Accelerometery as a measure of modifiable physical activity in high-risk elderly preoperative patients: a prospective observational pilot study by Ari Ercole, Simon J Griffin, Joanne G Outtrim, Lisa Grimes

“…Objectives To use wrist-worn accelerometers (Axivity AX3) to establish normative physical activity (PA) and acceptability data for the high-risk elderly preoperative population, to assess whether PA could be modified by a prehabilitation intervention as part of routine care, to assess any correlation between accelerometer-measured PA and self-reported PA and to assess the acceptability of wearing wrist-worn accelerometers in this population.Study design Prospective, observational, pilot study.Setting Single National Health Service Hospital.Participants Frail patients≥65 years awaiting major surgery referred to a multidisciplinary preoperative clinic at which they received a routine intervention aimed at improving their PA. 35 patients were recruited. …”
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Body weight trajectories from midlife are associated with cognitive decline in advanced age by Chiara Ceolin, Federica Prinelli, Caterina Trevisan, Adele Ravelli, Silvia Conti, Lorraine Brennan, Lisette C. P. G. M. de Groot, Claire T. McEvoy, Stefania Maggi, Giuseppe Sergi, Marianna Noale, the PROMED-COG Consortium

“…This retrospective study analyzed harmonized data from two population-based longitudinal studies, the Progetto Veneto Anziani and the Italian Longitudinal Study of Aging, encompassing baseline and two follow-up assessments over 9 years. …”
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Greater sage‐grouse male lek counts relative to a wind energy development by Chad W. Lebeau, Jeffrey L. Beck, Gregory D. Johnson, Ryan M. Nielson, Matthew J. Holloran, Kenneth G. Gerow, Trent L. McDonald

“…Use of a posteriori power analysis estimated similar data sets would have 80% probability of detecting a 28% decrease in the rate of decline of lek counts at treatment leks relative to control leks after development. …”
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Infection prevention and control measures during the COVID-19 pandemic and airborne tuberculosis transmission during primary care visits in South Africa by Nicolas Banholzer, Keren Middelkoop, Remo Schmutz, Juane Leukes, Kathrin Zürcher, Matthias Egger, Robin Wood, Lukas Fenner

“…Airborne Mtb DNA was detected in both periods. Conclusion: Pandemic-related IPC measures to control COVID-19 transmission were rigorously implemented and likely reduced transmission of airborne respiratory infections, supporting their continued implementation in healthcare settings postpandemic.…”
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Bidirectional two-sample Mendelian randomization study of atrial fibrillation and breast cancer by Fan Ding, Fan Ding, Chen Chen, Yuling Wang, Yuling Wang, Tingting Zhu, Linke Jiao, Linke Jiao, Zihuan Shen, Zihuan Shen, Zhiwei Zhang, Lifei Lv, Xiangning Cui, Yingdong Lu

“…In this study, bidirectional two-sample Mendelian randomization (MR) combined with meta-analysis was used to evaluate the causal association between BC and AF.MethodsBased on the Genome-Wide Association Studies (GWAS) summary data sets, the Inverse variance weighted (IVW) method was used as the main method, the weighted median method and MR-Egger method were used for Bidirectional Two-Sample Mendelian Randomization, and the Egger intercept test was used to detect horizontal pleiotropy. …”
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A comprehensive, population level evaluation of previously reported drug triggers of pemphigus highlights immunomodulatory capacity as a common characteristic by Justin Baroukhian, Kristina Seiffert-Sinha, Animesh A. Sinha

“…Associations for other previously reported drugs (25/36) were not detected.Conclusions and relevanceThis study represents a comprehensive evaluation of suspected drug triggers of pemphigus using real-world data. …”
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Intravenous lidocaine for gut function recovery in colonic surgery: a health economic evaluation of the ALLEGRO randomised clinical trial by John Norrie, Graeme Maclennan, Lorna Aucott, Karen Innes, Andrew Stoddart, Seonaidh Cotton, Hugh Paterson, Doug Speake, Robert Arnott, Thenmalar Vadiveloo, Marek Atter, Angie Balfour, Zoe Batham, Irwin Foo, Susan Nimmo

