defects were induced in male rats. …”
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Point Defect Detection and Classification in MoS₂ Scanning Tunneling Microscopy Images: A Deep Learning Approach by Shiru Wu, Guoyang Chen, Si Shen, Jiaxu Yan

“…Precise identification of these defects is essential for understanding defect physics and device performance. …”
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Exposure to non-steroidal anti-inflammatory drugs during pregnancy and the risk of selected birth defects: a prospective cohort study. by Marleen M H J van Gelder, Nel Roeleveld, Hedvig Nordeng

“…Results of human studies on the teratogenic risks of NSAIDs are inconsistent. Therefore, we evaluated the risk of selected birth defects after prenatal exposure to prescribed and over-the-counter NSAIDs.…”
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Advances in Aircraft Skin Defect Detection Using Computer Vision: A Survey and Comparison of YOLOv9 and RT-DETR Performance by Nutchanon Suvittawat, Christian Kurniawan, Jetanat Datephanyawat, Jordan Tay, Zhihao Liu, De Wen Soh, Nuno Antunes Ribeiro

“…Aircraft skin surface defect detection is critical for aviation safety but is currently mostly reliant on manual or visual inspections. …”
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The infection characteristics and autophagy defect of dermal macrophages in STZ‐induced diabetic rats skin wound Staphylococcus aureus infection model by Xiaoying Xie, Rihui Zhong, Ling Luo, Xianghua Lin, Lisi Huang, Songyin Huang, Lijia Ni, Baiji Chen, Rui Shen, Li Yan, Chaohui Duan

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The Effect of Fluid Therapy on the Development of Metabolic Disturbances and ICU Length of Stay in Pediatric Patients Undergoing Surgery for Congenital Heart Defects by N. A. Solovyov, M. M. Rybka, D. A. Dibin, G. E. Gorbunov, S. M. Tsoi, Z. A. Kodzokova, A. A. Goncharov

“…Aim: to compare the effects of restrictive versus liberal fluid therapy on the duration of mechanical ventilation (MV), total intensive care unit (ICU) stay, and the need for inotropic and vasopressor support during the post-perfusion period and the first 24 hours after surgery in young children undergoing surgical correction of congenital heart defects (CHD).Materials and Methods. A prospective, randomized, single-center study included pediatric patients (toddlers) with CHD who were assigned to one of two groups. …”
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DNA mismatch repair defect and intratumor heterogeneous deficiency differently impact immune responses in diffuse large B-cell lymphoma by Zijun Y. Xu-Monette, Cancan Luo, Li Yu, Yong Li, Govind Bhagat, Alexandar Tzankov, Carlo Visco, Xiangshan Fan, Karen Dybkaer, Ali Sakhdari, Nicholas T. Wang, Alyssa F. Yuan, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, Anamarija M. Perry, Wenting Song, Dennis O’Malley, Qingyan Au, Harry Nunns, Heounjeong Go, Michael B. Møller, Benjamin M. Parsons, Santiago Montes-Moreno, Maurilio Ponzoni, Andrés J.M. Ferreri, Aliyah R. Sohani, Jeremy S. Abramson, Bing Xu, Ken H. Young

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Revolutionizing bone regeneration and wound healing: Mechanical stromal vascular fraction and hyaluronic acid in a mouse calvarial defect model by Riccardo Ossanna, Lindsey Alejandra Quintero Sierra, Sara Ghazanfar Tehrani, Vivekanand Jha, Chiara Curatola, Alice Busato, Anita Conti, Giamaica Conti, Nicola Zingaretti, Pier Camillo Parodi, Francesco De Francesco, Michele Riccio, Andrea Sbarbati

“…Through comparative analysis with ED-SVF in a calvarial defect mouse model, we demonstrate the superior efficacy of HT-SVF + ACP in enhancing bone healing, reducing fibrotic tissue, and improving bone matrix maturity.DiscussionThe findings establish the potential of HT-SVF as a cost-effective and efficient method for bone regenerative therapy.…”
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How to adaptively balance ‘classic’ or ‘conservative’ approaches in tooth defect management: a 3D-finite element analysis study by Jiani Xu, Xu Liang, Lili Hu, Chen Sun, Zhipeng Zhang, Jiawei Yang, Jie Wang

