Predicting complications in hypertensive disorders of pregnancy: external validation of a prognostic model for adverse perinatal outcomesAJOG Global Reports at a Glance by Klaartje M. Olde Loohuis, MD, Kim Luijken, MSc, PhD, Hannah Brown Amoakoh, MD, PhD, Kwame Adu-Bonsaffoh, MD, PhD, Diederick E. Grobbee, MD, PhD, FESC, Kerstin Klipstein-Grobusch, MSc PhD, Emmanuel Srofenyoh, MD, Mary Amoakoh-Coleman, MD, PhD, Joyce L. Browne, MD, PhD

“…Possible reasons include differences in case mix, clinical management strategies, or data collection procedures between development and validation settings; suboptimal modeling strategies at development; or omission of important predictors. …”
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Regulatory role of lnc-MAP3K13-3:1 on miR-6894-3p and SHROOM2 in modulating cellular dynamics in hepatocellular carcinoma by Kuai Chen, Manqin Zhu, Qinghua Hu, Hui Huang, Ka Chen, Xia Shuai, Jinshi Huang, Qiang Tao, Zhibin Guo

“…Consequently, identifying molecular targets that specifically inhibit the proliferation and metastasis of HCC cells is critical for improving treatment outcomes. Database analysis using Targetscan identified complementary binding sites for the human-specific miRNA hsa-miR-6894-3p (hereafter referred to as miR-6894-3p) on SHROOM2, and Starbase data suggested a potential regulatory interaction between lnc-MAP3K13-3:1 and miR-6894-3p in liver cancer. …”
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Key technologies for intelligent, efficient, and safe mining of impact thick coal seams due to hard roof by Bin YU, Xiangbin MENG, Yang TAI, Ziyu SHANG, Mingxian PENG, Tiejun KUANG, Feilong GUO, Dongyin LI, Shibo WANG

“…To address the challenges of source-based rock burst elimination and efficient mining in ultra-thick coal seams prone to rock bursts due to hard roofs, a safety assurance technology was developed to create a favorable environment for intelligent and efficient coal caving. …”
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Cardiotoxicity of Chemotherapeutic Drugs (Literature Review and Clinical Case Description) by Avagimyan Ashot A., Mkrtchyan Lusine G.

“…Materials and methods. We used content analysis, a method of system and comparative analysis, a bibliosemantic method for studying relevant scientific research on the topic of cardiotoxicity of chemotherapeutic drugs. …”
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Older Patients With Interstitial Lung Disease Feature a Distinct Clinical Profile by Laura Feltrer-Martínez, Sandra Orozco, Ana Alonso, Paloma Millan-Billi, Silvia Barril, Gisela Ruibal, Joel Francesqui, David Lobo-Prat, Ana Gimenez, Laura Lopez, Laura Martinez-Martinez, Ivan Castellvi, Diego Castillo

“…Patients over 64 years were selected. Data collection included diseases variables, diagnostic procedures and comorbidities. …”
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Minimizing competition by removing elephants from a degraded Ngulia rhino sanctuary, Kenya by Benson Okita-Ouma, Dominic Mijele, Rajan Amin, Francis Gakuya, David Ndeereh, Isaac Lekolool, Patrick Omondi, Daniel Woodley, Moses Litoroh, Juma Bakari, Richard Kock

“…Following concerns about the deteriorating vegetation condition in the sanctuary (fig. 1), detailed analysis of population data and assessment of habitat showed a 59% decline in the available rhino browse between 1991 and 2005 (rhino food plants i.e. below 2 m high) and 100% decline of browse material above 2 m height (fig. 2). …”
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Adherence to Life’s Essential 8 enhances gut microbiota diversity and cognitive performance by Yannick N. Wadop, Jazmyn Muhammad, Rebecca Bernal, Claudia L. Satizabal, Claudia L. Satizabal, Claudia L. Satizabal, Claudia L. Satizabal, Alexa Beiser, Alexa Beiser, Alexa Beiser, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramnik Xavier, Ramnik Xavier, Ramnik Xavier, Tiffany Kautz, Tiffany Kautz, Sudha Seshadri, Sudha Seshadri, Sudha Seshadri, Sudha Seshadri, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Bernard Fongang, Bernard Fongang, Bernard Fongang

