Adaptive optimization decision system for plate-fin heat Exchangers: An integrated approach to enhancing efficiency and performance by Na Sun, Shuai Zhang, Nan Li, Zijian Li, Meng He, Zhengchun Shen, Ke Wang, Xiaoyong Guo, Wen-Quan Tao

“…Cross-flow Plate-Fin Heat Exchangers (PFHEs) are crucial in industries like new energy vehicles and data centers. This study presents a self-adaptive optimization framework to improve PFHE performance, addressing energy challenges and aiding industry progress. …”
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Relevance of Cellular Homeostasis-Related Gene Expression Signatures in Distinct Molecular Subtypes of Breast Cancer by Sharda P. Singh, Chathurika S. Dhanasekara, Michael W. Melkus, Chhanda Bose, Sonia Y. Khan, Flavia Sardela de Miranda, Maria F. Mahecha, Prrishti J. Gukhool, Sahil S. Tonk, Se-Ran Jun, Sahra Uygun, Rakhshanda Layeequr Rahman

“…Pathway analysis highlighted the enrichment of processes related to autophagy, cellular stress response, apoptosis, glutathione metabolism, deacetylation, and oxidative stress in high-risk and basal-like tumors compared with Ultralow and Luminal A tumors, respectively. …”
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Investigation on Low Stress Scratching Abrasion Resistance Influencing Residual Stress in Nickel Chromium Alloyed Iron by Sandeep Mashetty A., Sampathkumaran P., Ranjitha P., Chithirai Pon Selvan, Shridhar Deshpande C., Avinash Lakshmikanthan, Manjunath Patel G.C.

“…Ni-hard irons, high chromium irons, and HCHC materials are commonly used in components like liners, bull rig segments, and orifices. These components are exposed to various types of failures, including abrasion, erosion, corrosion, and fatigue. …”
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Urban Expansion and Land Use Transformations in Midnapore City (2003–2024): Implications for Sustainable Development by Rakesh Ranjan Thakur, Debabrata Nandi, Anoop Kumar Shukla, Subhasmita Das, Sasmita Chand, Pankaj Singha, Roshan Beuria, Chetan Sharma

“…The study employs Landsat 5 and 8 imagery with 30 m spatial resolution which were processed through Maximum Likelihood Classifier (MLC) algorithms. …”
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Toward standardized methods in canine vaginal microbiome research: evaluation of storage, host DNA depletion, and database selection by Lotte Spanoghe, Guillaume Domain, Florin Posastiuc, Amanda Hettiarachchi, Adelaide Panattoni, Sebastiaan Theuns, Filip Van Immerseel, Geert Opsomer, Ann Van Soom, Penelope Banchi

“…ABSTRACT Standardized methods for investigating the canine vaginal microbiome are not available yet. Data using next-generation sequencing (NGS) are still limited, and methodologies lack consistency. …”
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Classification of and detection techniques for RNAi-induced effects in GM plants by Cecilia Diaz, Steve U. Ayobahan, Samson Simon, Luise Zühl, Andreas Schiermeyer, Elke Eilebrecht, Sebastian Eilebrecht

“…Detecting unintended effects is complex, often relying on bioinformatic tools and untargeted analyses like transcriptomics and metabolomics, though these methods require extensive genomic data. …”
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TAK-875 Mitigates β-Cell Lipotoxicity-Induced Metaflammation Damage through Inhibiting the TLR4-NF-κB Pathway by Xide Chen, Yuanli Yan, Zhiyan Weng, Chao Chen, Miaoru Lv, Qingwen Lin, Qiuxia Du, Ximei Shen, Liyong Yang

“…Metabolic inflammatory damage, characterized by Toll-like receptor 4 (TLR4) signaling activation, is a major mechanism underlying lipotoxicity-induced β-cell damage. …”
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A Possible Common Physics Picture Reflected by the Gamma-Ray Emission of the Galactic Center by Lin Nie, Yi-Qing Guo, Si-Ming Liu

“…In contrast, the bubble-like structure in the high-energy (TeV) spectrum is produced by protons accelerated during active phases of the Galactic center, through the same physical process. …”
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Exploration of machine learning approaches for automated crop disease detection by Annu Singla, Ashima Nehra, Kamaldeep Joshi, Ajit Kumar, Narendra Tuteja, Rajeev K. Varshney, Sarvajeet Singh Gill, Ritu Gill

“…Recent advancements in machine learning (ML) offer promising alternatives by automating the disease detection processes with high precision and efficiency. We comprehensively analyze various ML techniques, including Convolutional Neural Networks (CNNs), Recurrent Neural Networks (RNNs), Support Vector Machines (SVMs), Random Forest (RF), and Deep Learning Architectures like ResNet and Inception, among others, highlighting their methodologies, datasets, performance metrics, and real-world applications. …”
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Research discussion groups as a component of the development of practical skills of students in the field of training “Construction” by N. I. Taraseeva, O. V. Baulina, N. A. Dezhinova

