Targeted lung cancer screening in the age of immunotherapies and targeted therapies – an economic evaluation for AustraliaResearch in context by Jacqueline Roseleur, Jonathan Karnon, Harry de Koning, Vivienne Milch, Katrina Anderson, Jacqui Real, Dorothy Keefe, Kevin ten Haaf

“…Interpretation: Targeted lung cancer screening is more cost-effective when costs and effects of novel therapies are applied, although impacts on cost-effectiveness are likely to be marginal. Funding: Cancer Australia.…”
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The relationship between food security, fruit and vegetable consumption, and health-related factors in the late COVID-19 pandemic in Czechia: a cross-sectional study by M. Ohno, J. Vávra, P. Jehlička

“…Individuals with BMI ≥ 25 kg/m2 had 30% higher odds of not having daily FV, with marginal significance (p = 0.05). Educational attainment, rather than income, was a key predictor of FV consumption. …”
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Parental Assessment of Postsurgical Pain in Infants at Home Using Artificial Intelligence–Enabled and Observer-Based Tools: Construct Validity and Clinical Utility Evaluation Study... by Fatos Sada, Paola Chivers, Sokol Cecelia, Sejdi Statovci, Kujtim Ukperaj, Jeffery Hughes, Kreshnik Hoti

“…Currently, there is a paucity of data on how parents identify and manage this pain at home using standardized pain assessment tools. …”
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Healthcare responding to violence and abuse in Brazil: a quasi-experimental difference-in-differences analysisResearch in context by Estela Capelas Barbosa, Stephanie Pereira, Loraine J. Bacchus, Manuela Colombini, Gene Feder, Lilia Blima Schraiber, Ana Flávia Pires Lucas d'Oliveira

“…Results are reported as marginal effects with 95% confidence intervals (CI). …”
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Engagement With Digital Health Technologies Among Older People Living in Socially Deprived Areas: Qualitative Study of Influencing Factors by Helen Chadwick, Louise Laverty, Robert Finnigan, Robert Elias, Ken Farrington, Fergus J Caskey, Sabine N van der Veer

“…However, despite often having the greatest health needs, people who are older or living in more socially deprived areas may be less likely to have access to these technologies and often lack the skills to use them. …”
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Multiple eco-regions contribute to the seasonal cycle of Antarctic aerosol size distributions by J. Brean, D. C. S. Beddows, E. Asmi, A. Virkkula, A. Virkkula, L. L. J. Quéléver, M. Sipilä, F. Van Den Heuvel, T. Lachlan-Cope, A. Jones, M. Frey, A. Lupi, J. Park, Y. J. Yoon, R. Weller, G. L. Marincovich, G. L. Marincovich, G. C. Mulena, G. C. Mulena, R. M. Harrison, R. M. Harrison, M. Dall'Osto

“…We utilise <span class="inline-formula"><i>k</i></span>-means cluster analysis to separate the PNSD data into six main categories. “Nucleation” and “bursting” PNSDs occur 28 %–48 % of the time between sites, most commonly at the coastal sites of Marambio and King Sejong where air masses mostly come from the west and travel over extensive regions of sea ice, marginal ice and open ocean and likely arise from new particle formation. …”
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Long-Term Outcomes Associated with Traumatic Brain Injury in Childhood and Adolescence: A Nationwide Swedish Cohort Study of a Wide Range of Medical and Social Outcomes. by Amir Sariaslan, David J Sharp, Brian M D'Onofrio, Henrik Larsson, Seena Fazel

“…On the population level, TBI explained between 2%-6% of the variance in the examined outcomes. Using hospital data underestimates milder forms of TBI, but such misclassification bias suggests that the reported estimates are likely conservative. …”
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Health‐Seeking Behavior of Patients With Dental Abscesses: A Cross‐Sectional Study by Kwame Adu Okyere Boadu, Richard Okyere Boadu, Abigail Achiaa Nyarko, Esther Priscilla Biamah Danquah, Victor Wireko Adu, Nana Atuahene Oti, John Billy Owusu Quarshie, Nana Bempong Owusu‐ Ankomah