“…MethodsIn this study, we analyzed data from 781 participants in the Framingham Heart Study (FHS) to explore the relationship between LE8 adherence, gut microbiota, and cognitive performance. …”
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Higher frequency of interstate over international transmission chains of SARS-CoV-2 virus at the Rio Grande do Sul - Brazil state borders by Filipe Zimmer Dezordi, José Valter Joaquim Silva Júnior, Terimar Facin Ruoso, Angela Giovana Batista, Pedro Mesquita Fonseca, Larissa Paim Bernardo, Richard Steiner Salvato, Tatiana Schäffer Gregianini, Thaísa Regina Rocha Lopes, Eduardo Furtado Flores, Rudi Weiblen, Patrícia Chaves Brites, Mônica de Medeiros Silva, João Batista Teixeira da Rocha, Gustavo de Lima Barbosa, Lais Ceschini Machado, Alexandre Freitas da Silva, Marcelo Henrique Santos Paiva, Matheus Filgueira Bezerra, Tulio de Lima Campos, Tiago Gräf, Daniel Angelo Sganzerla Graichen, Elgion Lucio da Silva Loreto, Gabriel da Luz Wallau

“…In summary, the retrospective analysis of genomic surveillance data demonstrated that virus transmission was less intense between country borders than within the country. …”
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A Systematic Assessment of <i>Leishmania donovani</i> Infection in Domestic and Wild Animal Reservoir Hosts of Zoonotic Visceral Leishmaniasis in India by Gajala Deethamvali Ghouse Peer, Anjali Priyadarshini, Archana Gupta, Arpana Vibhuti, Elcio Leal, Antonio Charlys da Costa, Carlos Prudencio, Kirtanjot Kaur, Saheem Ahmad, V. Samuel Raj, Ramendra Pati Pandey

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Use of sedative drugs in specialist palliative care (iSedPall): a multi-modal intervention pilot study protocol by Christoph Ostgathe, Claudia Bausewein, Eva Schildmann, Jeremias Bazata, Maria Heckel, Saskia Kauzner, Carsten Klein, Sabine H. Krauss, Alexander Kremling, Manuela Schneider, Andreas Seifert, Kerstin Ziegler, Christian Jäger, Jan Schildmann

“…Additionally, we aim to assess the feasibility of measuring healthcare professionals´ confidence in using sedative drugs as an outcome indicator for a possible subsequent study. Methods and analysis We will use a mixed-methods approach to develop and pilot a multi-modal intervention. …”
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EVALUATION OF THE EFFECTIVENESS OF TREATMENT OF CHRONIC CATARRHAL GINGIVITIS IN CHILDREN WITH DIABETES MELLITUS IN LONG-TERM OBSERVATIONS by L.F. Kaskova, V.A. Honcharenko

“…The combined use of CCG correction measures with antioxidant status ensured the stability of clinical outcomes, as evidenced by periodontal indexes data, and once again demonstrates the important role of oxidative stress in the development of periodontal diseases in patients with diabetes mellitus. …”
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La vie des mots en analyse du travail by Muriel Henry, Maryse Bournel Bosson

“…Work analysis methods in “Clinic of Activity” involve professionals in confrontation with films of their real action. …”
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Metabolomic liquid biopsy dynamics predict early-stage HCC and actionable candidates of human hepatocarcinogenesis by Kornelius Schulze, Tim Daniel Rose, Lorenz Adlung, Manuela Peschka, Francesca Pagani, Joao Gorgulho, Thorben W. Fründt, Ismail Labgaa, Philipp K. Haber, Carolin Zimpel, Darko Castven, Arndt Weinmann, Teresa Garzia-Lezana, Moritz Waldmann, Thomas Renné, Hannah Voß, Manuela Moritz, Dorian Orlikowski, Hartmut Schlüter, Jan Baumbach, Myron Schwartz, Ansgar W. Lohse, Samuel Huber, Bruno Sangro, Rocio I.R. Macias, Laura Izquierdo-Sanchez, Jesus M. Banales, Henning Wege, Jens U. Marquardt, Augusto Villanueva, Josch Konstantin Pauling, Johann von Felden