“…The role of the head of the group is to arouse the interest of students to the proposed research topics, to teach them to use computer technology not only to search for data on new technical solutions, but also to exchange information between the participants of the educational process, i.e. search for like-minded people, including from other educational institutions in different regions.Work in research groups of technical creativity in many respects facilitates process of development of occupations and specialties, gives the chance to expand and deepen area of knowledge, allows students to direct process, and for teachers to transfer part of this experience to occupations in classes to large audience, to involve all wishing to new projects.This makes it possible to obtain better knowledge, increase the level of training and high learning outcomes of students and pupils, preparing them for admission to universities by increasing motivation through a variety offorms of technology, including e-learning, on-line training. …”
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Safety and efficacy of pharmacological approaches available for multisystem inflammatory syndrome in children (MIS-C): a systematic review by Yasothaa Velusamy, Govinathan Vivekanandan, Muhammad Hibatullah Romli, Aissvarya Shankar, Thilakavathy Karuppiah, Putri Yubbu

“…Data synthesis was conducted by extracting the information on drugs used, efficacy and side effects. …”
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Therapeutic potential of traditional Chinese medicine loaded nanocarriers in wound management: Current status and their future perspective by Jitendra Gupta, Devesh Kumar, Reena Gupta, Diksha Diwakar, Kumari Shanno, Arpan Kumar Tripathi, Akshay Kumar, Mohit Kumar

“…Introduction: Wound healing is the main physiological process that repairs tissue injury and maintains the body’s protective barrier. …”
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Role of the CaV1.2 distal carboxy terminus in the regulation of L-type current by Felipe Arancibia, Daniela De Giorgis, Franco Medina, Tamara Hermosilla, Felipe Simon, Diego Varela

“…In conclusion, our results suggest that the interaction between DCRD and PCRD is sufficient to bring about the current inhibition and alter the voltage-dependent inactivation, possibly in an allosteric manner. Additionally, our data suggest that the DCtermD competitively modifies the calcium-dependent mechanism. …”
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GradCAM-PestDetNet: A deep learning-based hybrid model with explainable AI for pest detection and classification by Ramitha Vimala, Saharsh Mehrotra, Satish Kumar, Pooja Kamat, Arunkumar Bongale, Ketan Kotecha

“…Additionally, Vision Transformers (ViT) and Swim Transformers were explored for their ability to process complex data patterns. To enhance model interpretability, GradCAM-PestDetNet integrates Gradient-weighted Class Activation Mapping (Grad-CAM), allowing better visualization of model predictions. • Uses YOLOv8 models (YOLOv8n for fastest inference at 1.86 ms/img) and transfer learning for pest detection ensuring that the system is viable for low-resource environments. • Employs an ensemble model (ResNet50, DenseNet, MobileNet) that achieved 67.07 % accuracy, 66.3 % F1-score and 68.1 % recall. …”
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A novel perspective on dissemination: somatic metastasis of germ cell tumors from the central nervous system by Shao-Pei Qi, Chuan Zhao, Jing-Jing Ge, Cheng Li, Feng-Jun Xue, Chi Zhao, Chen-Chen Kong, Hui-Jie Sun, Jing-Jing Zhang, Ya-Qi Zhang, Jun-Ping Zhang

“…Fisher’s exact test was used for categorical data analysis. The dissemination process was systematically analyzed. …”
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Evaluating impacts of the trichloroethylene metabolite S-(1,2-dichlorovyinyl)-L-cysteine on transcriptomic responses and cytokine release in a macrophage model: implications for pr... by Annella Benjamin, Erica Boldenow, Sammy Jaber, Kelly Bakulski, John Dou, Justin Colacino, Peter Mancuso, Sean Harris

“…Trichloroethylene (TCE) is a volatile synthetic chemical used in various industrial processes like metal degreasing. Large amounts of TCE have been released into the environment. …”
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Determining Factors for Supply Chain Services Provider Selection and Long-Term Relationship Maintenance: Evidence from Greece by Damianos P. Sakas, Nikolaos T. Giannakopoulos, Nikos Kanellos, Christos Christopoulos, Kanellos S. Toudas

“…<i>Methods:</i> The authors collected quantitative data from 81 firms that operate in various industrial sectors in Greece. …”
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RBM20 nucleotide sequence variant in a family with a dilated phenotype of left ventricular non-compaction by O. V. Kulikova, R. P. Myasnikov, A. N. Meshkov, E. A. Mershina, A. V. Kiseleva, E. A. Sotnikova, M. M. Kudryavtseva, M. S. Kharlap, M. G. Divashuk, A. A. Zharikova, R. K. Angarsky, S. N. Koretsky, D. А. Filatova, V. E. Sinitsyn, O. M. Drapkina

“…For clinical interpretation, nucleotide sequence variants in the genes associated with LVNC development were selected according to the available literature data, with frequencies &lt;0,5% in the gnomAD database. …”
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Role of cytokines in pathogenesis, diagnosis and efficiency evaluation of immunotherapy in various variants of sclerotic lichen in women by E. V. Kolesnikova, A. V. Zharov, G. A. Penzhoyan

“…Derinat was chosen due to the fact of being an agonist of Toll-like receptors, and a number of immunoregulatory effects, including the ability to modulate cytokine production and to exert a positive influence upon regeneration processes. …”
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Introduction to Volume 29, Issue 3 by Pau Pérez-Sales, Chris Dominey

“…We close Volume 29 with an issue of Torture Journal focused on measuring processes and results, a subject that has always been considered a priority for the sector. …”
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