“…Methods A cross‐sectional quantitative design was used to collect data from 100 participants through purposive sampling. …”
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Perspectives and experiences regarding pre-exposure prophylaxis (PrEP) in a community sample of Veterans with unhealthy alcohol use: overall and across sexual orientation and gende... by Olivia V. Fletcher, Kristine Beaver, Elizabeth J. Austin, Jenna van Draanen, E. Jennifer Edelman, Emily C. Williams

“…Groups that experience chronic stigma, discrimination, and/or other marginalization, such as sexual and gender minoritized groups, may have enhanced HIV risk related to unhealthy alcohol use. …”
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The effect of prone positioning on maternal haemodynamics and fetal wellbeing in the third trimester-A primary cohort study with a scoping review. by Laura Ormesher, Jessica Catchpole, Linda Peacock, Heather Pitt, Anastasia Fabian-Hunt, Dexter Hayes, Claudia Popp, Jason M Carson, Raoul van Loon, Lynne Warrander, Karli Büchling, Alexander E P Heazell

“…<h4>Introduction</h4>Supine sleep position is associated with stillbirth, likely secondary to inferior vena cava compression, and a reduction in cardiac output (CO) and uteroplacental perfusion. …”
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Reconstruction of the fast-ion deuterium distribution in a tritium-rich plasma in the JET DTE2 campaign by H. Järleblad, B.C.G. Reman, Y. Dong, M. Nocente, J. Eriksson, A. Valentini, M. Rud, A. Dal Molin, J. Garcia, Ye.O. Kazakov, D. Keeling, D. King, E.A. Lerche, R. Lorenzini, C. Maggi, M. Maslov, D. Moseev, D. Rigamonti, Bo S. Schmidt, Ž. Štancar, M. Tardocchi, M. Salewski, JET Contributors, the EUROfusion Tokamak Exploitation Team

“…The fast-ion deuterium distribution likely peaks in energy ( E ) at around $E\sim 60$ –70 keV and has a marginal high-energy tail ( $E\gtrsim 180$  keV). …”
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Sleep Health by Sexual Orientation among Women in the United States and Interrelations with Race/Ethnicity, Age, and Generational Cohort by Martinez-Miller EE, Gaston SA, Jackson II WB, Jackson CL

“…Non-heterosexual, compared to heterosexual women were more likely to use sleep masks. Among non-Hispanic Black women, non-heterosexual women were more likely to use sleep medications than heterosexual women. …”
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The effect of monopropylene glycol on milk production, uterine health, and reproductive performance in cows diagnosed with hyperketonemia on 3 pasture-based dairy farms by S.J. Hendriks, J.R. Roche, J.A.A. McArt, T.M. Grala, S-A. Turner, C.R. Burke, B. Kuhn-Sherlock, C.V.C. Phyn

“…The MPG-treated cows were 52% more likely (hazard ratio [HR] = 1.52, 95% CI: 1.30–1.76) to resolve HYK and 69% less likely (HR = 0.31, 95% CI: 0.17–0.58) to develop severe HYK compared with control cows. …”
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Effects of biochar, ligneous soil amendments, and a microbial stimulant on soil biological activity, and carbon content and stability after two-years of their application in a bore... by J. Heinonsalo, K. Peltokangas, P. Barré, F. Baudin, L. Cécillon, S. Kalu, S. Kanerva, K. Karhu, L. Kulmala, J. Liski, A.-R. Salonen, R. Shrestha, H. Soinne, E. Virtanen, K. Huusko, O.-M. Sietiö

“…Based on the extensive data we collected, mainly biochars increased soil organic carbon content enough to be detectable after two years. …”
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Modeling the distribution of the invasive snail Physella acuta in China: Implications for ecological and economic impact by Yingxuan Yin, Anyuan Xu, Xiaowen Pan, Qing He, Aoxun Wu, Linya Huang, Yinjuan Wu, Xuerong Li

