Protocol for a randomised controlled trial of the combined effects of the GLP-1 receptor agonist liraglutide and exercise on maintenance of weight loss and health after a very low-... by Mads Rosenkilde, Bente Merete Stallknecht, Simon Birk Kjær Jensen, Julie Rehné Lundgren, Charlotte Janus, Christian Rimer Juhl, Lisa Møller Olsen, Sten Madsbad, Signe Sørensen Torekov

“…The trial will be conducted in agreement with the Declaration of Helsinki and monitored to follow the guidelines for good clinical practice. …”
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Multicentre, open-label, randomised, controlled trial to compare early intervention with calcimimetics and conventional therapy in preventing coronary artery calcification in patie... by Yukio Yuzawa, Daijo Inaguma, Soshiro Ogata, Hideki Kawai, Yoshitaka Tatematsu, Naoki Okamoto, Eiichi Watanabe, Midori Hasegawa, Naotake Tsuboi

“…Therefore, this study will evaluate the efficacy and safety of early intervention with upacicalcet, a calcimimetic used to prevent coronary artery calcification in this patient population.Methods and analysis This multicentre, open-label, randomised, parallel-group controlled study will compare an early intervention group, which received upacicalcet and a low-dose VDRA, with a conventional therapy group, which received a VDRA. …”
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Prenatal multiple micronutrient-fortified balanced energy-protein supplementation and newborn telomere length and mitochondrial DNA content: a randomized controlled efficacy trial... by Giles T. Hanley-Cook, Yuri Bastos-Moreira, Dries S. Martens, Trenton Dailey-Chwalibóg, Laeticia Celine Toe, Brenda de Kok, Lionel OIivier Ouédraogo, Alemayehu Argaw, Kokeb Tesfamariam, Patrick Kolsteren, Lieven Huybregts, Tim S. Nawrot, Sarah De Saeger, Marthe De Boevre, Carl Lachat

“…The effect on markers of health and disease, such as offspring telomere length (TL) and mitochondrial DNA content (mtDNAc) is unknown.ObjectivesWe assessed the efficacy of maternal multiple micronutrient (MMN)-fortified balanced-energy protein (BEP) and iron-folic acid (IFA) supplementation on newborn TL as a secondary outcome and mtDNAc as a non-declared outcome.DesignWe conducted a randomized controlled trial in rural Burkina Faso, among pregnant females (15-40 years old) enrolled at < 21 weeks of gestation. …”
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Endoscopic variceal ligation combined with carvedilol versus endoscopic variceal ligation combined with propranolol for the treatment of oesophageal variceal bleeding in cirrhosis:... by Jing Wang, Meng Li, Lei Wang, Li Zhang, Ling Yang, Jian Wang, Duolao Wang, Rong Wang, Ya Peng, Chao Ma, Yiling Li, Yi Chen, Jing Xu, Xiaolong Qi, Hua Ye, Zhendong Jin, Hongyun Zhao, Wei Yan, Liwei Zhang, Chuan Liu, Andres Cardenas, Li Du, Ying Song, Biao Xie, Zhi Wei, Jianzhou Li, Wenhui Zhang, Qinghua Pan, Huiling Xiang, Shaoting Zhang, Shuairan Zhang, Xuan Liang, Shengjuan Hu, Lijun Peng, Xiaojie Zhang, Jingyi Xu, Xiaochao Liu, Huanhai Xu, Zhixu Fan, Lichun Shao, Pengyuan He, Qianlong Li, Yunhai Wu, Liyao Zhang, Dianliang Fang, Quanke Li, Dongli Xia, Yuchen Lv, Zongchao Zhang, Chaoguang Yan, Yuxia Wan, Haiming Fang, Wenlong Yang, Xiangman Zhang, Wei Rao, Xiurong Xia, Qiang Qiao, Ruimiao Yu, Changzhen Ren, Yuejun Yang, Zhenzhen Zhai, Xuejin Liu, Xingjun Lu, Yansheng Jia

“…The study will follow the Declaration of Helsinki and Good Clinical Practice guidelines. …”
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Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised,... by Alberto Papi, Bradley E Chipps, Frank C Albers, Laurence Reilly, Eva Johnsson, Christy Cappelletti

“…The primary efficacy endpoint was time-to-first severe asthma exacerbation.Ethics and dissemination The study was conducted in accordance with the ethical principles that have their origin in the Declaration of Helsinki, and that are consistent with International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use and Good Clinical Practice and the applicable regulatory requirements.Trial registration NCT03769090.…”
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‘Transauricular vagus nerve stimulation’ for prevention of postoperative delirium in elderly patients undergoing major surgery: a study protocol for a multicentre, participant-blin... by Jun Zhang, Xin Yu, Gang Chen, Yu Li, Qi-Hong Shen, Xinru Lin, Tieshuai Liu, Yunyun Yu, Keqin Song

