Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. by Clint L Miller, Ulrike Haas, Roxanne Diaz, Nicholas J Leeper, Ramendra K Kundu, Bhagat Patlolla, Themistocles L Assimes, Frank J Kaiser, Ljubica Perisic, Ulf Hedin, Lars Maegdefessel, Heribert Schunkert, Jeanette Erdmann, Thomas Quertermous, Georg Sczakiel

“…Lastly, miR-224 and TCF21 were localized in human coronary artery lesions and anti-correlated during atherosclerosis. Together, these data suggest that miR-224 interaction with the TCF21 transcript contributes to allelic imbalance of this gene, thus partly explaining the genetic risk for coronary heart disease associated at 6q23.2. …”
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BAIAP2 as a driver of tumor progression in urothelial bladder cancer by Long Huang, Dong Yan, Honglian Ruan, Qiongqiong Lin, Haide Qin

“…Methods This study investigated the role of BAIAP2 in UBC using single-cell data analysis, bioinformatics, and functional assays. …”
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La práctica de la atención plena en estudiantes universitarios. Dificultades y facilidades percibidas Mindfulness Practices in University Students.Positive and NegativeAspectsPerce... by Inmaculada Canales-Lacruz, Glòria Rovira

“…NUDIST 6 software was used for data analysis. Results show that PMI improve students’ welfare through stress relief, introspection (maximum self-implication in the present moment) and self-realization (an increase in sensory awareness and self-regulation). …”
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Strong association between hypocalcemia and preeclampsia-eclampsia among pregnant women attending at a tertiary referral hospital in Northwestern Tanzania by Godluck H. Mlay, Prosper A. Shayo, Richard F. Kiritta, Dismas K. Matovelo, Benson R. Kidenya

“…The status of maternal hypocalcemia has been implicated in the pathogenesis of PE-E. However, there are controversial findings from previous studies done to assess the association between maternal hypocalcemia with PE-E. …”
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The independent and interactive effects of heavy metal pollution and vitamin D deficiency on early kidney injury indicators: analysis of the National Health and Nutrition Examinati... by Shuhui Jing, Yuan Ge, Juan Pan, Pei Chang, Xi Qiao

“…Vitamin D has been implicated in mitigating the oxidative stress and inflammatory reactions triggered by heavy metal exposure. …”
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Community effectiveness of pyriproxyfen as a dengue vector control method: A systematic review. by Dorit Maoz, Tara Ward, Moody Samuel, Pie Müller, Silvia Runge-Ranzinger, Joao Toledo, Ross Boyce, Raman Velayudhan, Olaf Horstick

“…Removal of duplicates, screening of abstracts and assessment for eligibility of the remaining studies followed. Relevant data were extracted, and a quality assessment conducted. …”
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Elevated POSTN expression predicts poor prognosis and is associated with radioresistance in cervical cancer patients treated with radical radiotherapy by Cui-qin Huang, Wen-tao Xiao, Xiang-rong Yao, Zhi-min Li, Jun-yan He

“…Periostin (POSTN), a matricellular protein within the tumor microenvironment, has been implicated in the promotion of tumor progression and treatment resistance, particularly through mechanisms such as epithelial-mesenchymal transition (EMT). …”
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The Phosphatase PHLPP2 Plays a Key Role in the Regulation of Pancreatic Beta-Cell Survival by Marta Letizia Hribal, Elettra Mancuso, Gaetano Paride Arcidiacono, Annalisa Greco, Donatella Musca, Teresa Procopio, Mariafrancesca Ruffo, Giorgio Sesti

“…Here, taking advantage of an in vitro model of chronic exposure to high glucose, we demonstrated that PHLPPs, particularly the second family member called PHLPP2, are implicated in the ability of pancreatic β cells to deal with glucose toxicity. …”
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Immunological characteristics in elderly COVID-19 patients: a post-COVID era analysis by Yunhui Li, Yuan Chen, Jing Liang, Yajie Wang

“…Furthermore, the transcriptomic data of CD4+ T cells were extracted from Gene Expression Omnibus (GEO) database. …”
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Whole Exome Sequencing in Atrial Fibrillation. by Steven A Lubitz, Jennifer A Brody, Nathan A Bihlmeyer, Carolina Roselli, Lu-Chen Weng, Ingrid E Christophersen, Alvaro Alonso, Eric Boerwinkle, Richard A Gibbs, Joshua C Bis, NHLBI GO Exome Sequencing Project, L Adrienne Cupples, Peter J Mohler, Deborah A Nickerson, Donna Muzny, Marco V Perez, Bruce M Psaty, Elsayed Z Soliman, Nona Sotoodehnia, Kathryn L Lunetta, Emelia J Benjamin, Susan R Heckbert, Dan E Arking, Patrick T Ellinor, Honghuang Lin

