Impact of non-invasive oxygen reserve index versus standard SpO2 monitoring on peripheral oxygen saturation during endotracheal intubation in the intensive care unit: Protocol for... by Hugo Hille, Aurélie Le Thuaut, Pierre Asfar, Quentin Quelven, Emmanuelle Mercier, Anthony Le Meur, Jean-Pierre Quenot, Virginie Lemiale, Grégoire Muller, Martin Cour, Alexis Ferré, Asael Berge, Anaïs Curtiaud, Maxime Touron, Gaetan Plantefeve, Jean-Charles Chakarian, Jean-Damien Ricard, Gwenhael Colin, Arthur Orieux, Patrick Girardie, Mathieu Jozwiak, Manon Rouaud, Camille Juhel, Jean Reignier, Jean-Baptiste Lascarrou, CRICS-TRIGGERSEP Network

“…Assuming a 10% standard deviation for the lowest SpO2 value in the control group, no missing data, and crossover of 5% of patients, with the bilateral alpha risk set at 0.05, including 950 patients will provide 85% power for detecting a 2% between-group absolute difference in the lowest SpO2 value. …”
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Peculiar morphology of Asgard archaeal cells close to the prokaryote-eukaryote boundary by Burak Avcı, Kassiani Panagiotou, Mads Albertsen, Thijs J. G. Ettema, Andreas Schramm, Kasper Urup Kjeldsen

“…The remarkable size and morphology of the detected Hodarchaeales-related cells suggest a potential for complex eukaryote-like cellular architecture in these as-yet-uncultivated Asgard archaea, which could represent a key transitional stage in eukaryogenesis.IMPORTANCEAsgard archaea played a pivotal role in the evolution of complex cellular life, as recent data revealed their close relationship to eukaryotes in the Tree of Life and a genetic repertoire suggesting intricate cellular organization. …”
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Transiently elevated expression of different forms of brain-derived neurotrophic factor in the neonatal medial prefrontal cortex affected anxiety and depressive-like behaviors in a... by Dmitriy Lanshakov, Elizaveta Shaburova, Ekaterina Sukhareva, Veta Bulygina, Uliana Drozd, Irina Larionova, Tatiana Gerashchenko, Tatiana Shnaider, Evgeny V. Denisov, Tatyana Kalinina

“…LV-pBDNF mut caused a complete opposite set of transcriptional changes in the PSC compared to LV-BDNF. …”
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Jazan Rainfall’s Seasonal Shift in Saudi Arabia: Evidence of a Changing Regional Climate by M. Nazrul Islam, Arjan O. Zamreeq, Muhammad Ismail, Turki M. A. Habeebullah, Ayman S. Ghulam

“…Notably, August 2024 marked a record-breaking rainfall of 414.8 mm, surpassing the previous high of 157.5 mm set in October 1997. These data show clear evidence of the changing climate in the region. …”
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Treatment of erectile dysfunction in patients after kidney transplantation depending on type of vascular anastomosis: results of short-term follow up study by A. R. Zagitov, F. N. Mukhamedyanov, A. A. Izmailov, L. M. Kutliyarov, V. N. Pavlov

“…Significant erectile function disorders were detected in 26 (68.4%) patients of group I, and in 31 (73.9%) patients of group II, according to data from the IIEF-5 questionnaire. …”
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Emerging Diagnostic Approaches for Musculoskeletal Disorders: Advances in Imaging, Biomarkers, and Clinical Assessment by Rahul Kumar, Kiran Marla, Kyle Sporn, Phani Paladugu, Akshay Khanna, Chirag Gowda, Alex Ngo, Ethan Waisberg, Ram Jagadeesan, Alireza Tavakkoli

“…While existing reviews typically focus on advances within a single modality or for specific MSK conditions, this paper integrates a broad spectrum of developments to highlight how use of multimodal diagnostic strategies in combination can improve disease detection, stratification, and clinical decision-making in real-world settings. …”
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Morphological Arrhythmia Classification Based on Inter-Patient and Two Leads ECG Using Machine Learning by Hasballah Zakaria, Elsa Sari Hayunah Nurdiniyah, Astri Maria Kurniawati, Dziban Naufal, Nana Sutisna