“…The study will be performed according to the guidelines of the Declaration of Helsinki. Written informed consent will be obtained from all participants. …”
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Seizure prophylaxis following aneurysmal subarachnoid haemorrhage (SPSAH): study protocol for a multicentre randomised placebo-controlled trial of short-term sodium valproate proph... by Qiaowei Wu, Yuqi Chen, Chao You, Yuchen Li, Bowen Sun, Jianmin Zhang, Xin Hu, Pei Wu, Mei Fang, Zhiyi Xie, Honggang Wu, Shancai Xu, Bo Pang, Niandong Zheng

“…All analyses are by intention-to-treat.Ethics and dissemination This study will be conducted according to the principles of Declaration of Helsinki and good clinical practice guidelines. …”
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The internal auditing the organizational culture and its specificity within the international standards for the professional practice: Analytical theory study by Mouna Kechat

“…These declarations are evident in the set of standards 2100, "The Nature of Work". …”
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COVID-19 Measures and Human Dignity in Colombia: Restrictions of Fundamental Rights in Bogotá and Valle de Aburrá during the March-June 2020 Period by Gladis Cecilia Villegas Arias

“…The goal of this article is to analyze the impact that the regulations issued under the national lockdown declared by the Colombian government during the crisis caused by COVID-19 had on human dignity. …”
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Anthrax Outbreaks in Kyotera District, Uganda: Implications for Public Health Emergency Preparedness by Majani Edward, Francis Ogwang, Samuel Ojera, Francis Obaa

“…ABSTRACT Introduction In late 2023, Uganda's Ministry of Health declared an anthrax outbreak in the Kyotera district, Masaka region, following reported animal and human fatalities. …”
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Total and Bioaccessible contents of Microelements in Multivitamin Formulations Exposed to Consumption in Brazil using in vitro Gastrointestinal Digestion (INFOGEST Protocol) by Abdon Luiz Ornelas Latif, Thaís Luz de Sousa, Laura Beatriz Souza e Souza, Ivana Ferreira Simões, Alex Sander Lopes da Silva, Daniele Cristina Muniz Batista Santos, Aníbal de Freitas Santos Júnior, Clícia Maria de Jesus Benevides

“…The results revealed low bioaccessible contents (%) of Cu (0 to 23.8), Fe (0 to 15.7), Mn (0 to 11.4), and Zn (0 to 9.7), emphasizing the importance of regulation and quality control for consumer confidence. Conclusion: The analysis of Brazilian MFs raised significant concerns, as most samples did not reach 50 % of the total declared content. …”
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Effectiveness of Kushal Maa, a group-based mhealth interactive education and social support intervention for maternal and neonatal health outcomes: study protocol for a multisite r... by Praveen Kumar, Lakshmi Gopalakrishnan, Nadia Diamond-Smith, Azaz Khan, Abhishek Singh, Rashmi Bagga, Alison M El Ayadi, Anant Bhan, Alka Ahuja, Pushpendra Singh, Mona Duggal, Jasmeet Kaur, Deepak Tugnawat, Tracy Lin, Sujata Saunik, Garima Singh Verma, Shailendrakumar Gujarathi, Dinesh Chandke, Shashi Kant Dhir, Supriya Dhakne-Palwe, Mrunal Patil, Sonam Kumar, Nitin Vasaikar, Laura Weil

“…All research activities will be performed in accordance with the Declaration of Helsinki. On completion, findings will be disseminated to stakeholders through diverse strategies. …”
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Evaluating the effects of liraglutide, empagliflozin and linagliptin on mild cognitive impairment remission in patients with type 2 diabetes (LIGHT-MCI): study protocol for a multi... by Jie Liu, Jie Zhang, Wen Zhang, Ying Wang, Lu Zhang, Bing Zhang, Kun Wang, Weili Yan, Yan Bi, Zhou Zhang, Xiang Xu, Wenhui Zhu, Fangyi Li, Xiaoya Zhang, Xiaowei Zhu, Congcong Yu, Huijie Yang, Shihua Chen, Sijue Yang, Beibei Zhai, Tianyu Wu, Shengyi Zhao, Xuewei Tong, Yanjie Duan, Yining Chao, Jindan Wu, Xinhua Ye, Haiyan Cheng