“…Objectives To compare costs, health outcomes and cost-effectiveness of using intravenous lidocaine (bolus given at induction of anaesthesia, followed by infusion for 6–12 hours) during colorectal surgery to improve the return of gastrointestinal function.Design Within-trial planned analysis of data from a randomised controlled trial using an intention-to-treat approach.Setting 27 hospitals from across the UK.Participants 557 patients aged 25–91 having minimally invasive elective colorectal resection.Intervention A 1:1 randomisation between intravenous lidocaine and placebo, minimised for age (<50 years, 50–74 years, ≥75 years), gender, and trial centre.Primary outcome measures Mean differences between trial arms in 30-day and 90-day quality-adjusted life-years (QALYs) and 30-day total National Health Service costs, as well as the 30-day incremental cost-effectiveness ratio.Results Compliance and data quality were high. …”
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Venous Thromboembolism Prophylaxis in Intensive Care Units (Review) by L. V. Popova, T. B. Kondratieva, M. Z. Kanevskaya, T. L. Aleinikova, E. S. Zykova, А. V. Krivova, A. M. Kuznetsov

“…The exclusion criteria included data of low informative value or disproven data.The review discusses VTE relevance, risk factors for its development, selection and scope of preventive care depending on the risk of thrombosis and hemorrhage, patient management in different clinical settings (impaired renal function, thrombocytopenia, heparin-induced thrombocytopenia, liver dysfunction, indications for installation of vena cava filter).In the world literature, however, there is yet no consensus on the matter under discussion that would have been based on meta-analyses or large randomized studies. …”
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Wide-field electromagnetic method for deep hot dry rock fracturing monitoring: penetrating thick low-resistivity overburden by Shiyin Gao, Shiyin Gao, Wubing Deng, Juncheng Wang, Juncheng Wang, Juncheng Wang, Juncheng Wang, Mingzuan Xu, Mingzuan Xu

“…Key acquisition parameters were optimized via forward modeling, including transmitter-receiver distance (*r* = 15 km), current (I = 130 A), and electrode spacing (AB = 3,000 m, MN = 100 m).ResultsField data revealed distinct resistivity reduction zones (1,000→25 Ωm) spatially correlated with active fracturing wells, demonstrating WFEM’s ability to detect fluid-induced anomalies (Δρ up to 30%). …”
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Sensor-Derived Measures of Motor and Cognitive Functions in People With Multiple Sclerosis Using Unsupervised Smartphone-Based Assessments: Proof-of-Concept Study by Matthew Scaramozza, Aurélie Ruet, Patrizia A Chiesa, Laïtissia Ahamada, Emmanuel Bartholomé, Loïc Carment, Julie Charre-Morin, Gautier Cosne, Léa Diouf, Christine C Guo, Adrien Juraver, Christoph M Kanzler, Angelos Karatsidis, Claudia Mazzà, Joaquin Penalver-Andres, Marta Ruiz, Aurore Saubusse, Gabrielle Simoneau, Alf Scotland, Zhaonan Sun, Minao Tang, Johan van Beek, Lauren Zajac, Shibeshih Belachew, Bruno Brochet, Nolan Campbell

“…All selected SDMs demonstrated moderate-to-good reliability in remote settings (intraclass correlation coefficient 0.5-0.85; minimal detectable change at 95% CI 19%-35%). …”
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Combined health risks of cigarette smoking and low levels of physical activity: a prospective cohort study in England with 12-year follow-up by Andrew Steptoe, Sarah E Jackson, Lion Shahab, Jamie Brown, Lee Smith, Michael Ussher

“…While additive effects were evident, tests of multiplicative interactions revealed no evidence of large synergistic effects of smoking and low physical activity (Bayes factor range 0.04–0.61), although data were insensitive to detect smaller effects.Conclusions Among older adults in England, there was no evidence of large synergistic effects of smoking and low levels of physical activity on risk of developing chronic disease or depressive symptoms over 12 years. …”
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Analysing Open-source Images to Assess Face Mask Usage for Epidemiological Studies by Dr Hang Ding, Mrs Ashley Quigley, Professor Raina MacIntyre

“…Research during the COVID-19 pandemic has sought to manually quantify mask use in mass gatherings and public settings. Open-source images of mass gatherings or other large events on news and social media contain valuable information about face mask usage. …”
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Predicting subjective sleepiness during auditory cognitive testing using voice signaling analysis by Tue T. Te, Mary Regina Boland, Sara Ghadimi, Joseph M. Dzierzewski, Cathy Alessi, Jennifer L. Martin, Sarah Kremen, Alex A. T. Bui, Arash Naeim, Constance H. Fung