“…Further RRM2, GMPS, BCAT1, PYCR2, and NEU1 are identified in tumor tissue as actionable candidates for prevention. Our data provide the rationale for clinical trials testing liquid biopsy metabolome-based signatures for early HCC detection and the development of chemoprevention strategies.…”
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Carbon Footprint Assessment in Shrimp Pond Farming of Penaeus vannamei Based on Life Cycle Assessment Methods by Yunfei WANG, Xinmeng WANG, Ying LI, Jinzhen YU, Jie KONG, Jihong ZHANG

“…Since the 1980s, China's aquaculture industry has experienced rapid development and sustained growth in aquaculture production, not only providing large quantities of high-quality protein for humans but also becoming an important supplement to ensure global food security. …”
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Understanding abortion-related complications in health facilities: results from WHO multicountry survey on abortion (MCS-A) across 11 sub-Saharan African countries by Özge Tunçalp, Cassimo Bique, Ahmet Metin Gülmezoglu, Veronique Filippi, Richard Adanu, Bela Ganatra, Bukola Fawole, Philip Govule, Zahida Qureshi, Luis Gadama, Seni Kouanda, Caron Rahn Kim, Sally Griffin, Hedieh Mehrtash, Soe Soe Thwin, Folasade Adenike Bello, Ausbert Thoko Msusa, Nafiou Idi, Sourou Goufodji, Jean-Jose Wolomby-Molondo, Kidza Yvonne Mugerwa, Thierry Madjadoum

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Electronic Pillbox-enabled Self-administered Therapy Versus Standard Directly Observed Therapy for Tuberculosis Medication Adherence and Treatment Outcomes in Ethiopia: a Multicent... by Dr Tsegahun Manyazewal, Dr. Yimtubezinash Woldeamanuel, Mr. Tewodros Getinet, Ms Alison Hoover, Dr Kidist Bobosha, Mr Oumer Fuad, Dr. Belete Getahun, Prof. Abebaw Fekadu, Dr. David Holland, Prof. Vincent Marconi

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Protocol for an evaluation of the initiation of an integrated longitudinal outpatient care model for severe chronic non-communicable diseases (PEN-Plus) at secondary care facilitie... by Archana Shrestha, Biraj Man Karmacharya, Robert Kalyesubula, Isaac Ssinabulya, Zipporah Ali, Alma J Adler, Ana Olga Mocumbi, Neil Gupta, Meghnath Dhimal, Bhagawan Koirala, Gedeon Ngoga, Symaque Dusabeyezu, Gene Kwan, Gene Bukhman, Lilian Mbau, Beatriz Manuel, Giovanni Putoto, Santigie Sesay, Emily B Wroe, Yogeshwar Kalkonde, Sergio Chicumbe, Lauren Brown, Abha Shrestha, Lucia González, Matthew M Coates, Jones K Masiye, Mary Theodory Mayige, Wubaye Walelgne Dagnaw, Chiyembekezo Kachimanga, Ana Mocumbi, Ryan McBain, Apoorva Gomber, Fabio Manenti, Roma Chilengi, Yogesh Jain, Sam Patel, Gladwell Gathecha, Julie Makani, Amy McLaughlin, Celina Trujillo, Laura Drown, Reuben Mutagaywa, Todd Ruderman, Gina Ferrari, Chantelle Boudreaux, Humberto Muquingue, Mary Mayige, Jonathan Chiwanda Banda, Andrea Atzori, Neusa Bay, Wondu Bekele, Victoria M Bhambhani, Remy Bitwayiki Nkwiro, Dawson Calixte, Katia Domingues, Darius Fenelon, Innocent Kamali, Catherine Karekezi, Alexio Mangwiro, Fastone Mathew Goma, Emmanuel Mensah, Nicole Mocumbi Salipa, Alvern Mutengerere, Marta Patiño, Devashri Salvi, Fameti Taero, Emílio Tostão, Sterman Toussaint, Abhijit Gadewar, Sunil Jadhao, Chetanya Malik, Alma Adler, Victoria Bhambhani, Susan Donnellan, Kaita Domingues, Sheila Klassen, Andrew Marx, Maia Olsen, Catherine Player, Ramon Ruiz, Ada Thapa, Leslie Wentworth, Allison Westervelt, Ariana Wolgin, Emily Yale, Michael Abiyu, Lemma Ayele, Zelalem Mengistu, Temesgen Sileshi, Natnael Alemayehu, Natnael A Abebe, Nancy Larco, Gideon Ayodo, Peter Mokaya, Jones Masiye, Evelyn Chibwe, Noel Kasomekera, Nicole M Salipa, Riaze Rafik, Lucy Ramirez, Shiva Adhikary, Krishna Aryal, Phanindra Baral, Biraj Karmachaya, Abhinav Vaidhya, Ann Akiteng, Frank Mugabe, Sarah Asio Eragu, Bernard Bukar, Namasiku Siyumbwa, Wibroad Mutale, Kudakwashe Madzeke, Alaisa Mbiriri, Nyamayaro Wencelas, Porika Nyawai, Abaden Svisva, Laura Ruckstuhl

