VALIDATION OF LONG-TERM HANDLING AND STORAGE CONDITIONS FOR HEMATOPOIETIC STEM CELL PRODUCTS FOR AUTOLOGOUS TRANSPLANTS by Ahmed Al Bahrani

“…This study was conducted under the principles of the Declaration of Helsinki. Following PBHSC collection, samples for quality testing were obtained from the PBHSC bags as a control. …”
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Pharmacokinetics and pharmacodynamics of ciprofol after continuous infusion in elderly patients by Xiaowen Guo, Yang Qiao, Sijie Yin, Fengqin Luo, Lingmei Yi, Jiajia Chen, Man Lu

“…Method In this randomized, controlled study, thirty elderly patients (62–78 years old) undergoing elective gastrointestinal tumor resection were treated with propofol (N = 15) or ciprofol (N = 15) as sedatives during anesthesia. …”
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STatin TReatment for COVID-19 to Optimise NeuroloGical recovERy (STRONGER): study protocol for a randomised, open label clinical trial in patients with persistent neurological symp... by Sharon L Naismith, Mark Woodward, Ruth Peters, Xia Wang, Craig S Anderson, Sophia Zoungas, Cheryl Carcel, Paula Muñoz-Venturelli, Karin Leder, Ian H Harding, Meng Law, Julian Elliott, Owen Hutchings, Carlos Delfino, Xiaolei Lin, Nirupama Wijesuriya, Ximena Stecher

“…A total of 410 participants with long covid neurological symptoms were planned to be randomly assigned to either the intervention group to receive 40 mg atorvastatin for 12 months or to a control group of no treatment, on top of usual care.Ethics and dissemination This study protocol was designed, implemented and reported, in accordance with the International Conference on Harmonisation guidelines for Good Clinical Practice, the National Health and Medical Research Council of Australia, the National Statement on Ethical Conduct in Human Research and with the ethical principles laid down in the World Medical Association Declaration of Helsinki. …”
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Effects of high-intensity interval and moderate-intensity continuous training on ambulatory blood pressure and cardiovascular outcomes in older adults with hypertension (HEXA Study... by Francisco Dalton-Alves, Maria Beatriz F Araújo, Bruno Erick B Lucena, Gabriel C Souto, Daniele Samara D Lopes, Maria Isabel S Lucena, Raíssa de Melo Silva, Ludmila L P Cabral, Yuri A Freire, Fabíola L Golveia, Telma Maria Araújo Lemos, Rodrigo A V Browne, Eduardo Caldas Costa

“…The trial is conducted with blinded outcome assessors and statistical analysts. 66 inactive older adults with hypertension aged 60–80 years without a history of major adverse cardiovascular events will be randomly assigned to one of the following groups: (1) HIIT (3 months; 3× week); (2) MICT (3 months; 3× week); (3) health education programme (control; 3 months; 1× week). Exercise training sessions involve rating of perceived exertion-based outdoor moderate walking, brisk walking and/or jogging. …”
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Sex hormone-dependent host-microbiome interactions and cardiovascular risk (XCVD): design of a longitudinal multi-omics cohort study by Rima Chakaroun, Dorte Glintborg, Haiko Schlögl, Nico Steckhan, Lajos Marko, Marianne Andersen, Kristina Franz, Anja Mähler, Sascha Heinitz, Julia Sacher, Ralf Dechend, Noah Adams, Martin Viehweger, Lina Samira Bahr, Sofia Kirke Forslund-Startceva

“…Participants will complete online questionnaires on physical activity, mental health, stress, quality of life, fatigue, sleep, pain, and gender dysphoria, tracking medication use and diet to control for confounders. Statistical analyses will integrate phenomic, lifestyle, and multi-omic data to model health effects, testing gut microbiome mediation of CVD risk as the endocrine environment shifts between that typical for cisgender men to women and vice versa.Ethics and dissemination The study adheres to Good Clinical Practice and the Declaration of Helsinki. …”
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Features of Glucose Homeostasis and Blood Lipid Spectrum in Patients with Nonalcoholic Fatty Liver Dis­ ease Depending on the Obesity Degree by Korniichuk I., Khukhlina O., Vivsyannuk V., Yatskevych O., Kovalska І.

