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2961
Health implications of established and emerging stressors: design of the prospective New Jersey Population Health Cohort (NJHealth) Study
Published 2025-03-01“…Building on ecosocial, life course and stress process models, the NJHealth Study employs multimodal data collection to comprehensively measure stress-related factors at individual and societal levels. …”
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2962
Financing immunisation in Kenya: examining bottlenecks in health sector planning and budgeting at the decentralised level
Published 2024-10-01“…We applied an inductive thematic approach in analysing the qualitative data using NVIVO software. Findings The study found a lack of alignment between planning and budgeting processes, with planning being more inclusive compared to budgeting. …”
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2963
PENANAMAN NILAI-NILAI MORALITAS PADA ANAK DINI USIA (STUDI KASUS PADA SEBUAH LEMBAGA PENDIDIKAN TK DI SEMARANG)
Published 2012-01-01“…The data analyses in this study covered the domain, componential, taxonomy, andthematic analyses. …”
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2964
Mechanism of <italic>Hindu Datura</italic> in the Treatment of Rheumatoid Arthritis from the Perspective of Network Pharmacology
Published 2020-12-01“…Objective:To construct the active component target of <italic>Hindu datura</italic> and the disease target of rheumatoid arthritis by using network pharmacology, to predict the specific molecular signal and pathway of <italic>hindu datura</italic> in the treatment of rheumatoid arthritis, and to analyze its potential therapeutic target and molecular mechanism.Methods:All the chemical components of <italic>hindu datura</italic> were summarized and screened through Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP)database, retrieval was performed with the preset oral bioavailability(OB)≥30%and drug like(DL)≥0.18.Uniprot database was used to screen the entire correlation basis of the effective chemical compound.After screening the disease target with"rheumatoid arthritis"as the retrieval word using GeneCards and OMIM database, the superimposed target area between the drug target of <italic>hindu datura</italic> and the disease target of rheumatoid arthritis was summarized and analyzed, and it could be used as the prediction target gene of <italic>hindu datura</italic> for treating rheumatoid arthritis.Network targets were constructed and analyzed for the exported data based on Cytoscape 3.7.1 software and STRING 7.8 database.Finally, GO functional enrichment analysis and KEGG signal pathway analysis were performed to further screen the main targets and signal pathways.Results:①Through screening and analysis, 27 effective compounds, 318 corresponding target genes and 125 predicted target genes were obtained for the treatment of rheumatoid arthritis.②The core genes in PPI network mainly included JUN, AKT1, RELA, MAPK1, etc.③GO functional enrichment analysis showed that the biological process(BP)for the treatment of rheumatoid arthritis by <italic>hindu datura</italic> mainly involves response to lipopolysaccharide, response to lipopolysaccharide, response to molecule of bacterial origin, response to metalion, response to oxidative stress, response to steroid hormone, cellular response to oxidative stress, reactive oxygen species metabolic process, response to oxygen levels, etc..The cell component(CC)consisted of membrane raft, membrane region, plasma membrane raft and presynaptic membrane; molecular functions(MF)mainly involved the nuclear receptor activity, transcription factor activity(direct ligand regulated sequence-specific DNA binding), steroid hormone receptor activity, cytokine receptors, cytokine activity, DNA-binding transcription activator activity, RNA polymeraseⅡtranscription factor binding, kinase regulator activity, receptor ligand activity, etc.The analysis of KEGG signaling pathway showed that the obvious pathway of <italic>hindu datura</italic> in the treatment of rheumatoid arthritis may involve IL-17 signaling pathway, TNF signal pathway, HIF-1signalpathway, Toll-like receptor signal pathway, etc.Conclusion:The potential mechanism of <italic>hindu datura</italic> for the treatment of rheumatoid arthritis is to exert anti-inflammatory, analgesic and antioxidant effects, which involve a number of interactive signal pathways.…”
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2965
Structure of the Secretory Compartments in Goblet Cells in the Colon and Small Intestine
Published 2025-07-01“…This membrane is eliminated through the detachment of bubbles filled with another SG and surrounded with a double membrane or by collapse of the empty SG and transformation of the double membrane lacking a visible lumen into multilayered organelles, which move to the cell basis and are secreted into the intercellular space where the processes of dendritic cells are localized. These data are evaluated from the point of view of existing models of intracellular transport.…”
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2966
Understanding knowledge and media influence on people with hepatitis B in Senegal: a mixed-methods study
Published 2025-03-01“…Data on readers’ comments spaces were extracted using an inductive approach and were processed using thematic analyses. …”
