Methanogenesis marker 16 metalloprotein is the primary coenzyme M synthase in Methanosarcina acetivorans. by Grayson L Chadwick, Madison C Williams, Katie E Shalvarjian, Dipti D Nayak

“…Additionally, the ∆ MMP16 mutant is a CoM auxotroph in sulfide-free medium. These data reinforce prior claims that MMP16 is a bona fide ComF but point to backup pathway(s) that can conditionally compensate for its absence. …”
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CCR2 restricts IFN-γ production by hippocampal CD8 TRM cells that impair learning and memory during recovery from WNV encephalitis by Shenjian Ai, Artem Arutyunov, Joshua Liu, Jeremy D. Hill, Xiaoping Jiang, Robyn S. Klein

“…Consistent with this, WNV-recovered Cd8a cre Ccr2 fl/fl mice exhibit decreased recognition memory. Overall, these data implicate CCR2 signaling in the regulation of CD8 TRM phenotype, including antiviral specificity and IFN-γ expression, highlighing a neuroprotective role for CCR2 in limiting CD8 T cell-mediated neuroinflammation and cognitive deficits, providing insights into potential therapeutic targets for CNS infections.…”
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A Machine Learning Approach to Identifying Risk Factors for Long COVID-19 by Rhea Machado, Reshen Soorinarain Dodhy, Atharve Sehgal, Kate Rattigan, Aparna Lalwani, David Waynforth

“…Given the large number and variety of predictors implicated spanning health-related and sociodemographic factors, machine learning becomes a valuable tool. …”
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Credit Risk Management Practices and Loan Performance of Commercial Banks in Uganda by Agaba, Francis, Tamwesigire, Caleb, Eton, Marus

“…The study used a structured questionnaire to collect numerical data from the credit staff and management of 19 commercial banks. …”
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Credit Risk Management Practices and Loan Performance of Commercial Banks in Uganda by Francis, Agaba, Caleb, Tamwesigire, Eton, Marus

“…The study used a structured questionnaire to collect numerical data from the credit staff and management of 19 commercial banks. …”
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Early-life tobacco smoke elevating later-life osteoporosis risk: Mediated by telomere length and interplayed with genetic predisposition by Dongsheng Di, Haolong Zhou, Zhangbo Cui, Jianli Zhang, Qian Liu, Tingting Yuan, Tingting Zhou, Xiao Luo, Danyang Ling, Qi Wang

“…The mediating role of telomere length (TL) and the interaction with genetic predisposition were also studied. Methods: Data on in utero tobacco smoke exposure (IUTSE) status and age of tobacco use initiation from the UK Biobank were used to estimate early-life tobacco smoke exposure. …”
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Causal role of the gut microbiome in certain human diseases: a narrative review by Jesse Papenburg, Bertrand Routy, Todd C Lee, Matthew P Cheng, Hao Shi, Cedric P Yansouni, Alexander Lawandi, Connor Prosty, Khaled Katergi, Philip Burnham, Lee Swem

“…Through observational and preclinical data, the gut microbiome has been implicated in the pathogenesis of a spectrum of chronic diseases ranging from psychiatric to gastrointestinal in nature. …”
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Characterization of Novel WFS1 Variants in Three Diabetes Pedigrees by ChangQing Liu, HangYu Fang, Dong Wang, YiPing Cheng, Ping Shi, ChunXiao Yu, XiaoHong Li, Hui Zhao, Wei Hou, ZhenKui Guo, Chao Xu, QingBo Guan

“…ABSTRACT Background Mutations in the WFS1 gene are implicated in Wolfram syndrome (WS), Wolfram‐like syndrome (WFLS), and maturity‐onset diabetes of the young (MODY). …”
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TREM2+ macrophages: a key role in disease development by Xinxin Wang, Yunhan Wang, Lei Yang, Lei Yang, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang, Yi Zhang, Li Yang, Li Yang, Li Yang

“…This review aims to highlight the pivotal role of TREM2 in macrophages and immune-related diseases, elucidate its underlying mechanisms of action, explore its potential as a clinical diagnostic and prognostic marker, and propose therapeutic strategies targeting TREM2 based on current clinical trial data, providing comprehensive guidance and references for clinical practice.…”
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Re-localization of a repeat-containing fungal effector by apoplastic protein Chitinase-like 1 blocks its toxicity by Hanqiao Liu, Wenshu Zhang, Qinqfei He, Reyila Aikemu, Huijuan Xu, Zhan Guo, Lu Wang, Weixi Li, Guilin Wang, Xinyu Wang, Wangzhen Guo

