High rate of virological failure and low rate of switching to second-line treatment among adolescents and adults living with HIV on first-line ART in Myanmar, 2005-2015. by Nang Thu Thu Kyaw, Anthony D Harries, Ajay M V Kumar, Myo Minn Oo, Khine Wut Yee Kyaw, Than Win, Thet Ko Aung, Aung Chan Min, Htun Nyunt Oo

“…Routine viral load monitoring, especially for those identified as having a higher risk of treatment failure, should be considered in this setting to detect all patients failing on first-line ART. …”
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Real-world use of tafasitamab preceding CD19-directed chimeric antigen receptor T-cell therapy for relapsed or refractory diffuse large B-cell lymphoma by Narendranath Epperla, Loretta J. Nastoupil, Bruce Feinberg, John Galvin, Prathamesh Pathak, Theresa Amoloja, Danielle Gentile, Kim Saverno

“…Four patients had complete response, 3 had partial response, and 1 had progressive disease as best response to CAR-T; 1 patient had data unavailable. This small real-world analysis demonstrated disease response to CAR-T therapy and detectable CD19 expression following tafasitamab treatment, adding to literature investigating treatment outcomes associated with sequential use of anti-CD19 therapies in patients with R/R DLBCL.…”
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Maternal Outcomes after Induction of Labor with Dinoprostone in Post-Date pregnancies by Saleha Hassan, Aasma Zubair, Seema Gul, Sandleen Javad, Amika Kumari, Hina Javed

“…This study aims to evaluate short term maternal outcomes after induction with dinoprostone in a tertiary care setting. Objective: To determine the short-term maternal outcomes (mode of delivery and postpartum hemorrhage) after induction of labor with dinoprostone in postdate pregnancies at a tertiary care hospital. …”
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Response to a peer telehealth intervention for emergency department patients presenting with opioid use disorder or unintentional overdose: a stratified interrupted time series ana... by Martha Tillson, Huiping Xu, Alan McGuire, Spencer Medcalf, Francesca L. Beaudoin, Dennis P. Watson

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Beyond illness: how chronic conditions and unhealthy behaviors impact health-related quality of life among Iranian women by Satar Rezaei

“…Public health interventions targeting these modifiable factors, especially improving sleep quality and promoting physical activity, are essential to enhance women’s well-being in Iran and similar settings.…”
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Optimising urban lighting efficiency with IoT and LoRaWAN integration in smart street lighting systems by Waheb A. Jabbar, Tan Keng Keat, Fares A. Dael, Lee Chee Hong, Yusra Farhana M. Yussof, Abdul Nasir

“…This scalable and secure solution lays the groundwork for future innovations in smart urban infrastructure, setting new benchmarks for energy-efficient city lighting.…”
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Impact of reimbursement reform on Finnish occupational health service trends in 2018–2022: an interrupted time series analysis by Mervi Viljamaa, Riitta Sauni, Mikko Korhonen, Katri Oksanen, Tiia Reho

“…We investigated the OHS trends and how the reimbursement affected them.Design A register-based study that used moving averages to visualise OHS trends in 2018–2022. To detect the impact of the reform, we used two types of interrupted time series (ITS) analyses: a linear regression model (ITS linear model) and an analysis of variance (ANOVA) lagged dependent variable model (ITS ANOVA).Setting Retrospective register data (2018–2022) of a major OHS provider in Finland.Outcome measures Time spent on OHS activities and the number of OHS activities per 1000 individuals per month. …”
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Evaluation of in-hospital management for febrile illness in Northern Tanzania before and after 2010 World Health Organization Guidelines for the treatment of malaria. by Andrew M Moon, Holly M Biggs, Matthew P Rubach, John A Crump, Venace P Maro, Wilbrod Saganda, Elizabeth A Reddy

“…<h4>Materials and methods</h4>We analyzed data from two prospective cohort studies that enrolled febrile adolescents and adults aged ≥13 years. …”
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Adverse events associated with vismodegib: insights from a real-world pharmacovigilance study using the FAERS database by Bingqing Wang, Kaidi Zhao, Ningyi Xian, Landong Ren, Jiashu Liu, Chen Tu, Dewu Zhang

“…Given its critical role in managing advanced basal cell carcinoma and the relatively high rate of treatment discontinuation, it is crucial to comprehensively understand its safety profile in real-world settings.MethodsThis study analyzed all adverse event reports that identified vismodegib as the primary suspected drug since 2012 in the FDA Adverse Event Reporting System database. …”
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Effect of tobacco control policies on the Swedish smoking quitline using intervention time-series analysis by Alessio Crippa, Anna-Karin Danielsson, Xingwu Zhou, Nicola Orsini

“…We were also able to detect a likely impact of earlier nationwide interventions.…”
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Prevalence and characterization of Carbapenem-Resistant Enterobacterales among inpatients and outpatients in Skikda, Algeria by Amina Bougouizi, Zohra Chekroud, Hamza Rahab, Ali Boumegoura, Abdelaziz Touati

