Augmenting precision medicine via targeted RNA-Seq detection of expressed mutations by Dan Li, Jianying Li, Donald J. Johann, Daniel Butler, Guangchun Chen, Jonathan Foox, Binsheng Gong, Wendell Jones, David P. Kreil, Rebecca Kusko, Paweł P. Łabaj, Anne Bergstrom Lucas, Christopher E. Mason, Christopher Mozsary, Natalia Novoradovskaya, Carlos Pabón-Peña, Bohu Pan, Todd A. Richmond, Roberta Maestro, Sayed Mohammad Ebrahim Sahraeian, Andreas Scherer, Hagen U. Tilgner, James C. Willey, Pierre R. Bushel, Joshua Xu

“…While RNA sequencing (RNA-seq) has been increasingly used alongside DNA cancer mutation screening panels to assess the impact of variants on gene transcript expression and splicing, comprehensive evaluations of RNA panels and the integration of expressed mutation data analytics to supplement DNA panels are still limited. …”
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FaceReader as a neuromarketing tool to compare the olfactory preferences of customers in selected markets by Jakub Berčík, Anna Mravcová, Esther Sendra Nadal, David Bernardo López Lluch, Andrea Farkaš

“…The main contribution of this work lies in the new opportunities to obtain feedback that can be used in marketing research and that rely not only on explicit but also implicit data. …”
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Antiviral efficacy of fluoxetine in early symptomatic COVID-19: an open-label, randomised, controlled, adaptive platform trial (PLATCOV)Research in context by Podjanee Jittamala, Simon Boyd, William H.K. Schilling, James A. Watson, Thundon Ngamprasertchai, Tanaya Siripoon, Viravarn Luvira, Elizabeth M. Batty, Phrutsamon Wongnak, Lisia M. Esper, Pedro J. Almeida, Cintia Cruz, Fernando R. Ascencao, Renato S. Aguiar, Najia K. Ghanchi, James J. Callery, Shivani Singh, Varaporn Kruabkontho, Thatsanun Ngernseng, Jaruwan Tubprasert, Wanassanan Madmanee, Kanokon Suwannasin, Amornrat Promsongsil, Borimas Hanboonkunupakarn, Kittiyod Poovorawan, Manus Potaporn, Attasit Srisubat, Bootsakorn Loharjun, Walter R.J. Taylor, Farah Qamar, Abdul Momin Kazi, M. Asim Beg, Danoy Chommanam, Sisouphanh Vidhamaly, Kesinee Chotivanich, Mallika Imwong, Sasithon Pukrittayakamee, Arjen M. Dondorp, Nicholas P.J. Day, Mauro M. Teixeira, Watcharapong Piyaphanee, Weerapong Phumratanaprapin, Nicholas J. White

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高敏感特質中高齡學習者面對數位學習壓力及疫情焦慮之學習滿意度與後疫情調適：復原力之中介效果 Learning Satisfaction and Post-Pandemic Adaptation in Highly Sensitive Middle-aged and Elderly Learners in the Face of Digital Learni... by 王雅鈴 Ya-Ling Wang, 張伶瑜 Lin-Yu Chang, 羅淇文 Chi-Wen Luo, 林郁文 Yu-Wen Lin

“…A total of 208 valid responses were collected (72 male, 136 female, mean age = 57.93, SD = 6.79). The collected data were analyzed using structural equation modeling (SEM) with the Bootstrap statistical method for mediation analysis. …”
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Multi-instrument Search for Gamma-Ray Counterpart of X-Ray Transients Detected by EP/WXT by Yan-Qiu Zhang, Wang-Chen Xue, Jin-Peng Zhang, Ce Cai, Shao-Lin Xiong, Cheng-Kui Li, Yuan Liu, Chen-Wei Wang, Hao-Xuan Guo, Shuo Xiao, Wen-Jun Tan, Chao Zheng, Jia-Cong Liu, Sheng-Lun Xie, Peng Zhang, Wen-Long Zhang, Yue Wang, Zheng-Hang Yu, Yang-Zhao Ren, Ping Wang, Yue Huang, Xiao-Bo Li, Xiao-Yun Zhao, Shi-Jie Zheng, Zhen Zhang, Shu-Xu Yi, Li-Ming Song, Shuang-Nan Zhang

