House design and risk of malaria, acute respiratory infection and gastrointestinal illness in Uganda: A cohort study. by Alex K Musiime, Paul J Krezanoski, David L Smith, Maxwell Kilama, Melissa D Conrad, Geoffrey Otto, Patrick Kyagamba, Jackson Asiimwe, John Rek, Joaniter I Nankabirwa, Emmanuel Arinaitwe, Anne M Akol, Moses R Kamya, Sarah G Staedke, Chris Drakeley, Teun Bousema, Steve W Lindsay, Grant Dorsey, Lucy S Tusting

“…Every four weeks, we measured malaria infection (using microscopy and qPCR to detect malaria parasites), incidence of malaria, ARI and gastrointestinal illness. …”
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Impact of cardiopulmonary resuscitation on a cannot intubate, cannot oxygenate condition: a randomised crossover simulation research study of the interaction between two algorithms by Thomas Ott, Jascha Stracke, Susanna Sellin, Marc Kriege, Gerrit Toenges, Carsten Lott, Sebastian Kuhn, Kristin Engelhard

“…We propose that even experienced healthcare providers delay cricothyrotomy, a lifesaving approach, due to concurrent cardiopulmonary resuscitation in a ‘cannot intubate, cannot oxygenate’ situation.Design Due to the rare incidence and dynamics of such a situation, we conducted a randomised crossover simulation research study.Setting We collected data in our institutional simulation centre between November 2016 and November 2017.Participants We included 40 experienced staff anaesthesiologists at our tertiary university hospital centre.Intervention The participants treated two simulated patients, both requiring cricothyrotomy: one patient required cardiopulmonary resuscitation due to asphyxia, and one patient did not require cardiopulmonary resuscitation. …”
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Risk factors associated with positive QuantiFERON-TB Gold In-Tube and tuberculin skin tests results in Zambia and South Africa. by Kwame Shanaube, James Hargreaves, Katherine Fielding, Ab Schaap, Katherine-Anne Lawrence, Bernadette Hensen, Charalambos Sismanidis, Angela Menezes, Nulda Beyers, Helen Ayles, Peter Godfrey-Faussett

“…We found little evidence in our data to support our hypotheses.<h4>Conclusion</h4>QFT-GIT may not be more sensitive than the TST to detect risk factors associated with tuberculous infection. …”
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Reporting of and explanations for under-recruitment and over-recruitment in pragmatic trials: a secondary analysis of a database of primary trial reports published from 2014 to 201... by Karla Hemming, Monica Taljaard, Charles Weijer, Kelly Carroll, Stuart G Nicholls, Pascale Nevins, Yongdong Ouyang

“…In multinomial logistic regression, cluster randomisation and lower journal impact factor were significantly associated with both under-recruitment and over-recruitment, while using exclusively routinely collected data and educational/behavioural interventions were significantly associated with over-recruitment; we were unable to detect significant associations with obtaining consent, publication year, country of recruitment or public engagement.Conclusions A clear explanation for under-recruitment or over-recruitment in pragmatic trials should be provided to encourage transparency in research, and to inform recruitment to future trials with comparable designs. …”
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Widespread splicing changes in human brain development and aging by Pavel Mazin, Jieyi Xiong, Xiling Liu, Zheng Yan, Xiaoyu Zhang, Mingshuang Li, Liu He, Mehmet Somel, Yuan Yuan, Yi‐Ping Phoebe Chen, Na Li, Yuhui Hu, Ning Fu, Zhibin Ning, Rong Zeng, Hongyi Yang, Wei Chen, Mikhail Gelfand, Philipp Khaitovich

“…Identified changes were confirmed using independent human and rhesus macaque RNA‐seq data sets, exon arrays and PCR, and were detected at the protein level using mass spectrometry. …”
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In-House Validation of Four Duplex Droplet Digital PCR Assays to Quantify GM Soybean Events by Daniela Verginelli, Sara Ciuffa, Katia Spinella, Davide La Rocca, Marisa Misto, Cinzia Quarchioni, Pamela Bonini, Cristiana Fusco, Lorella Peroni, Stefania Peddis, Ugo Marchesi

“…Due to the increasing number of authorized events in the European Union, it is crucial for the official laboratories to enforce market control to detect and quantify genetically modified organisms. …”
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Whole-Genome Sequencing of Linezolid-Resistant and Linezolid-Intermediate-Susceptibility <i>Enterococcus faecalis</i> Clinical Isolates in a Mexican Tertiary Care University Hospit... by Pedro Martínez-Ayala, Leonardo Perales-Guerrero, Adolfo Gómez-Quiroz, Brenda Berenice Avila-Cardenas, Karen Gómez-Portilla, Edson Alberto Rea-Márquez, Violeta Cassandra Vera-Cuevas, Crisoforo Alejandro Gómez-Quiroz, Jaime Briseno-Ramírez, Judith Carolina De Arcos-Jiménez