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2967
Artificial intelligence (AI) in restorative dentistry: current trends and future prospects
Published 2025-04-01“…Key challenges include data privacy concerns, algorithmic bias, interpretability of AI decision-making processes, and the need for standardized AI training programs in dental education. …”
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2968
Economic and geographical disparities in global contribution to open access publishing in anaesthesiology: A bibliometric analysis
Published 2025-07-01“…Significant geographical and economic disparities exist in OA publication volume, likely due to limited investment and structural barriers in lower-income countries.…”
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2969
A deep dive into research trends in sports journalism
Published 2025-01-01“…The availability of sources and ways of processing news involving digital media have changed the landscape of sports journalism to become more complex. …”
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2970
Global Biomaterials Market: Potential Opportunities for Raw Materials of Animal Origin
Published 2021-06-01“…However, the Russian segment is likely to grow and expand its range of biomaterials. …”
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2971
Influence of EEG-based functional connectivity and inhibitory control on educational web search performance among adolescents
Published 2024-09-01“…Vergunov) was used to study inhibitory control. Statistical processing was performed using the Python programming language, and the data were analyzed using binary logistic regression and the non-parametric Mann-Whitney U test. …”
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2972
The Mediating Role of Customer Engagement on Brand Involvement and Emotional Brand Attachment
Published 2021-05-01“…This study is exploratory in nature, and is limited to a base of customers who are engaged with a brand, by simply liking it on Facebook. In this regard, a survey of 302 respondents provided data, by resorting to purposive sampling between the age groups of 18 – 55 years. …”
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2973
ANALYSIS OF POSSIBLE COMPLICATIONS AFTER CHEMICAL TEETH WHITENING
Published 2024-12-01“…The purpose of the study is to identify and analyze the likely complications that occur after the procedure of chemical teeth whitening. …”
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2974
Effectiveness of visual, auditory, and kinesthetic reading techniques on students’ reading comprehension: A sensory comparative study in the context of higher education
Published 2025-04-01“…Techniques involving kinesthetic activities—writing and typing—were more effective, likely due to deeper cognitive engagement from motor activity. …”
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2975
Determinants of Credit Access to Small Scale Enterprises: A Case Study of Centenary Bank Kabale Branch-Kabale District.
Published 2024“…Complex and lengthy lending processes were identified as major obstacles, with many SMEs noting that documentation requirements and processing delays discouraged them from applying for loans. …”
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2976
Renewable Energy Sources and the New Paradigm in Energy Engineering
Published 2019-12-01“…But, in a document of the European Commission [1] developed based on a comprehensive analysis of a large volume of scientific publications, it is mentioned that <em>“Mostly due to current methods of capture and data malpractice, approximately 50% of all research data and experiments is considered not reproducible, and the vast majority (likely over 80%) of data never makes it to a trusted and sustainable repository.”…”
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2977
Spatial patterning of chloroplasts and stomata in developing cacao leaves
Published 2025-04-01“…Abstract Leaf development and the coordinated formation of its key components is a fundamental process driving plant growth and adaptation. In tropical species like cacao, flush growth, a period of rapid leaf expansion, is particularly dependent on the optimized spatial patterns of chloroplasts and stomata. …”
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2978
Amphibalanus amphitrite begins exoskeleton mineralization within 48 hours of metamorphosis
Published 2020-09-01“…While extensive research has been conducted on the glue-like cement that barnacles use to adhere to surfaces, less is known about the barnacle exoskeleton, especially the process by which the barnacle exoskeleton is formed. …”
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2979
Geographic Named Entity Matching and Evaluation Recommendation Using Multi-Objective Tasks: A Study Integrating a Large Language Model (LLM) and Retrieval-Augmented Generation (RAG...
Published 2025-02-01“…By integrating newly added external address data with an advanced large language model (LLM) like GPT-4, it achieves precise address evaluation and recommendation. …”
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2980
Rainfall- Runoff Modelling using HEC-HMS and ANN for Shiavde, Upper Krishna Basin, India
Published 2024-04-01“…Total 17 years of daily rainfall and discharge data from 1999 to 2013 was considered for model development exercise. …”
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