A systematic approach to capacity strengthening of laboratory systems for control of neglected tropical diseases in Ghana, Kenya, Malawi and Sri Lanka. by Janet Njelesani, Russell Dacombe, Tanith Palmer, Helen Smith, Benjamin Koudou, Moses Bockarie, Imelda Bates

“…<h4>Background</h4>The lack of capacity in laboratory systems is a major barrier to achieving the aims of the London Declaration (2012) on neglected tropical diseases (NTDs). …”
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Dydrogesterone for preventing endometrial polyp recurrence after transcervical resection of polyps: protocol for a multicentre randomised controlled trial in China by Dewen Yan, Yao He, Ting Wang, Yuan Ge, Linhua Qian, Lingfang Ye, Xiufeng Huang

“…The intervention group will receive oral dydrogesterone for three menstrual cycles, whereas the control group will receive no hormonal treatment. …”
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Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial by Xue Gao, Lu Liu, Mei-Rong Pan, Hai-Mei Li, Yu-Feng Wang, Xue-Ying Liu, Zhong-Fang Fu, Qiujin Qian

“…Participants will be assessed at baseline (T1), week 4 (T2), week 8 (T3), post-treatment (T4) and 3 month follow-up (T5).Discussion This protocol outlines the first randomised controlled trial investigating the efficacy of the UP-A among Chinese adolescents with emotional disorders. …”
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Effect of music on clinical outcome after hip fracture operations (MCHOPIN): study protocol of a multicentre randomised controlled trial by Detlef van der Velde, Marten J Poley, Esther M M van Lieshout, Michael H J Verhofstad, Johan Haumann, Johannes Jeekel, Robert Haverlag, Victor X Fu, Leonie J P Slegers

“…The trial will be carried out following the Declaration of Helsinki principles, Good Clinical Practice guidelines and Dutch Medical Research Involving Human Subjects Act. …”
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Association of nociceptive, neurocognitive, psychological and genetic profile on conditioned pain modulation in women with migraine: protocol for a case–control study by Lars Arendt-Nielsen, Margarita Cigarán-Méndez, César Fernández De las Peñas, Silvia Ambite-Quesada, Ana I de-la-Llave-Rincón, Gustavo Plaza-Manzano, Cristina Gómez-Calero, Francisco G Fernández-Palacios, Juan C Pacho-Hernández, Angela Tejera-Alonso, Juan A Valera-Calero, Beatriz Alvarez-Mariño, Carlos Ordás-Bandera

“…The aim of the current study will be to evaluate the association between sensitisation, psychological/emotional, neurocognitive and genetic profile on conditioned pain modulation (CPM) in women with migraine from a multidisciplinary perspective.Methods and analysis A cross-sectional observational case–control study including 90 women with chronic migraine, 90 women with episodic migraine and 90 women without migraine (as controls) will be conducted. …”
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Phantom motor execution as a treatment for phantom limb pain: protocol of an international, double-blind, randomised controlled clinical trial by Brian E McGuire, Lina Bunketorp-Käll, Eva Lendaro, Liselotte Hermansson, Helena Burger, Corry K Van der Sluis, Monika Pilch, Katarzyna Kulbacka-Ortiz, Ingrid Rignér, Anita Stockselius, Lena Gudmundson, Cathrine Widehammar, Wendy Hill, Sybille Geers, Max Ortiz-Catalan

“…Introduction Phantom limb pain (PLP) is a chronic condition that can greatly diminish quality of life. Control over the phantom limb and exercise of such control have been hypothesised to reverse maladaptive brain changes correlated to PLP. …”
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Evaluation of a health systems strengthening intervention to improve Ebola Virus Disease infection prevention and control in the Democratic Republic of the Congo by Kevin Ousman, Meaghan Thumath, Gillian McKay, David Niyukuri, Didier Mwesha Ombeni, Landry Kabego, Berthe Banzua, Samuel Mangala, Robert Tatabod, Patrick Mirindi N., Ambrose Talisuna, Bienvenu Houndjo, Mory Kieta, April Baller

