SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study by Judith Breuer, Catherine F Houlihan, Nick Freemantle, David Partridge, Gaia Nebbia, Jacqui Prieto, Gee Yen Shin, Andrew Copas, Oliver Stirrup, Kenneth Laing, Rachel Williams, Helen Wheeler, Paul Randell, Ana da Silva Filipe, Maria-Teresa Cutino-Moguel, Tommy Rampling, Tabassum Khan, James Price, Eleni Nastouli, Katie Johnson, Sharon Glaysher, Scott Elliott, Helen Umpleby, Emanuela Pelosi, Emma Thomson, Cristina Venturini, Anna Riddell, Alison Cox, Andrew C Hayward, Malin Bergström, David Harrington, Charlotte Williams, Tanzina Haque, Dianne Irish, Adrienn Angyal, Marios Margaritis, Moira Spyer, Florencia Boshier, José Afonso Guerra-Assunção, Adela Alcolea-Medina, Angela Beckett, Themoula Charalampous, Raghavendran Kulasegaran Shylini, Beatrix Kele, Irene Monahan, Guy Mollett, Matthew Parker, Sunando Roy, Joshua Taylor, Sophie Weller, Eleri Wilson-Davies, Phillip Wade, Joseph Hughes, Tabitha Mahungu, Cassie Pope, Samuel Robson, Kordo Saeed, Thushan de Silva, Luke Snell, Adam A Witney, James Blackstone, Leanne Hockey, Georgia Marley, Christine Peters, Flavia Flaviani, Bindi Patel, Tom G S Williams, Rahul Batra, Jonathan D Edgeworth, Pinglawathee Madona, Jennifer Hart, Juanita Pang, Helena Tutill, Nadua Bayzid, Marius Cotic, Luke Green, Benjamin Lindsey, Amy State, Alison Cope, Peijun Zhang, Max Whiteley, Marta Gallis Ramalho, Stella Christou, Stavroula Louka, Hailey Hornsby, Benjamin Foulkes, Paige Wolverson, Joe Heffer, Nikki Smith, Salman Goudarzi, Chris Fearn, Kate Cook, Katie Loveson, Adhyana Mahamana, Buddhini Samaraweera, Siona Silveira, Stephen Aplin, Sarah Jeremiah, Matthew Harvey, Thea Sass, Ngee Keong Tan, Claudia Cardoso Pereira, Dan Frampton, Matt Byott, Judith Heaney, Emilie Sanchez, Stavroula M Paraskevopoulou

“…Associations between the variant and the outcomes of all-cause mortality and intensive therapy unit (ITU) admission were evaluated using mixed effects Cox models adjusted by age, sex, comorbidities, care home residence, pregnancy and ethnicity.Findings Sequences were obtained from 2341 inpatients (HOCI cases=786) and analysis of clinical outcomes was carried out in 2147 inpatients with all data available. …”
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DESI Mg ii Absorbers: Extinction Characteristics and Quasar Redshift Accuracy by Lucas Napolitano, Adam D. Myers, Victoria A. Fawcett, Jessica Aguilar, Steven Ahlen, Davide Bianchi, David Brooks, Todd Claybaugh, Shaun Cole, Axel de la Macorra, Biprateep Dey, Andreu Font-Ribera, Jaime E. Forero-Romero, Enrique Gaztañaga, Satya Gontcho A Gontcho, Gaston Gutierrez, Klaus Honscheid, Stephanie Juneau, Andrew Lambert, Martin Landriau, Laurent Le Guillou, Aaron Meisner, Ramon Miquel, John Moustakas, Jeffrey A. Newman, Francisco Prada, Ignasi Pérez-Ràfols, Graziano Rossi, Eusebio Sanchez, David Schlegel, Michael Schubnell, David Sprayberry, Gregory Tarlé, Benjamin Alan Weaver, Hu Zou

“…In this paper, we study how absorption-line systems affect the spectra and redshifts of quasi-stellar objects (QSOs), using catalogs of Mg ii absorbers from the early data release and first data release of the Dark Energy Spectroscopic Instrument. …”
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Habitat Characteristics and the Species Response of Astragalus curvirostris Boiss. to the Environmental Factors in Lorestan Rangelands by Reza Siahmansour, Nadia Kamali, Hamid Reza Mirdavoodi, Javad Motamedi

“…Extended Abstract IntroductionTo analyze complex ecological data, it is necessary to employ flexible and robust analytical methods that can handle non-linear relationships, interactions, and missing data control. …”
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The Evolution of Methotrexate Applications: A Multidimensional Approach to Treating Various Disorders – A Literature Review by Tomasz Tamborski, Michalina Zagalska, Adam Jan Ząbek, Jakub Paweł Kuźniar, Marta Turek, Adam Grzebinoga, Julia Szlążek, Barbara Roguska, Magdalena Szostak, Emilia Gabriela Chrzanowska

