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15621
Barriers and enablers of early health-seeking behaviour among women with preeclampsia and eclampsia: a qualitative study at a National referral hospital in Uganda
Published 2025-08-01“…This involved searching for a variation in the special aspects of the study population, including age, condition/diagnosis of either preeclampsia or eclampsia and the timing of diagnosis. Data were collected using a semi-structured interview guide from July to August 2023 and analysed manually through inductive content analysis. …”
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15622
Pathogenicity and virulence of Aeromonas schubertii in farmed Asian seabass (Lates calcarifer) in Thailand
Published 2025-07-01“…Abstract Background Aeromonas schubertii, an emerging pathogen primarily recognized in humans, shrimps, and other mammals, is increasingly implicated in aquatic animal diseases. Despite its growing prevalence, reports of its involvement in fish diseases are limited. …”
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15623
The impact of practical aspects of communication and thinking skills formation on improving self-management skills in university students
Published 2020-10-01“…The research hypotheses were validated, and the obtained data were statistically processed.Results. The survey results indicate that there is a substantial difference in male and female student perspectives regarding the impact of communication and thinking skills. …”
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15624
The polarity protein Par3 enhances renal cell carcinoma metastasis via YAP/TAZ activation
Published 2025-07-01“…Interestingly, Par3’s functions vary among cancers: both Par3 elevation (in the prostate or liver) and loss (in the breast or lung) have been implicated in cancer metastasis. Although Par3 overexpression has been correlated with diminished survival in renal cell carcinoma (RCC), data indicating the role of Par3 in RCC metastasis are lacking. …”
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15625
Integrative Machine Learning Approach to Explore Glycosylation Signatures and Immune Landscape in Moyamoya Disease
Published 2025-05-01“…Although abnormal glucose metabolism has been implicated, the contribution of glycosylation-related genes in MMD remains elusive. …”
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15626
Immunological profiling in type 2 diabetes mellitus and type 2 diabetic kidney disease: insights from single-cell LacNAc sequencing
Published 2025-08-01“…Correlative data suggest that targeting ROS and the CXCL8/CXCR2 pathway may represent potential therapeutic directions, though preclinical validation is warranted.…”
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15627
Identification of ZNF652 as a Diagnostic and Therapeutic Target in Osteoarthritis Using Machine Learning
Published 2024-12-01“…Zinc Finger Protein 652 (ZNF652) is a transcription factor implicated in various biological processes. Nevertheless, its role in OA has not been elucidated.Methods: The search term “osteoarthritis” was utilized to procure transcriptome data relating to OA patients and healthy people from the Gene Expression Omnibus (GEO) database. …”
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15628
Association of serum 25-hydroxyvitamin D levels with age-related macular degeneration and its clinical correlates: a cross-sectional study
Published 2025-08-01“…Comprehensive ophthalmic assessments and laboratory tests were performed. Data were analyzed using R software, employing Student’s t-tests, ANONA, chi-squared tests, Pearson correlation and linear regression models.ResultsAMD patients exhibited significantly lower serum 25(OH)D levels than controls (22.98 ± 7.30 ng/mL vs. 26.12 ± 9.81 ng/mL, p=0.013). …”
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15629
Association between dietary vitamin intake and all-cause mortality in ovarian cancer patients: a prospective cohort study
Published 2025-05-01“…BackgroundWhile various lifestyle factors have been implicated in cancer prognosis, the role of dietary vitamins in ovarian cancer survival is not well understood. …”
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15630
Assessing correlation between different temporary restorative materials for microleakage following endodontic treatment: an in-vitro study
Published 2024-12-01“…Depth of dye penetration was measured. The collected data were statistically analyzed (α = 0.05). Results Gp 7: Teflon + Systemp. inlay obtained the lowest infiltration values with no significant difference than (Gp 4: Systemp.inlay) and (Gp 8: Teflon + Cavit-W). …”
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15631
Fibroblast activation protein-α is a potential prognostic biomarker related to ferroptosis in head and neck squamous cell carcinoma
Published 2025-06-01“…Fibroblast activation protein (FAP) has been implicated in HNSC progression, but its specific involvement in ferroptosis and the ceRNA network is still not well understood.In this study, data from The Cancer Genome Atlas (TCGA) HNSC dataset were analyzed to examine the relationship between FAP expression and drug sensitivity, clinical features, methylation status, ferroptosis, immune infiltration, prognosis, and ceRNA networks. …”
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15632
Low Baseline Interleukin-17A Levels Are Associated with Better Treatment Response at 12 Weeks to Tocilizumab Therapy in Rheumatoid Arthritis Patients
Published 2015-01-01“…T helper 17-related cytokines have been implicated in rheumatoid arthritis (RA) pathogenesis. …”
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15633
Cytological Characterization of <i>vrnp 1</i>, a Pollen-Free Male Sterile Mutant in Mung Bean (<i>Vigna radiata</i>)
Published 2025-01-01“…Our research may elucidate how the delayed initiation of programmed cell death in tapetal cells contributes to a factor implicated in mung bean male sterility. Furthermore, the phenotypic data collected during pivotal developmental phases may have contributed to a better grasp of mung bean microspores and anther development.…”
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15634
Benchmarking AlphaMissense pathogenicity predictions against APP, PSEN1, and PSEN2 variants of unknown significance
Published 2025-06-01“…AlphaMissense (AM) is a novel technology that uses population frequency data along with structural and sequential contexts from AlphaFold to predict the pathogenicity of missense mutations. …”
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15635
Lysine-specific demethylase 1 regulates hematopoietic stem cell expansion and myeloid cell differentiation
Published 2025-08-01“…We provide functional data implicating Prtn3 as an effector of the stem cell expansion and myeloid maturation block caused by the loss of LSD1.…”
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15636
Which Classes of Antibiotics Are Associated with the Acquisition of Carbapenemase-Producing Enterobacterales?
Published 2025-07-01“…While animal studies have suggested that certain antibiotic classes may increase the risk of CPE acquisition, clinical data identifying which classes are most implicated remain limited. …”
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15637
Deciphering mitochondrial dysfunction in keratoconus: Insights into ACSL4 from machine learning-based bulk and single-cell transcriptome analyses and experimental validation
Published 2025-01-01“…Single cell sequencing data highlighted ACSL4 as the most promising biomarker, primarily expressed in corneal stromal cells (CSCs). …”
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15638
Immunization with Complete Freund’s Adjuvant Reveals Trained Immunity-like Features in A/J Mice
Published 2025-07-01“…Specifically, we observed an increased level of lactate, indicative of aerobic glycolysis, which is implicated in TI, and this was also detected in the IFA group. …”
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15639
RETRACTED ARTICLE: Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies
Published 2022-01-01“…Based on these preclinical data, we selected the PV-1950D vaccine for future IND enabling preclinical studies and clinical development.…”
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15640
Expression of Periostin Alternative Splicing Variants in Normal Tissue and Breast Cancer
Published 2024-08-01“…However, it has been implicated in the pathogenesis of various malignant tumors and chronic inflammatory diseases. …”
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