Identifying the effects of an upgraded ‘fever clinic’ on COVID-19 control and the workload of emergency department: retrospective study in a tertiary hospital in China by Yan Li, Yi Li, Fan Li, Xuezhong Yu, Jun Xu, Jiangshan Wang, Liang Zong, Jinghong Zhang, Han Sun, Joseph Harold Walline, Pengxia Sun, Shengyong Xu, Chunting Wang, Jihai Liu, Huadong Zhu

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Efficacy of Yijinjing for Soft Tissue Improvement in Patients with Non-specific Chronic Neck Pain: Study Protocol for a Multicenter Randomized Controlled Trial by Fei Yao, Xiang Chen, Fangfang Xie, Min Fang, Hongyu Yue, Hanyu Zou, Zonglin Wen

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Effect of music listening on delirium after hip fracture operations (MLDHFO) in a regional hospital in Taiwan: a randomised controlled trial protocol by Ling Wang, Lin-Yu Chao, Chun-Chih Lin, Hsing-Ju Lu, Jiun-Liang Chen, Han-Chang Ku

“…The trial will be carried out following the Declaration of Helsinki principles and Good Clinical Practice guidelines. …”
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Design of a phase III, double-blind, randomised, placebo-controlled trial of BI 1015550 in patients with idiopathic pulmonary fibrosis (FIBRONEER-IPF) by Toby M Maher, Michael Kreuter, Vincent Cottin, Susanne Stowasser, Marlies S Wijsenbeek, Yi Liu, Fernando J Martinez, Luca Richeldi, Arata Azuma, Justin M Oldham, Claudia Valenzuela, Maud Gordat, Donald F Zoz

“…Methods and analysis In this placebo-controlled, double-blind, phase III trial, patients are being randomised in a 1:1:1 ratio to receive 9 mg or 18 mg of BI 1015550 or placebo two times per day over at least 52 weeks, stratified by use of background antifibrotics (nintedanib/pirfenidone vs neither). …”
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Rationale and Design of a Randomized Controlled Trial on Intensive Management of Blood PRESSure and Cholesterol in Elderly Chinese with Hypertension and Atrial FibrillatION (IMPRES... by Wei Zhang, Yi Chen, Qifang Huang, Ji-Guang Wang, Tianyu Xu, Xiaoxia Fu.

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Randomised sham-controlled double-blind trial evaluating remote ischaemic preconditioning in solid organ transplantation: a study protocol for the RIPTRANS trial by Anni Pulkkinen, Ilkka Helanterä, Aki Uutela, Karl Lemström, Arie Passov, Simo Syrjälä, Fredrik Åberg, Heikki Mäkisalo, Arno Nordin, Marko Lempinen, Minna Bäcklund, Markus Skrifvars, Teemu Luostarinen, Janne Reitala, Maarit Lång, Ilona Leppänen, Jaakko Långsjö, Juha Grönlund, Pekka Loisa, Björn Jäschke

“…The intervention is done two times: first right after the declaration of brain death and second immediately before transferring the donor to the operating theatre. …”
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Habitat analysis of iron deposition in the basal ganglia for diagnosing cognitive impairment in chronic kidney disease: evidence from a case-control study by Hao Wang, Yu Qi, Xu Liu, Li-Jun Song, Wen-Bo Yang, Ming-An Li, Xiao-Yan Bai, Mao-Sheng Xu, Hao-Nan Zhu, Si-Qing Cai, Yi Wang, Zheng-Han Yang, Yuan-Zhe Li, Zhen-Chang Wang, Yi-Fan Guo

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Design of a phase III, double-blind, randomised, placebo-controlled trial of BI 1015550 in patients with progressive pulmonary fibrosis (FIBRONEER-ILD) by Toby M Maher, Michael Kreuter, Vincent Cottin, Daniel Wachtlin, Anna-Maria Hoffmann-Vold, Marlies S Wijsenbeek, Fernando J Martinez, Shervin Assassi, Luca Richeldi, Arata Azuma, Justin M Oldham, Claudia Valenzuela, Carl Coeck, Christina Schlecker, Florian Voss

“…Following positive results in a phase II study in IPF, this phase III study will investigate the efficacy and safety of BI 1015550 in patients with PPF (FIBRONEER-ILD).Methods and analysis In this phase III, double-blind, placebo-controlled trial, patients are being randomised 1:1:1 to receive BI 1015550 (9 mg or 18 mg) or placebo twice daily over at least 52 weeks, stratified by background nintedanib use. …”
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Determinants of Acute Malnutrition among Under-Five Children in Governmental Health Facilities in Sodo Town, Southern Ethiopia: Unmatched Case-Control Study by Zenebe Jebero, Fikre Moga, Bereket Gebremichael, Tewodros Tesfaye

“…A logistic regression model was used to identify the determinants of acute malnutrition, and statistical significance was declared at P<0.05. Result. A total of 133 cases and 266 controls were included in the study making a response rate of 97.8%. …”
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Sepsis Risk Factors in Neonatal Intensive Care Units of Public Hospitals in Southeast Ethiopia, 2020: A Retrospective Unmatched Case-Control Study by Gemechu Ganfure, Bikila Lencha

