Integrating The Local Wisdom of Bulusan Kudus Into A P5 E-Module : A Feasibility and Practicality Study for Elementary School Students by Ika Ari Pratiwi, Tauffiqul Lutfiyah, Much Arsyad Fardani

“…The research used validation questionnaires to assess the feasibility of content (material) and media (design), as well as response questionnaires to gather feedback from both students and teachers. Data analysis techniques employed descriptive and qualitative methods. …”
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Evaluation of Quality of Root Canal Obturation, Coronal Restoration and Periapical Health in Failed Endodontically Treated Teeth by Syed Adeel Ahmed, Safia Anwar, Imtiaz ul Haq

“… Objective: To investigate the implication of quality of obturation and coronal restoration on periapical tissue in failed endodontically treated teeth. …”
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A Systematic Review of the Incidence, Risk Factors and Case Fatality Rates of Invasive Nontyphoidal Salmonella (iNTS) Disease in Africa (1966 to 2014). by Ifeanyi Valentine Uche, Calman A MacLennan, Allan Saul

“…Salmonella Typhimurium and Enteritidis are the major serovars implicated and together have been responsible for 91%% of the cases of iNTS disease, (where serotype was determined), reported in Africa. …”
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ARF6-dependent regulation of P2Y receptor traffic and function in human platelets. by Venkateswarlu Kanamarlapudi, Sian E Owens, Keya Saha, Robert J Pope, Stuart J Mundell

“…Furthermore, we demonstrate that Nm23-H1, a nucleoside diphosphate (NDP) kinase regulated by ARF6 which facilitates dynamin-dependent fission of coated vesicles during endocytosis, is also required for P2Y purinoceptor internalization. These data describe a novel function of ARF6 in the internalization of P2Y purinoceptors and demonstrate the integral importance of this small GTPase upon platelet ADP receptor function.…”
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A paradoxical population structure of var DBLα types in Africa. by Mun Hua Tan, Kathryn E Tiedje, Qian Feng, Qi Zhan, Mercedes Pascual, Heejung Shim, Yao-Ban Chan, Karen P Day

“…By applying a novel ups classification algorithm (cUps) to publicly-available DBLα sequence datasets, we categorised DBLα according to association with the three ups groups, thereby avoiding the need to sequence complete genes. Data from deep sequencing of DBLα types in a local population in northern Ghana surveyed seven times from 2012 to 2017 found variants with rare-to-moderate-to-extreme frequencies, and the common variants were temporally stable in this local endemic area. …”
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Integrated Computational Approach to Rational Drug Design Targeting SIK2/3: From Theory to Practice by Eid Youssef Eid Rashed, Alisa Gorislav

“…Through a rigorous analysis of generated data and molecular docking simulations, we successfully identified lead compounds with promising therapeutic potential. …”
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Using multivariable Mendelian randomization to disentangle the causal effects of lipid fractions. by Stephen Burgess, Daniel F Freitag, Hassan Khan, Donal N Gorman, Simon G Thompson

“…We employ this approach using published data on 185 lipid-related genetic variants and their associations with lipid fractions in 188,578 participants, and with CAD risk in 22,233 cases and 64,762 controls. …”
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How Organizational Culture Moderate the Effect of Total Productive Maintenance Practice on Organization’s Operational Performance? Evidences from Indonesian Mining Industry by Nasar Buntu Laulita, Agustinus Setyawan

“…The research type was under explanative research with hypothesis testing from primary data that was obtained from distributing questionnaires and direct interviews in the field which was analyzed by using Lisrel 8.7. …”
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Detection of Hepatocellular Carcinoma Using Optimized miRNA Combinations and Interpretable Machine Learning Models by Zhengwu Long, Lisheng Zhang

“…In this study, we developed an interpretable machine learning (ML) model for HCC prediction using miRNA-seq data from TCGA-LIHC. Five feature selection algorithms and 11 classifiers were employed to identify key miRNAs for HCC diagnosis, with the Sarsa-CatBoost combination yielding the best performance, achieving an accuracy of 96.0%, a matthews correlation coefficient of 89.2%, and an AUC of 97.6%. …”
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Feasibility Analysis of Organic Rice Cultivation Business in Semarang City by Etty Soesilowati, Nana Kariada Tri Martuti, Dhita Prasisca Mutiatari

