Mechanistic insights into the cardiovascular effects of acute heat exposure: A multi-omics analysis based on a randomized crossover trial by Xinlei Zhu, Xihao Du, Yixiang Zhu, Lu Zhou, Cong Liu, Yue Niu, Qingli Zhang, Yixuan Jiang, Haidong Kan, Renjie Chen

“…Linear mixed-effects models were used to analyze the data. The pathway enrichment was performed at the ingenuity pathway analysis platform. …”
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Revisiting hemodynamic definition: Incidence of chronic thromboembolic pulmonary hypertension following acute intermediate-high and high-risk pulmonary embolism by Bárbara Lacerda Teixeira, André Grazina, Ricardo Carvalheiro, Tiago Mendonça, Tiago Pereira da Silva, António Fiarresga, Ruben Ramos, Duarte Cacela, João Reis, Ana Galrinho, Luís Almeida Morais, Rui Cruz Ferreira

“…Methods: A prospective registry of consecutive intermediate-high- and high-risk PE patients submitted to catheter directed therapies (CDT) in a tertiary center was used. Clinical, echocardiographic, computed tomography angiography (CTA), right heart catheterization (RHC) and digital subtraction pulmonary angiogram (DSPA) data were collected at admission and at 3 months. …”
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Balancing accuracy and user satisfaction: the role of prompt engineering in AI-driven healthcare solutions by Mini Han Wang, Mini Han Wang, Mini Han Wang, Mini Han Wang, Mini Han Wang, Xudong Jiang, Xudong Jiang, Xudong Jiang, Xudong Jiang, Peijin Zeng, Peijin Zeng, Peijin Zeng, Xinyue Li, Kelvin Kam-Lung Chong, Guanghui Hou, Xiaoxiao Fang, Yang Yu, Xiangrong Yu, Junbin Fang, Yi Pan

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Adverse reactions following first three doses of the BNT162b2 mRNA COVID-19 vaccine: A prospective cohort study on relationships with individual characteristics and previous experi... by Ayako Konishi, Wakaba Fukushima, Tomoka Matsuura, Satoko Ohfuji, Tetsuo Kase, Kyoko Kondo, Kazuhiro Matsumoto, Asae Suita, Emiko Mukai, Ayane Kasamatsu, Yasutoshi Kido, Yu Nakagama, Yuko Nitahara, Yukihiro Kaneko, Akira Kaneko, Etsuko Nakagami-Yamaguchi, Hiroshi Kakeya, Yoshio Hirota

“…Modified Poisson regression models were used to examine the association of adverse reactions. …”
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Prediction of primary biliary cholangitis among health check-up population with anti-mitochondrial M2 antibody positive by Haolong Li, Song Liu, Xu Wang, Xinxin Feng, Siyu Wang, Yanli Zhang, Fengchun Zhang, Li Wang, Tengda Xu, Yongzhe Li

“…The prediction model based on ALP, GGT, IgM, EOS%, gamma globulin percentage, HGB, and sex has a certain predictive ability for the occurrence of PBC in this population.…”
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Short-term effects of extreme air pollutant concentrations on coronary heart disease hospitalization in Henan province: a time-stratified case-crossover study by Shuming Liu, Yongbin Wang, Lujie Wang, Xuefang Li, Menghui Fei, Pingshuan Dong, Kan Yang, Hui Liu, Na Xie, Hengwen Chen, Guang Chen, Huan Li, Xiayan Zang, Jun Li, Zhigang Chen, Fei Lin, Fei Lin, Guoan Zhao, Guoan Zhao

“…Data on 133,294 confirmed CHD patients from seven large hospitals across five cities (2016–2021) were collected, with patients' addresses linked to nearby air quality monitoring stations to assess exposure to air pollutants and meteorological factors. …”
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Assessing the context within academic health institutions toward improving equity-based, community and patient-engaged research by Prajakta Adsul, Shannon Sanchez-Youngman, Elizabeth Dickson, Belkis Jacquez, Alena Kuhlemeier, Michael Muhammad, Katherine J. Briant, Bridgette Hempstead, Jason A. Mendoza, Lisa G. Rosas, Anisha Patel, Patricia Rodriguez Espinosa, Tabia Akintobi, Paige Castro-Reyes, Lori Carter-Edwards, Nina Wallerstein

