Integrating TNF-α with Established Tumor Markers to Enhance Prognostic Accuracy in Gastric Cancer: A Prospective Observational Study by Mihai Catalin Rosu, Cristi Tarta, Silviu Moldovan, Andreea-Adriana Neamtu, Andrei Ardelean, Marco Capitanio, Diana Herczeg, Ionut-Flaviu Faur, Renata Bende, Luminita Pilat, Virgiliu Mihai Prunoiu, Carmen Neamtu, Bogdan Dan Totolici

“…<b>Methods</b>: In this prospective observational study, we enrolled 80 gastric cancer patients and 20 non-neoplastic controls. Baseline clinical data, laboratory parameters, and tumor markers (CEA, CA19-9, CA72-4, AFP) were recorded. …”
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Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population by Zhanyi Yang, Jiaai Xu, Xiaoyu Yang, Pengcheng Yi, Jian Ruan, Yingying Wu, Yushan Li, Geng Tian, Fuyi Xu, Jia Mi, He Li, Chunhua Yang

“…This research aims to elucidate the function of MORC4 in hepatic lipid metabolism, thereby improving the understanding of the molecular mechanisms underlying lipid metabolism disorders.MethodsData regarding circulating lipid traits and hepatic Morc4 expression in BXD mice were obtained from GeneNetwork. …”
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CAP-m7G: A capsule network-based framework for specific RNA N7-methylguanosine site identification using image encoding and reconstruction layers by Peilin Xie, Jiahui Guan, Xuxin He, Zhihao Zhao, Yilin Guo, Zhenglong Sun, Lantian Yao, Tzong-Yi Lee, Ying-Chih Chiang

“…Dysregulation of m7G has been implicated in various diseases, including cancers and neurodegenerative disorders, where the loss of m7G can lead to genomic instability and uncontrolled cell proliferation. …”
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Apigenin inhibits NLRP3 inflammasome activation in monocytes and macrophages independently of CD38 by Knut Husø Lauritzen, Knut Husø Lauritzen, Kuan Yang, Michael Frisk, Mieke C. Louwe, Maria Belland Olsen, Maria Belland Olsen, Mathias Ziegler, William E. Louch, Bente Halvorsen, Bente Halvorsen, Pål Aukrust, Pål Aukrust, Arne Yndestad, Øystein Sandanger, Øystein Sandanger

“…Mice lacking CD38 are very susceptible to acute bacterial infections, implicating CD38 in innate immune responses. The effects of CD38 inhibition on NLRP3 inflammasome activation in human primary monocytes and monocyte-derived macrophages have not been investigated. …”
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Errors Associated With Medication Administration by a Nurse During Hospitalisation: A Prospective Observational Multicentric Study by Ondrej Tesar, Martin Dosedel, Ales Antonin Kubena, Katerina Mala‐Ladova, Radka Prokesova, Iva Brabcova, Hana Hajduchova, Martin Cerveny, Ivana Chloubova, Jiri Vlcek, Valerie Tothova, Josef Maly

“…Patient or Public Contribution Neither patients nor public was not involved in the design, data collection, or dissemination plans of this study. …”
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Fetal Akinesia/Hypokinesia and Arthrogryposis of Neuromuscular Origin: Etiologic Groups, Genetics, and Phenotypic Spectrum by Florencia Pérez‐Vidarte, Berta Estévez‐Arias, Leslie Matalonga, Delia Yubero, Anna Codina, Carlos Ortez, Julita Medina, Lidia DeSena DeCabo, Laura Carrera‐García, Jesica Expósito‐Escudero, Cristina Jou, Eduardo F. Tizzano, Andres Nascimento, Daniel Natera‐de Benito

“…The most frequently implicated genes were TTN (16%, 9/55), CHRNG (10.9%, 6/55), PIEZO2 (9.1%, 5/55), ZC4H2 (9.1%, 5/55), DYNC1H1 (7.2%, 4/55), MYH3 (5.4%, 3/55), and RYR1 (5.4%, 3/55). …”
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Diet Patterns Featuring Western-Style and Low-Preparation Foods Differentially Relate to Cognitive Function in Early Childhood From the STRONG Kids 2 Birth Cohort Study by Arden L McMath, Shelby A Keye, Jennifer M Barton, Corinne N Cannavale, Samantha J Iwinski, Kelly F Bost, Sharon M Donovan, Naiman A Khan

