Epigenetic mechanisms linking atherosclerosis to ischemic stroke: insights from DNA methylation and transcriptome integration by Binrong Ding, Yiqun Wang, Junfeng Li, Xuewei Zhang, Xuewei Zhang, Xuewei Zhang, Zhengqing Wan, Zhengqing Wan, Hao Wang

Get full text

A Longitudinal Study of the Bidirectional Temporal Dynamics Between Body Mass Index and Biological Aging by Peggy Ler, Jonathan K. L. Mak, Chandra A. Reynolds, Alexander Ploner, Nancy L. Pedersen, Juulia Jylhävä, Anna K. Dahl Aslan, Deborah Finkel, Ida K. Karlsson

“…ABSTRACT Background Obesity and aging share biological processes, but their relationship remains unclear, especially in late life. …”
Get full text

Guiding Principles for Transformation Towards Integrated Acute Care for Older Adults Close to Home: Lessons from Nine Dutch Regional Partnerships. A Realist Evaluation by Eline D. Kroeze, Gercora Hoitinga, Susanne M. Smorenburg, Janet L. MacNeil Vroomen, Anneke J. A. H. van Vught, Bianca M. Buurman

Get full text

Investigating Facilitators and Barriers in the Tendency of Older Adults to Third-Generation Universities by Sara Maghare Dehkordi, Samaneh Pourhadi, Masoud Lotfizadeh, Shima Sum

“…Results From all the interviews, 364 initial codes were drawn, and the codes obtained from data analysis were assigned to two themes, obstacles to the tendency of older adults to university, including 7 subthemes (changing the learning process with increasing age, distance, and transportation, lack of social trust, socio-economic problems, not having enough opportunities, the presence of disabilities in old age, concern for young people) and facilitating factors for the tendency of older adults to university, including 7 subthemes (existence of well-being and comfort in life, lack of responsibilities and costs, existence of support and special privileges, increasing the level of awareness and culture, localization University and programs, the participation of capable retirees in programs, the importance of different views or interests of people). …”
Get full text

Knowledge of nursing students on dysthanasia by Mariana Costa Matos, Darci de Oliveira Santa Rosa, Karla Ferraz dos Anjos

“…Those who defined the term described it as the excessive prolongation of life or death suffered from much pain, aggressive treatment that only prolongs the process of dying. …”
Get full text

Knowledge of nursing students on dysthanasia by Mariana Costa Matos, Darci de Oliveira Santa Rosa, Karla Ferraz dos Anjos

“…Those who defined the term described it as the excessive prolongation of life or death suffered from much pain, aggressive treatment that only prolongs the process of dying. …”
Get full text

EasyMetagenome: A user‐friendly and flexible pipeline for shotgun metagenomic analysis in microbiome research by Defeng Bai, Tong Chen, Jiani Xun, Chuang Ma, Hao Luo, Haifei Yang, Chen Cao, Xiaofeng Cao, Jianzhou Cui, Yuan‐Ping Deng, Zhaochao Deng, Wenxin Dong, Wenxue Dong, Juan Du, Qunkai Fang, Wei Fang, Yue Fang, Fangtian Fu, Min Fu, Yi‐Tian Fu, He Gao, Jingping Ge, Qinglong Gong, Lunda Gu, Peng Guo, Yuhao Guo, Tang Hai, Hao Liu, Jieqiang He, Zi‐Yang He, Huiyu Hou, Can Huang, Shuai Ji, ChangHai Jiang, Gui‐Lai Jiang, Lingjuan Jiang, Ling N. Jin, Yuhe Kan, Da Kang, Jin Kou, Ka‐Lung Lam, Changchao Li, Chong Li, Fuyi Li, Liwei Li, Miao Li, Xin Li, Ye Li, Zheng‐Tao Li, Jing Liang, Yongxin Lin, Changzhen Liu, Danni Liu, Fengqin Liu, Jia Liu, Tianrui Liu, Tingting Liu, Xinyuan Liu, Yaqun Liu, Bangyan Liu, Minghao Liu, Wenbo Lou, Yaning Luan, Yuanyuan Luo, Hujie Lv, Tengfei Ma, Zongjiong Mai, Jiayuan Mo, Dongze Niu, Zhuo Pan, Heyuan Qi, Zhanyao Shi, Chunjiao Song, Fuxiang Sun, Yan Sun, Sihui Tian, Xiulin Wan, Guoliang Wang, Hongyang Wang, Hongyu Wang, Huanhuan Wang, Jing Wang, Jun Wang, Kang Wang, Leli Wang, Shao‐kun Wang, Xinlong Wang, Yao Wang, Zufei Xiao, Huichun Xing, Yifan Xu, Shu‐yan Yan, Li Yang, Song Yang, Yuanming Yang, Xiaofang Yao, Salsabeel Yousuf, Hao Yu, Yu Lei, Zhengrong Yuan, Meiyin Zeng, Chunfang Zhang, Chunge Zhang, Huimin Zhang, Jing Zhang, Na Zhang, Tianyuan Zhang, Yi‐Bo Zhang, Yupeng Zhang, Zheng Zhang, Mingda Zhou, Yuanping Zhou, Chengshuai Zhu, Lin Zhu, Yue Zhu, Zhihao Zhu, Hongqin Zou, Anna Zuo, Wenxuan Dong, Tao Wen, Shifu Chen, Guoliang Li, Yunyun Gao, Yong‐Xin Liu