“…In this work, we implemented a comprehensive targeted search for gamma-ray counterparts to 63 X-ray transients reported by EP/WXT during its first year of operation, using the dedicated multiple-instrument search pipeline, Energetic Transients Joint Analysis System for Multi-Instrument (ETJASMIN), with GECAM-B, GECAM-C, Fermi/GBM, and Insight-HXMT data. …”
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Deep learning integration of chest computed tomography and plasma proteomics to identify novel aspects of severe COVID-19 pneumonia by Yucai Hong, Lin Chen, Yang Yu, Ziyue Zhao, Ronghua Wu, Rui Gong, Yandong Cheng, Lingmin Yuan, Shaojun Zheng, Cheng Zheng, Ronghai Lin, Jianping Chen, Kangwei Sun, Ping Xu, Li Ye, Chaoting Han, Xihao Zhou, Yaqing Liu, Jianhua Yu, Yaqin Zheng, Jie Yang, Jiajie Huang, Juan Chen, Junjie Fang, Chensong Chen, Bo Fan, Honglong Fang, Baning Ye, Xiyun Chen, Xiaoli Qian, Junxiang Chen, Haitao Yu, Jun Zhang, Xi-Ming Pan, Yi-Xing Zhan, You-Hai Zheng, Zhang-Hong Huang, Chao Zhong, Ning Liu, Hongying Ni, Gengsheng Zhang, Zhongheng Zhang

“…Quantification of plasma proteins was achieved using the Olink® inflammation panel. A deep learning model was meticulously trained, with CSRL features serving as input and the proteomic data as the target. …”
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A systematic review on the assessment of pregnancy-specific psychological trauma during pregnancy: A call to action by Soudabeh Givrad, MD, Kathryn M. Wall, Lindsey Wallace Goldman, Jin Young Shin, Eloise H. Novak, Amanda Lowell, Francesca Penner, Michèle J. Day, Lea Papa, Drew Wright, Helena J.V. Rutherford

“…To build a knowledge base to develop future measure(s) of PSPT, we conducted a systematic review to understand how and when PSPT has been measured during pregnancy. Data sources: Searches were run in July 2021 on the following databases: Ovid MEDLINE (In‐Process & Other Non‐Indexed Citations and Ovid MEDLINE 1946 to Present), Ovid EMBASE (1974 to present), Scopus, Web of Science, PsycInfo, and Cochrane. …”
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Carboprost versus Oxytocin as the first-line treatment of primary postpartum haemorrhage (COPE): protocol for a phase IV, double-blind, double-dummy, randomised controlled trial an... by Kerry Woolfall, Ben Hardwick, Dimitrios Siassakos, Andrew Shennan, Stephen Robson, Dyfrig A Hughes, Carrol Gamble, Elizabeth Deja, Andrew Weeks, Peter Collins, Jim Thornton, Kirtana Vallabhaneni, Tina Lavender, Gillian Gyte, Helen Hickey, Egle Saviciute, Anna Rosala-Hallas, Efstathia Gkioni, Kim Hinshaw, Catrin Plumpton, Shireen Meher, Annette L Briley, Rachel E Collis, Charlotte Van Netten, Dilly Anumba, Sion Kenyon, Elaine Willis

“…Due to the emergency nature of PPH, COPE uses a research without prior consent (RWPC) model. …”
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Prevalence, risk factors and treatment outcomes of isoniazid resistant TB in Bulawayo city, Zimbabwe: A cohort study by Barbara Manyame-Murwira, Kudakwashe Collins Takarinda, Pruthu Thekkur, Bright Payera, Herbert Mutunzi, Raiva Simbi, Nicholas Siziba, Edwin Sibanda, Catherine Banana, Norbert Muleya, Evidence Makombe, Paula Littia Jongwe, Regina Bhebhe, Douglas Mangwanya, Janet Dzangare, Fungai Hamilton Mudzengerere, Collins Timire, Enock Wekiya, Charles Sandy

“…Zimbabwe, one of the high TB burden countries, has not explored the burden of isoniazid resistant TB. …”
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Video-fluoroscopic swallowing study scale for predicting aspiration pneumonia in Parkinson's disease. by Satoshi Tomita, Tomoko Oeda, Atsushi Umemura, Masayuki Kohsaka, Kwiyoung Park, Kenji Yamamoto, Hiroshi Sugiyama, Hideyuki Sawada

“…Logistic regression analysis was performed to determine the prognostic VFSS features based on the data of swallowing 3 mL of jelly, which were used to make a PD VFSS scale (PDVFS). …”
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Circulating vaccine-derived poliovirus outbreak in Chiengi District, Zambia, September 2019 by Chipoya Musole, Kapina Muzala, Ngomah Albertina, Mwansa Dien Francis, Matapo Belem, Liwewe Maziyanga, Monze Mwaka, Zulu Paul, Kayeyi Nkomba, Situmbeko Mwangala, Simwaba Davis, Gama Angela, Sinyange Nyambe, Mukonka Victor

“…Introduction: Africa has seen a significant rise in circulating vaccine-derived polioviruses type 2 (cVDPV2) outbreaks following the switch to the bivalent oral polio vaccine (bOPV) in 2016. …”
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Clinical evaluation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections: a prospective study by Yaqin Peng, Ruijie Xie, Yifeng Luo, Yifeng Luo, Yifeng Luo, Penghao Guo, Zhongwen Wu, Yili Chen, Pingjuan Liu, Jiankai Deng, Bin Huang, Kang Liao