“… Introduction: The spread of Carbapenemase-producing Enterobacterales (CPEs) has become a significant concern in Algeria, with limited data available on their presence in community settings. …”
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Complex immunogenicity assessment in caplacizumab-treated patients with immune-mediated thrombotic thrombocytopenic purpura who have received plasma exchange by Brendy Van Butsel, Maria Laura Sargentini-Maier, Ana Paula Marques, Yana Vandenbossche, Gabriela Marcheva, Sriya Gunawardena, Samuel Pine

“…Conclusion: A complex immunogenicity assay strategy was required to define the pre-Ab/TE ADA status of patients with iTTP treated with caplacizumab in a clinical trial setting. In addition to the wide range of pre-Abs observed, few patients had detectable TE ADAs or NAbs, neither of which affected efficacy/safety.…”
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Proportion of foetal and placental implantation abnormalities in Madagascar: A cross-sectional study of 35,919 women at public-sector primary healthcare facilities in central and s... by Franziska Krätzig, Jie Mei, Mahery Rebaliha, Zavaniarivo Rampanjato, Rinja Ranaivoson, Jenia Razafinjato, Jan-Walter De Neve, Mara Anna Franke, Nadine Muller, Julius Valentin Emmrich

“…In contrast to current WHO recommendations, pregnant women, particularly those from rural, resource-constrained settings attend obstetric ultrasound screenings most commonly during their third trimester of pregnancy.…”
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Identification and outcomes of acute kidney disease in patients presenting in Bolivia, Brazil, South Africa, and Nepal. by Rhys D R Evans, Sanjib K Sharma, Rolando Claure-Del Granado, Brett Cullis, Emmanuel A Burdmann, Fos Franca, Junio Aguiar, Martyn Fredlund, Kelly Hendricks, Maria F Iturricha-Caceres, Mamit Rai, Bhupendra Shah, Shyam Kafle, David C Harris, Mike V Rocco

“…High rates of persistent kidney disease and mortality after discharge highlight the importance of AKD follow-up in low-resource settings.…”
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Whole-genome sequencing of non-typeable Haemophilus influenzae isolated from a tertiary care hospital in Surabaya, Indonesia by Made Ananda Krisna, Lindawati Alimsardjono, Korrie Salsabila, Naritha Vermasari, Wa Ode Dwi Daningrat, Kuntaman Kuntaman, Odile Barbara Harrison, Martin Christopher James Maiden, Dodi Safari

“…Reports on circulating H. influenzae causing invasive disease in lower-middle income settings, including Indonesia, are lacking. This study describes the serotype distributions and whole-genome sequence (WGS) data of H. influenzae isolated from hospitalized patients at Soetomo Hospital, Surabaya, Indonesia. …”
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Species Identification in Malaise Trap Samples by DNA Barcoding Based on NGS Technologies and a Scoring Matrix. by Jérôme Morinière, Bruno Cancian de Araujo, Athena Wai Lam, Axel Hausmann, Michael Balke, Stefan Schmidt, Lars Hendrich, Dieter Doczkal, Berthold Fartmann, Samuel Arvidsson, Gerhard Haszprunar

“…These promising results indicate that a fast, efficient and reliable analysis of next generation data from malaise trap samples can be achieved using this pipeline.…”
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Bringing anatomy to life: the role of clinical ultrasound in undergraduate medical education – a systematic review by Mathilde Brunel, Valentin Sebastian Schäfer, Florian Recker

“…Abstract Background The implementation of ultrasound as point-of-care technique within the medical education has been broadly studied to understand its applicability in clinical settings. More research has been conducted to specifically understand the use of clinical ultrasound in the medical curriculum to learn anatomy. …”
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Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. by Chenxing Liu, Myoung Keun Lee, Sahin Naqvi, Hanne Hoskens, Dongjing Liu, Julie D White, Karlijne Indencleef, Harold Matthews, Ryan J Eller, Jiarui Li, Jaaved Mohammed, Tomek Swigut, Stephen Richmond, Mange Manyama, Benedikt Hallgrímsson, Richard A Spritz, Eleanor Feingold, Mary L Marazita, Joanna Wysocka, Susan Walsh, Mark D Shriver, Peter Claes, Seth M Weinberg, John R Shaffer

“…Most of these loci have been detected in Europeans, with few studies focusing on other ancestral groups. …”
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Deep learning-based automated tool for diagnosing diabetic peripheral neuropathy by Qincheng Qiao, Juan Cao, Wen Xue, Jin Qian, Chuan Wang, Qi Pan, Bin Lu, Qian Xiong, Li Chen, Xinguo Hou

“…Corneal confocal microscopy (CCM) can non-invasively detect changes in corneal nerve fibers (CNFs), making it a potential tool for the early diagnosis of DPN. …”
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A multimodal approach for enhanced disease management in cauliflower crops: integration of spectral sensors, machine learning models and targeted spraying technology by Rohit ANAND, Roaf Ahmad PARRAY, Indra MANI, Tapan Kumar KHURA, Harilal KUSHWAHA, Brij Bihari SHARMA, Susheel SARKAR, Samarth GODARA, Shideh MOJERLOU, Hasan MIRZAKHANINAFCHI

“…For non-destructive disease assessment, a spectral sensor was used to collect spectral information from diseased and healthy cauliflower parts. The spectral data sets were analyzed using decision tree and support vector machine (SVM) algorithms to identify the most accurate model for distinguishing diseased and healthy plants. …”
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