“…An adjusted odds ratio with a 95% confidence interval was used to determine the degree of association, and statistical significance was declared at a p value of < 0.05. Results. In this study, 97 cases and 194 controls were included. …”
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Determinants of compliance with iron-folic acid supplementation among pregnant mothers in Bule Hora district, Southern Ethiopia: unmatched case-control study by Reta Tesfa Merga, Mahlet Birhane, Midhagsaa Dhinsa, Biranu Muleta, Jibril Jemal, Moges Mareg Belay

“…Methods A health facility -based, unmatched case-control study was conducted in Bule Hora district from April 2024 to June 2024, via a pretested interviewer-administered questionnaire. …”
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Effectiveness of shared decision-making for glycaemic control among type 2 diabetes mellitus adult patients: A systematic review and meta-analysis. by Edosa Tesfaye Geta, Dufera Rikitu Terefa, Wase Benti Hailu, Wolkite Olani, Emiru Merdassa, Markos Dessalegn, Miesa Gelchu, Dereje Chala Diriba

“…Finally, the statistically significant MD of HbA1c% between the intervention groups engaged in SDM and control groups received usual care was declared at P ˂0.05, using a 95% confidence interval (CI).…”
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The effectiveness of the educational package of happiness skills based on Islamic approach and comparison with Fordyce's happiness package on happiness, life satisfaction and anger... by Tayebe Vahdani Khorram, Fatemeh Fayyaz, j avad Eynypour

“…The purpose of the present study was to evaluate of the effectiveness of the educational package of happiness skills based on the Islamic approach for happiness, life satisfaction and anger control in mothers and compared the results with Fordyce package. …”
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Intensive and standard group-based treatment for persons with social communication difficulties after an acquired brain injury: study protocol for a randomised controlled trial by Jan Stubberud, Silje Merethe Hansen, Marianne Hjertstedt, Melanie Kirmess

“…The trial will be conducted in accordance with the Declaration of Helsinki and reported in accordance with the Consolidated Standards of Reporting Trials 2010 statement and Standard Protocol Items: Recommendations for Interventional Trials recommendations.Trial registration number NCT03636399.…”
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Effectiveness of Fewer Falls, an online group-based self-management fall prevention programme for people with multiple sclerosis: protocol of a randomised controlled trial by Maria Flink, Charlotte Ytterberg, Kristina Gottberg, Marie Kierkegaard, Susanna Tuvemo Johnson, Elizabeth Walker Peterson, Ulrika Meijer, Johanna Bylinder

“…The RCT will adhere to the Declaration of Helsinki. Written consent to participate will be obtained from all participants. …”
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Effects of intravenous propofol combined with opioids on euphoria in patients undergoing painless gastrointestinal endoscopy: protocol for a randomized double-blind placebo-control... by Youjia Yu, Qingfang Ma, Fengxia Du, Xiang Zhang, Chunyan Shao, Yan Li, Chuntao Ma

“…All participants will provide written informed consent, and the study will adhere to the principles of the Declaration of Helsinki. The findings will be published in a peer-reviewed journal. …”
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Impact of an educational physiotherapy-yoga intervention on perceived stress in women treated with brachytherapy for cervical cancer: a randomised controlled mixed study protocol (... by Marta Jarlier, Estelle Laboureur, Kerstin Faravel, Laetitia Meignant, Maguy Del Rio, Sylvain Demontoy, Mailys De-Meric-de-Bellefon, Marie Cantaloube, Estelle Guerdoux

“…Eighty patients are planned to be randomised (1:1) into a control arm (standard care) or an intervention arm. …”
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Guided self-determination intervention versus attention control for people with type 2 diabetes in outpatient clinics: a protocol for a randomised clinical trial by Christian Gluud, Jane Lindschou, Thordis Thomsen, Janus C Jakobsen, Vibeke Zoffmann, Anne Sophie Mathiesen, Tine Bruhn Skytte, Bodil Rasmussen, Emilie Marqvorsen, Mette Rothmann

“…We describe the protocol for a pragmatic randomised, dual-centre, parallel-group, superiority clinical trial testing a GSD intervention versus an attention control for people with type 2 diabetes in outpatient clinics. …”
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Effect of testosterone treatment during puberty in boys with Klinefelter syndrome (The TIPY Study): protocol for a nationwide randomised, double-blinded, placebo-controlled study by Gary Butler, Anders Juul, Judith L Ross, Jørgen Holm Petersen, Kurt Kristensen, Ann-Margrethe Rønholt Christensen, Ida Dyhr Caspersen, Andrés Felipe Østergaard Fritzbøger, Niels Birkebæk, Anders Jørgen Schou, Shanlee Davis, Sophie van Rijn, Lise Aksglaede

“…Neuropsychological assessment will be conducted at baseline and after 24 months of treatment.Ethics and dissemination The study will be conducted in accordance with the Helsinki Declaration. The study has been approved by the Danish National Medical Research Ethics Committee and the Danish Medicines Agency (Clinical trials information system number 2023-505854-16-00). …”
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Non-ischaemic preservation of the donor heart in heart transplantation: protocol design and rationale for a randomised, controlled, multicentre clinical trial across eight European... by Göran Dellgren, Filip Rega, Janne Brouckaert, Andreas Wallinder

“…This study will be conducted in accordance with current local regulations and international applicable regulatory requirements according to the principles of the Declaration of Helsinki and ISO14155:2020. Main primary and secondary outcomes will be published on modified intention-to-treat population and per-protocol population.Trial registration number NCT03991923.…”
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