“…Groups of patients with NASH, in turn, were divided into clusters: 2a and 3a ­ patients with NASH and the increased AST activity in blood up to 3 times higher than norm (20 people), 2b and 3b – patients, AST activity in which exceeded the upper limit of norm more than in 3 times (p < 0.05). The control group consisted of 20 practically healthy persons (PHPs) of the corresponding age and gender. …”
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Comparative effectiveness and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate in patients with HBV-associated decompensated cirrhosis: insights from a retrospe... by Lu Chen, Hui-Fang Zhang, Yi-Jing Cai, Lei Zhang, Chao Cai, Ming-Qin Lu, Yue-Ying Zhu

“…Given the severity of decompensated cirrhosis, selecting the most appropriate first-line antiviral medication is crucial for optimizing treatment outcomes and providing the best possible disease control. This retrospective real-world study aimed to evaluate the comparative effectiveness and safety profiles of tenofovir alafenamide (TAF) versus tenofovir disoproxil fumarate (TDF) in patients with hepatitis B virus (HBV)-related decompensated cirrhosis. …”
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Quality management system in vocational education of the Republic of Belarus: Improvement strategy by V. N. Golubovsky

“…The contradiction between the declaration of goals in the field of quality of education in strategic programme documents and the attempt to achieve them exclusively through the control function determines the need to improve the quality management system of vocational education in the Republic of Belarus in modern conditions.Aim. …”
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Better public housing management in Ghana by Samson Aziabah

“…All signatory countries to the Universal Declaration on Human Rights are enjoined to take steps to provide decent and adequate housing to their people. …”
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PERINATAL ASPECTS OF DELIVERY OF WOMEN WITH OBESITY AND GESTATIONAL DIABETES by О. Железняков, В. Лазуренко, І. Васильєва, Т. Фролова, Р. Сафонов, О. Лященко, О. Овчаренко

“…According to the results of ultrasound cervicometry in pregnant women in the control group, the average length of the cervix was 18.7±2.3 mm, which is considered promising for spontaneous delivery. …”
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Combined use of a broad-panel respiratory multiplex PCR and procalcitonin to reduce duration of antibiotics exposure in patients with severe community-acquired pneumonia (MULTI-CAP... by Isabelle Durand-Zaleski, Eric Maury, Bruno Megarbane, Tabassome Simon, Jean-François Timsit, Jean Dellamonica, Saad Nseir, Alexandra Rousseau, Laurence Bérard, Kada Klouche, Yacine Tandjaoui-Lambiotte, Jean Reignier, Laurent Argaud, Muriel Fartoukh, Keyvan Razazi, Laurence Armand-Lefevre, Bertrand Souweine, Guillaume Voiriot, Charlotte Verdet, Juliette Patrier, Jean-Christophe Richard, Carole Schwebel, Jean-Christophe Navellou, Pierre-Francois Dequin, Pierre-Edouard Bollaert, Marc Gainnier, Julien Bohe

“…Subjects are randomised (1:1 ratio) to either the intervention arm (experimental strategy) or the control arm (usual strategy). In the intervention arm, the microbiological diagnosis combines a respiratory multiplex PCR (mPCR) and conventional microbiological investigations. …”
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PLANNING PHASE 2 MULTICENTER RANDOMIZED TRIAL OF NEOADJUVANT CHEMO-RADIOTHERAPY FOLLOWED BY D2 GASTRECTOMY AND ADJUVANT CHEMOTHERAPY FOR LOCALLY ADVANCED GASTRIC CANCER by V. Yu. Skoropad, S. G. Afanasyev, S. V. Gamayunov, T. A. Agababyan, M. Yu. Volkov, S. A. Glushchenko, L. V. Evdokimov, K. S. Korchagina, S. A. Mozerov, O. A. Mikhaylova, N. O. Popova, G. O. Rukhadze, E. N. Samtsov, M. A. Safonova, A. A. Sveklova, Zh. A. Startseva, L. N. Titova, Z. K. Yakushina

“…Patients of the second (control) group will be treated with D2 gastrectomy and adjuvant chemotherapy. …”
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Dragonfly Molecular Diagnostic Platform: A Rapid Point-of-Care Solution for Monkeypox and Skin Lesion Pathogens by Dr Kenny Cardenas, Dr Matthew Cavuto, Dr Marcus Pond, Dr Ivana Pennisi, Mr Sohail Mirza, Mr Mark Comer, Dr Isobel Stokes, Dr Sian Lant, Dr Rebecca P Sumner, Dr Luca Miglietta, Dr Frankie Bolt, Prof Alison Holmes, Prof Shiranee Sriskandan, Dr David O Ulaeto, Dr Carlos Maluquer de Motes, Dr Jesus Rodriguez-Manzano

“…Introduction: The WHO's declaration of a monkeypox (mpox) clade II outbreak as a Public Health Emergency of International Concern in 2022 underscored the global threat posed by this virus. …”
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Donation after circulatory death heart transplantation using normothermic regional perfusion:The NYU ProtocolCentral MessagePerspective by Les James, MD, MPH, V. Reed LaSala, MD, Fredrick Hill, RN, CCP, Jennie Y. Ngai, MD, Alex Reyentovich, MD, Syed T. Hussain, MD, Claudia Gidea, MD, Greta L. Piper, MD, Aubrey C. Galloway, MD, Deane E. Smith, MD, Nader Moazami, MD

“…The remainder of the procurement, including the abdominal organs, proceeds in a similar controlled fashion as is performed for a standard donation after brain death donor. …”
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Treatment of the Cirrhotic Patients Considering Portal Hypertension Severity Degree and Comorbid Syntropic Extrahepatic Lesions, their Complications: Modified Algorithm, its Effect... by Ferko M.