“…IntroductionMethotrexate (MTX) is a key cytostatic and immunosuppressive drug widely used in oncology and autoimmune disease treatment. …”
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Identification and characterization of long-term meteorological drought events in the Yellow River Basin by Jiepeng Li, Lajiao Chen, Geli Zhang, Hui Liu, Hongchang Hu, Mengzhen Xu, Xingyan Guo, Zibo Meng, Zhiqiang Dong

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Protocol for a multicentre, randomised, parallel-control, superiority trial comparing administration of clotting factor concentrates with a standard massive haemorrhage protocol in... by Neil Parry, Andrew Beckett, Jo Carroll, Homer Tien, Jeannie Callum, Andrew Petrosoniak, Damon Scales, Luis Teodoro da Luz, Keyvan Karkouti, Paul T Engels, Hans-Peter Hucke, Deep Grewal, Bruce Schwartz, Henry Peng

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Vitamin D in the prevention of exacerbations of asthma in preschoolers (DIVA): protocol for a multicentre randomised placebo-controlled triple-blind trial by Mohsen Sadatsafavi, Megan E Jensen, Francine M Ducharme, Nathalie Alos, Geneviève Mailhot, Benoît Mâsse, John H White, Ali Khamessan, Sze Man Tse, Reza Alizadehfar, Dirk E Bock, Patrick Daigneault, Chantal Lemire, Connie Yang, Dhenuka Radhakrishnan

“…It is associated with more URTIs and, in patients with asthma, more oral corticosteroid (OCS) use. Although evidence suggests that vitamin D supplements significantly decrease URTIs and asthma exacerbations requiring OCS, there is insufficient data in preschoolers. …”
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Increased risk of suicide among patients with social anxiety disorder by Han-Ting Wei, Shih-Jen Tsai, Chih-Ming Cheng, Wen-Han Chang, Ya-Mei Bai, Tung-Ping Su, Tzeng-Ji Chen, Mu-Hong Chen

“…Abstract Aims Increasing evidence has established a strong association between social anxiety disorder and suicidal behaviours, including suicidal ideation and suicide attempts. …”
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Incidence and Risk of Thromboembolic and Cardiovascular Adverse Events with PARP Inhibitor Treatment in Patients with Metastatic Castration-resistant Prostate Cancer: A Systematic... by Brigida Anna Maiorano, Martina Catalano, Chiara Mercinelli, Antonio Cigliola, Valentina Tateo, Neeraj Agarwal, Shilpa Gupta, Giandomenico Roviello, Andrea Necchi

“…Background and objective: PARP inhibitor (PARPi) treatment is an effective option for patients with metastatic castration-resistant prostate cancer (mCRPC). There are few data on the cardiovascular and thromboembolic safety of these agents in mCRPC, as cardiovascular and thromboembolic adverse events (AEs) are uncommon. …”
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Characteristics of Soil Nutrients Accumulation and Nitrogen and Phosphorus Loss of Greenhouse Vegetable Field by YANG Tao, CHEN Yuanhua, CHEN Feng, XU Changxu, ZHUANG Yanhua, TU Xiangming, CHEN Jingrui

“…［Methods］ Multipoint sampling was used for analysis cumulative amount of nutrients within the 0—100 cm depth soil layer in greenhouse vegetable throughout 11 cities and districts of this province, and in situ monitoring was used to analyze the characteristics of nitrogen and phosphorus loss. …”
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Infrared Satellite Detection Limits for Monitoring Atmospheric Ammonia by Mark W. Shephard, Shailesh K. Kharol, Enrico Dammers, Christopher E. Sioris, Andrew Bell, Rik Jansen, Jerome Caron, Ralph Snel, Emanuela Palombo, Karen E. Cady-Pereira, Chris A. McLinden, Erik Lutsch, Robert O. Knuteson

“…The detection level of ammonia is computed directly from simulated satellite ammonia spectral signatures, which has the advantage of being independent of retrieval methodologies. …”
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Association between trajectory of triglyceride-glucose index and all-cause mortality in critically ill patients with atrial fibrillation: a retrospective cohort study by Shangsong Shi, Feng Xue, Tingbo Jiang, Lin Ling

“…Methods We used data from Medical Information Mart for Intensive Care (MIMIC)-IV database. …”
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Consumption of vitamin A rich foods and its associated factors among children aged 6–59 months in North Shoa Zone, Oromia regional state, Ethiopia by Meseret Moroda, Girma Garedew Goyomsa, Rebik Shukure, Shelema Nigussu

“…A multistage stratified sampling followed by the simple random sampling technique was used to select the study participants. Data was collected through a face to face interview. …”
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The mediating effect of self-perceived aging on social capital and depression among Chinese community-dwelling older adult: a cross-sectional study by Yuguo Ye, Hui Liu, Ziming Wang, Qianwei Zhang, Shifan Yang, Lian Yang