Get full text

Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast. by Melvin Bérard, Laura Merlini, Sophie G Martin

“…To understand the signaling changes in the proteome and phospho-proteome during sexual reproduction, we developed cell synchronization strategies and present (phospho-)proteomic data sets that dissect pheromone from starvation signals over the sexual differentiation and cell-cell fusion processes. …”
Get full text

The Prediction of the Compaction Curves and Energy of Bituminous Mixtures by Filippo Giammaria Praticò, Giusi Perri

“…However, characterising the compaction process during the design stage is challenging due to the unavailability of primary data, such as the compaction energy applied by the roller on-site. …”
Get full text

Developing English speaking skills: Getting used to speaking English in the family environment by Jingga Lydia Maharani, Sri Wahyuningsih

“…A qualitative method was used, with data collected through questionnaires distributed to five EFL university students. …”
Get full text

Design and Implementation of BIM-Based Construction Supervision Platform for Hydraulic Engineering by YANG Chuhua, RAO Fanwei, FU Zhihao, LIAO Xiangjun

“…With the continuous promotion of high-quality development of water conservancy in the new era,it has become an inevitable trend to make full use of information technologies such as BIM,digital twins,and simulations to integrate and innovate with the water conservancy industry.In hydraulic engineering,an intelligent management system focusing on “BIM+a whole life cycle” has been gradually formed.Centering on the construction stage of hydraulic engineering,this study uses the new generation of information technologies such as BIM,big data,3S,and three-dimensional (3D) visualization to build an advanced,practical,and safe construction supervision platform for hydraulic engineering that can integrate the basic and overall construction process information resources.It is expected that the platform can greatly reduce the risks and solve the problems such as insufficient cooperation among institutions,difficult information collection,poor data sharing and consistency,and low construction management efficiency. …”
Get full text

Lifelong education of persons with disabilities – obstacles, support, and recommendations for the improvement of university segment by Јana P. Mišović

“…Lifelong education of persons with disabilities can represent a strategy for improving their quality of life and social position as well as support to their autonomous living. …”
Get full text

A Study On Developing Fluency And Accuracy Skills In Teaching Turkish As A Second Language by Merve Ercan, Bilal Ferhat Karadağ

“…Semi-structured interview form was used in the data collection process. Interview data were analyzed with content analysis. …”
Get full text

Human microbiome-derived peptide affects the development of experimental autoimmune encephalomyelitis via molecular mimicryResearch in context by Xin Ma, Jian Zhang, Qianling Jiang, Yong-Xin Li, Guan Yang

Get full text

Obtaining multi-component chrome plated coatings for press tooling equipment by Borys Sereda, Andrii Udod

“… The purpose of our study is to obtain multicomponent chrome coatings alloyed with titanium and aluminum to strengthen the working surfaces of parts operated under aggressive conditions on equipment for vulcanizing products from new elastomeric materials using modern methods of surface hardening of materials, including the SHS technology, with the main goal of developing new approaches to improve the mechanical properties and extend the ser-vice life of materials. As part of this study, we plan to conduct a broad review of existing methods, thoroughly study the features of the SHS processes, conduct a series of experimental studies to determine the optimal process parameters, and analyze the data obtained to determine the effectiveness of the SHS method for improving the mechanical properties of materials and extending the service life of machine parts and equipment for vulcanizing products from new elastomeric materials. …”
Get full text

Unlocking sea turtle diving behaviour from low-temporal resolution time-depth recorders by Jessica Harvey-Carroll, Javier Menéndez-Blázquez, Jose Luis Crespo-Picazo, Ricardo Sagarminaga, David March

“…Here, we present a novel method to process low-resolution TDR data at 5-minute intervals and infer diving behaviour from loggerhead turtles (Caretta caretta) during their elusive pelagic life stage spanning extended periods (> 250 days). …”
Get full text

Anomaly Detection in Elderly Health Monitoring via IoT for Timely Interventions by Cosmina-Mihaela Rosca, Adrian Stancu

“…The collected data for average heart rate (AR), minimum (mR), maximum (MR), number of steps (S), deep sleep time (DST), and superficial sleep time (SST) is processed in real-time through a health anomaly detection algorithm (HADA), based on the dimensionality reduction method using PCA. …”
Get full text

CHANGES IN THE INCOMES AND EXPENDITURES OF HOUSEHOLDS IN POLAND AND THEIR REGIONAL RELATIONS by Beata Kasprzyk, Małgorzata Leszczyńska

Get full text

New perspectives on ethics and the laws of artificial intelligence by Eduardo Magrani

“…The continuous interaction between intelligent devices, sensors and people points to the increasing number of data being produced, stored and processed, changing, in various aspects and increasingly, our daily life. …”
Get full text

Motives and attitudes when choosing the medical profession among the first-course students at the Medical University – Sofia in the 2024/2025 academic year by Vidin Kirkov, Kremena Ivanova

“…The choice of a profession largely determines the life path of an individual, the development of his individual qualities and abilities, the development of his essential powers, and his realization as a labor and social being. …”
Get full text