“…The variables studied include the amount of immersed investment, cash flow, total costs required and net income in one planting period. The data were collected through observation techniques, questionnaires, and interviews. …”
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Serine Phosphorylation of HIV-1 Vpu and Its Binding to Tetherin Regulates Interaction with Clathrin Adaptors. by Tonya Kueck, Toshana L Foster, Julia Weinelt, Jonathan C Sumner, Suzanne Pickering, Stuart J D Neil

“…Importantly, it also requires the Vpu phosphoserine motif and adjacent acidic residues. Taken together these data explain the discordance between the role of SCFβTRCP1/2 and Vpu phosphorylation in tetherin antagonism, and indicate that phosphorylation of Vpu in Vpu/tetherin complexes regulates promiscuous recruitment of adaptors, implicating clathrin-dependent sorting as an essential first step in tetherin antagonism.…”
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Antibacterial susceptibility profile of Pseudomonas and related bacterial species associated with wound infections in Calabar, Nigeria by Ahaotu, C.E. , Ibeneme, E.O. , *, Utsalo, S.J.

“…IBM SPSS version 20.0 was utilized for statistical analysis of data obtained and statistical significance was drawn at p≤0.05. …”
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Maic Audo Lin Sihombing by Maic Audo Lin Sihombing, Sutiman B. Sumitro, Muhaimin Rifa'i

“…Chronic inflammation is implicated in β-cell damage and function and promotes apoptosis. …”
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LOTS and HOTS reading questions in EFL textbooks (Kurikulum Merdeka): unveiling every learning process purposes by Maria Kartika Widiastuti, Concilianus Laos Mbato

“…Secondly, the research explored the implication of EFL Senior High School Texbooks’ (Kurikulum Merdeka) different characteristics represented in Bloom’s Taxonomy reading comprehension questions pattern. …”
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Neurocognitive dynamics and behavioral differences of symmetry and asymmetry processing in working memory: insights from fNIRS by Izabela Maria Sztuka, Simone Kühn

“…This effect varies with the type of symmetry, with diagonal symmetry being the most effective. Neuroimaging data showed distinct brain activation patterns when participants processed symmetrical stimuli, particularly in the memory-straining condition. …”
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Role of selenium in the pathophysiology of cardiorenal anaemia syndrome by Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata

“…Among the micronutrients (trace elements) that are essential to humans, inadequate iron status has previously been implicated in the pathogenesis of CRAS; however, the roles of other trace elements remain unclear. …”
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Arginylation-dependent neural crest cell migration is essential for mouse development. by Satoshi Kurosaka, N Adrian Leu, Fangliang Zhang, Ralph Bunte, Sougata Saha, Junling Wang, Caiying Guo, Wei He, Anna Kashina

“…Recent studies of protein arginylation implicated this poorly understood posttranslational modification in the functioning of actin cytoskeleton and in cell migration in culture. …”
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CRISPR-Mediated Triple Knockout of SLAMF1, SLAMF5 and SLAMF6 Supports Positive Signaling Roles in NKT Cell Development. by Bonnie Huang, Julio Gomez-Rodriguez, Silvia Preite, Lisa J Garrett, Ursula L Harper, Pamela L Schwartzberg

“…However, the TKO worsened defects in iNKT cells development seen in SLAMF6 single gene-targeted mice, supporting data on positive signaling and potential redundancy between these receptors.…”
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T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degeneration. by Fernando Cruz-Guilloty, Ali M Saeed, Stephanie Duffort, Marisol Cano, Katayoon B Ebrahimi, Asha Ballmick, Yaohong Tan, Hua Wang, James M Laird, Robert G Salomon, James T Handa, Victor L Perez

“…Using a mouse model, we examined the relationship of two factors implicated in AMD development: oxidative stress and the immune system. …”
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Antimicrobial resistance profile among bacteria isolated from patients presenting with wounds at Kabale Regional Referral Hospital, South western Uganda by Andrew, Baguma, Benson, Musinguzi, Kagirita, Atek Atwiine, Joel, Bazira

“…Infected wounds are often associated with delayed epidermal maturation resulting into prolonged hospitalization. Data on profile of clinical significant bacteria and their respective antibiotic drug resistance in Uganda is still limited. …”
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