“…We examined whole exome sequencing data in a large community-based sample of 1,734 individuals with and 9,423 without AF from the Framingham Heart Study, Cardiovascular Health Study, Atherosclerosis Risk in Communities Study, and NHLBI-GO Exome Sequencing Project and meta-analyzed the results. …”
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Linkage study of voltage-gated potassium channels in familial mesial temporal lobe epilepsy Análise de ligação dos canais de potássio voltagem-dependente na epilepsia de lobo tempo... by Cláudia Vianna Maurer-Morelli, Rafael Breglio Marchesini, Rodrigo Secolin, Neide Ferreira Santos, Eliane Kobayashi, Fernando Cendes, Iscia Lopes-Cendes

“…In the present study, linkage data showed no evidence that VGKC are involved in the determination of HA in FMTLE.…”
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Insulin-Like Growth Factor 1 (IGF- 1) Levels And Left Ventricular Meridional End Systolic Stress (LVMESS) Interrelationship In Middle- Aged And Elderly Obese Subject With Type 2 Di... by Akeel AMH Zwain, Amina A. Al-Dijaili, Khalid Amber

“…LVMESS and IGF-1 levels were compared between groups; group differences were analyzed using unpaired t test and linear correlation test. Data were expressed as the mean ± S.D, using SPSS version 18). …”
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Treating sleep problems in young people at ultra-high-risk of psychosis: study protocol for a single-blind parallel group randomised controlled feasibility trial (SleepWell) by Apostolos Tsiachristas, Daniel Freeman, Thomas Kabir, Felicity Waite, Louise Johns, Jill Mollison, Ariane Petit, Emma Černis, Daniel Maughan

“…We collected initial case series data with 12 young people at ultra-high-risk of psychosis. …”
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Serum <i>P</i>-Cresyl Sulfate Levels Correlate with Peripheral Arterial Disease in Hypertensive Patients by Yahn-Bor Chern, Jen-Pi Tsai, Bang-Gee Hsu, Chin-Hung Liu, Ji-Hung Wang

“…<b>Background/Objectives:</b> <i>p</i>-Cresyl sulfate (PCS) is implicated in inflammation, oxidative stress and vascular dysfunction. …”
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Placental growth factor exerts modulatory effects on in vitro activated T cells by E. A. Smetanenko, O. Yu. Leplina, M. A. Tikhonova, N. M. Pasman, A. A. Ostanin, E. R. Chernykh

“…Given the elevated levels of PlGF in successful pregnancy and its decrease in gestation complications, the obtained data also suggest that PlGF-mediated suppression may be implicated into the governing immune evasion in pregnancy.…”
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Identification and characterization of Faecalibacterium prophages rich in diversity-generating retroelements by Anastasia Gulyaeva, Lei Liu, Sanzhima Garmaeva, Marloes Kruk, Rinse K. Weersma, Hermie J. M. Harmsen, Alexandra Zhernakova

“…We further note that four of the prophages possess diversity-generating retroelements implicated in rapid mutation of phage genome loci associated with phage–host and phage–environment interactions and analyze the intricate patterns of retroelement activity. …”
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Stream‐breeding salamander use of headwater stream networks in managed forests of western Washington, USA by Reed Ojala‐Barbour, Aimee P. McIntyre, Eric M. Lund, Marc P. Hayes

“…We also evaluated salamander relative abundance and two hydrologic characteristics, dry channel and seeps. We analysed data collected in 2006 and 2007 from 17 amphibian‐occupied, non‐fish‐bearing basins in Western Washington with managed forest ages 30–80. …”
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Prognostic value of baseline glucose levels for mortality in patients with cardiogenic shock: a systematic review and meta-analysis by Lisha Wu, Jingjing Cao, Jiuxin Ge

“…Abstract Background Baseline glucose levels have been implicated in the prognosis of critically ill patients. …”
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Hyperuricaemia elevates risk of short-term readmission and mortality in patients with heart failure by Haibo Chen, Wei Wen, Jiahuan Rao, Ruihui Lai, Lingyan Jiang

“…Serum uric acid (SUA), a product of purine metabolism, has been implicated in HF progression. However, the association between hyperuricaemia and the short-term readmission and mortality in patients with HF remains controversial.Methods In this retrospective cohort study, we analysed data from a HF database specific to the Chinese population. …”
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Disease burden of oesophageal cancer attributable to genetic variants and alcohol consumption in Hong Kong, China by Xuechen Xiong, Carmen Ng, Zhentong Peng, Jianchao Quan

“…Interpretation: This study implicates the importance of implementing a tailored oesophageal cancer screening program for individuals with the ALDH2*2 genotype in East Asia, emphasizing its importance for public health and policy. …”
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