“…# Background The Democratic Republic of Congo declared their tenth outbreak of Ebola in North Kivu in 2018, which was the second-largest in the world and took place in an active conflict zone. …”
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Effectiveness of music with auditory beat stimulation in reducing state anxiety in Canadian students with trait anxiety: protocol for a randomised controlled trial by Rhiannon Ueberholz, Harley Glassman, Adiel Mallik, Frank A Russo

“…It is hypothesised that relative to a pink noise control, listening to music with ABS will lower self-reported anxiety, reduce salivary cortisol, increase heart rate variability, increase theta and alpha-band electroencephalography (EEG) power and decrease beta and gamma-band EEG power.Methods and analysis Fifty Canadian undergraduate students who self-report experiencing anxiety will be recruited for this two-arm randomised controlled trial. …”
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Tofacitinib in early active axial spondyloarthritis: protocol of a randomized double-blind, placebo-controlled, multicenter phase IV study, FASTLANE by Valeria Rios Rodriguez, Lidia Sánchez-Riera, Hildrun Haibel, Caroline Höppner, Murat Torgutalp, Fabian Proft, Judith Rademacher, Elke Binder, Annette Diehl, Ivana Vranic, Yuxi Zhao, Rajiv Mundayat, Arne Yndestad, Denis Poddubnyy

“…Ethics: The study will be performed according to the ethical principles of the Declaration of Helsinki and will be approved by independent ethics committees of each center. …”
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Transcranial direct current stimulation combined with physical exercise in rotator cuff tendinopathy: a protocol for a blinded randomised controlled trial by César Augusto Medeiros Silva, Clécio Gabriel de Souza, Vinicius Batista Lima, Hannely Beatriz Menezes Cosme, Romário Nóbrega Santos Fonseca, Fuad Ahmad Hazime, Rodrigo Scattone da Silva, Rodrigo Pegado de Abreu Freitas

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Efficacy of periodontal soft tissue augmentation prior to orthodontic treatment on preventing gingival recession: study protocol for a randomised controlled trial by Jing Chen, Qiang Li, Wei Zhang, Fan Zhang, Jiashu Lv, Yuhui Wang, Yichen Xu, Yichen Pan

“…The study was conducted in accordance with the Declaration of Helsinki, the Clinical Trials Act and other current legal regulations in China. …”
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Comparing the accuracy of positive and negative indocyanine green staining in guiding laparoscopic anatomical liver resection: protocol for a randomised controlled trial by Malek Abdallah Muflih Alomari, Taiga Wakabayashi, Marco Colella, Yoshiki Fujiyama, Ebaa Ababneh, Go Wakabayashi, Kohei Mishima

“…There are two methods of ICG staining (positive and negative), and the superiority of either approach has not been determined to date.Methods and analysis This is a prospective randomised controlled superiority clinical trial performed in a single centre tertiary hospital in Japan. …”
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Transcutaneous auricular vagus nerve stimulation prevents postoperative delirium in elderly patients (VNSTAR): protocol for a multicentre, randomised controlled trial by Anxin Wang, Bo Wang, Ruquan Han, Fa Liang, Youxuan Wu, Minyu Jian, Xinyan Wang, Haiyang Liu, Xuan Hou, Kangda Zhang, Tianyuan Wang

“…To date, no large prospective, randomised controlled studies have explored the effects of vagus nerve stimulation on POD.Method and analysis This study is a multicentre, double-blind, parallel, randomised controlled trial. …”
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Cognitive-bias modification intervention to improve physical activity in patients following a rehabilitation programme: protocol for the randomised controlled IMPACT trial by Stéphane Cullati, Axel Finckh, Delphine S Courvoisier, Boris Cheval, Matthieu P Boisgontier, Reinout W Wiers, Silvio Maltagliati, Layan Fessler, David Sander, Malte Friese, Christophe Luthy

