Simulation and zoning evaluation of in-situ stress field within ultra-deep tight sandstone reservoirs in thrust-nappe structures of Bozi-Dabei area, Tarim Basin by Zimeng XING, Ruixue LI, Hucheng DENG, Hang SU, Jiawei ZHANG, Jianhua HE, Hui ZHANG, Xiaofei HU, Shunting MA

“…Core testing, well logging, and mining field test data were used to calibrate the in-situ stress direction and magnitude for individual wells, and their distribution characteristics were analyzed. …”
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Synergistic Network Pharmacology: Preclinical Validation and Clinical Safety in Acute Ischemic Stroke by Ana I. Casas, Cristian Nogales, Rebecca D. Szepanowski, Mahmoud H. Elbatreek, Elisa Anastasi, Sepideh Sadegh, James Skelton, Benedikt Frank, Anil Wipat, Jan Baumbach, Christoph Kleinschnitz, Harald H. H. W. Schmidt

“…Systems medicine, instead, has a holistic approach and defines diseases in an organ‐agnostic manner on the basis of associated risk genes, their encoded proteins, and protein–protein interactions. …”
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Association Between Adolescent Violence Exposure and the Risk of Suicide: A 15-Year Study in Taiwan by Chieh Sung, Chi-Hsiang Chung, Chien-An Sun, Chang-Huei Tsao, Daphne Yih Ng, Tsu-Hsuan Weng, Li-Yun Fann, Fu-Huang Lin, Wu-Chien Chien

“…Background/Objectives: According to the 2023 Ministry of Health and Welfare statistics, the suicide rate among adolescents aged 15 to 24 has steadily increased since 2018, from 3.7 to 5.5 per 100,000 populations, reaching a recent high. …”
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Global, regional, and national burden of male breast cancer in 204 countries and territories: a systematic analysis from the global burden of disease study, 1990–2021Research in co... by Yunhai Li, Ying Huang, Hongbo Huang, Tingting Wei, Aijie Zhang, Lei Xing, Xuedong Yin, Hongyuan Li, Guosheng Ren, Fan Li

“…Summary: Background: Male breast cancer (MBC) is a rare malignancy that has been under-investigated, with limited global epidemiological research dedicated to it. …”
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The correlation between neutrophil/lymphocyte ratio and the MRI burden and cognitive function in patients with cerebral small vessel disease by Mengyao Zhao, Mengyao Zhao, Xiaohua Xie, Xiaohua Xie, Zhiwei Hao, Zhiwei Hao, Mengsi Ren, Zhenjie Teng, Zhenjie Teng, Jing Xu, Jing Xu, Chunhui Shan, Yanhong Dong, Yanhong Dong, Peiyuan Lv, Peiyuan Lv

“…ObjectiveAims to explore the relationship between neutrophil/lymphocyte ratio (NLR) and the total burden of imaging markers and cognitive function in patients with cerebral small vessel disease (CSVD).MethodsA retrospective study was conducted on 148 hospitalized CSVD patients at Hebei General Hospital from January 2022 to September 2024, with complete clinical and laboratory data. NLR was calculated as neutrophil count/lymphocyte count. …”
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Digital Biomarkers for Parkinson Disease: Bibliometric Analysis and a Scoping Review of Deep Learning for Freezing of Gait by Wenhao Qi, Shiying Shen, Chaoqun dong, Mengjiao Zhao, Shuaiqi Zang, Xiaohong Zhu, Jiaqi Li, Bin Wang, Yankai Shi, Yongze Dong, Huajuan Shen, Junling Kang, Xiaodong Lu, Guowei Jiang, Jingsong Du, Eryi Shu, Qingbo Zhou, Jinghua Wang, Shihua Cao

