Weak Acids as Endogenous Inhibitors of the Proton-Activated Chloride Channel by Inês C. A. Pombeiro Stein, Maren Schulz, Daniel Rudolf, Christine Herzog, Frank Echtermeyer, Nils Kriedemann, Robert Zweigerdt, Andreas Leffler

“…To conclude, weak acids inhibit PAC via an extracellular mechanism involving Arg93. These data warrant further investigations into the regulation of the PAC channel by endogenous weak acids.…”
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Towards climate-resilient conservation: Integrating genetics and environmental factors in determining adaptive units of a xeric shrub by Yong-Zhi Yang, Pei-Wei Sun, Chong-Yi Ke, Min-Xin Luo, Jui-Tse Chang, Chien-Ti Chao, Run-Hong Gao, Pei-Chun Liao

“…We analyzed RAD-seq data from 217 samples across 19 populations, integrating ecological niche modeling (ENM) and GradientForest (GF) to pinpoint adaptive genetic variations. …”
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Spatiotemporal analysis and threshold modeling of rainfall-induced geological disasters in Anhui Province by Bo Wang, Bo Wang, Jie Liu, Gaoping Liu, Pan Gao, Pan Gao, Sumera Anwar, Zhaoye Wu, Muxin Li, Muxin Li, Dayao Li, Dayao Li

“…Results show: (1) Landslides and collapses are the main types, mostly occurring in high altitude areas like the Dabie and southern Anhui Mountains, and are concentrated in the rainy season of June - July each year; (2) Rainfall is the main inducer, with both single heavy rainfall processes and sustained rainfall influencing geological disaster occurrence, mostly through their combined effect; (3) Effective rainfall is significantly correlated with the day of and previous 8 days rainfall. …”
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Architecture for pavement pothole evaluation using deep learning, machine vision, and fuzzy logic by Mario Roman-Garay, Hector Rodriguez-Rangel, Carlos Beltran Hernandez-Beltran, Peter Lepej, José Eleazar Arreygue-Rocha, Luis Alberto Morales-Rosales

“…Traditional detection methods, like manual inspections, are labor-intensive, costly, and prone to errors. …”
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Patient and provider perceptions of the impact of COVID-19 on tuberculosis healthcare access and delivery: an interpretive description study of the complexities of a pandemic withi... by Michael K Stickland, Paul E Ronksley, Maxi Miciak, Kadija Perreault, Courtney Heffernan, Douglas P Gross, Grace Y Lam, Jason Weatherald, Giovanni Ferrara, Katelyn Brehon, Pam Hung, Angela Lau, Rachel Lim

“…Interviews were conducted virtually and confidentially transcribed verbatim. Data generation and analysis occurred concurrently. …”
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Unveiling the Dynamics and Genesis of Small-scale Fine-structure Loops in the Lower Solar Atmosphere by Annu Bura, Tanmoy Samanta, Alphonse C. Sterling, Yajie Chen, Jayant Joshi, Vasyl Yurchyshyn, Ronald L. Moore

“…In this study, we conducted a comprehensive analysis of two small loops utilizing data from the Interface Region Imaging Spectrograph (IRIS), the Goode Solar Telescope (GST) at Big Bear Solar Observatory, and the Atmospheric Imaging Assembly and the Helioseismic Magnetic Imager on board the Solar Dynamics Observatory, aiming to elucidate the underlying process behind their formation. …”
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Enhancing Anomaly Detection in Attributed Networks Using Proximity Preservation and Advanced Embedding Techniques by Wasim Khan, Mohammad Ishrat, Mohammad Nadeem Ahmed, Shafiqul Abidin, Mohammad Husain, Mohd Izhar, Abu Taha Zamani, Mohammad Rashid Hussain, Arshad Ali