“…Abstract Background To determine whether objective markers of sleepiness can be collected passively using voice data to detect sleepiness in individuals undergoing testing in situations where sleepiness is not the focal point of assessment. …”
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Impact of the COVID-19 pandemic on prescription drug use and costs in British Columbia: a retrospective interrupted time series study by Kimberlyn McGrail, Sabrina T Wong, Mina Tadrous, Lucy Cheng, Michael Law, Seraphine Zeitouny

“…Objectives To assess the impact of the COVID-19 pandemic on prescription drug use and costs.Design Interrupted time series analysis of comprehensive administrative health data linkages in British Columbia, Canada, from 1 January 2018 to 28 March 2021.Setting Retrospective population-based analysis of all prescription drugs dispensed in community pharmacies and outpatient hospital pharmacies and irrespective of the drug insurance payer.Participants Between 4.30 and 4.37 million individuals (52% women) actively registered with the publicly funded medical services plan.Intervention COVID-19 pandemic and associated mitigation measures.Main outcome measures Weekly dispensing rates and costs, both overall and stratified by therapeutic groups and pharmacological subgroups, before and after the declaration of the public health emergency related to the COVID-19 pandemic. …”
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Farm-scale mapping of compost and digestate spreadings from Sentinel-2 and Sentinel-1 by Maxence Dodin, Florent Levavasseur, Antoine Savoie, Lucie Martin, Emmanuelle Vaudour

“…Within-field reference areas were delineated based on both the observed amendment practices, crops and soil map and randomly selected with replacement to train/ validate SVM with several iterations. Various feature sets composed of bands, signals and specific spectral indices from either Sentinel-2 and/or Sentinel-1 data served to compute SVM in a bootstrapping approach in order to produce a series of map results, to assess the final mode class and the uncertainty of map results. …”
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Diarrhea treatment center (DTC) based diarrheal disease surveillance in settlements in the wake of the mass influx of forcibly displaced Myanmar national (FDMN) in Cox's Bazar, Ban... by Abu S G Faruque, Azharul Islam Khan, S M Rafiqul Islam, Baitun Nahar, M Nasif Hossain, Yulia Widiati, A S M Mainul Hasan, Mukeshkumar Prajapati, Minjoon Kim, Maya Vandenent, Tahmeed Ahmed

“…<h4>Conclusion</h4>No diarrhea outbreak was detected, but preparedness for surges and response readiness are warranted in this emergency and crisis setting.…”
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Prevalence of dry eye disease among operating room nurses in tertiary care hospital: Cross-sectional survey by Natwarlal Patidar, Talagatoti David Ratna Paul, Ravi Gaur, Shoma Mukharjee, Nitika Thakur, R Sreeraja Kumar

“…Significant DED was detected in 43.5% (50/115) of nursing officers working in operating room. …”
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Increasing the use of home medication lists in an outpatient neurorehabilitation clinic by Christine Soong, Meiqi Guo, Alan Tam, Ayan Dey, Beth Fraser, Margaret Podalak, Mark Bayley, Alexander Lo

“…Medication reconciliation in ambulatory care settings helps prevent adverse drug events. Patient involvement in the process is crucial, as clinicians must verify the reported medication history with other sources such as home medication lists or brown-bagged home medications provided by patients. …”
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Examiner experience moderates reliability of human lower extremity muscle ultrasound measurement – a double blinded measurement error study by Konstantin Warneke, Stanislav D. Siegel, Jonas Drabow, Lars H. Lohmann, Daniel Jochum, Sandro R. Freitas, José Afonso, Andreas Konrad

“…Abstract Structural muscle properties are critical in health and athletic settings, with magnetic resonance imaging considered the gold standard assessment procedure under static conditions due to its reliability and objectivity. …”
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Seven-year evaluation of Stenotrophomonas maltophilia bacteremia in a university-affiliated hospital by Aysegul I Sezen, Yusuf E Ozdemir, Zuhal Yeşilbağ, Deniz Borcak, Esra Canbolat Ünlü, Fatma Bayrak Erdem, Zeynep Çizmeci, Enes Topcu, Kadriye Kart Yasar

“…These bacteria can be isolated from healthcare settings, possibly resulting in bacterial colonization of medical devices, which cause nosocomial infections. …”
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