“…As a result, the overall distribution center is likely to shift marginally northward. Conclusion: With the future climate change, the total suitable habitats of P. acuta in China showed a shrinking trend, and the shrinkage was more significant in the southern low-latitude suitable habitats. …”
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Clinicopathological Comparison Between <i>GREB1</i>- and <i>ESR1</i>-Rearranged Uterine Tumors Resembling Ovarian Sex Cord Tumors (UTROSCTs): A Systematic Review by Livia Maccio, Damiano Arciuolo, Angela Santoro, Antonio Raffone, Diego Raimondo, Susanna Ronchi, Nicoletta D’Alessandris, Giulia Scaglione, Michele Valente, Belen Padial Urtueta, Francesca Addante, Nadine Narducci, Emma Bragantini, Jvan Casarin, Giuseppe Angelico, Stefano La Rosa, Gian Franco Zannoni, Antonio Travaglino

“…No significant differences were detected with regard to margins, cytological atypia, necrosis, retiform pattern, and rhabdoid cells. …”
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Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study. by Vijay R Varma, Youjin Wang, Yang An, Sudhir Varma, Murat Bilgel, Jimit Doshi, Cristina Legido-Quigley, João C Delgado, Anup M Oommen, Jackson A Roberts, Dean F Wong, Christos Davatzikos, Susan M Resnick, Juan C Troncoso, Olga Pletnikova, Richard O'Brien, Eelko Hak, Brenda N Baak, Ruth Pfeiffer, Priyanka Baloni, Siamak Mohmoudiandehkordi, Kwangsik Nho, Rima Kaddurah-Daouk, David A Bennett, Shahinaz M Gadalla, Madhav Thambisetty

“…Study limitations include the small sample sizes in the BLSA cohort and likely inaccuracies in the clinical diagnosis of dementia subtypes in primary care settings.…”
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Clinical and cost-effectiveness of percutaneous nephrolithotomy, flexible ureterorenoscopy and extracorporeal shockwave lithotripsy for lower pole stones: the PUrE RCTs by Oliver Wiseman, Daron Smith, Kath Starr, Lorna Aucott, Rodolfo Hernández, Ruth Thomas, Steven MacLennan, Charles Terry Clark, Graeme MacLennan, Dawn McRae, Victoria Bell, Seonaidh Cotton, Zara Gall, Ben Turney, Samuel McClinton

“…The consistent drop in health status at week one in both trials, particularly for those in the FURS treatment arms has important implications for practice during consent to treatment. Based on this data it is important for clinicians to emphasise that patients are likely to feel worse before they feel better. …”
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Connectivity guided intermittent theta burst stimulation versus repetitive transcranial magnetic stimulation in moderately severe treatment resistant depression by Richard Morriss, Lucy Webster, Luke Ingram, Mohamed Abdelghani, Adriana Anton, Shaun Barber, Peter Bates, Paul Briley, Clement Boutry, Cassandra Brookes, Edward Cox, Beth Hall, Marilyn James, Matthew Keane, Micheal Kurkar, Sudheer Lankappa, Peter Liddle, Hamish McAllister-Williams, Hyerin Oh, Alexander O’Neill-Kerr, Jehill Parikh, Stefan Pszczolkowski, Ana Suazo Di Paola, Louise Thomson, Yvette Walters, Dorothee Auer

“…Sample size calculation A sample size of 266 participants provides 89.3% power to detect a mean difference of 3 points in the HDRS-17 over 26 weeks between the groups at a 5% two-sided significance level assuming a standard deviation (SD) of 8, with a correlation between follow-up measures of 0.7 and 20% data loss/drop-out. Statistical analysis Primary analysis of the primary outcome used the intention-to-treat (ITT) population with the multiple imputation technique being implemented to deal with missing data in instances where participants were missing any of the HDRS-17 scores. …”
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Evaluation of parenting interventions for those with additional health and social care needs during pregnancy: THRIVE a multi-arm RCT with embedded economic and process components by Marion Henderson, Anja Wittkowski, Katie Buston, Karen Crawford, Alice MacLachlan, Alex McConnachie, Emma McIntosh, Claudia-Martina Messow, Catherine Nixon, Rosaleen O’Brien, Shona Shinwell, Daniel Wight, Yiqiao Xin, Rachel Calam, Ruth Dundas, James Law, Helen Minnis, Lucy Thompson, Philip Wilson

“…Background Women who have additional social and care needs in pregnancy (e.g. social adversity, maternal depression and anxiety) are likely to produce high levels of stress hormones. …”
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