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mHealth intervention (mTB-Tobacco) for smoking cessation in people with drug-sensitive pulmonary tuberculosis in Bangladesh and Pakistan: protocol for an adaptive design, cluster r... by Rumana Huque, John Norrie, Kamran Siddiqi, Melanie Boeckmann, Mahmoud Danaee, Ai Keow Lim, Steve Parrott, Amina Khan, Saeed Ansaari, Maham Zahid, Fahmidur Rahman, Asiful Chowdhury, Shakhawat Hossain Rana

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Structured home-based exercise programme and concentric versus eccentric-based stair training programme for pain and function in knee osteoarthritis: a two-phase, double-blinded, r... by Feroz Kabir, Sharmila Jahan, Ehsanur Rahman, Kazi Md Azman Hossain, Kazi Md Amran Hossain, Ambika Kormoker, Md Zahirul Islam, Md Kabir Hossain, Jannatul Ferdous Rikti, Abid Hasan Khan, Sharna Yesmin Suraiya, Md Zahid Hossain

“…In Phase I, there will be a 1:1 split of participants into: an HEP and a control group PI for 8 weeks. In Phase II, eligible participants from Phase I will be a 1:1:1 split into: a CSTP, an ESTP and a control group PII for another 8 weeks. …”
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Determinants of meconium aspiration syndrome among neonates admitted to neonatal intensive care unit at Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, South Eth... by Seifu Awgchew, Elias Ezo

“…Adjusted odds ratio with a 95% confidence interval was calculated, and statistical significance was declared at a p value less than 0.05. Result: Two hundred forty-nine (83 cases and 166 controls) mothers with their respective neonates were included in this study and that made the overall response rate 100%. …”
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Determinants of neonatal near misses among neonates admitted to Guji and Borena zones selected public hospitals, Southern Ethiopia, 2021: A facility based unmatched case control st... by Anteneh Fikrie, Elias Amaje, Amana Jilo Bonkiye, Wako Golicha Wako, Alqeer Aliyo, Takala Utura, Nurye Sirage, Boko Loka

“…Finally, Adjusted Odds Ratio together with 95% Confidence Intervals and p value <0.05 was used to declare the significance of all statistic. A total of 134 cases (neonatal near misses) and 268 controls (normal neonate) were participated in this study to make a response rate of 100% for both cases, and controls. …”
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Multicentre, prospective, single-arm, non-controlled, open-label trial to evaluate the safety and efficacy of live attenuated influenza vaccine in paediatric patients with atopic d... by Yuzaburo Inoue, Shuichi Suzuki, Minako Tomiita, Toshiyuki Kobayashi, Hiromichi Hamada, Yoshihito Ozawa, Takeshi Yamamoto, Hironori Sato, Koo Nagasawa, Eri Hayata, Saori Tanaka, Erika Kurihara, Taiji Nakano, Fumiya Yamaide, Takayasu Arima, Naruhiko Ishiwada

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Impact of the Social Credit System in China on Political Communication by O. A. Antoncheva, T. E. Apanasenko

“…Assessment by a learned community trying to comprehend the social credit system in terms of the paradigm of authoritarian government analyzed.The results of the consideration of market indicators show that the introduction of the social credit system did not have an impact on business climate indicators such as BCI or PMI.Meanwhile, for the sake of business climate indicators, the social credit system was introduced, as was stated when it was created: this system was designed to prevent unscrupulous behavior of frms. Thus, the declared goal of introducing a social credit system was not achieved.It seems logical to wonder if there was a different goal from the declared goal of introducing social credit, the goal of strengthening the tendency of authoritarian government.At the same time, point studies of the assessment of the social credit system by the population showed a high level of approval of social credit by citizens.Western liberal thought with its cult of individualism sees the following consequences of the introduction of a social credit system: violation of human rights, non-observance of the principle of social justice, violation of the principle of privacy, violation of the principle of equality of rights, development of totalitarian and authoritarian tendencies.It is assumed that some conclusions based on this approach may be called into question due to a mismatch of values: it is proved that assessment categories based on the values of extreme individualism are poorly applied to Chinese society, whose ideology is based on collectivist values.In this regard, a fundamentally different approach is applied to assessing the social credit system: signs of authoritarianism are postulated as the presence of unequal opportunities for symbolic construction of reality; the social credit system is tested for such capabilities within the theory of mass communication.The social credit system used to control the content of Internet sites will have an extremely negative impact on political communication, making it more asymmetric, on the democratic structure of the political system and human quality.…”
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Acinetobacter baumannii Virulence Factors, Resistance Mechanisms, and New Insights on Infection Treatment by Riham A. EL- Hakeem, Sarra E. Saleh, Mohammad M. Aboulwafa, Nadia A. Hassouna

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