“…Self-supervised tasks like attribute masking and edge prediction further enhance the GCAE’s ability to capture the graph’s structure. …”
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Barriers and facilitators to the implementation of palliative care services at five tertiary hospitals in Nigeria: a qualitative formative study by Chisom Obiezu-Umeh, Ann Abiola Ogbenna, Lyra S. Johnson, Matthew T. Caputo, Lisa R. Hirschhorn, Tonia Chinyelu Onyeka, Akinwale Mukaila Oyegbade, Geraldine Ugochinyere Ndukwu, Israel Kayode Kolawole, Ayilara Saheed Alao, Gracia Ker Eke, Nadia Adjoa Sam-Agudu, Ashti Doobay-Persaud

“…Guided by the Consolidated Framework for Implementation Research (CFIR), qualitative data were analyzed using the framework approach. …”
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A secondary analysis of cortical atrophy and plasma amyloid β patterns in older patients with cognitive frailty undergoing elective surgery by Rudolf Mörgeli, Friedrich Borchers, Insa Feinkohl, Sophie K. Piper, Tobias Pischon, Arjen J.C. Slooter, Claudia Spies, Janine Wiebach, Georg Winterer, Norman Zacharias, Florian Lammers-Lietz

“…Plasma amyloid β42/β40-ratios were significantly lower in patients with frailty and cognitive frailty, suggesting that (pre-)frailty in general, rather than cognitive frailty specifically, is associated with AD-like changes. Hence, AD-related pathology seems to be associated with cognitive frailty, but the available data is not sufficient to indicate shared pathomechanisms between AD and cognitive frailty. …”
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Presenting the model of social entrepreneurship in the development of rural tourism in the target villages of Gilan province by Fatemeh Doozandeh Ziabari, hamed fallah tafti, Mir Mohammad Asadi, Mahdi Basouli

“…The obtained results showed that the nine main factors affecting the formation of higher education tourism in Iran in order of influence are: dynamic political exchanges with the world at the national level, the existence of macro-national policies in the field of academic interaction, facilitating the process of acceptance in political and administrative dimensions, the existence of economic and technical infrastructures for foreign students, the international language level of faculty members and staff as well as the structure of dynamic and accepting higher education, the existence of a sense of security in social, security and political dimensions for foreign students, and branding factors of universities and introducing historical, cultural and religious attractions to the world.Ratten (2020) in a research comprehensively examined researches in the field of entrepreneurship in tourism and it is noted that it focused on lifestyle and sustainable forms of tourism entrepreneurship without considering emerging technologies and other forms of entrepreneurship like digital and social.Research methodologyThe research method is qualitative and applicable. …”
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Park7 deletion leads to sex-specific transcriptome changes involving NRF2-CYP1B1 axis in mouse midbrain astrocytes by Sergio Helgueta, Tony Heurtaux, Alessia Sciortino, Yujuan Gui, Jochen Ohnmacht, Pauline Mencke, Ibrahim Boussaad, Rashi Halder, Pierre Garcia, Rejko Krüger, Michel Mittelbronn, Manuel Buttini, Thomas Sauter, Lasse Sinkkonen

“…The affected genes are involved in processes like focal adhesion, extracellular matrix interaction, and epithelial-to-mesenchymal transition (EMT), and enriched for primary target genes of NRF2. …”
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A review of vortex water turbine design for sustainable energy generation (principles, optimization, and validation) by Zamzami, Akhyar Akhyar, Sarwo Edhy Sofyan, Suriadi, Khairil

“…The article explores advancements in intelligent water vortex turbine design, incorporating cutting-edge manufacturing methods like Computer-Aided Design (CAD) modeling, simulation, and 3D printing. …”
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Location of capture sufficiently characterises lifetime growth trajectories in a highly mobile fish by Joshua S. Barrow, Jian D. L. Yen, John D. Koehn, Brenton Zampatti, Ben Fanson, Jason D. Thiem, Zeb Tonkin, Wayne M. Koster, Gavin L. Butler, Arron Strawbridge, Steven G. Brooks, Ryan Woods, John R. Morrongiello

