Sex-specific association between serum α-klotho levels and sleep disturbances in the elderly: a cross-sectional study by Lu Liu, Tao Xu, Xiaolan Gao, Xianying Lei, Qinxue Hu

“…Methods This study utilized data from the National Health and Nutrition Examination Survey (NHANES) to initially investigate the association between α-klotho levels and SD, with analyses conducted separately for both sexes. …”
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On the Origins of Coronal Alfvénic Waves by Richard J. Morton, Roberto Soler

“…We present an investigation of the Alfvénic wave power spectrum in the Sun’s corona, obtained from observations with DKIST Cryo-NIRSP. The data provide unprecedented temporal resolution and signal-to-noise ratio, revealing a detailed power spectrum out to frequencies exceeding 10 mHz. …”
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ITGAV as a promising diagnostic, immunological, and prognostic biomarker in pan-cancer by Hanyang Su, Jie Wang, Xinyu Cao, Xiangqian Zhang, Huajun Zhang, Xiaojin Liu

“…We conducted an integrative pan-cancer analysis of ITGAV using data from TCGA, GTEx, CCLE, and other public databases. …”
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CEBPB dampens the cuproptosis sensitivity of colorectal cancer cells by facilitating the PI3K/AKT/mTOR signaling pathway by Tianchen Huang, Yong Zhang, Yachao Wu, Xiaodong Han, Lei Li, Zhipeng Guo, Kan Li, Yanshan Xin, Weijie Wang

“…CEBPB was strongly implicated in copper ion homeostasis and the mTOR signaling pathway in CRC. …”
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Retinoid X receptor γ predicts the prognosis and is associated with immune infiltration in kidney renal clear cell carcinoma: a qRT-PCR, TCGA and in silico research by Jianda Dong, Lailai Fan, Qiaolin Wu, Zhouci Zheng

“…While Retinoid X receptor γ (RXRG) has been implicated in various diseases and human cancers, its specific role in KIRC remains undetermined. …”
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MiRNA-Related SNPs and Risk of Esophageal Adenocarcinoma and Barrett's Esophagus: Post Genome-Wide Association Analysis in the BEACON Consortium. by Matthew F Buas, Lynn Onstad, David M Levine, Harvey A Risch, Wong-Ho Chow, Geoffrey Liu, Rebecca C Fitzgerald, Leslie Bernstein, Weimin Ye, Nigel C Bird, Yvonne Romero, Alan G Casson, Douglas A Corley, Nicholas J Shaheen, Anna H Wu, Marilie D Gammon, Brian J Reid, Laura J Hardie, Ulrike Peters, David C Whiteman, Thomas L Vaughan

“…Multiple risk factors have been identified for EA and its precursor, Barrett's esophagus (BE), such as reflux, European ancestry, male sex, obesity, and tobacco smoking, and several germline genetic variants were recently associated with disease risk. Using data from the Barrett's and Esophageal Adenocarcinoma Consortium (BEACON) genome-wide association study (GWAS) of 2,515 EA cases, 3,295 BE cases, and 3,207 controls, we examined single nucleotide polymorphisms (SNPs) that potentially affect the biogenesis or biological activity of microRNAs (miRNAs), small non-coding RNAs implicated in post-transcriptional gene regulation, and deregulated in many cancers, including EA. …”
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Growth arrest-specific transcript 5 associated snoRNA levels are related to p53 expression and DNA damage in colorectal cancer. by Jonathan Krell, Adam E Frampton, Reza Mirnezami, Victoria Harding, Alex De Giorgio, Laura Roca Alonso, Patrizia Cohen, Silvia Ottaviani, Teresa Colombo, Jimmy Jacob, Loredana Pellegrino, Gordon Buchanan, Justin Stebbing, Leandro Castellano

“…<h4>Background</h4>The growth arrest-specific transcript 5 gene (GAS5) encodes a long noncoding RNA (lncRNA) and hosts a number of small nucleolar RNAs (snoRNAs) that have recently been implicated in multiple cellular processes and cancer. …”
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Hemoglobin A1c and arterial and ventricular stiffness in older adults. by Susan J Zieman, Aruna Kamineni, Joachim H Ix, Joshua Barzilay, Luc Djoussé, Jorge R Kizer, Mary L Biggs, Ian H de Boer, Michel Chonchol, John S Gottdiener, Elizabeth Selvin, Anne B Newman, Lewis H Kuller, David S Siscovick, Kenneth J Mukamal

“…We performed cross-sectional analyses using baseline exam data including echocardiography, ankle and brachial blood pressure measurement, and carotid ultrasonography. …”
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When the bite is not the threat: non-venomous snakebites and their impact on rural child health by Kavinda Dayasiri, Achila Ranasinghe, Nayani Suraweera, Priyanga Burhan

“…Children aged 0–17 years with confirmed bites from snakes of low or no medical significance were included. Data were collected through medical records and caregiver interviews. …”
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Acute Respiratory Tract Infection and Sudden Sensorineural Hearing Loss: A Multinational Cohort Study by Chien-Hsiang Weng, Jun-Fu Lin, Jing-Jie Wang

