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14961
Liver cancer-specific prognostic model developed using endoplasmic reticulum stress-related LncRNAs and LINC01011 as a potential therapeutic target
Published 2025-04-01“…Here, we analyzed RNA and clinical data from the Cancer Genome Atlas and sourced ERS-related genes from the Molecular Signatures Database. …”
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14962
Leveraging modern technologies in agriculture: Recent progress and prospects in Bangladesh
Published 2025-04-01“…The study discusses the current implication of precision agriculture, Internet of Things (IoT) based monitoring systems, automated irrigation, smart seed selection, and eco-friendly farming techniques. …”
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14963
SHINE study: Developing an intervention for safe hospital insulin use for older or frail adults with diabetes undergoing surgical hospital admission: Study protocol.
Published 2024-01-01“…We will utilise their experiences and perspectives to establish priorities and generate ideas for the development of a conceptual model aimed at supporting the insulin safety review process in hospitals. Data will be analysed using framework analysis. People with diabetes were involved in the design of this study. …”
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14964
Are payment methods for prescription drugs associated with polypharmacy in older adults in Ireland? Evidence from the TILDA cohort study
Published 2020-10-01“…We sought to examine the relationship between polypharmacy and payment methods for prescription drugs among older adults in Ireland.Methods This is a cross-sectional analysis of data from wave 3 of The Irish Longitudinal Study on Aging, a nationally representative cohort study sample of community-living adults aged 50 years and older in Ireland. …”
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14965
Synaptojanin1 is required for temporal fidelity of synaptic transmission in hair cells.
Published 2009-05-01“…Synaptojanin has been previously implicated in SV recycling; therefore, we tested synaptic transmission at hair-cell synapses. …”
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14966
The use of technology to scientific reasoning in science education: A bibliometric and content analysis of research papers
Published 2025-01-01“…Achievement tests are the predominant data collection method, often complemented by observations and surveys for comprehensive insights. …”
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14967
Duchenne muscular dystrophy gene product expression is associated with survival in head and neck squamous cell carcinoma
Published 2025-03-01“…Abstract Mutation of the Duchenne muscular dystrophy (DMD) gene causes neuromuscular disorders, but increasing evidence has implicated DMD in the development and progression of several major cancer types. …”
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14968
Diversity and Conservation Knowledge of Chondrichthyans in Northern Coastal Areas of Central Java
Published 2018-08-01“…Samples were collected in fish capture household places in Tegal, Pemalang, Pekalongan, Semarang, Pati, and identified in Animal Taxonomy Laboratory of Biology Department, Universitas Negeri Semarang. Data were analyzed using descriptive qualitative based on the morphology characteristic. …”
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14969
Allosteric Regulation of Fibronectin/α5β1 Interaction by Fibronectin-Binding MSCRAMMs.
Published 2016-01-01“…Detailed kinetic analysis of these interactions reveal that this change in affinity can be attributed solely to an increase in the initial Fn/α5β1 on-rate and that this rate-enhancement is dependent on high-affinity Fn-binding by MSCRAMMs. These data implicate MSCRAMM-induced perturbation of specific intramolecular contacts within the Fn heterodimer resulting in activation by exposing previously cryptic α5β1 interaction motifs. …”
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14970
Causal association between cathepsins and asthma: a Mendelian randomization study
Published 2025-07-01“…Cathepsins, a group of proteolytic enzymes, have recently been implicated in asthma pathophysiology, though their exact causal role remains unclear. …”
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14971
Association of plasminogen activator inhibitor-type 1 (-675 4G/5G) polymorphism with pre-eclampsia: systematic review.
Published 2013-01-01“…<h4>Background and aims</h4>Excessive generation of plasminogen activator inhibitor-type 1 (PAI-1) is implicated in the pathogenesis of pre-eclampsia and related conditions. …”
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14972
Descriptive transcriptome analysis of tendon derived fibroblasts following in-vitro exposure to advanced glycation end products.
Published 2022-01-01“…Specifically, pathways related to cell cycle progression and extracellular matrix remodeling were affected in our data set and may play a contributing role in the development of diabetic tendon complications.…”
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14973
Sex-dependent effects of Setd1a haploinsufficiency on development and adult behaviour.
Published 2024-01-01“…Loss of function (LoF) mutations affecting the histone methyl transferase SETD1A are implicated in the aetiology of a range of neurodevelopmental disorders including schizophrenia. …”
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14974
Evaluation of the CIPP Model of The Sewing Training Program
Published 2024-09-01“…The research used a descriptive qualitative approach and the research data was obtained through observation of training activities, interviews with organisers, instructors and trainees, and documentation from institutional profile books, institutional websites and photographs of training activities. …”
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14975
DksA-dependent regulation of RpoS contributes to Borrelia burgdorferi tick-borne transmission and mammalian infectivity.
Published 2021-02-01“…Subsequent transcriptomic and western blot assays indicate DksA regulates the expression of BBD18, a protein previously implicated in the post-transcriptional regulation of RpoS. …”
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14976
BREEDING POPULATIONS OF CULICINES WITHIN THE PERI-DOMESTIC ENVIRONMENT OF SOME COMMUNITIES IN ANAMBRA STATE, SOUTHEAST, NIGERIA
Published 2025-02-01“…Disposable plastic pipettes of 1.5ml capacity were used to aspirate immature stages of mosquitoes from plant axils. Data was analyzed using SPSS version 21.0. A total of 3,225 mosquito larvae/pupae were collected during the study. …”
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14977
Prediction of suicidal ideation and attempt in 9 and 10 year-old children using transdiagnostic risk features.
Published 2021-01-01“…This case-control analysis utilized baseline data from the Adolescent Brain and Cognitive Development (ABCD) Study, collected from 21 research sites across the United States (N = 11,369). …”
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14978
In Silico Network Toxicology, Molecular Docking, and Multi‐Level Bioinformatics Reveal Methyl Eugenol‐Induced Hepatocellular Carcinoma Mechanisms in Humans
Published 2025-05-01“…KEGG pathway enrichment further implicated metabolic pathways in ME‐induced HCC development. …”
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14979
Neuronal Deletion of <i>Tumor Susceptibility Gene 101</i> (<i>Tsg101</i>) Causes Rapid Apoptotic Loss of Hippocampal CA3 Neurons
Published 2025-05-01“…TSG101-dependent trafficking has been implicated in the propagation and spread of misfolded proteins associated with neurodegenerative diseases. …”
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14980
Airway epithelial specific deletion of Jun-N-terminal kinase 1 attenuates pulmonary fibrosis in two independent mouse models.
Published 2020-01-01“…The stress-induced kinase, c-Jun-N-terminal kinase 1 (JNK1) has previously been implicated in the pathogenesis of lung fibrosis. However, the exact cell type(s) wherein JNK1 exerts its pro-fibrotic role(s) remained enigmatic. …”
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