Effects of different fruit loads on berry maturity and quality in grape cultivar “Yinhong” by Lu Meidan, He Kun, Pei Qingsong, Jia Huijuan

“…“Yinhong” grape (Vitis vinifera×Vitis labrusca) cultivar has many excellent characteristics, such as strong resistance, high branching rate and extensive management. …”
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Experience with Tixagevimab and Cilgavimab (Evusheld) in 86 rheumatic patients undergoing anti-B cell therapy with rituximab by T. V. Beketova, N. О. Levina, M. V. Dubinskaia, Yu. A. Uskova, I. V. Rozanova, V. V. Babak, M. F. Beketova, T. N. Krasnova

“…In the control group, 3 (7%) patients were diagnosed with COVID-19, one with severe lung injury (CT 3, pulmonary embolism) and death.Conclusions. The data of clinical studies and our own clinical experience evidence the effectiveness of the use of a combination of long-acting monoclonal antibodies TC (Evusheld), registered for indications for pre-exposure prophylaxis and treatment of COVID-19. …”
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Breaking prolonged sitting with high-intensity interval training to improve cognitive and brain health in middle-aged and older adults: a protocol for the pilot feasibility HIIT2SI... by Charles Hillman, Talha Syed, Dominika M Pindus, Tomasz S Ligeza, Jin Kuang, Scott Paluska, Joseph So, Miroslaw Wyczesany, Jesus Sarol, Flor B Quiroz, Ramiya Shanmugam, Maciej Kos, Naiman Khan, Art Kramer

“…In contrast, the effects of shorter (<10 min) PA bouts used to interrupt prolonged sitting on neurocognitive functions remain poorly understood. …”
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Vertical profiles of global tropospheric nitrogen dioxide (NO₂) obtained by cloud slicing the TROPOspheric Monitoring Instrument (TROPOMI) by R. P. Horner, E. A. Marais, N. Wei, R. G. Ryan, R. G. Ryan, V. Shah, V. Shah

“…We use cloud-sliced NO<span class="inline-formula">₂</span> to critique current knowledge of the vertical distribution of global NO<span class="inline-formula">₂</span>, as simulated by the GEOS-Chem chemical transport model, which has been updated to include peroxypropionyl nitrate (PPN) and aerosol nitrate photolysis, liberating NO<span class="inline-formula">₂</span> in the lower troposphere and mid-troposphere for aerosol nitrate photolysis and in the upper troposphere for PPN. …”
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Comparison of Perioperative Outcomes of Holmium Laser Enucleation of the Prostate for Standard (≤149 ml) Versus Very Large (≥150 ml) Prostate Glands: Retrospective Analysis of a Pr... by Jacob Schmidt, Jorien Krediet, Holger Beutel, Ayoub Hidayat Allah, Nella Gagel, Isabel Lichy, Bernhard Ralla, Maha Ullmann, Robert Peters, Frank Friedersdorff, Martin Kanne

“…Methods: We retrospectively analyzed data for 1815 adult patients who underwent HoLEP at Evangelisches Krankenhaus Königin Elisabeth Herzberge, Berlin, between January 2019 and May 2024. …”
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Thinking- Skins by Jens Böke

“…They are connected to a digital twin and can exchange data with each other via a communication protocol. …”
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INSTALLATION IN THE POST-INTERNET ERA / ИНСТАЛЛЯЦИЯ В ЭПОХУ ПОСТИНТЕРНЕТА by BOKHOROV KONSTANTIN Y. / БОХОРОВ К.Ю.

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Effectiveness of fermentation broth of Cordyceps sinensis for primary insomnia: a randomized clinical trial with digital health tool by Shuting Zhao, Ziqian Wang, Ziqian Wang, Xiaxia Fan, Xiaxia Fan, Xuanhao Shu, Xuanhao Shu, Qiao Chen, Yibo Zhou, Yongzhi Fu, Zheng Yu, Marcin Grzegorzek, Marcin Grzegorzek, Xinyu Huang, Chengwen Zheng, Chengwen Zheng, Yanxiong Gan, Chuanbiao Wen, Chuanbiao Wen

“…Lastly, Daytime Function scores decreased by −0.73 vs. −0.07 at Day 14 and −0.95 vs. −0.18 at Day 28.ConclusionThe FBCS demonstrated significant effectiveness in improving overall sleep outcomes among patients with primary insomnia. Moreover, the use of DHT enhanced patient adherence and facilitated reliable data collection.Clinical trial registrationhttps://www.chictr.org.cn/searchprojEN.html, identifier ChiCTR2100051187.…”
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The research beamlines at the Dresden proton therapy facility: available infrastructure and experimental capabilities by Felix Horst, Felix Horst, Elisabeth Bodenstein, Elisabeth Bodenstein, Michael Baumann, Michael Baumann, Elke Beyreuther, Elke Beyreuther, Jozef Bokor, Wolfgang Enghardt, Wolfgang Enghardt, Sebastian Gantz, Martin Hejzlar, Fritz Kurth, Markus Meyer, Stefan Pieck, Stefan Pieck, Stefan Pieck, Christian Richter, Christian Richter, Christian Richter, Jörg Pawelke, Jörg Pawelke