“…We suggest that, for highly mobile fish like golden perch and in the absence of fine, ‘within reach’ scale biological data, coarser ‘reach-scale’ environmental variation may adequately describe individual growth trajectories.…”
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Prevalence and determinants of HIV testing-seeking behaviors among women of reproductive age in Tanzania: analysis of the 2022 Demographic and health survey by Jackson Micheal Asingwire, Isaac isiko, Kuli Faith Rombe, Aaron Mwesigwa, Emmanuel Asher Ikwara, Haron Olot, Lenz Nwachinemere Okoro, Manankong Jane Precious Izunwanne, Blessing Onyinyechi Agunwa, Abdul Aziiz Bwana, William Yiga Kalemba, Ebuka Louis Anyamene

“…The study utilized individual recodes (IR) files where data was collected using the Women’s Questionnaire to analyze factors influencing HIV testing behavior among women, Descriptive analysis, and bivariate and multivariate logistic regressions were performed and all the data were processed and analyzed using STATA version 17 at 95% CI and significance level P < 0.05. …”
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A bibliometric study on Sordariales fungi covering genetic diversity, ecological interactions and biotechnological applications by N.F. Wulandari, A.R. Syam, L. Alhamd, B. Gunadi, Yosmaniar , E. Widjaja, B.N. Utomo, S. Wahyuwardani, R. Widiastuti, T. Kadarini, D. Safar

“…Future research should expand data sources and explore molecular mechanisms, as Sordariales fungi are vital for ecological processes and innovative biotechnological applications.…”
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Small-sided games for technical and tactical development in young rink hockey players (Juegos reducidos para el desarrollo técnico de jóvenes jugadores de hockey sobre patines) by Samuel Honório, Marco Batista, Jorge Santos, João Serrano, João Petrica, João Almeida, Miguel Camões

“… Rink hockey like any other team sport game is necessary to have a mastery of the game object "the ball" and for this it is necessary that athletes do not have a deficient training steps in that process, because it is during their development, that the athlete is in an optimal situation to improve on this aspect of the game. …”
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Understanding school frontline workers’ early implementation behavior: insights from the generation healthy kids study in Denmark by Jonas Vestergaard Nielsen, Sofie Koch, Tine Hyldahl Henriksen, Rikke Fredenslund Krølner, Line Lund, Louise Ayoe Sparvath Brautsch, Line Kattai Ulrikkeholm, Camilla Trab Damsgaard, Malte Nejst Larsen, Thomas Skovgaard

“…These findings highlight the need for adaptive, school-specific implementation strategies to sustain health-promoting interventions like GHK and suggest stakeholder engagement to further optimize implementation processes.…”
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Crosstalk Between the Oncoproteins of High‐Risk Human Papillomaviruses Types 16 and 18 in Colorectal Cancer Cell Models by Queenie Fernandes, Varghese Philipose Inchakalody, Sarra Mestiri, Takwa Bedhiafi, Shereena Hydrose, Sara S. Bashraheel, Maysaloun Merhi, Said Dermime, Ala‐Eddin Al Moustafa

“…We also report that HPV type 18 can induce a greater and more sustained oncogenic outcome as compared to HPV type 16. Conclusion Our data indicate that co‐expression of the E6/E7 oncoproteins of HPV types 16 and 18 can enhance oncogenic processes in CRC, especially TP53 mutant CRC.…”
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How health systems approached respiratory viral pandemics over time: a systematic review by Walter Ricciardi, Maria Luisa Di Pietro, Drieda Zaçe, Fidelia Cascini, Ilda Hoxhaj, Margherita Ferranti, Stefania Boccia

“…Double-blinded screening process was conducted by titles/abstracts and subsequently eligible full texts were read and pertinent data were extracted. …”
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Marked mucosal lipid shifts in treatment refractory inflammatory bowel disease: a lipidomic study by Øystein K. Moe, Qian Gao, Dawei Geng, Einar Jensen, Rasmus Goll, Oddmund Nestegard, Mona D. Gundersen, Jon R. Florholmen, T. Moritz

“…Statistical analyses of lipid levels were carried out using generalized least squares. Lipidomics data were log2-transformed and auto-scaled before analysis. …”
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