“…Background: Dietary intake in early life is implicated in cognitive development. Objectives: This study aimed to investigate how diet patterns derived at 2, 3 and 4 y old relate to executive functions and early cognitive and academic skills using data from the longitudinal STRONG Kids 2 cohort. …”
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Early rehabilitation challenges of surgical patients with COVID-19 infection - a single-arm study by Simić-Panić Dušica, Bošković Ksenija, Pantelinac Slobodan, Knežević Aleksandar, Jovićević Predrag, Kozios Apostolos, Janjić Nataša, Nikolić Nikola, Vojnović Larisa, Tomašević-Todorović Snežana

“…A very limited amount of data regarding the rehabilitation outcome of surgical patients with COVID-19 is available in the current literature. …”
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Exploring expressed concerns and uncanny feeling in patients with shortness of breath calling out-of-hours primary care by Michelle Spek, Dorien L. Zwart, Esther de Groot, Michelle R. Timmerman, Maarten van Smeden, Daphne C. A. Erkelens, Anna S. M. Dobbe, Mathé Delissen, Frans H. Rutten, Roderick P. Venekamp

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Orchestrated desaturation reprogramming from stearoyl‐CoA desaturase to fatty acid desaturase 2 in cancer epithelial‐mesenchymal transition and metastasis by Zhicong Chen, Yanqing Gong, Fukai Chen, Hyeon Jeong Lee, Jinqin Qian, Jing Zhao, Wenpeng Zhang, Yamin Li, Yihui Zhou, Qiaobing Xu, Yu Xia, Liqun Zhou, Ji‐Xin Cheng

“…Desaturases such as stearoyl‐CoA desaturase (SCD) and fatty acid desaturase 2 (FADS2) have been implicated in multiple cancers, and their dominant and compensatory effects have recently been highlighted. …”
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Exploring fecal microbiota signatures associated with immune response and antibiotic impact in NSCLC: insights from metagenomic and machine learning approaches by Wenjie Han, Wenjie Han, Yuhang Zhou, Yuhang Zhou, Yiwen Wang, Yiwen Wang, Xiaolin Liu, Tao Sun, Tao Sun, Junnan Xu, Junnan Xu, Junnan Xu

“…Additionally, CARD database annotation demonstrated that the majority of antibiotic resistance genes were associated with Bacteroidetes and Proteobacteria, implicating these taxa in shaping microbial-mediated therapeutic responses.ConclusionsThis study represents the first large-scale, cross-cohort integration of metagenomic data to identify reproducible GM signatures predictive of immune checkpoint inhibitor efficacy in LC. …”
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Correlated Resting-State Functional MRI Activity of Frontostriatal, Thalamic, Temporal, and Cerebellar Brain Regions Differentiates Stroke Survivors with High Compared to Low Depre... by Peter Goodin, Gemma Lamp, Rishma Vidyasagar, Alan Connelly, Stephen Rose, Bruce C. V. Campbell, Tamara Tse, Henry Ma, David Howells, Graeme J. Hankey, Stephen Davis, Geoffrey Donnan, Leeanne M. Carey

“…Fractional amplitude of frequency fluctuations (fALFF) data across three frequency bands (broadband, i.e., ~0.01–0.08; subbands, i.e., slow-5: ~0.01–0.027 Hz, slow-4: 0.027–0.07) was examined. …”
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Co-circulation and genetic characterization of genotype I and II feline bocavirus strains in domestic cats from Northern Vietnam by Hieu Van Dong, Giang Thi Huong Tran, Yen Hoang Thi Nguyen, Thiet Chi Ngo, Amonpun Rattanasrisomporn, Chaiwat Boonkaewwan, Dao Anh Tran Bui, Jatuporn Rattanasrisomporn

