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    Common and rare variant analyses implicate late-infancy cerebellar development and immune genes in ADHD by Yuanxin Zhong, Larry W. Baum, Justin D. Tubbs, Rui Ye, Lu Hua Chen, Tian Wu, Se-Fong Hung, Chun-Pan Tang, Ting-Pong Ho, Robert Moyzis, James Swanson, Chi-Chiu Lee, Pak C. Sham, Patrick W. L. Leung

    Published 2025-06-01
    “…We employed various analytical methods at different levels, while also leveraging multi-omics data and large-scale summary statistics to comprehensively analyze the genetic basis of ADHD. …”
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  9. 1169

    Effects of chemoradiotherapy on surface PD-L1 expression in esophageal cancer and its implications for immunotherapy by Lovis Hampe, Stefan Küffer, Tim Niemeier, Niklas Christian Scheele, Laetitia Zoe Hampe, Anna Luisa Riedl, Laura Anna Fischer, David Alexander Ziegler, Martin Leu, Leif Hendrik Dröge, Alexander König, Michael Ghadimi, Friederike Braulke, Stefan Rieken, Hanibal Bohnenberger, Rami A. El Shafie

    Published 2024-12-01
    “…Measurement of PD-L1 kinetics revealed a transient upregulation of surface PD-L1, which peaked at 72 hours post-treatment and subsequently returned to baseline levels by 168 hours. In vivo, data demonstrated no significant PD-L1 expression changes when comparing pre- and post-treatment levels.ConclusionsChemotherapy, RT, and CRT can induce PD-L1 expression in various esophageal cancer cell lines. …”
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    Exploring CISD1 as a multifaceted biomarker in cancer: Implications for diagnosis, prognosis, and immunotherapeutic response by Caiyue Li, Zhipin Liang, Gabrielle Vontz, Connor Kent, Wenbo Ma, Lei Liu, Riya Dahal, Jovanny Zabaleta, Guoshuai Cai, Jia Zhou, Huangen Ding, Qiang Shen

    Published 2025-11-01
    “…We obtained and analyzed data from databases including TCGA, GTEx, THPA, GEPIA2.0, SangerBox, cBioPortal, TIMER2.0, CAMOIP, DAVID, SRPLOT, and TISIDB. …”
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  12. 1172

    Confirmatory Biopsy Outcomes in Patients with Grade Group 2 Prostate Cancer: Implications for Early Management by Riccardo Leni, Emily A. Vertosick, Nicole Liso, Oguz Akin, Sigrid V. Carlsson, Francesco Montorsi, Alberto Briganti, James A. Eastham, Samson W. Fine, Andrew J. Vickers, Behfar Ehdaie

    Published 2025-02-01
    “…Conclusions and clinical implications: Patients with GG 2 prostate cancer, no evidence of EPE, and a few millimeters of pattern 4 should undergo cBx before proceeding to surgery. …”
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    CAR T-cell therapy for systemic lupus erythematosus: current status and future perspectives by Jincai Zhou, Bixia Lei, Feifei Shi, Xinran Luo, Kai Wu, Yanhong Xu, Yuting Zhang, Rongjiao Liu, Huajing Wang, Joy Zhou, Xiaowen He

    Published 2024-12-01
    “…We also summarize clinical data on the safety and efficacy of anti-CD19 and anti-B cell maturation antigen (BCMA) CAR-T cells in targeting B-cells in SLE. …”
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  15. 1175

    Lessons from the Classroom: MEI for Data Scientists by Richard Freedman, Daniel Russo-Batterham

    Published 2025-02-01
    “…Many data science and computer science students today are familiar with JSON, and may even have worked with APIs to extract data from the web. …”
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    A Probabilistic Approach for Missing Data Imputation by Muhammed Nazmul Arefin, Abdul Kadar Muhammad Masum

    Published 2024-01-01
    “…This study contributes to the existing body of research on missing data imputation in big data analysis and offers practical implications for handling missing data in different datasets. …”
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  17. 1177

    Toward Utilizing Similarity in Hydrologic Data Assimilation by Haksu Lee, Haojing Shen, Yuqiong Liu

    Published 2024-10-01
    “…Finally, we discuss the implications, potential issues, and future challenges associated with utilizing similarity in hydrologic data assimilation.…”
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    Communicating clearly about data sharing in genomics by Donrich Thaldar, Diya Uberoi, Adrian Thorogood, Richard Milne, Ainsley J. Newson, Alison Hall, David Glazer, Paul Esselaar, Yann Joly

    Published 2025-07-01
    “…These definitions aim to improve communication within the genomics community by ensuring a consistent understanding of complex processes, addressing challenges like data localization and cross-border transfer. This article introduces these recently developed data sharing-related terms and considers their implications for data governance and global health research.…”
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    THE ROLE OF DATA VISUALIZATION IN ENHANCING TEXTUAL ANALYSIS by P. Milev

    Published 2023-12-01
    “…PURPOSE: The article aims to explore the integral role of data visualization in enhancing textual analysis, elucidating its current applications, ethical implications, challenges, and future trends. …”
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    Evaluating the Usability and Variability of Data on Transport for Modelling by WILFRED GORDIAN KAZAURA

    Published 2025-04-01
    “…Furthermore, the findings could have broader implications for other African cities facing similar data challenges, helping to advance data-driven approaches to transport planning across the continent. …”
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