“…This work also details the method covering data set preparation, algorithm and design parameters exploration for pre-processing ECG signals, features extraction and selection, and hyper parameter tuning for employed machine learning methods. …”
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Navigating Ethical Dilemmas Of Generative AI In Medical Writing by Qurrat Ulain Hamdan, Waleed Umar, Mahnoor Hasan

“…To safeguard their sensitive data, users often have to go on a deep dive into the “settings” of these tools. …”
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HEROIC: a 5-year observational cohort study aimed at identifying novel factors that drive diabetic kidney disease: rationale and study protocol by Neil Ashman, Ben Caplin, David Wheeler, Tahseen Ahmad Chowdhury, Kieran Mccafferty, Sinead Knight, Paul Hockings, Stanley L Fan, Johannes Hulthe, Robert Kleta, Vasilios Papastefanou, Hemal Mehta, Alan Salama, Sinela Hadzovic, Lisa Jarl, Robert Unwin, Benjamin Challis, Anna K Sundgren, Muhammad Magdi Yaqoob

“…Demographic, clinical and laboratory data will be collected and assessed annually for 5 years. …”
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PD-1/PD-L1 and coronary heart disease: a mendelian randomization study by Liangjia Zeng, Liangjia Zeng, Liangjia Zeng, Yinglan Liang, Yinglan Liang, Ruoyun Zhou, Ruoyun Zhou, Wenting Yang, Wenting Yang, Kexin Chen, Kexin Chen, Baixin He, Baixin He, Yuqing Qiu, Yuqing Qiu, Linglong Liu, Linglong Liu, Deyang Zhou, Deyang Zhou, Zhaolin Xiao, Zhaolin Xiao, Haowen Liang, Haowen Liang, Binghua Zhang, Binghua Zhang, Renyu Li, Renyu Li, Lihong Yu, Min Yi, Xiaozhen Lin

“…Thus, we conducted this mendelian randomization analysis (MR) to estimate the causal relationship between PD-1/PD-L1 and 5 specific CHDs (chronic ischemic heart disease, acute myocardial infarction, angina pectoris, coronary atherosclerosis, and unstable angina pectoris), complemented by gene set enrichment analysis (GSEA) for further validation.MethodsPublicly available summary-level data were attained from the UK Biobank with genetic instruments obtained from the largest available, nonoverlapping genome-wide association studies (GWAS). …”
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Study of Clinical Characteristics of AIDS Patients With Opportunistic Infections: Findings From Cut Mutia General Hospital by Alfi Syahri, Tintin Sukartini Sukartini, Erna Dwi Wahyuni, Sriyono Sriyono, Hakim Zulkarnain, Wikan Purwihantoro Sudarmaji, Domingos Soares, Mawaddah Fitria, Eti Rahmawati

“…In resource-limited settings such as Aceh, Indonesia, the burden of OIs significantly impacts the management and outcomes of HIV/AIDS patients. …”
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Introducing HeliEns: A Novel Hybrid Ensemble Learning Algorithm for Early Diagnosis of <i>Helicobacter pylori</i> Infection by Sultan Noman Qasem

“…The development of HeliEns involved rigorous data preprocessing steps, including data cleaning, encoding of categorical variables, and feature scaling, to ensure the dataset’s suitability for quantum machine learning algorithms. …”
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Association Between Social Distancing Compliance and Public Place Crowding During the COVID-19 Pandemic: Cross-Sectional Observational Study Using Computer Vision to Analyze Survei... by Lasse Suonperä Liebst, Wim Bernasco, Peter Ejbye-Ernst, Nigel van Herwijnen, Thomas van der Veen, Dennis Koelma, Cees G M Snoek, Marie Rosenkrantz Lindegaard