“…Over 3 years, the countries and state are expected to: (1) establish PEN-Plus clinics in one or two district hospitals, (2) support these clinics to mature into training sites in preparation for national or state-level scale-up, and (3) work with the national or state-level stakeholders to describe, measure and advocate for PEN-Plus to support development of a national operational plan for scale-up.Methods and analysis Guided by Proctor outcomes for implementation research, we are conducting a mixed-method evaluation consisting of 10 components to understand outcomes in clinical implementation, training and policy development. …”
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Analyzing trends and future projections in fodder oats (Avena sativa L.) for quality seed production in India by Subhash Chand, Sanjay Kumar, Sanjay Kumar, Ajoy Kumar Roy, Dunna Vijay, Dunna Vijay, Bishwa Bhaskar Choudhary, Indu, Pradeep Kumar, Rajiv Kumar Agrawal, Vijay Kumar Yadav, Pankaj Kaushal, Devendra Kumar Yadava, Ram Vinod Kumar, Awnindra Kumar Singh, Shahid Ahmed, Devendra Ram Malaviya, Rajesh Kumar Singhal, Birendra Prasad, Rahul Kapoor, Amit Kumar Jha, Ravish Panchta

“…However, analysis reveals a narrow genetic base at the varietal level, with a few old and popular varieties (Kent, OS-6, and OS-7) sharing &gt; 70% of the genome in varietal development. …”
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Cardiovascular and Thromboembolic Events in Children and Adults With Glomerular Disease: Findings From the Cure GlomeruloNephropathy (CureGN) Network by Shikha Wadhwani, Sarah A. Mansfield, Abigail R. Smith, Bruce M. Robinson, Eman Abdelghani, Amira Al-Uzri, Isa F. Ashoor, Sharon M. Bartosh, Aftab S. Chishti, Salim S. Hayek, Michelle A. Hladunewich, Bryce A. Kerlin, Siddharth S. Madapoosi, Laura H. Mariani, Amy K. Mottl, Michelle N. Rheault, Michelle M. O’Shaughnessy, Christopher John Sperati, Tarak Srivastava, David T. Selewski, Chia-shi Wang, Craig S. Wong, Donald J. Weaver, Jr., Myda Khalid

“…Laboratory and other clinical data were evaluated separately in models adjusted for base model covariates. …”
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Physics-based Simulation of the 2013 April 11 Solar Energetic Particle Event by Weihao Liu, Igor V. Sokolov, Lulu Zhao, Tamas I. Gombosi, Nishtha Sachdeva, Xiaohang Chen, Gábor Tóth, David Lario, Ward B. Manchester IV, Kathryn Whitman, Christina M. S. Cohen, Alessandro Bruno, M. Leila Mays, Hazel M. Bain

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