“…Background and Aim: Feline bocavirus (FBoV), a member of the Parvoviridae family, has been implicated in gastrointestinal and respiratory conditions in domestic cats. …”
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Dietary antioxidants and flavonoids are inversely associated with prostate cancer risk and mortality: evidence from NHANES and machine learning by Yanyang Jin, Dong-shan Lv, Li-po Zhou, Li Xiao, Guang-quan Tong, Abdallah Karim, Shuai Xue, Hongyang Tian, Cheng-cai Wang, Kun Feng, Ding-ming Song, You-liang Guan

“…BackgroundOxidative stress and dietary micronutrient imbalances have been implicated in prostate cancer (PCa) development and progression. …”
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Global research prospects and trends in TFH cells and tumors: a bibliometric analysis by Hao Lei, Jin Hu, Junpeng Zhu, Runze Li, Yu Zhao, Yaqi Zhao, Guisheng He, Tao Song, Chong Lu, Wuping Zheng, Lei Li, Chunping Liu, Hengyu Chen

“…TFH cells are also implicated in various conditions, including autoimmune diseases, cancer, infectious diseases, allergies, and vaccine reactions. …”
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A systematic review of the epidemiology and risk factors for severity and recurrence of hypertriglyceridemia-induced acute pancreatitis by Jiongdi Lu, Zhe Wang, Wentong Mei, Kaixin Peng, Liang Zhang, Gang Wang, Kedong Xu, Zheng Wang, Yunpeng Peng, Zipeng Lu, Xiaolei Shi, Guotao Lu, Li Wen, Feng Cao, Chinese Hypertriglyceridemia-Associated Pancreatitis Study Group (CHPSG)

“…A search of PubMed, Web of Science, and Cochrane databases was conducted to identify all relevant randomized controlled trials (RCTs), prospective, or retrospective cohort studies on HTG-AP. Data related to epidemiology and risk factors for severity and recurrence of HTG-AP were extracted and analyzed. …”
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Prenatal exposure to criteria air pollution and traffic-related air toxics and risk of autism spectrum disorder: A population-based cohort study of California births (1990–2018) by Karl O’Sharkey, Sanjali Mitra, Ting Chow, Seung-a Paik, Laura Thompson, Jason Su, Myles Cockburn, Beate Ritz

“…Background: Autism spectrum disorder (ASD) prevalence has risen steadily in California (CA) over several decades, with environmental factors like air pollution (AP) increasingly implicated. This study investigates associations between prenatal exposure to both criteria AP and traffic-related air toxics and ASD risk for 1990–2018 births. …”
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A resting-state fMRI cross-sectional study of cardiorespiratory fitness decline after stroke by Qingming Qu, Kexu Zhang, Hewei Wang, Hewei Wang, Jie Zhu, Jie Zhu, Yingnan Lin, Jie Jia, Jie Jia, Jie Jia

“…By employing resting-state functional magnetic resonance imaging (fMRI), we sought to identify specific brain areas that may be implicated in CRF decline among this patient population.MethodsA total of 22 patients with stroke and 15 healthy subjects matched for age, gender, and body mass index were recruited. …”
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The Resistin/TLR4/miR-155-5p axis: a novel signaling pathway in the onset of hypothalamic neuroinflammation by Marianne Prévost, Delphine Crépin, Sarah Al Rifai, Ghislaine Poizat, Mélanie Gonçalves, Femke van Barneveld, Rozhina Shadpay, Karim Taouis, Laure Riffault, Yacir Benomar, Mohammed Taouis

“…This approach revealed several common targets, including Quaking and Elmo1, genes implicated in microglial phagocytosis and engulfment. …”
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Wildlife hunting and the increased risk of leprosy transmission in the tropical Americas: a pathogeographical study by Alisa Aliaga-Samanez, Patricia D. Deps, Julia E. Fa, Raimundo Real, Jean-François Guégan, Marcela A. Oliveira, Aline Pessutti, Simon Knoop, Juliano A. Bogoni, Thais Q. Morcatty, Roberta Marques, Daniel Jiménez-García, Gabriel F. Massocato, Arnaud L. Desbiez, Danilo Kluyber, Hani R. El Bizri

“…In the tropical Americas, growing evidence implicates armadillos as important zoonotic reservoirs, particularly through direct contact during hunting and handling. …”
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