“… BackgroundWith the rapid development of digital biomarkers in Parkinson disease (PD) research, it has become increasingly important to explore the current research trends and key areas of focus. …”
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P-18 ANTI-HBC POSITIVITY IS AN INDEPENDENT PREDICTIVE FACTOR FOR HCC DEVELOPMENT AND SHOULD BE INCORPORATED TO THE HCC RISK SCORE PREDICTION MODEL IN ADVANCED FIBROSIS by Marcus Vinicius de Acevedo Garcia Gomes, Diogo Delgado Dotta, Manuella Andrade Oliveira Sobral, Isabela Bodaczny Taliberti, Alexandre Belucci Trazzi, Eduardo Pombo Nascimento, Betania da Silva Rocha, Patricia Momoyo Yoshimura Zitelli, Rosa Maria Nascimento Marcusso, Mario Guimaraes Pessoa

“…Demographic, clinical and laboratory data were obtained through electronic medical records. …”
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Impact of metabolic and nutritional disorders on the synergy between radiotherapy and immunotherapy in non-small-cell lung cancer by Haiyan Chen, Yaner Yu, Shuangqiu Zhu, Jian Zhao, Yan Ma, Zhifei Huang, Hao Jiang, Qichun Wei

“…Clinicopathological, metabolic and nutritional factors were collected to analyze their influence on progression-free survival (PFS), overall survival and abscopal control time. Abdominal CT was used to obtain body composition data including abdominal obesity and muscle mass. …”
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Gender-specific association between circulating 25-hydroxyvitamin D levels and diabetic retinopathy in patients with type 2 diabetes mellitus by Jing He, Jingrui Kang, Zhou Mei, Xiaohui Zhou, Yingchuan Yin, Cuiling Zhu

“…BackgroundDiabetic retinopathy (DR), one of the most common microvascular complications of diabetes mellitus (DM), remains to be a major driver of vision loss worldwide. Vitamin D has been reported to be involved in DR pathogenesis, but results have been inconsistent. …”
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Monocytes to lymphocytes multiplying platelets ratio as an early indicator of acute kidney injury in cardiac surgery with cardiopulmonary bypass: a retrospective analysis by Qian Li, Hong Lv, Yuye Chen, Jingjia Shen, Jia Shi, Fuxia Yan, Sheng Wang, Chenghui Zhou

“…However, the link between MLPR and acute kidney injury following cardiac surgery (CSA-AKI) with cardiopulmonary bypass (CPB) has not been investigated yet. We comprehensively explored the potential linear and nonlinear relationship between MLPR or MLR and CSA-AKI.Methods Data of patients who underwent cardiac surgery with CPB between December 2018 and April 2021 were retrospectively collected at Fuwai Hospital, Beijing, China. …”
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Analysis of etiological characteristics, risk factors and inflammatory factors in patients with postoperative infection following modified radical mastectomy by QIAN Fang, SUN Yongqiang, ZHANG Sihan, SONG Tianli

“…Methods: The clinical data of breast cancer patients admitted to the Third People's Hospital of Zhengzhou from February 2019 to February 2022 were analyzed retrospectively. …”
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Abstracts of the 13th European Conference on Eye Movements 2005 by Marina Groner, Rudolf Groner, R. Müri, Kazuo Koga, Simon Raess, P. Suri

“…This group included scientists who used eye movement registration as a research tool and developed models based on oculomotor data obtained from a wide spectrum of phenomena, ranging from the neurophysiological to the perceptual and the cognitive level. …”
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High‐Frequency Mutations in TP53, AXIN1, CTNNB1, and KRAS, and Polymorphisms in JAK1 Genes Among Mongolian HCC Patients by Nomin Bold, Khurelsukh Buyanbat, Ariya Enkhtuya, Nomin Myagmar, Gerelsuren Batbayar, Zolzaya Sandag, Dolgion Damdinbazar, Nomuun Oyunbat, Tuul Boldbaatar, Ankhbayar Enkhbaatar, Gan‐Erdene Baatarjav, Taivan Nanzaddorj, Tsendsuren Oyunsuren, Gantulga Davaakhuu

“…ABSTRACT Background Mongolia has the highest incidence of liver cancer worldwide, largely driven by a high prevalence of hepatitis virus infections. …”
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Circulating Tumor DNA Combining with Imaging Analysis for Lesion Detection of Langerhans Cell Histiocytosis in Children by Siying Liu, Yongbing Zhu, Yu Chen, Yaqin Wang, Dedong Zhang, Jiasi Zhang, Yao Wang, Ai Zhang, Qun Hu, Aiguo Liu