“… Abstract Introduction The continued momentum toward equity-based, patient/community-engaged research (P/CenR) is pushing health sciences to embrace principles of community-based participatory research. Much of this progress has hinged on individual patient/community–academic partnered research projects and partnerships with minimal institutional support from their academic health institutions. …”
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Search for and Analysis of Eclipsing Binaries in the LAMOST Medium-resolution Survey Field. I. R.A.: 23h01m51s, Decl.: +34°36′45″ by Jing-Yi Wang, Kai Li, Xiang Gao, Di-Fu Guo, Li-Heng Wang, Dong-Yang Gao, Ling-Zhi Li, Ya-Ni Guo, Xing Gao, Guo-You Sun

“…By analyzing photometric data in the the Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) Medium-Resolution Survey field, R.A.: 23 ^h 01 ^m 51 $\mathop{.}…”
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The STROGHAT study protocol: An intervention study to evaluate safety, effectiveness and feasibility of treating gambiense HAT seropositive subjects with acoziborole. [version 1; p... by Veerle Lejon, Raquel Inocencio Da Luz, Craig Tipple, Catiane Vander Kelen, Rian Snijders, Nick Van Reet, Stijn Rogé, Paul Verlé, Antoine Tarral, Epco Hasker, Elena Nicco, Dieudonné Mumba, Erick Mwamba Miaka, Charles Kambo, Alain Mpanya, Wilfried Mutombo, Digas Ngolo, Sandra Rembry, Stéphane Hugonnet

“…The STROGHAT study aims to evaluate whether this approach can lead to elimination of T.b. gambiense from its human reservoir, and to provide further safety data on acoziborole. It also includes a costing analysis and a prospective evaluation of the performance of the screening and diagnostic tests used. …”
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Time trends in malaria incidence from 1992 to 2021 in high-risk regions: An age‑period‑cohort analysis based on the Global Burden of Disease study 2021 by Yu Cao, Hao Wu, Yongping Zhang, Xueyi Wu, Jingjing Li, Hanwu Chen, Wei Gao

“…This study aims to analyze malaria incidence globally, identify high-risk regions, and examine long-term trends in incidence to provide important evidence for malaria eradication. Methods: We used data from the Global Burden of Disease Study 2021, applying the age-period-cohort model to estimate the effects of age, period, and cohort on malaria incidence from 1992 to 2021. …”
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Comparison of a preventive or curative strategy of fluid removal on the weaning of mechanical ventilation: a study protocol for a multicentre randomised open-label parallel-group t... by Vincent Labbe, Gwenaël Prat, Guylaine Labro, Jean-Pierre Quenot, Jean-Paul Mira, Martin Dres, Armand Mekontso Dessap, François Beloncle, Laurent Guérin, Candice Estellat, Arnaud Galbois, Jean-Luc Baudel, Julien Cousty, Jordane Lebut

“…Introduction Fluid overload is associated with a poor prognosis in the critically ill patients, especially at the time of weaning from mechanical ventilation as it may promote weaning failure from cardiac origin. Some data suggest that early administration of diuretics would shorten the duration of mechanical ventilation. …”
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Indigenous rights-based approaches to decolonising research methodologies in settler colonial contexts by Peter Anderson, Zane M. Diamond, Thu Pham, Angela Baeza Peña, Carla Tapia, Levon Blue, Melanie Saward, Angelina Hurley, Kate Pecar, Amanda Kelly, Owen Forbes, Veronica Goerke, Jeane Diamond, Abby Cathcart, Chizu Sato, Koji Maeda, Russell Fox, Wren D. W. Howe

“…After working collaboratively, it became possible to analyse the similarities and differences in the use of IBRA across various fields of study.ResultsOur analysis reveals five key aspects that were revealed during the implementation of the Indigenous rights-based approach: (1) Indigenous People as Data, (2) Protocols of engagement, (3) Privileging Indigenous Knowledge Systems, (4) Community Benefit, and (5) Tackling Doctoral Research Training.DiscussionWe found that an Indigenous rights-based approach is crucial for decolonising research in settler colonial states such as Australia. …”
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Factors associated with attitudes towards HIV cure research among transgender women and travestis: a cross-sectional survey in São Paulo, Brazil by Vivian Iida Avelino-Silva, Robert J Wozniak, Natalia B Cerqueira, Maria Candida S Dantas, Bianca Mahafe, Daniel A C Barros, Edmilson Alves de Medeiros, Ana Carolina Soares de Oliveira, Thiago Sabino, Albert Roggenbuck, Carrie D Johnston, Jez L Marston, Sebastian C Bidegain, Manya Magnus, Esper G Kallas, Douglas F Nixon, Camila S Donini