“…BackgroundThough droplet digital PCR (ddPCR) has emerged as a promising tool for early pathogen detection in bloodstream infections (BSIs), more studies are needed to support its clinical application widely due to different ddPCR platforms with discrepant diagnostic performance. …”
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The establishment of PD-1 inhibitor treatment prognosis model based on dynamic changes of peripheral blood indexes in patients with advanced lung squamous cell carcinoma by Yuyan Xie, Hao Sun, Liying Shan, Xin Ma, Qingyu Sun, Fang Liu

“…In recent years, immunotherapy has revolutionized the treatment approach for LUSC. …”
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Arjunolic acid from Rhodomyrtus tomentosa suppresses growth of non-small cell lung cancer via inducing autophagy and apoptosis by Ziying Huang, Chang Liu, Chenchen Zhang, Huanling Wu, Siqin Li, Caihong Wei, Yi Zhang, Zechi Xing, Minhui Lin, Guang Yang, Jiang Ma, Bin Jiang, Min Hong, Xin He, Ji Yang

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TREATMENT OF MYELOFIBROSIS: PRESENT AND FUTURE by Birsen Sahip Yesiralioğlu

“…Androgens, prednisone (can be used in addition to androgen therapy or alone), danazol, thymodomide, lenalidomide, erythropoiesis-stimulating agents (ESAs) can be used. …”
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Petrology and mineralogy of the Fenghuanshan granodiorite, Anhui Province, China: implications for petrogenesis and metallogenesis implication by Zhang Aiping, Yangsong Du, Yi Cao, Zhenshan Pang, Gan Luo, Kangkang Xu

“…Here, we investigate the petrography and mineralogy of the Fenghuangshan granodiorite, focusing on variations in amphibole composition and determining the conditions of amphibole crystallization. The data are used to determine the petrogenetic history and metallogenic significance of the hosting granodiorite. …”
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The role of geriatric nutritional risk index in predicting survival of type B aortic dissection patients after thoracic endovascular aortic repair by Kaiwen Zhao, Jinzhu Niu, Yuzhen He, Lingxu Kong, Wenyao Zhao, Qingsheng Lu, Shuangshuang Li, Jian Zhou

“…Methods: A total of 1,157 consecutive patients who underwent TEVAR between January 2007 and August 2019 were included, with data from 789 patients analyzed. The GNRI was used to measure nutritional status. …”
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Progression of the first stage of spontaneous labour: A prospective cohort study in two sub-Saharan African countries. by Olufemi T Oladapo, Joao Paulo Souza, Bukola Fawole, Kidza Mugerwa, Gleici Perdoná, Domingos Alves, Hayala Souza, Rodrigo Reis, Livia Oliveira-Ciabati, Alexandre Maiorano, Adesina Akintan, Francis E Alu, Lawal Oyeneyin, Amos Adebayo, Josaphat Byamugisha, Miriam Nakalembe, Hadiza A Idris, Ola Okike, Fernando Althabe, Vanora Hundley, France Donnay, Robert Pattinson, Harshadkumar C Sanghvi, Jen E Jardine, Özge Tunçalp, Joshua P Vogel, Mary Ellen Stanton, Meghan Bohren, Jun Zhang, Tina Lavender, Jerker Liljestrand, Petra Ten Hoope-Bender, Matthews Mathai, Rajiv Bahl, A Metin Gülmezoglu

“…<h4>Background</h4>Escalation in the global rates of labour interventions, particularly cesarean section and oxytocin augmentation, has renewed interest in a better understanding of natural labour progression. …”
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Construction of a Practical Oriented Tool for Evaluating the Ability of Community Medical Staff to Provide Hospice Care Services and Its Reliability and Validity by SHA Jingjing, JING Limei, DING Tongjiu, XIN Yurong, TANG Lan, LI Shuijing

“…Background Hospice care service has been practiced deeply in our country. Many cities have taken primary medical and health institutions as the prime places to carry out hospice care, such as in Shanghai. …”
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Targeting osteosarcopenia and multimorbidity for frailty prevention through identification and deep phenotyping methods in healthy ageing and high-burden disease cohorts (OPTIMA-C)... by Keng He Kong, Eng Sing Lee, Wee Shiong Lim, Sai Zhen Sim, Bryan Yijia Tan, Matthew Rong Jie Tay, Jong Moon Kim, Poo Lee Ong, Lay Wai Khin, Chin Jung Wong, Michael Gui Jie Yam, Justin Linghui Chew, Alvin Wai Kit Tan, Ananda Sidarta, Emily Yee, Karen Sui Geok Chua

“…Data collection will take place at postrecruitment baseline (hospital admission), 1, 6 months, 12 months and 2 years postrecruitment (inpatient) and at postrecruitment baseline, 6 months, 12 months and 2 years postrecruitment (outpatient).Ethics and dissemination Ethical approval has been obtained from the National Healthcare Group Domain Specific Review Board (2023/00105). …”
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