“…Linezolid-non-susceptible <i>Enterococcus faecalis</i> (LNSEf) has emerged as a critical clinical concern worldwide, yet data from Latin American settings remain scarce. …”
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CT and MR in peritoneal malignancies: pearls and pitfalls at preoperative examination by Michela Polici, Federica Palmeri, Erica Golia, Emanuela Parri, Guido Gentiloni Silveri, Francesco Puglisi, Domenico De Santis, Marta Zerunian, Francesco Pucciarelli, Tiziano Polidori, Maria Ciolina, Paolo Sammartino, Andrea Laghi, Damiano Caruso

“…It is still unclear which of the two methods, CT and MRI, is superior in terms of performance, and literature data are often controversial. Thus, the purpose of this review is to provide some practical tips for CT and MRI protocols and imaging findings essential to detect and characterize peritoneal deposits in each anatomical space, and to provide an overview of the main differential diagnosis with other peritoneal conditions. …”
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Methodological approaches to survey complex ice cave environments - the case of Dobšiná (Slovakia) by Katarína Pukanská, Karol Bartoš, Juraj Gašinec, Roman Pašteka, Pavol Zahorec, Juraj Papčo, Pavel Bella, Pavel Bella, Erik Andrássy, Laura Dušeková, Diana Bobíková, Ľubomír Kseňak

“…Additional geophysical methods - microgravimetry and ground penetrating radar - revealed an average ice thickness ranging from 10 to 25 m.DiscussionThe paper not only highlights the current technological possibilities but also points out the limitations of these technologies and then sets out solutions with a proposal of technological procedures for obtaining accurate geodetic and geophysical data.…”
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Keeping Active with Texting after Stroke (KATS): a single-arm feasibility and acceptability study of a behavioural intervention to promote community-based physical activity after s... by Gozde Ozakinci, Stephan U Dombrowski, Andrew Murphy, Albert Farre, Jenna Breckenridge, Jacqui H Morris, Linda A Irvine, Keith Jenkinson

“…Findings suggest some modifications of messages and goal-setting processes are required to accommodate participants with diverse physical activity capabilities before a definitive trial. …”
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Technology Integration to Support Nurses in an “Inpatient Room of the Future”: Qualitative Analysis by Elizabeth R Stevens, Veronica Alfaro Arias, Son Luu, Katharine Lawrence, Lisa Groom

“…Analysis identified four major themes considered central to designing a technology-integrated inpatient room that enhances nursing workflow and experience: (1) the need for seamless integration of technologies advocating for a unified system that minimizes fragmented technology use and enhances efficiency; (2) the potential for technology to reduce cognitive load, alleviate mental strain, and streamline complex workflows; (3) a focus on enhancing interpersonal communication with specific emphasis on tools that facilitate clear and efficient communication among clinicians and with patients; and (4) the importance of improved staff well-being with design considerations aimed at promoting both physical and mental health for health care workers in the inpatient setting. Envisioned future solutions included enhanced patient monitoring with automated measurements and actions through computer vision and data triangulation, a smart electronic health record–integrated supply management system using computer vision to detect supply shortages and auto-delivery of needed supplies, and a personal tech smart assistant capable of real-time patient monitoring and escalation, task prioritization, and hands-free clinical documentation and communication. …”
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Performance of COVID-19 associated symptoms and temperature checking as a screening tool for SARS-CoV-2 infection. by Benjamin Demah Nuertey, Kwame Ekremet, Abdul-Rashid Haidallah, Kareem Mumuni, Joyce Addai, Rosemary Ivy E Attibu, Michael C Damah, Elvis Duorinaa, Anwar Sadat Seidu, Victor C Adongo, Richard Kujo Adatsi, Hisyovi Caedenas Suri, Abass Abdul-Karim Komei, Braimah Baba Abubakari, Enoch Weyori, Emmanuel Allegye-Cudjoe, Augustina Sylverken, Michael Owusu, Richard O Phillips

“…Some studies outside Africa have found the screening for fever using non-contact thermometers to lack good sensitivity for detecting SARS-CoV-2 infection. The aim of this study was to determine the usefulness of clinical symptoms in accurately predicting a final diagnosis of COVID-19 disease in the Ghanaian setting.…”
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Meningite neofatal: aspectos associados Neonatal meningitis: related features by Diogo C. Haussen, Lívia N. Brandalise, Fabiane A. Praetzel, André S. Malysz, Renate Mohrdieck, Marco A.F. Reichelt, Célia B. Magalhães, Sérgio P. Grossi, Ana Guardiola