“…According to the results of an ultrasound dopplerfloumetric examination of the abdominal cavity vessels, all the patients were stratified into three groups: the first – patients with I degree portal hypertension – 122 persons [33 women (27.0 %) and 89 men (73.0 %), aged 21 to 78 years (average age 46,4 ± 1,0 years), including 78 patients (57.4 %), for whicha comprehensive differentiated treatment with the help of modified by us algorithm was conducted (experimental group) and 44 patients (42.3 %), for which there was conducted a comprehensive treatment due to the conventional method (Order of the MPH of Ukraine from 13.06.2005, N 271 – the control group), the second patients with II degree portal hypertension – 57 patients [14 women (24.6 %) and 43 men (75.4 %) aged 27 to 66 years (average age 48,2 ± 1,3 years), including 26 persons (19.1 %) – experimental group and 31 patients (29.8 %) – control group], the third group – patients with III degree portal hypertension – 61 patients [18 women (29.5 %) and 43 men (70.5 %) aged 29 to 73 years (average age 50,2 ± 1,3 years), including 32 patients (23.5 %) – experimental group and 29 patients (27.9 %) – the control group]. …”
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Efectos de programas basados en artes marciales sobre rasgos autistas en niños y adolescentes: una revisión sistemática (Effects of martial arts programs based on autistic traits i... by Igor Cigarroa, Cristobal Riquelme-Hernández, Juan Pablo Reyes-Barría, Abner Vargas, Rafael Zapata-Lamana, María Aurora Gutiérrez Echavarría, Sonia Sepúlveda-Martin, David Toloza-Ramírez, Sandra Maruntoiu

“…También, se ha evidenciado que las artes marciales son una intervención efectiva en el control de la sintomatología de niños, niñas y adolescentes con TEA. …”
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A multidisciplinary approach to mental illness: do inflammation, telomere length and microbiota form a loop? A protocol for a cross-sectional study on the complex relationship betw... by Mirko Manchia, Pasquale Paribello, Carlo Arzedi, Alberto Bocchetta, Paola Caria, Cristina Cocco, Donatella Congiu, Eleonora Cossu, Tinuccia Dettori, Daniela V Frau, Mario Garzilli, Elias Manca, Anna Meloni, Maria A Montis, Andrea Mura, Mariella Nieddu, Barbara Noli, Federica Pinna, Claudia Pisanu, Renato Robledo, Giovanni Severino, Valeria Sogos, Caterina Chillotti, Bernardo Carpiniello, Maria Del Zompo, Gian Luca Ferri, Roberta Vanni, Alessio Squassina

“…The study is conducted in accordance with the principles of good clinical practice and the Declaration of Helsinki, and in compliance with the relevant Italian national legislation. …”
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Standards of specialized diabetes care. Edited by Dedov II, Shestakova MV, Mayorov AY. 8th edition by Ivan I. Dedov, Marina V. Shestakova, Aleksandr Y. Mayorov, Olga K. Vikulova, Gagik R. Galstyan, Tamara L Kuraeva, Valentina A. Peterkova, Olga M Smirnova, Elena G. Starostina, Elena V. Surkova, Olga Y. Sukhareva, Alla Y. Tokmakova, Minara S. Shamkhalova, Ivona Renata Jarek-Martynova, Diana D. Beshlieva, Olga N. Bondarenko, Natalya N. Volevodz, Olga R. Grigoryan, Roza M. Esayan, Liudmila I. Ibragimova, Viktor Y. Kalashnikov, Dmitry V. Lipatov, Ekaterina A. Shestakova

“…These observations resulted in the UN Resolution on Diabetes 61/225 passed on 20.12.2006, and in 2011 - UN Political Declaration, addressed to national health systems, calling for the establishment of multidisciplinary strategy in the prevention and control of non-communicable diseases, where special attention is drawn to the problem of diabetes as one of the leading causes of disability and mortality. …”
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Dependence of Indicators of Daily Blood Pressure Monitoring on Activity of Pathological Process in Patients with Systemic Lupus Erythematosus by Abrahamovych O., Abrahamovych U., Kushyna A., Guta S., Synenkyi O.

“…For all the examined patients were applied the principles of the Helsinki Declaration of Human Rights, the European Convention on Human Rights and Biomedicine. …”
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COVID-19 in Africa amidst an ongoing Ebola Virus Disease Outbreak in DRC. How prepared is the continent? by Sheba Nakacubo Gitta, Rebecca Babirye, Herbert Kazoora, Simon Nyovuura Antara

“…They have been involved in conducting preparedness assessments, point of entry screening and surveillance of suspected cases, developing protocols and guidelines for surveillance, infection prevention and control, risk communication and community engagement activities. …”
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