Medicarpin, a Natural Pterocarpan, Heals Cortical Bone Defect by Activation of Notch and Wnt Canonical Signaling Pathways. by Manisha Dixit, Ashutosh Raghuvanshi, Chandra Prakash Gupta, Jyoti Kureel, Mohd Nizam Mansoori, Priyanka Shukla, Aijaz A John, Kavita Singh, Dipak Purohit, Pallavi Awasthi, Divya Singh, Atul Goel

“…We evaluated the bone regeneration and healing effect of Medicarpin (med) in cortical bone defect model that heals by intramembranous ossification. …”
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Vascularized fibular epiphyseal transfer for biological reconstruction of bone defects following resection in children with proximal humeral sarcoma by Jun Li, Xianzhe Tang, Lu Wang, Tang Liu

“…Abstract Background The functional reconstruction of bone defects following resection of proximal humerus tumors in children poses a significant challenge. …”
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A pilot study on the incorporation of adipose-derived stem cells into bone cements to enhance bone defect regeneration by Julia Lucas-Aparicio, Jatsue Cabrejos-Azama, Jesús Torres, Carmen Rueda, Mohammad-H. Alkhraisat, Luis Blanco-Jerez, Enrique López-Cabarcos

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Reconstruction of skin and soft-tissue defects of the foot: Challenges, techniques, and results. A retrospective-prospective observational study by Kiran Petkar, Prabhu T

“…Results: A total of 28 cases of foot defects were studied. The most common causes were trauma and diabetic foot. …”
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Lateral Approach for Regenerative Treatment of Intrabony Defects Associated With an Edentulous Alveolar Ridge: A Prospective Case Series by Filip Hromčík, Adéla Halusková, Lydie Izakovičová Hollá

“…ABSTRACT Objectives This case series evaluated the clinical efficacy of the novel “lateral approach” combined with an enamel matrix derivative (EMD) and bone grafting in the regenerative surgical treatment of intrabony defects associated with an edentulous ridge. …”
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Preventing the Development of Visual Defects with Early Treatment in Cases Diagnosed with Periocular Hemangioma: A Single Center Experience by Aytül Temuroğlu, Betül Berrin Sevinir

“…If located around the orbit, it may cause amblyopia and permanent vision defects. Therefore, early treatment is very important. …”
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Three-Dimensional Assessment of the Biological Periacetabular Defect Reconstruction in an Ovine Animal Model: A µ-CT Analysis by Frank Sebastian Fröschen, Thomas Martin Randau, El-Mustapha Haddouti, Jacques Dominik Müller-Broich, Frank Alexander Schildberg, Werner Götz, Dominik John, Susanne Reimann, Dieter Christian Wirtz, Sascha Gravius

“…The increasing number of acetabular revision total hip arthroplasties requires the evaluation of alternative materials in addition to established standards using a defined animal experimental defect that replicates the human acetabular revision situation as closely as possible. …”
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Lost in translation: the lack of agreement between surgeons and scientists regarding biomaterials research and innovation for treating bone defects by Markus Laubach, Stephen Whyte, Ho Fai Chan, Tina Frankenbach-Désor, Susanne Mayer-Wagner, Frank Hildebrand, Boris M. Holzapfel, Ulrich Kneser, Uwe Dulleck, Dietmar W. Hutmacher

“…This research aimed to unravel disparities in the knowledge and evaluation of current and future bone defect treatments between surgeons and biomaterial scientists. …”
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Imaging observation of allogeneic bone and bone-induced calcium phosphate biomaterials as supplements in the treatment of infectious bone defects by Keye Li, Shan Yu, Daqiang Lin, Xu Zhang, Yuxiang Liang, Dong He, Qiang Guo, Junyu Tao, Yu Zhong, Zhigang Lang

“…Both materials were applied for bone defect reconstruction during surgery. Digital radiography (DR) imaging examinations were performed at three timepoints (postoperative, 3 months postoperative, 6 months postoperative) to evaluate osseous regeneration. …”
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Analysis of the therapeutic effect of right mid-axillary approach in the surgical treatment of ASD and VSD in children by Fuqiang Li, Tian Cheng, Mingliang Yan, Tao Li, Tianchen Zhang, Yaoxuan Huang, Jian Tang