“…In this retrospective study, the significance of ctDNA and imaging in Langerhans cell histiocytosis (LCH) monitoring was first examined, and the broader role of ctDNA in monitoring LCH was additionally explored. Methods: First, data visualization and survival analysis models were used to generalize the concordance between cfBRAF^V600E molecular response and radiographic response on clinical outcomes. …”
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Prevalence of, and Factors Associated with Hemodynamic Instability Among Women Presenting with Incomplete Abortion at a Tertiary Hospital in Southwestern Uganda by Kakama C, Agaba DC, Byamukama O, Kajabwangu R, Kengonzi E, Akol MA, Muhumuza A, Businge J, Turanzomwe S, Ainomugisha B, Kalyebara KP, Kayondo M, Ngonzi J, Muganwa WG, Lugobe HM

“…We consecutively enrolled women with incomplete abortion and collected data on socio-demographic, abortion- and medical-related factors, and measured their blood pressure and heart rate at admission. …”
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Discovery and clinical translation of ceperognastat, an O‐GlcNAcase (OGA) inhibitor, for the treatment of Alzheimer's disease by William Kielbasa, Paul Goldsmith, Kevin B. Donnelly, Hugh N. Nuthall, Sergey Shcherbinin, Adam S. Fleisher, Jörg Hendle, Susan L. DuBois, Stephen L. Lowe, Feiyu Fred Zhang, Eric M. Woerly, Nicolas J.‐F. Dreyfus, David Evans, Jeremy Gilmore, Michele Mancini, Cristian C. Constantinescu, Roger N. Gunn, David S. Russell, Emily C. Collins, Miroslaw Brys, Michael L. Hutton, Dustin J. Mergott

“…Increased tau O‐GlcNAcylation has been shown to reduce tau pathology in mouse in vivo tauopathy models. …”
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The association of PD-L1 expression status and the PD-1/PD-L1 inhibitor-related toxicity profile in non-small cell lung cancer by Qian Zhu, Hao Hu, Li-Ying OuYang, Rong Yang, Wen-Xiao Wei, Pin Huang, Xin-Rong He

“…Furthermore, PD-L1 expression might be a useful biomarker for toxicity management in patients with NSCLC after PD-1/PD-L1 inhibitor treatment.…”
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Influencia de padres, amistades y profesorado en la actividad física y la capacidad aeróbica de los jóvenes (Influence of parents, friends and teachers on physical activity and ae... by Martí Xavier Bennàsser Torrandell, Josep Vidal Conti

“…T-tests and Pearson's correlation were used for data analysis. The study shows that young people who have friends who doing sports and who perceive that they are encouraged and supported by their parents to do sports, do more PA weekly hours, obtain healthier BMI and VO2max., and spend less time in front of screens. …”
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Research on the Influence Mechanism of “Scenery-Relics” Landscape on Public Spatio-Temporal Behavior and Perception Preference in Industrial Wasteland: A Case Study of Shougang Ind... by Sijia QIU, Lige BAO, Jing XU, Fang WEI

“…Moreover, the “Scenery-Relics” concept, as a novel form of green space, has demonstrated significant potential for transformation, offering new directions for enhancing ecosystem cultural services.MethodsThe spatio-temporal behavioral trajectory technique provides an accurate and efficient method for the research on public behavioral preferences in post-industrial landscapes. …”
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Exploration and application of deep learning based wellbore deformation forecasting model by Hui LIU, Guoqiang LI, Xiaojun ZHU, Pengfei ZHANG, Hua CHENG, Jinzheng WANG, Peishuai LI

“…The wellbore characteristic area and overall prediction effect are good, indicating that the wellbore deformation prediction model based on deep learning has good prediction ability. The research results have been effectively applied in the wellbore grouting repair and management project, which provides technical reference and data support for the safe management of wellbore, and provides engineering practical experience for similar projects.…”
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