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68201
Real-World Observations in the Treatment of Aortic Stenosis With the Transfemoral SAPIEN 3 Transcatheter Heart Valve: Insights From China
Published 2025-05-01“…However, China’s unique patient population presents distinct challenges, including a higher prevalence of bicuspid aortic valves (BAVs) and severe valve calcification. This study used real-world clinical data from Chinese patients to assess the safety and efficacy of the SAPIEN 3 balloon-expandable transcatheter heart valve (THV) in TAVR, particularly in patients with BAVs. …”
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68202
Variation in Relative Abundance of Small Mammal Species Caught in Two Different Ecosystems and Implicated in the Spread of Emerging Pathogens in Mali
Published 2024-10-01“…We used the data collected from this small mammal population with different eco-climatic characteristics to test hypothesis that small mammal distribution in different eco-climatic settings could explain the diversity and frequency of pathogens they carry. …”
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68203
Prognostic Value of Serum and Bronchoalveolar Lavage Fluid Galactomannan Levels in Invasive Aspergillosis: An 8-Year Experience at a Tertiary Cancer Center
Published 2025-05-01“…<b>Background:</b> Invasive aspergillosis (IA) is a life-threatening fungal infection that primarily affects immunocompromised individuals and has high morbidity and mortality rates, necessitating timely diagnosis and treatment. …”
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68204
The nasal mycobiome of individuals with allergic rhinitis and asthma differs from that of healthy controls in composition, structure and function
Published 2024-12-01“…This study contributes valuable fungal data and results to understand the relationships between the nasal mycobiome and allergy-related conditions. …”
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68205
An Integrated Approach Utilizing Single-Cell and Bulk RNA-Sequencing for the Identification of a Mitophagy-Associated Genes Signature: Implications for Prognostication and Therapeu...
Published 2025-01-01“…Stratifying patients by molecular subtypes may identify those who could benefit from immunotherapy. <b>Methods</b>: We used single-cell and bulk RNA sequencing data from GEO and TCGA databases. …”
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68206
Expression of Toll-like Receptor Genes and Antiviral Cytokines in Macrophage-like Cells in Response to Indole-3-carboxylic Acid Derivative
Published 2024-10-01“…In this study, real-time PCR methods were used to obtain data on the transcriptional activity of genes in macrophage-like cells. …”
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68207
Global, Regional, and National Burden of Breast Cancer in Adolescents and Young Adults Aged 15–39 Years From 1990 to 2021 Based on the Global Burden of Disease Study 2021
Published 2025-08-01“…Conclusions The global burden of AYA BC has increased significantly, particularly in regions with a middle and low SDI. …”
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68208
The efficacy and safety of divozilimab in patient with systemic sclerosis: 48-week results of the randomized double-blind placebo-controlled phase III clinical study LIBERIUS
Published 2025-05-01“…Infusions of DIV 250 mg were administered on weeks 0 and 2, and DIV 500 mg – on week 24 with the subsequent use in open mode, starting from week 48. This publication presents data obtained for 48 weeks of trial (before the DIV infusion at week 48). …”
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68209
Systematic identification of pathogenic variants of non-small cell lung cancer in the promoters of DNA-damage repair genesResearch in context
Published 2024-12-01“…Summary: Background: Deficiency in DNA-damage repair (DDR) genes, often due to disruptive coding variants, is linked to higher cancer risk. Our previous study has revealed the association between rare loss-of-function variants in DDR genes and the risk of lung cancer. …”
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68210
Comprehensive immune profiling and predictive modelling of paediatric acute hepatitis of unknown aetiology from a Spanish cohort
Published 2025-06-01“…IntroductionPaediatric acute hepatitis of unknown aetiology (PAHUA) has emerged as a global health concern, yet its cause remains unidentified. …”
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68211
Seroprevalence of dengue in the Democratic Republic of Congo, Ghana and Senegal: results of the SERODEN study
Published 2025-03-01“…Introduction: There are limited data on dengue transmission across most of African countries, including Senegal, Ghana, and the Democratic Republic of the Congo (DRC). …”
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68212
Radio Afterglows from Tidal Disruption Events: An Unbiased Sample from ASKAP RACS
Published 2024-01-01“…Detailed studies of some of these TDEs at radio wavelengths are also challenging the existing models for radio emission. Using all-sky multiepoch data from the Australian Square Kilometre Array Pathfinder (ASKAP), taken as a part of the Rapid ASKAP Continuum Survey (RACS), we searched for radio counterparts to a sample of optically discovered TDEs. …”
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68213
Real-world outcomes for young adult patients receiving CD19 CAR T-cell therapy
Published 2025-06-01“…A distinct analysis of YAs receiving commercial CD19 CAR T has not been reported. Using retrospective data from the Pediatric Real-World CAR T Consortium and the Real-World Outcomes of CAR T in Adult ALL collaboration, we describe the efficacy and safety of tisa-cel and brexu-cel in 70 YAs (18-26 years; tisa-cel, n = 50; brexu-cel, n = 20). …”
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68214
Biostratigraphy of the Gurpi Formation in Chenareh section based on calcareous nannofossils
Published 2024-06-01“…In many cases, in sediments with soft lithology such as the Gurpi Formation, using calcareous nannofossils, it leads to achieving a very clear biostratigraphic classification. …”
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68215
Rethinking the feasibility and safety of venetoclax-obinutuzumab in chronic lymphocytic leukemia: non-traditional factors may play a role in clinical practice
Published 2025-06-01“…Venetoclax-obinutuzumab (VO) has demonstrated efficacy in both fit and unfit patients in clinical trials, yet real-world data remain limited. …”
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68216
Transforming the Health Research Workforce in Mozambique: Achievements of the Mozambique Institute for Health Education and Research (MIHER) over a 13-Year Journey
Published 2024-12-01“…Objective: The manuscript provides an overview and discusses lessons learned about the pioneering role of the Mozambique Institute for Health Education and Research (MIHER) as the first research support center (RSC) in supporting the management of research grants in Mozambique, emphasizing its impact on research capacity development. Methods: Using mixed methods, data were comprehensively collected to identify MIHER’s primary achievements from 2010 to 2023. …”
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68217
Impact of Virtual Care With Remote Automated Monitoring on the Rate of Acute Hospital Care Post Discharge and Index Length of Hospital Stay: Protocol for the Post Discharge After S...
Published 2025-06-01“…Nurses review these data and conduct scheduled virtual visits (days 1, 3, 7, and 14). …”
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68218
Correction: “Impact of Virtual Care With Remote Automated Monitoring on the Rate of Acute Hospital Care Post Discharge and Index Length of Hospital Stay: Protocol for the Post Disc...
Published 2025-07-01“…Nurses review these data and conduct scheduled virtual visits (days 1, 3, 7, and 14). …”
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68219
Sequelae of preterm birth over the lifespan: an exploratory analysis of behavioral problems in childhood and increased risk of major depression and anxiety in adulthood from a coho...
Published 2025-07-01“…The cohort consists of individuals who were either born preterm or at term from 1969 to 2002. Data collection occurred between 2019 and 2021. This exploratory analysis used multivariable logistic regression to assess the impact of prematurity and fetal growth restriction on adult mental health outcomes (measured by the “Patient Health Questionnaire”), adjusting for age, gender, and socioeconomic status. …”
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68220
NRF1-Induced lncRNA DDX11-AS1 Contributes to the Progression of Hepatocellular Carcinoma via Activating CA9 Expression and the MEK/ERK Pathway
Published 2025-05-01“…RNA fluorescence in situ hybridization (RNA-FISH) was used to observe the subcellular localization of DDX11-AS1 in HCC cells. …”
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