“…<b>Methods:</b> We conducted a multinational retrospective cohort study using data from the TriNetX Global Collaborative Network. …”
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Characterizing the regulatory effects of H2A.Z and SWR1-C on gene expression during hydroxyurea exposure in Saccharomyces cerevisiae. by Hilary T Brewis, Peter C Stirling, Michael S Kobor

“…While H2A.Z has often been implicated in transcription regulation, htz1Δ mutants exhibit minimal changes in gene expression compared to wild-type. …”
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Functional MRI-based study of emotional experience in patients with psychogenic non-epileptic seizures: Protocol for an observational case-control study-EMOCRISES study. by Pierre Fauvé, Louise Tyvaert, Cyril Husson, Emmanuelle Hologne, Xiaoqing Gao, Louis Maillard, Raymund Schwan, Claire Banasiak, Wissam El-Hage, Gabriela Hossu, Coraline Hingray

“…In this study, we plan to obtain new data comparing functional brain activity of participants suffering from PNES, from PTSD and healthy controls via functional brain MRI during resting state and under emotional visual stimulation. …”
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Epigenetic regulation of individual components of combined hepatocellular-cholangiocarcinoma. by Kyle M Schachtschneider, Luke N Redlon, Ryan Peter Lokken, Yu-Hui Huang, Grace Guzman, Lawrence B Schook, Ron C Gaba

“…Finally, increased expression of several genes previously implicated in tumor aggressiveness, prognosis, and treatment responses were identified. …”
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Characterization of Somatic Mutations in Malaysian Luminal Breast Cancer by Yock Ping Chow, Ryia Illani Mohd Yunos, Isa Mohd Rose, Norlia Abdullah, Rohaizak Muhammad, Shahrun Niza Abdullah Suhaimi, Saladina Jaszle Jasmin, Norshahidah Mahamad Nadzir, Nurul-Syakima Ab Mutalib, Rahman Jamal

“…Despite thousands of breast tumour samples have been sequenced, there is no data yet on Malaysian patients. Therefore, it is clinically important to identify actionable mutated genes or pathways implicated in our local breast cancer patients to establish a more defined framework for precision medicine and clinical trials. …”
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Development and validation of the gift reciprocation anxiety scale (GRAS) for youths and adults in intimate relationships by Mohd. Ashik Shahrier, Shakira Khatun

“…Next, the adequacy of the data for factor analysis was checked and exploratory factor analysis (EFA) was done, extracting a single factor structure which was confirmed through the same factor retention using parallel analysis (PA). …”
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Ethnobotanical Study of Rattans on Suku Anak Dalam Community in Bukit Duabelas Nasional Park by Dwi Mairida, Muhadiono Muhadiono, Iwan Hilwan

“…This research attempts to investigate the species of rattans utilized and to analyze the local wisdom of Suku Anak Dalam(SAD) community.The data was collected by doing an interview the informants consisting of temenggung (head of the tribe), jenang (the liaison between the villagers and anak dalam), rattans gatherers, induk (mother) and hand maker. …”
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Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells. by James Pritchett, Varinder S Athwal, Emma Harvey, Katherine Martin, Jessica Llewellyn, Philip Ireland, Alexander Nicolaides, Martin J Humphries, Nicoletta Bobola, Neil A Hanley, Karen Piper Hanley

“…<h4>Conclusion</h4>These data provide evidence for EPIM and SOX9 functioning by mutual negative feedback to regulate attributes of the quiescent or activated state of HSCs. …”
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Endoplasmic reticulum stress activates the hepatic activator protein 1 complex via mitogen activated protein kinase-dependent signaling pathways. by Shantel Olivares, Richard M Green, Anne S Henkel

“…ER stress-induced activation of Fos-related components is dependent primarily on ERK activation whereas ER stress-induced activation of Jun-related components is dependent primarily on JNK activation, although there is interplay between these regulatory pathways. These data implicate a novel signaling pathway by which sustained ER stress, as observed in many chronic liver diseases, may promote hepatic carcinogenesis.…”
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Interleukin-6 as a Predictive Marker for Lymph Node and Distant Metastasis in Colorectal Cancer: A Retrospective Cohort Study by Xiao J, Tian M, Chen G, Li H

“…While interleukin-6 (IL-6), a key inflammatory cytokine, is implicated in tumor metastasis, its specific association with lymph node metastasis (LNM) and distant metastasis (DM) in CRC remains unclear.Methods: We retrospectively analyzed clinical data and serum levels of carcinoembryonic antigen (CEA) and cytokines (including IL-6) in 427 CRC patients, stratified by metastatic status. …”
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The role of epigenetic modification in tumorigenesis and progression of pituitary adenomas: a systematic review of the literature. by Matthew Pease, Chao Ling, William J Mack, Kai Wang, Gabriel Zada

“…Data regarding histopathological subtype, target genes, mode of epigenetic modification, and clinical correlation were recorded and analyzed.…”
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