“…The present work describes the technical characteristics and provides measured beam data of these two complementary beamlines, one delivering scanned beams with quasi-clinical parameters and the other one stationary continuous and pulsed pencil beams with parameters exceeding the clinically used range. …”
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Post Mortem Findings of Cetaceans Stranded Along the Campania Coast from 2016 to 2022 by Emanuele Esposito, Maria Oliviero, Doriana Iaccarino, Gianluigi Paduano, Francesco Serra, Martina Levante, Maria Grazia Amoroso, Clementina Auriemma, Amalia Gallo, Maria Gabriella Lucibelli, Agata Campione, Roberta Rispoli, Francesca Menafro, Francesca Bove, Maria Dimatteo, Marianna D’Amore, Barbara Degli Uberti, Virginia Mattioda, Federica Giorda, Carla Grattarola, Guido Pietroluongo, Cinzia Centelleghe, Giovanna Fusco, Esterina De Carlo, Fabio Di Nocera

“…Moreover, even with a lower frequency, other relevant pathogens like <i>Photobacterium damselae</i>, <i>Salmonella enteritidis</i>, <i>Erysipelothrix rhusiopathiae</i>, and <i>Chlamydia abortus</i> were isolated. These data were useful to understand the spread and circulation of these pathogens, some zoonotic, in the coastal marine waters of the Campania region.…”
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Characterization of tongue coating microbiome from patients with colorectal cancer by Qubo Chen, Xiaoting Huang, Haiyan Zhang, Xuanting Jiang, Xuan Zeng, Wanhua Li, Hairong Su, Ying Chen, Fengye Lin, Man Li, Xiangyu Gu, Huihui Jin, Ruohan Wang, Dechang Diao, Wei Wang, Jin Li, Sufen Wei, Weizheng Zhang, Wofeng Liu, Zhiping Huang, Yusheng Deng, Wen Luo, Zuofeng Liu, Beiping Zhang

“…Importantly, various species across participants jointly shaped three distinguishable fur types.The tongue coating microbiome profiling data gave an area under the receiver operating characteristic curve (AUC) of 0.915 in discriminating CRC patients from control participants; species such as Atopobium rimae, Streptococcus sanguinis, and Prevotella oris aided differentiation of CRC patients from healthy participants.Conclusion These results elucidate the use of tongue coating microbiome in CRC patients firstly, and the fur-types observed contribute to a better understanding of the microbial community in human. …”
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Searching for GEMS: Confirmation of TOI-5573 b, a Cool, Saturn-like Planet Orbiting an M Dwarf by Rachel B. Fernandes, Shubham Kanodia, Megan Delamer, Andrew Hotnisky, Te Han, Caleb I. Cañas, Jessica Libby-Roberts, Varghese Reji, Arvind F. Gupta, Jaime A. Alvarado-Montes, Chad F. Bender, Cullen H. Blake, William D. Cochran, Zoë L. de Beurs, Scott A. Diddams, Jiayin Dong, Mark E. Everett, Eric B. Ford, Samuel Halverson, Jesus Higuera, Henry A. Kobulnicky, Daniel M. Krolikowski, Alexander Larsen, Andrea S.J. Lin, Suvrath Mahadevan, Michael W. McElwain, Andrew Monson, Joe P. Ninan, Leonardo A. Paredes, Yatrik G. Patel, Paul Robertson, Gabrielle Ross, Arpita Roy, Christian Schwab, Gudmundur Stefansson, Daniel J. Stevens, Andrew M. Vanderburg, Jason Wright

“…The planet was initially discovered by the Transiting Exoplanet Survey Satellite (TESS) and confirmed using a combination of 11 transits from four TESS Sectors (20, 21, 47, and 74), ground-based photometry from the Red Buttes Observatory, and high-precision radial velocity data from the Habitable-zone Planet Finder and NN-EXPLORE Exoplanet Investigations with Doppler spectrographs, achieving a 5 σ precision on the planet’s mass. …”
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Insights into immune-related adverse events in colorectal cancer patients receiving neoadjuvant immunotherapy: findings from a multicenter registry study by Chentong Wang, Quan Wang, Jiaolin Zhou, Aiping Zhou, Xiaojian Wu, Guanyu Yu, Lei Zhou, Yuping Zhu, Weijie Chen, Xiaoyuan Qiu, Liting Sun, Yang Gong, Xiao Zhang, Ganbin Li, Yang An, Han Chen, Xiaoyu Xie, Jinhua Tao, Guole Lin, Hongwei Yao, Wei Zhang

“…BackgroundThe growing use of immune checkpoint inhibitors (ICIs) in the neoadjuvant treatment of colorectal cancer (CRC) has highlighted immune-related adverse events (irAEs) as a major concern. …”
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Lower Frequency of PNPLA3 Polymorphism in West African Populations and Divergent Associations With Hepatocellular Carcinoma by Perapa Chotiprasidhi, Yvonne Ayerki Nartey, Karina Sato-Espinoza, Robert A. Vierkant, Jun Ma, Yaw Awuku, Adwoa Agyei-Nkansah, Mary Afihene, Amoako Duah, Sally Bampoh, Shadrack Asibey, Joshua Ayawin, Jun Wang, Yinan Zheng, Lifang Hou, Claudia Hawkins, Robert Murphy, Godwin Imade, Edith Okeke, Alani Akanmu, Olufunmilayo Lesi, Amelie Plymoth, Jose D. Debes, Lewis R. Roberts, Samuel O. Antwi, Kirk J. Wangensteen