“…This study aims to investigate the influence of cavity dimensions on the mechanical performance of resin composites and natural tooth structures using finite element analysis (FEA). By evaluating stress distribution across different cavity configurations, this study seeks to determine the optimal cavity design for various tooth defects, ultimately offering insights into effectively balancing conventional and conservative cavity preparation principles. …”
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Evidence of the correlation between air pollution and different types of birth defects: based on a distribution-lag non-linear model by Wen Sun, Qingqing Dong, Yingying Zhang, Hui Wang, Youqiang Wang, Wenjie Yuan, Leyao Wang, Xianhong Shi, Yuhong Feng, Haiwei Wang, Xiaodan Wang, Yingbin Ren, Lihong Wang, Lijian Lei, Wenxia Song

“…The association between different pollutants and the classification of BDs also varies.DiscussionExposure to pollutants during pregnancy increases the risk of birth defects in newborns, especially SO2, PM10, PM2.5 and O3. …”
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Application of a biologically oriented preparation technique in the restoration of traumatic anterior tooth defects: two cases report and literatures review by LIU Lulu, SHI Jiafan, SUN Mingze, LOU An, GONG Lingling, LI Ming

“…Objective To evaluate the effectiveness of the biologically oriented preparation technique (BOPT) in restoring traumatic tooth defects within the aesthetic zone, serving as a clinical reference. …”
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Iatrogenesis in the Intensive Care by Oksana I. Kosukhina, Ekaterina S. Kachenkova, Gennadiy N. Germanov, Yuliya V. Zbrueva

“…We analyzed findings of the forensic examination and evaluation of medical care of a patient with knife wounds.Results. …”
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IMPROVING THE QUALITY OF WORK ON CULVERT UNDERPASS BOX STRUCTURES USING THE LEAN SIX SIGMA METHOD by Rian Darmawan, Budi Susetyo

“…In addition, the analysis using Lean Six Sigma in Box Culvert work resulted in a DPMO value of 6058 per one million or equivalent to 4.133 sigma with a yield of 99.39%, thus requiring evaluation through the the DMAIC method Define – Measure – Analyze – Improvement – Control) to reduce defects and improve quality. …”
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Hybrid sequence learning with interpretability for multi-class quality prediction in injection molding by Varathorn Punyangarm, Supatchaya Chotayakul

“…This study proposes a novel hybrid deep learning framework that integrates a Transformer encoder with a TabNet classifier to enable interpretable, multi-class defect prediction using time-series part weight data. …”
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Platypnea‐Orthodeoxia Syndrome Post‐Pneumonectomy: A Case of Right‐To‐Left Shunting and Successful PFO Closure by Cristian Castillo‐Rodriguez, Dina Soliman, Michel Juarez, Sherif Roman, John Abdelmalek, Zhaunn Sly, Ankush Lahoti, Victor Test

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A Comparison of Long-Term Right Ventricular Functions in Children with Transcatheter and Surgically Closed Secundum Atrial Septal Defects (ASDs): A Strain Echocardiography Study by Serra Karaca, Doruk Özbingöl, Pelin Karaca Özer, Mustafa Lütfi Yavuz, Türkan Tansel, Kemal Nişli

“…<b>Background/Objectives</b>: Secundum-type atrial septal defect (ASD) is one of the most common congenital heart defects, with an incidence of 5.64 per 10,000 live births worldwide. …”
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Cissus quadrangularis L. hexane extract infused glyoxal cross-linked chitosan-collagen scaffold elicits early osteoinduction by Praseetha R. Nair, P.S. Unnikrishnan, Sachin J. Shenoy, G.S. Sailaja

“…Results: Histopathological evaluation of CHCOHE implanted critical-size calvarial defect in rats indicates the presence of osteoblast cells, neovascularization along with evidence of scaffold degradation by giant cells after 4 weeks. …”
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