“…Objective Characterising the perceptions of groups most affected by HIV is fundamental in establishing guidelines for biomedical advancement. Although Brazil has successfully fought HIV/AIDS through several measures, transgender women still have a likelihood of HIV infection 55 times higher than the general population. …”
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Farmers’ Perception of Ecosystem Services Provided by Historical Rubber Plantations in Sankuru Province, DR Congo by Joël Mobunda Tiko, Serge Shakanye Ndjadi, Jémima Lydie OBANDZA - AYESSA, Daniel Botshumo Banga, Julien Bwazani Balandi, Charles Mumbere Musavandalo, Jean Pierre Mate Mweru, Baudouin Michel, Olivia Lovanirina Rakotondrasoa, Jean Pierre Meniko To Hulu

“…Particular attention will be paid to the farmers’ perceptions of these services, an essential element for the rational management of natural resources. This study used a mixed methodological approach, integrating semi-structured interviews, focus groups, and statistical analyses including chi-square testing and multiple correspondence factorial analysis (MCAFA) to obtain and analyze the data comprehensively. …”
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Socio-economic inequalities in minimum dietary diversity among Ethiopian children aged 6–23 months: a decomposition analysis by Nigusu Worku, Amare Mesfin Workie, Lamrot Yohannes, Mihret Getnet, Mihret Getnet, Wubshet Debebe Negash, Wubshet Debebe Negash, Adina Yeshambel Belay, Lakew Asmare, Hiwot Tadesse Alemu, Demiss Mulatu Geberu, Melak Jejaw, Kaleb Assegid Demissie, Misganaw Guadie Tiruneh, Asebe Hagos

“…For a long time, Ethiopia has suffered from the double burden of malnutrition: overnutrition and undernutrition both pose significant challenges, particularly for children. …”
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Triphenyl phosphate induces lipid metabolism disorder and promotes obesity through PI3K/AKT signaling pathway by Tianlan Li, Yiwa Liu, Jingyi Cao, Xianzhu Lu, Yinghan Lu, Yuhan Wang, Chunmei Zhang, Meifen Wu, Song Deng, Li Li, Ming Shi

“…Triphenyl phosphate (TPHP) is a widely used organic phosphate flame retardant that has been reported as a potential environmental obesogen. …”
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The role of protein-phenolic interactions in the formation of red wine colloidal particles by Matteo Marangon, Valentina Marassi, Fulvio Mattivi, Christine Mayr Marangon, Luigi Moio, Barbara Roda, Luca Rolle, Maurizio Ugliano, Andrea Versari, Sara Zanella, Andrea Curioni

“…The compactness of these colloidal particles has been linked to the wine’s protein content, with colloidal particles containing higher protein levels being less compact. …”
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Outcomes of fenestrated-branched endovascular aortic repair of thoracoabdominal aortic aneurysms in patients with heritable thoracic aortic diseasesCentral MessagePerspective by Lucas Ribé, MD, Lucas Ruiter Kanamori, MD, Bruno P. Schmid, MD, Thanila A. Macedo, MD, Bernardo C. Mendes, MD, Steven Maximus, MD, Ying Huang, MD, PhD, Felipe Nasser, MD, PhD, Gustavo S. Oderich, MD

“…Fenestrated-branched endovascular aortic repair (FB-EVAR) has been used selectively in higher-risk patients. …”
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Spatiotemporal analysis of Anopheles gambiae larval sites and malaria transmission in Djilakh, Central Senegal by Assane Ndiaye, Camille Morlighem, Aminata Niang Diène, Moussa Kane, Abdoulaye Diallo, Fassiatou Tairou, Mohamed Abderemane Nourdine, Pape Cheikh Sarr, Lassana Konaté, Ousmane Faye, Oumar Gaye, El Hadji Amadou Niang, Catherine Linard, Ousmane Sy

“…Abstract Background The progress made against malaria has resulted in a nationwide reduction of the disease burden in Senegal. …”
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Hypoperfusion Intensity Ratio as an Indirect Imaging Surrogate in Patients With Anterior Circulation Large‐Vessel Occlusion and Association of Baseline Characteristics With Poor Co... by Omar Hamam, Julie Gudenkauf, Rawan Moustafa, Andrew Cho, Daniel Montes, Muhannad Sharara, Abdallah Moustafa, Mahla Radmard, Mehreen Nabi, Kevin Chen, Sadra Sepehri, Christopher Shin, Ishan Mazumdar, Minsoo Kim, Alireza Mohseni, Ajay Malhotra, Javier Romero, Vivek Yedavalli

“…Hypoperfusion intensity ratio has been previously validated as an indirect noninvasive pretreatment imaging biomarker of CS. …”
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