“…Our data demonstrates that genetic manipulation of effector target constitutes potential strategy for improving crop resistance to fungal pathogens.…”
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SUDEP risk is influenced by longevity genomics: a polygenic risk score studyResearch in context by Helena Martins, James D. Mills, Susanna Pagni, Medine I. Gulcebi, Angeliki Vakrinou, Patrick B. Moloney, Lisa M. Clayton, Ravishankara Bellampalli, Hannah Stamberger, Sarah Weckhuysen, Pasquale Striano, Federico Zara, Richard D. Bagnall, Rebekah V. Harris, Kate M. Lawrence, Lynette G. Sadleir, Douglas E. Crompton, Daniel Friedman, Juliana Laze, Ling Li, Samuel F. Berkovic, Christopher Semsarian, Ingrid E. Scheffer, Orrin Devinsky, Karoline Kuchenbaecker, Simona Balestrini, Sanjay M. Sisodiya

“…We hypothesised that common genetic variation contributes to SUDEP risk. Methods: Genetic data from people who had succumbed to SUDEP was compared to data from people with epilepsy who had not succumbed to SUDEP and from healthy controls. …”
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Developing Security Consciousness among Nigerian Youths: Do Self-Esteem and Self-Awareness Matter? by Kalu Ogba, Peter Labe Atime, Fredrick O. Onyia, Orkuma Anyoko-shaba, Igwe Chukwuemeka Obasi, Bassey Ubong Ibongudo

“…Although there is a growing need for sustained safety, little research implicates the youth who have been found to be at the heart of insecurity. …”
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Dynamic regulation of Rgs16 and its correlation with Neuregulin1 expression in acute and chronic nerve injury by Marina García-Bejarano, Marina García-Bejarano, Marina García-Bejarano, Riccardo Aucello, Riccardo Aucello, Federica Zen, Federica Zen, Marwa El Soury, Marwa El Soury, Francesca Cordero, Jesús M. de la Fuente, Isabelle Perroteau, Giulia Ronchi, Giulia Ronchi, Giovanna Gambarotta, Giovanna Gambarotta

“…Analysis of publicly available RNA sequencing data from sciatic nerves of wild-type and CMT1A rats during development showed a significant upregulation of Rgs16 in transgenic rats at P18. …”
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MicroRNA in Sjögren’s Syndrome: Their Potential Roles in Pathogenesis and Diagnosis by M. Reale, C. D’Angelo, E. Costantini, M. Laus, A. Moretti, A. Croce

“…The purpose of this work is to gather the data present in the literature to clarify this complex topic.…”
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A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment. by Mette Nyegaard, Nanna D Rendtorff, Morten S Nielsen, Thomas J Corydon, Ditte Demontis, Anna Starnawska, Anne Hedemand, Annalisa Buniello, Francesco Niola, Michael T Overgaard, Suzanne M Leal, Wasim Ahmad, Friedrik P Wikman, Kirsten B Petersen, Dorthe G Crüger, Jaap Oostrik, Hannie Kremer, Niels Tommerup, Morten Frödin, Karen P Steel, Lisbeth Tranebjærg, Anders D Børglum

“…In conclusion, we have identified a new DFNA locus located on chromosome 6q15-21 and implicated CD164 as a novel gene for hearing impairment.…”
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Development of Women Resilience in the Workplace: A Solution to Break the Glass Ceiling by Farajallah Rahimi, Maral Ahmadi Arpanahi

“…MethodologyThis research is applied in terms of purpose and based on the method of data collection in the category of descriptive-correlational research. …”
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Improving health-promoting workplaces through interdisciplinary approaches. The example of WISEWORK-C, a cluster of five work and health projects within Horizon-Europe by Deborah De Moortel, Michelle C Turner, Ella Arensman, Alex Binh Vinh Duc Nguyen, Víctor Gonzalez

“…European Commission. (2022). The possible implications of the green transition for the EU labour market (Discussion Paper 176). …”
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Assessing the role of volumetric brain information in multiple sclerosis progression by Andy A. Shen, Aidan McLoughlin, Zoe Vernon, Jonathan Lin, Richard A.D. Carano, Peter J. Bickel, Zhuang Song, Haiyan Huang

“…Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions. …”
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Overexpression of the ferroptosis-related gene, NFS1, corresponds to gastric cancer growth and tumor immune infiltration by Mao Zhiyun, Shi Zhongmei, Cui Ming, Ma Xiaohong, Wang Yan, Zhang Xiaojie, Jing Rongrong, Wang Jingchun

“…Transcriptomic data from TCGA and GTEX were analyzed to assess mRNA expression and survival correlation with NFS1 among GC patients. …”
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Enhancer RNA transcription pinpoints functional genetic variants linked to asthma by Sarah K. Sasse, Amber Dahlin, Lynn Sanford, Margaret A. Gruca, Arnav Gupta, Fabienne Gally, Ann Chen Wu, Carlos Iribarren, Robin D. Dowell, Scott T. Weiss, Anthony N. Gerber

“…The role of rs258760 as a protective variant for asthma was independently validated using UK Biobank data. Our findings establish eRNA signatures as a tool for discovery of functional genetic variants and define a novel association between air pollution, glucocorticoid signaling and asthma.…”
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