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15681
Functional Connectivity Alterations Associated with COVID-19-Related Sleep Problems: A Longitudinal Resting-State fMRI Study
Published 2025-01-01“…Correlations between FC and clinical data were analyzed by Pearson correlation analysis with Gaussian random field (GRF) correction. …”
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15682
Interfered long non-coding RNA HELLPAR or up-regulated microRNA-448 inhibits nasopharyngeal carcinoma progression via suppression of ADAM10
Published 2025-05-01“…While HELLP-associated long non-coding RNA (HELLPAR), microRNA-448 (miR-448), and a disintegrin and metalloprotease 10 (ADAM10) have been implicated in other malignancies, their regulatory interplay and functional roles in NPC remain unclear. …”
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15683
The role of JPT1 in hepatocellular carcinoma: tumor progression, microtubule dynamics regulation, and potential mechanisms within the immune microenvironment
Published 2025-07-01“…Methods This study integrated data from TCGA-LIHC and GEO (GSE14520) databases to systematically investigate the expression profile of JPT1 and its association with clinicopathological features and prognosis in HCC patients. …”
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15684
Mitochondria-associated programmed cell death: elucidating prognostic biomarkers, immune checkpoints, and therapeutic avenues in multiple myeloma
Published 2024-12-01“…Mitochondrial dysfunction and dysregulated programmed cell death (PCD) pathways have been implicated in MM pathogenesis. However, the precise roles of mitochondria-related genes (MRGs) and PCD-related genes (PCDRGs) in MM prognosis remain unclear.MethodsTranscriptomic data from MM patients and healthy controls were analyzed to identify differentially expressed genes (DEGs). …”
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15685
Lipopolysaccharide-binding protein (LBP): a prognostic biomarker for gastric cancer linked to immune infiltration
Published 2025-03-01“…Lipopolysaccharide-binding protein (LBP), implicated in cancers such as lung, colon, and cervical cancer, has emerged as a promising candidate. …”
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15686
The role of the MicroBiome in PANCreatic cancer and its precursors— the study protocol of the MiBiPanc systematic review and meta-analysis
Published 2025-07-01“…Although the human microbiota contributes to health by supporting nutritional and hormonal homeostasis, modulating inflammation, detoxifying harmful compounds, and producing beneficial metabolites, several studies have implicated its crucial modulatory role in numerous diseases, including cancer. …”
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15687
The vitamin D receptor is essential for the replication of pseudorabies virus
Published 2024-12-01“…Moreover, the PI3K/AKT/mTORC1 and AMPK/mTORC1 pathways were also enriched in our RNA-seq data. Interfering with VDR expression, or chelating Ca2+ using BAPTA-AM, markedly impacted the activation of PI3K/AKT/mTORC1 and AMPK/mTORC1 pathways, lipid synthesis, and PRV proliferation. …”
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15688
HORMONE IMBALANCE AS A MANIFESTATION OF STRESS IN THE FORMATION OF OLIGOMENORRHEA IN TEENAGE GIRLS
Published 2025-07-01“…Differences were considered significant at ρ < 0.05. Data are presented as mean ± standard deviation (SD) and frequency counts. …”
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15689
Impact of Surgeon Specialty on Ankle Arthrodesis Readmission, Complication, and Infection Rates: A Medicare Analysis
Published 2024-12-01“…To help mitigate bias, we also performed a propensity matched model with the same variables. Data were reported as percentage point (PPT) differences (95% CI) between groups, with a positive number indicating higher rate of complications among patients treated by non-orthopedic surgeons. …”
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15690
NPR is an independent risk factor for predicting all-cause mortality in patients with metabolic dysfunction-associated steatotic liver disease: evidence from NHANES 2007–2020
Published 2025-04-01“…Methods In this historical cohort study, data from 8051 adults aged 20 years and older were analysed. …”
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15691
Investigating the synergistic effects of gamma-glutamyl transferase with homocysteine, ferritin, and uric acid in patients with type II diabetes mellitus
Published 2025-03-01“…Serum glucose and ferritin levels were measured using the Cobas E411 autoanalyzer (ECL method), and γ-GT, Hcy, and UA levels were measured using the Pentra C400 analyzer (photometric method). Data were analyzed using XLSTAT and SPSS software. …”
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15692
Lymph Node Exosomes Delivery Attenuates Myocardial Ischemia-Reperfusion Injury via Regulating PTEN-PI3K/Akt Pathway Mediated Myocardiocyte Apoptosis
Published 2025-04-01“…MiRNA-sequencing of KLF2-EXO implicated that miRNA-486-5p (miR-486-5p) was a potent candidate mediator that inhibited myocardiocyte apoptosis, and the miR-486-5p antagomir reversed the effect. …”
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15693
Transcriptional Sequencing and Gene Expression Analysis of Various Genes in Fruit Development of Three Different Black Pepper (Piper nigrum L.) Varieties
Published 2020-01-01“…Comparison of flower and fruit transcriptome data from the three different black pepper varieties revealed a large number of DEGs between flower and fruit of the SA variety. …”
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15694
Apolipoprotein E-ε4 allele is associated with perihematomal brain edema and poor outcomes in patients with intracerebral hemorrhage
Published 2025-02-01“…We enrolled patients with supratentorial ICH patients and analyzed ApoE gene alleles, clinical baseline data, blood biochemical indices, and imaging findings. …”
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15695
Association between periodontitis and blood lipid levels: a cross-sectional study
Published 2025-07-01“…Abstract Background Dyslipidemia has been implicated as a risk factor for periodontitis; however, the underlying mechanisms remain poorly understood. …”
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15696
Carbapenem-resistance in Acinetobacter baumannii: prevalence, antibiotic resistance profile and carbapenemase genes in clinical and hospital environmental strains
Published 2025-06-01“…Abstract Background Acinetobacter baumannii, a Gram-negative member of the ESKAPE pathogen group, is known to develop resistance to several antibiotics rapidly, and carbapenem-resistant A. baumannii (CRAB) is highly implicated in life-threatening infections, especially within hospital settings. …”
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15697
Selenium supplementation and insulin resistance in a randomized, clinical trial
Published 2019-05-01“…Objective While controversial, observational and randomized clinical trial data implicate the micronutrient selenium (Se) in the development of type 2 diabetes (T2D). …”
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15698
A pan-cancer analysis of the oncogenic function of HMGB1 in human tumors
Published 2024-12-01“…Additionally, we discovered that the frequency of HMGB1 mutations ranked among the top 20 mutated genes in the 95 patients’ data, indicating that HMGB1 plays an important role in the development and prognosis of various solid tumors. …”
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15699
A Study of the Relationship Among Radon, Thoron and Radioactive Aerosol Particle Distribution in PM<sub>2.5</sub> Risk Areas in Kanchanaburi Province, Thailand
Published 2024-11-01“…Nevertheless, as this study was conducted during the non-burning period, future research must be conducted during the burning season, using supplementary factors to acquire more thorough data.…”
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15700
Unraveling the genetic blueprint of doxorubicin-induced cardiotoxicity through systems genetics approaches
Published 2025-06-01“…Most of the top candidates showed cardiomyocyte specific expression based on scRNA-seq data. Conclusions Survival, BW loss, and echocardiography parameters considerably varied among DOX-treated BXDs, suggesting significant influence of genetic background on expression of those traits. …”
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