“…The Improving Physical Activity (IMPACT) trial proposes to fill this knowledge gap by investigating the effect of a cognitive-bias modification intervention aiming to modify the automatic approach towards exercise-related stimuli on PA among patients.Methods and analysis The IMPACT trial is a single-centre, placebo (sham controlled), triple-blinded, phase 3 randomised controlled trial that will recruit 308 patients enrolled in a rehabilitation programme in the Division of General Medical Rehabilitation at the University Hospital of Geneva (Switzerland) and intends to follow up them for up to 1 year after intervention. …”
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Electroacupuncture Prevent and Treat Perioperative Cognitive Impairment in Elderly Patients Undergoing Hip Surgery: A Protocol for a Randomized Controlled Trial by Fang Q, Xie J, Zheng S, Hou Y, Wu M, Chen Y, Yang Y, Wang G, Li J

“…However, the mechanism of electroacupuncture treatment for PND is comparatively unexplored.Methods/Design: This is a single-center clinical, prospective randomized controlled clinical trial protocol. 180 patients will be randomly divided into the treatment group and the control group in a ratio of 1:1. …”
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Peut-on considerer qu’un nouveau droit du maintien dans l’emploi est en cours d’élaboration ? by Hervé Gosselin

“…The employer’s obligations regarding the reclassification of a salaried employee who cannot remain at his job, is subject to two different legal rules, depending on whether the employee is declared “able,” subject to adaptation of his workstation, or "disabled" by the occupational physician. …”
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Determinants of weight gain among adult tuberculosis patients on dots during intensive phase in Wonago Ethiopia, unmatched case control study by Licky Eyob, Helen Ali, Yohanness Adisu, Adane Tesfaye

“…A total of 258 tuberculosis patients were included (86 cases and 172 controls). Both Case and Control were selected consecutively with proportional allocation and used all public health facilities in the Wonago District. …”
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Comparison of complications and recovery after laparoscopic and abdominal hysterectomy for benign disease: the LAparoscopic Versus Abdominal hysterectomy (LAVA) randomised controll... by Laura Jones, Rebecca Woolley, Paul Smith, Lee Middleton, Ertan Saridogan, Lina Antoun, T Justin Clark, William McKinnon, Kevin Cooper, Sheriden Bevan, Jayne Fullard, Monique Morgan, Kamila Ziomek, Zeyah Sairally

“…Objective To compare recovery after laparoscopic hysterectomy (LH) and abdominal hysterectomy (AH).Design A parallel, open, non-inferiority, multicentre, randomised controlled, expertise-based surgery trial.Setting 10 NHS (National Health Service) hospitals within the UK.Participants Women undergoing hysterectomy for a benign gynaecological condition.Interventions Consenting women of 18–55 years were randomised to LH or AH using a secure internet facility by a surgeon with self-declared expertise. …”
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Reproducibility and Transparency Practices in a Sample of Nutrition- or Diet-Related Randomised Controlled Trial Publications: A Cross-Sectional Meta-Research by Michael Schlussel, Flavia Moraes, Simone Bernardes, Solange Durão

“…Background and objectives: Journal articles describing randomised controlled trials (RCTs) are not optimally reported, often missing crucial details that ensure transparency and reproducibility. …”
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Unveiling the pathways: identifying the multifaceted determinants of low birth weight among neonates in low-income countries: a case-control study by Dube Jara, Angefa Ayele, Dukele Boneya, Jitu Beka, Miesa Gelchu, Alo Edin

“…Therefore, this study aimed to determine the common determinants of low birth weight among neonates born at public hospitals in Southern Ethiopia.Methods An unmatched case–control study was conducted among 258 neonates (86 cases and 172 controls) born at public hospitals between 15 April and 25 May 2022. …”
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