“…Abstract Background To compare the therapeutic effects of right vertical infra-axillary thoracotomy (RVIAT) and Standard Median Sternotomy (SMS) in the repair of atrial septal defect (ASD) and ventricular septal defect (VSD), and to evaluate the safety and effectiveness of right subaxillary incision technique in the surgical treatment of common congenital heart disease (CHD) in children. …”
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Masquelet’s induced membrane technique for the reconstruction of post-traumatic, open-grade distal femur fracture with bone defect by Rameez A Musa, Darshan U Shah, Vipul R Makwana, Arvind K Hadiya, Parth K Shah, Neel M Bhavsar

“…The aim of this study is to evaluate the outcome of induced membrane technique in the reconstruction of open distal femur fracture with bone defect. …”
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Nonsurgical Management of Furcation Defects Using Cervical Sealing With Calcium–Silicate Cements: A Clinical Case Series by Saeed Asgary

“…This case series investigates the use of calcium–silicate biomaterials, specifically calcium-enriched mixture (CEM) cement, as cervical sealants in the nonsurgical management of furcation defects with endodontic origin, evaluating their regenerative potential and clinical applicability. …”
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Factors Related to a Right-Left Difference in Visual Field Defect in the Eyes with Untreated Normal Tension Glaucoma by Haruka Moroi, Ayako Anraku, Kyoko Ishida, Goji Tomita

“…To investigate factors related to a right-left difference in visual field defect in untreated normal tension glaucoma (NTG). …”
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Preparation of composite calcium phosphate cement scaffold loaded with Hedysarum polysaccharides and its efficacy in repairing bone defects by Lianggong Zhao, Bo Wang, Shilan Feng, Huifang Wu

“…The success of CPS + HPS in repairing bone defects was evaluated by using a rabbit femur implantation experiment. …”
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Automatic Detection and Classification of Natural Weld Defects Using Alternating Magneto-Optical Imaging and ResNet50 by Yanfeng Li, Pengyu Gao, Yongbiao Luo, Xianghan Luo, Chunmei Xu, Jiecheng Chen, Yanxi Zhang, Genxiang Lin, Wei Xu

“…To further enhance the classification accuracy of natural weld defects, a convolutional neural network (CNN) classification model and a ResNet50 classification model for MO images of natural weld defects are established, and the model parameters are evaluated and optimized. …”
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Bone repair in defects filled with AH Plus sealer and different concentrations of MTA: a study in rat tibiae by Jessica Emanuella Rocha Paz, Priscila Oliveira Costa, Albert Alexandre Costa Souza, Ingrid Macedo de Oliveira, Lucas Fernandes Falcão, Carlos Alberto Monteiro Falcão, Maria Ângela Area Leão Ferraz, Lucielma Salmito Soares Pinto

“…ObjectivesThis study aimed to evaluate the effects on bone repair of different concentrations of mineral trioxide aggregate (MTA) added to AH Plus.Materials and MethodsBone tissue reactions were evaluated in 30 rats (Rattus norvegicus) after 7 and 30 days. …”
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Revision total hip arthroplasty with medial wall defect using bone graft with or without porous metal restrictor by Min Uk Do, Sang Woo Kang, Sang-Min Lee, Jae Jin Kim, Kuen Tak Suh, Won Chul Shin

“…We aimed to evaluate whether there were differences in outcomes of revision THA with medial wall defects depending on the use of TM augmentation. …”
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Three‐Dimensional Printed Prosthesis Reconstructs Bilateral Type III Pelvic Defect After Malignant Tumors Resection by Xuanhong He, Yi Luo, Chang Zou, Minxun Lu, Yuqi Zhang, Zhuangzhuang Li, Guy Romeo Kenmegne, Yong Zhou, Li Min, Chongqi Tu

“…Three‐dimensional (3D)‐printed prosthesis was designed to reconstruct the unilateral Type III pelvic defect and had favorable clinical outcomes. However, the reconstruction method for bilateral Type III pelvic defect was few reported. …”
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Ilizarov method combined with accordion technique for treating long bone defects in the lower limbs: a systematic review by Zhiqiang Ren, Jinghong Yang, Zi Wang, Lujun Jiang, Lian Tang, Jiyuan Yan, Juncai Liu, Yanshi Liu, Zhong Li

“…Results Drawing from eight studies involving 80 patients with bone defects treated through the Ilizarov method combined with the accordion technique, this systematic review evaluated the method’s impact on bone regeneration. …”
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Research on corrosion defect identification and risk assessment of well control equipment based on a machine learning algorithm by He Zhang, Jiangna Cao, Haibo Liang, Gang Cheng

“…In recent years, the risk assessment of well control equipment has faced some problems, such as shallow defect detection depth, large identification error of corrosion defect type, inaccurate equipment corrosion assessment, and so on. …”
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