“…Pearson correlation analysis was used to explore the correlations between social capital, self-perceived aging, and depression. …”
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Protocol for the Redefining Maternal Anemia in Pregnancy and Postpartum (ReMAPP) study: A multisite, international, population-based cohort study to establish global hemoglobin thr... by Emily R Smith, Zahra Hoodbhoy, Aneeta Hotwani, Fyezah Jehan, Amna Khan, Imran Nisar, Nida Yazdani, Santosh Joseph Benjamin, Anne George Cherian, Venkata Raghava Mohan, Sunitha Varghese, Balakrishnan Vijayalekshmi, Blair J Wylie, Leena Chatterjee, Arjun Dang, R Venketeshwar, Sasha G Baumann, Christopher Mores, Qing Pan, Christopher R Sudfeld, Victor Akelo, Winnie K Mwebia, Kephas Otieno, Gregory Ouma, Harun Owuor, Joyce Were, Dennis Adu-Gyasi, Veronica Agyemang, Sam Newton, Charlotte Tawiah, Arun Singh Jadaun, Sarmila Mazumder, Neeraj Sharma, Lynda G Ugwu, Amma Benneh-Akwasi Kuma, Bethany Freeman, Margaret P Kasaro, Felistas M Mbewe, Humphrey Mwape, Rachel S Resop, M Bridget Spelke, Kwaku Poku Asante, Redefining Maternal Anemia in Pregnancy and Postpartum (ReMAPP) Study Investigators

“…<h4>Strengths and limitations</h4>Novel study design to allow multiple analytical approaches (clinical decision limits and reference limits) in the same population to establish hemoglobin thresholds.Use of gold standard methods and external quality assurance programs to ensure harmonized hemoglobin measurement across sites.Inclusion of biomarker-intensive study arm to examine the etiology of anemia among pregnant women.All data is contributed by populations historically underrepresented in research in low- and middle-income countries.…”
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Impact of Antibiotic Stewardship on Treatment of Hospitalized Children with Skin and Soft-Tissue Infections by Giulia Brigadoi, Sara Rossin, Lorenzo Chiusaroli, Giulia Camilla Demarin, Linda Maestri, Francesca Tesser, Martina Matarazzo, Cecilia Liberati, Elisa Barbieri, Carlo Giaquinto, Liviana Da Dalt, Silvia Bressan, Daniele Donà

“…Overusing broad-spectrum antibiotics has contributed to rising antibiotic resistance, complicating treatment outcomes. …”
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Study of Liposomes Containing Extract from the Leaves of <i>Protium heptaphyllum</i> (Aubl.) March in Animals Submitted to a Mutagenic Model Induced by Cyclophosphamide by Naiéle Sartori Patias, Valéria Dornelles Gindri Sinhorin, Ana Júlia Lopes Braga Ferneda, João Maurício Andrade Ferneda, Marina Mariko Sugui, Stela Regina Ferrarini, Gisele Facholi Bomfim, Joaz Wellington Lopes, Nadia Aline Bobbi Antoniassi, Larissa Cavalheiro, Nelson Luís de Campos Domingues, Adilson Paulo Sinhorin

“…Cyclophosphamide (CPA) is an alkylating agent used as a chemotherapy agent in the treatment of cancer, but it has immunosuppressive effects. …”
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St. Louis enhancing engagement and retention (STEER) in HIV/AIDS care: a participatory intersectional needs assessment for intervention and implementation planning by Debbie L. Humphries, Phillip Marotta, Yue Hu, Victor Wang, Greg Gross, Darius Rucker, Johnnie Jones, Faiad Alam, Tawnya Brown, Donna Spiegelman, Chelsey R. Carter

“…A rapid qualitative analysis approach was used for all interviews and focus groups.ResultsThe IBPA was used to guide team discussions of team values, definition and framing of the problem, questions and topics in the key informant interviews, development of the logic model of the problem, and all results. …”
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Examining the Impact of Digital Inclusion on Depression Among Older Adults in China: Mediating Role of Noncognitive Abilities by Xinru Li, Chengyu Chen, Xiyan Li, Yuyang Li, Shujuan Xiao, Jianan Han, Yanan Wang, Chichen Zhang

“…Although existing literature has explored the relationship between the use of the internet and depression among older adults to some extent, it mainly focused on surface aspects rather than delving into the underlying mechanism of action among digital inclusion, depression, and noncognitive abilities, which remains unclear. …”
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Explanation of Good Governance Factors in Shiraz by Ehsan Heidarzadeh, Mojtaba Arasteh, Elnaz Rafiee

“…Recently the terms "governance" and "good governance" are being increasingly used in development literature. The concept of "governance" is not new. …”
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