“…Furthermore, our results highlight the need for scholars and public health agencies to consider the situational factors influencing social distancing violations, especially those related to crowding in public settings.…”
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CLINICAL PROFILE OF PATIENTS WITH EARLY AXIAL SPONDYLOARTHRITIS (RUSSIAN COHORT OF PATIENTS) by E. E. Gubar', A. G. Bochkova, T. V. Dubinina, A. B. Dyomina, O. A. Rumyantseva, M. M. Urumova, S. V. Shubin, A. A. Godzenko, A. V. Smirnov, E. Yu. Tyukhova, S. I. Glukhova, Sh. F. Erdes

“…X-ray revealed definite SI in 49.3% of patients («classic» AS). According to MRI data, 30.1% of patients with active SI and without structural changes of sacroiliac joints had pre-radiological stage of AS (by Russian version of modified New York criteria). 74.0% of patients fulfilled both sets of ASAS criteria for axSpA, 5.5% – met only I criteria set, whereas 20.5% – only II criteria set. …”
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Applications of point-of-care ultrasound on the heart and great vessels in pediatric emergency departments: a systematic scoping review by Michael Zon, Si-Cheng Dai, Mansi Mehta, Jessica Zon

“…Purpose Point-of-care ultrasound (POCUS) has become a vital rapid diagnostic tool in emergency departments (EDs) for evaluating the adult heart and great vessels, notably in detecting conditions like aortic dissections. Compared to the adult applications, its use in pediatric emergency settings, however, has been less clearly defined. …”
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Prevalence and characterization of extended spectrum beta-lactamase-producing Enterobacter cloacae strains in Algeria by Sabrina Nedjai, Abouddihaj Barguigua, Nassima Djahmi, Loubna Jamali, Khalid Zerouali, Mazouz Dekhil, Mohammed Timinouni

“…Various risk factors associated with the occurrence of ESBL-producing E. cloacae were detected. Conclusions: A higher frequency of ESBL-producing isolates and a diversity of β-lactamases were detected among ESBL-producing E. cloacae; these resulted from an epidemic clonal dissemination and high transference of ESBL genes between bacteria in hospital settings. …”
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Accuracy of abbreviated breast magnetic resonance imaging protocols for primary tumor and post-treatment evaluation by Lina Choridah, Kardinah Kardinah, Vincent Laiman, Zannuba Arifah Noor, Putri Noviantika Laskarsantri, Rozan Muhammad Irfan, Sariningsih Hikmawati

“…Abstract Background Prompt and accurate detection of breast lesions is essential to improve patient outcomes, particularly in settings with limited access to extensive imaging. …”
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Weak-lensing Mass Reconstruction of Galaxy Clusters with a Convolutional Neural Network. II. Application to Next-generation Wide-field Surveys by Sangjun Cha, M. James Jee, Sungwook E. Hong, Sangnam Park, Dongsu Bak, Taehwan Kim

“…Rubin Observatory, we generated training data sets of mock shear catalogs with a source density of 33 arcmin ^−2 from cosmological simulation ray-tracing data. …”
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Opportunistic Diagnostics of Dental Implants in Routine Clinical Photon-Counting CT Acquisitions by Maurice Ruetters, Holger Gehrig, Christian Mertens, Sinan Sen, Ti-Sun Kim, Heinz-Peter Schlemmer, Christian H. Ziener, Stefan Schoenberg, Matthias Froelich, Marc Kachelrieß, Stefan Sawall

“…With growing digitalization and cross-disciplinary integration, using PCCT data from other medical fields is becoming increasingly relevant. …”
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Research on Bacteria Diversity of Marine Ranch in Zhuhai Wailingding Based on eDNA Technology by Nengwei ZANG, Aiyi ZHU, Pimao CHEN, Huarong YUAN, Honghui ZHANG, Wendi WEI

“…【Result】A total of 30 species of microorganisms in Zhuhai Wailingding Marine Ranch were detected by eDNA technology, and 5 phyla, 7 classes, 14 orders, 19 families and 26 genera were identified, and a total of 779 706 Operational Taxonomic Units (OTUS) were detected. …”
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