“…Germline genetic sequencing was performed, and data on PNPLA3-rs738409 were extracted for analysis. …”
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Deubiquitinating enzyme USP2 regulates brown adipose tissue thermogenesis via controlling EBF2 stabilization by Yuejie Xu, Ying Chen, Ningning Bai, Yingying Su, Yafen Ye, Rong Zhang, Ying Yang, Caizhi Liu, Cheng Hu, Jiemin Pan

“…Results: USP2 is upregulated upon thermogenic activation in adipose, and has a close correlation with UCP1 mRNA levels in human adipose tissue. …”
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Inflammatory markers in pregnancy – identifying drivers in four large cohorts by Frederieke A. J. Gigase, Frederieke A. J. Gigase, Anna Suleri, Anna Suleri, Elena Isaevska, Elena Isaevska, Anna-Sophie Rommel, Myrthe G. B. M. Boekhorst, Olga Dmitrichenko, Hanan El Marroun, Hanan El Marroun, Eric A. P. Steegers, Manon H. J. Hillegers, Ryan L. Muetzel, Ryan L. Muetzel, Whitney Lieb, Charlotte A. M. Cecil, Charlotte A. M. Cecil, Charlotte A. M. Cecil, Victor J. M. Pop, Michael Breen, Veerle Bergink, Veerle Bergink, Veerle Bergink, Lot D. de Witte, Lot D. de Witte, Lot D. de Witte

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Detecting white adipose tissue browning in mice with in vivo R2∗ mapping at 9.4T MRI by Qiaoling Zhong, Hongsheng Liu, Yanqiu Feng, Xiuwei Jiao, Yuanbo Yang, Daming Zhang, Qian Wang, Zoheb Ahasan, Andrew Z. Li, Chong Wee Liew, Zimeng Cai, Zaiyi Liu, Kejia Cai

“…Currently, fat-water fraction (FWF) has been used as a marker for the loss of lipids associated with WAT browning. …”
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Preclinical validation of electrospun fibers to achieve vaginal colonization by Lactobacillus crispatus by Christy N. Armstrong, Christy N. Armstrong, Sudeshna Saha, Sudeshna Saha, Marnie A. Aagard, Marnie A. Aagard, Mohamed Y. Mahmoud, Mohamed Y. Mahmoud, Nissi M. Varki, Nissi M. Varki, Nissi M. Varki, Nicole M. Gilbert, Nicole M. Gilbert, Hermann B. Frieboes, Hermann B. Frieboes, Hermann B. Frieboes, Hermann B. Frieboes, Warren G. Lewis, Warren G. Lewis, Amanda L. Lewis, Amanda L. Lewis

“…Lactobacillus crispatus is widely believed to contribute to a healthy vaginal microbiome, and its therapeutic application has shown promise in early clinical trials investigating adjunct therapies for lasting treatment of conditions such as BV. …”
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Development of a zoonotic influenza distribution assessment and ranking system (ZIDAR): Technical application in Nepal to support cross-sectoral risk-based surveillance by Adam Charette-Castonguay, Dipendra Gautam, Binay Shrestha, Hemant Chandra Ojha, Barun Kumar Sharma, Mukul Upadhayaya, Sujan Rana, Roshika Shrestha, Lok Bandu Chaudhary, Bhawana Kandel, Rudra Prasad Marasini, Sharmila Chapagain, Tulsi Ram Gompo, Surendra Karki, Apsara Poudel, Saugat Shrestha, Avinash Sunny Kayastha, Arun Kumar Govindakarnavar, Reuben Samuel, Allison Gocotano, Pushpa Ranjan Wijesinghe, Nilesh Buddha, Edwin Ceniza Salvador, Manish Kakkar, Ricardo J. Soares Magalhães

“…While spatial risk assessments have been used to map vulnerable areas, their applicability across multiple sectors has been so far limited. …”
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Evaluation of a Hub-and-Spoke Model to Enhance Healthcare Professionals’ Practice of Antimicrobial Stewardship (AMS) Programmes in the Volta Region of Ghana by Mairead McErlean, Eneyi Kpokiri, Preet Panesar, Emily E. Cooper, Jonathan Jato, Emmanuel Orman, Hayford Odoi, Araba Hutton-Nyameaye, Samuel O. Somuah, Isaac Folitse, Thelma A. Aku, Inemesit O. Ben, Melissa Farragher, Leila Hail, Cornelius C. Dodoo, Yogini H. Jani

“…A hub-and-spoke model, decentralising expertise and distributing resources to peripheral facilities, has been proposed as a strategy to enhance the antimicrobial stewardship (AMS) capacity in low- and middle-income countries. …”
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