“…Healthy newborns were enrolled as a Control Group (CG). Data related to pregnancy, labor and the neonate itself were collected. …”
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Antimicrobial and Metal Resistance Genes in Bacteria Isolated from Mine Water in Austria by Jakob Prochaska, Heinz Reitner, Christian Benold, Alfred Stadtschnitzer, Buyantogtokh Choijilsuren, Dmitrij Sofka, Friederike Hilbert, Cátia Pacífico

“…All <i>Pseudomonas</i> spp. carried AMR genes from the <i>mex</i> family, which encode multidrug efflux pumps. β-lactamase production encoded by <i>bla</i> genes were detected as the second most common (26%). The same AMR genes have often been detected within a particular bacterial genus. …”
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Hunting for gravity waves in non-orographic winter storms using 3+ years of regional surface air pressure network and radar observations by L. R. Allen, L. R. Allen, S. E. Yuter, S. E. Yuter, M. A. Miller, L. M. Tomkins, L. M. Tomkins

“…Reanalysis model output and operational weather observations provided environmental context for each gravity wave event. We detected 33 pressure wave events across 40 months of data; of these events, 23 were gravity waves, whereas the rest were frontal passages, outflow boundary passages, or a wake low. …”
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Chromosomal abnormalities in couples with recurrent pregnancy loss: a 16-year cross-sectional study of 4030 cases from Turkey by Sabri Aynaci, Sinem Kocagil, Efsun Tosumoglu, Ezgi Susam, Betul Kilic, Ebru Erzurumluoglu Gokalp, Oguz Cilingir, Beyhan Durak Aras, Basar Tekin, Sevilhan Artan

“…DESIGN: Retrospective, cross-sectional study SETTING: Single center, tertiary healthcare center in Turkey PATIENTS AND METHODS: This study reviewed conventional cytogenetic/molecular cytogenetic analysis data of 4030 patients (2015 couples) who visited the clinic from 2008–2024. …”
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Longitudinal monitoring of sewershed resistomes in socioeconomically diverse urban neighborhoods by Jangwoo Lee, Kevin Xiang, Emily Au, Shahrzad Sarabi, Nicole Acosta, Srijak Bhatnagar, Jennifer Van Doorn, Stefania Bertazzon, John M. Conly, Elissa Rennert-May, Johann D. D. Pitout, Bonita E. Lee, Xiaoli Pang, Christine O’Grady, Kevin Frankowski, Casey R. J. Hubert, Michael D. Parkins

“…While associations between AMR and socioeconomic-status (SES), including employment and education have been increasingly recognized in low- and middle-income settings, connections are less clear in high-income countries where SES remains an important influence on other health outcomes. …”
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Value of cardiac enzyme spectrum for the risk assessment of mortality in critically ill children: a single-centre retrospective study by Jie Wang, Xueying Chen, Junbin Huang, Cheng Shen, Huabin Wang, Lijun Gan, Chunmei Chen, Xueyun Ren

“…This study aimed to evaluate the effects of different types of cardiac enzyme spectrum within 24 hours of admission on the short-term prognosis of patients in paediatric intensive care units.Design A retrospective study.Setting A single-centre, tertiary care hospital in China, with patient data from 2010 to 2018.Participants A total of 4343 critically ill children were enrolled.Intervention None.Primary and secondary outcome measures The main outcome measure was in-hospital mortality, which was defined as death from any cause during hospitalisation. …”
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Deploying Metagenomics to Characterize Microbial Pathogens During Outbreak of Acute Febrile Illness Among Children in Tanzania by Shabani Ramadhani Mziray, George Githinji, Zaydah R. de Laurent, Peter M. Mbelele, Khadija S. Mohammed, Boaz D. Wadugu, Brian S. Grundy, Scott K. Heysell, Stellah G. Mpagama, Jaffu O. Chilongola

“…Outbreaks of infectious diseases contribute significantly to morbidity and mortality in resource-limited settings, yet the capacity to identify their etiology remains limited. …”
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Emerging antibiotic resistance in bacterial bloodstream infections: a clinical study at the Holy Family Hospital, Nkawkaw, Ghana by John Gameli Deku, Israel Bedzina, Prince Kwadade Amankwah, Lilian Kekeli Antor, Kenneth Ablordey, Madrid Alhassan, Akatwum Emmanuel Salifu, Robert Awupoli, Arnold Togiwe Luuse, Enoch Aninagyei, Innocent Afeke, Kwabena Obeng Duedu

“…The highest levels of antibiotic resistance were detected against tetracycline (94.5%), penicillin (92.3%), and chloramphenicol (90.9%). …”
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