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15561
Ambient Air Pollution Exposure and Adverse Outcomes Among Medicare Beneficiaries With Heart Failure
Published 2024-08-01“…Background Exposure to fine particulate matter (<2.5 um, particulate matter with an aerodynamic diameter <2.5 microns [PM2.5]) has been implicated in atherogenesis. Limited data in animal studies suggest that PM2.5 exposure leads to myocardial fibrosis and increased incidence of heart failure (HF). …”
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15562
Association between the difference in estimated GFR based on cystatin C versus creatinine in coronary artery diseases
Published 2025-12-01“…However, primary prevention of the risk of coronary artery disease (CAD) is equally important but there is a lack of studies specifically investigating this implication.Methods This prospective cohort study utilized data from the UK Biobank, including 437,536 participants without CAD at baseline. …”
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15563
Diverse regulated cell death patterns and immune traits in kidney allograft with fibrosis: a prediction of renal allograft failure based on machine learning, single-nucleus RNA seq...
Published 2024-12-01“…Regulated cell death has been widely implicated in various kidney diseases, including renal fibrosis. …”
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15564
Metabolomics insights into the protective molecular mechanism of Vaccinium myrtillus against oxidative stress in intestinal cells
Published 2025-03-01“…Chemometric approaches were applied to preprocess the data, explore variability, and identify systematic biases, ensuring the removal of batch effects and other experimental artifacts. …”
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15565
Association between advanced glycation end products and estimated glomerular filtration rate: a cross-sectional analysis
Published 2025-05-01“…Methods We conducted a cross-sectional analysis of baseline data from the Health Workers Cohort Study (2004–2006), which included 1,621 adults. …”
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15566
A20 as a Potential Therapeutic Target for COVID‐19
Published 2025-01-01“…A20, which is widely accepted as a pivotal regulator of inflammation, has been shown to be implicated in the processes of antiviral responses and immunosuppression. …”
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15567
Rare variant associations with birth weight identify genes involved in adipose tissue regulation, placental function and insulin-like growth factor signalling
Published 2025-01-01“…We report analyses of rare variants that impact birth weight when carried by either fetus or mother, using whole exome sequencing data in up to 234,675 participants. Rare protein-truncating and deleterious missense variants are collapsed to perform gene burden tests. …”
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15568
Acceptance‐Hesitancy of COVID‐19 Vaccination and Factors Affecting It in Adults: Systematic Review Study
Published 2024-11-01“…The most frequently employed method of data collection was the online survey. The study sample comprised 59.12% women and 40.88% men, with ages ranging from 16 to 78 years. …”
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15569
Surfactant-derived protein type B: a new biomarker linked to respiratory failure and lung damage in mild to moderate SARS-CoV-2 pneumonia
Published 2024-11-01“…Surfactant proteins A and D (SP-A and SP-D) are implicated in COVID-19 lung damage, but the role of surfactant protein B (SP-B) remains unclear. …”
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15570
Nanosecond laser induces proliferation and improved cellular health within the retinal pigment epithelium
Published 2025-03-01“…Furthermore, melanin and lipofuscin content were restored to wildtype levels in laser-treated ApoEnull RPE, while melanolipofuscin granules were reduced within treated regions of human RPE.ConclusionThis work shows nanosecond laser stimulates RPE proliferation and results in an improved cellular phenotype. These data provide a biological basis for the prophylactic use of nanosecond lasers in AMD.…”
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15571
Neuromuscular transmission deficits in patients with CMT and ClC‐1 inhibition in CMT animal models
Published 2025-02-01“…Preclinical studies implicate neuromuscular junction (NMJ) transmission deficits in muscle dysfunction in CMT. …”
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15572
Protein expression profiling identifies a prognostic model for ovarian cancer
Published 2022-07-01“…Development of reliable models can facilitate prognosis monitoring and help relieve the distress. Methods Using the data archived in the TCPA and TCGA databases, proteins having significant survival effects on ovarian cancer patients were screened by univariate Cox regression analysis. …”
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15573
Genome-Wide Dissection of Novel QTLs and Genes Associated with Weed Competitiveness in Early-Backcross Selective Introgression-Breeding Populations of Rice (<i>Oryza sativa</i> L.)
Published 2025-04-01“…Candidate genes identified within these QTLs are implicated in the plant’s response to various abiotic and biotic stresses. …”
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15574
Changing patterns of Oral & Maxillofacial injuries before and during COVID-19 pandemic: A retrospective study
Published 2022-09-01“…We need more coordinated strategies of action to minimize maxillofacial injuries and its implication on physical and psychological wellbeing of patients.…”
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15575
Gut microbiota and derived metabolites mediate obstructive sleep apnea induced atherosclerosis
Published 2025-12-01“…Since we and others have implicated gut microbiota and metabolites in atherogenesis, we dissected their contributions to OSA-induced atherosclerosis. …”
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15576
Boundary spanning increases knowledge and action on invasive species in a changing climate
Published 2024-10-01“…By synthesizing and translating research and practitioner knowledge, boundary‐spanning activities could support proactive, research‐informed conservation practice, but the success of these efforts is rarely evaluated. Using repeat survey data from the Northeast Regional Invasive Species and Climate Change (NE RISCC) Management Network, a boundary‐spanning organization, we evaluate whether participating in NE RISCC affected practitioners' knowledge, actions and priorities related to invasive species management under a changing climate. …”
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15577
Detecting the contribution of V5/MT in reading, reading-related tasks, eye-movements and EEG-oscillations in children and adolescents with developmental dyslexia via high-definitio...
Published 2025-07-01“…Participants will read a text during each hd-tDCS condition. We will collect data on reading (text, lists of words and nonwords), reading-related processes (visual motion perception, rapid automatized naming of letters and numbers, phoneme blending), and physiological measures (eye movements, EEG-oscillations). …”
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15578
The metastatic role of the CXCL10-CXCR3 axis and its therapeutic potential in osteosarcoma
Published 2025-06-01“…Collectively, our data indicate the CXCL10-CXCR3 axis as a key metastatic driver in OS, suggesting CXCR3 as a viable therapeutic target for treating OS metastasis.…”
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15579
Penfluridol suppresses MYC-driven ANLN expression and liver cancer progression by disrupting the KEAP1–NRF2 interaction
Published 2024-12-01“…Analysis of The Cancer Genome Atlas data showed that high ANLN expression is associated with poor prognosis and survival in HCC patients. …”
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15580
The characterization of serum proteomics and metabolomics across the cancer trajectory in chronic hepatitis B‐related liver diseases
Published 2024-12-01“…Our extensive analysis provides valuable proteomic and metabolomic data resources that will contribute to a deeper understanding of liver disease progression and enhance the identification of potential therapeutic targets.…”
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