High-grade non-muscle invasive urothelial carcinoma in dogs and humans share specific expression of integrin α5β1 by Roberta Lucianò, Maurizio Colecchia, Maurizio Colecchia, Francesca Sanvito, Irene Locatelli, Chiara Venegoni, Alessia Di Coste, Davide Danilo Zani, Angelica Stranieri, Chiara Giudice, Antonella Rigillo, Matteo Gambini, Francesco Montorsi, Francesco Montorsi, Andrea Salonia, Andrea Salonia, Marco Moschini, Massimo Alfano

“…Given the close similarity between high-grade UC in humans and dogs, basic research in the two species and comparative data analysis could strengthen the prospects for rapid development of an improved clinical strategy for the identification and treatment of the small neoplastic lesions responsible for residual high-grade in both species.…”
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The mediating role of physical activity avoidance in the association between weight stigma and physical activity by Po-Ching Huang, Hung-Ching Wu, Ji-Kang Chen, Xavier C.C. Fung, Nadia Bevan, Daniel Kwasi Ahorsu, Mark D. Griffiths, Jung-Sheng Chen, Kuo-Hsin Lee, Amir H. Pakpour, Chung-Ying Lin

“…Measurement invariance of the TAPAS was tested to ensure that the combining of data from Hong Kong and Taiwan participants was appropriate for further analysis. …”
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Community-based interventions targeting multiple forms of malnutrition among adolescents in low-income and middle-income countries: protocol for a scoping review by David Guwatudde, Till Bärnighausen, Ina Danquah, Elisabetta Ferrero, Yemane Berhane, Ali Sie, Clarisse Dah, Jabulani Ncayiyana, Mosa Moshabela, Shannon McMahon, Jacob Burns, Wafaie W. Fawzi, Michael Laxy, Japhet Killewo, Deda Ogum Alangea, Bruno Sunguya, Sara Pedron, Amani Tinkasimile, Uttara Partap, Adi Lukas Kurniawan, Marijana Ranisavljev, Sachin Shinde, Sergej Ostojic, Ntombizodumo Mkwanazi, Christine Neumann, Shuyan Liu, Mary Mwanyika Sando, Ayoade Oduola, Adom Manu, Jan A.C. Hontelez, Magda Rosenmöller, Irene Brandt, Matthias Kern, Joy Mauti, Hanna Y. Berhane, Mashavu Yussuf, Innocent Yusufu, Laetitia Paumard, Millogo Ourohiré, Erick Agure, Tiwatayo Lasebikan, Marina Taonda, Sylvain Somé, Katian Napon, Moussa Ouédraogo

“…Two reviewers will perform data extraction independently, and, where relevant, risk of bias assessment will be conducted using standard Cochrane risk-of-bias tools. …”
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A high-resolution 20K SNP array for comprehensive genotyping and genetic mapping in Nicotiana tabacum L. by Shizhou Yu, Zhixiao Yang, Jie Zhang, Linggai Cao, Jie Liu, Peng Lu, Jiemeng Tao, Jufen Wan, Qingdong Zeng, Tenghang Xu, Peijian Cao, Jingjing Jin, Xueliang Ren

“…To address this, we developed the Ta-LD-SC, a 20K SNP Affymetrix Axiom array, based on resequencing data from 150 tobacco accessions. …”
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A single-cell transcriptomic atlas of human lens epithelium: identification and functional insights into lens stem/progenitor cells by Yuzhou Gu, Lu Chen, Shuying Chen, Yuhao Wu, Shengjie Hao, Feiyin Sheng, Jiali Yuan, Zhenwei Qin, Di Wu, Yu Han, Zengying Yao, Zhijian Chen, I. Michael Wormstone, Yibo Yu, Junbin Qian, Qiuli Fu, Ke Yao

“…TACs specifically express TOP2A and are localized at the lens equator. CytoTRACE analysis to the LEC and LFC data sets provided a differentiation trajectory. …”
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Multi-Comparison of Different Ocular Imaging Modality-based Deep Learning Models for Visually Significant Cataract Detection by Jocelyn Hui Lin Goh, BEng, Xiaofeng Lei, MSc, Miao-Li Chee, MPH, Yiming Qian, PhD, Marco Yu, PhD, Tyler Hyungtaek Rim, MD, PhD, Simon Nusinovici, PhD, David Ziyou Chen, MBBS, FRCOphth, Kai Hui Koh, BSc, Samantha Min Er Yew, BSc, Yibing Chen, BEng, Victor Teck Chang Koh, MBBS, MMed, Charumathi Sabanayagam, MD, PhD, Tien Yin Wong, MD, PhD, Xinxing Xu, PhD, Rick Siow Mong Goh, PhD, Yong Liu, PhD, Ching-Yu Cheng, MD, PhD, Yih-Chung Tham, PhD

“…Researchers have utilized various imaging modalities, including slit beam, diffuse anterior segment, and retinal imaging, to develop deep learning (DL) algorithms for automated cataract analysis. …”
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Management of Children with Speech Disorders via Transcranial Magnetic Stimulation: Non-Randomized Controlled Study by Julia V. Nesterova, George A. Karkashadze, Leonid M. Yatsik, Leyla S. Namazova-Baranova, Elena A. Vishneva, Elena V. Kaytukova, Kamilla E. Efendieva, Daria A. Bushueva, Tinatin Yu. Gogberashvili, Tatiana A. Konstantinidi, Natalia E. Sergeeva, Safarbegim H. Sadilloeva, Marina A. Kurakina, Julia E. Kazanceva, Inessa A. Povalyaeva, Nadezhda A. Ulkina, Tatiana A. Salimgareeva, Natalia S. Sergienko, Oksana D. Mescheryakova, Viktor V. Altunin, Elizaveta V. Leonova, Elena S. Zibrova

“…Furthermore, we carried out side reactions / adverse events registration according to patients and/or their parents complaints confirmed by physical examination, patient’s behavior observation, data from specially developed questionnaire for assessing child’s behavior and well-being (filled up by parents). …”
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Cancer-associated fibroblast-derived fibulin-5 promotes epithelial–mesenchymal transition in diffuse-type gastric cancer via cAMP response element-binding protein pathway, showing... by Jinju Choi, Yoonjin Kwak, Miree Park, Jeong Yeon Jo, Jun Hyuk Kang, Kook Myeong-Cherl, Hang-Rae Kim, Gwanghun Kim, Seong-Ho Kong, Do-Joong Park, Hye Seung Lee, Hyuk-Joon Lee, Jung Mogg Kim, Sang Gyun Kim, Han-Kwang Yang, Ji Kon Ryu, Soo-Jeong Cho

“…Here, to identify distinct biomarkers for DGC compared with intestinal-type gastric cancer, we constructed a comprehensive large-scale signaling network using RNA-sequencing data from three genomic databases (The Cancer Genome Atlas, GSE62254 and GSE26253), developed a mathematical model and conducted simulation analyses. …”
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Identifying practices of information transfer between the hospital and primary care for older adults: a scoping review protocol by Philippe Desmarais, Claire Godard-Sebillotte, Thomas Tannou, Emily G. McDonald, Dounia Rouabhia, Géraldine Layani, Dimitri Yang, Martina Alkot, Andrea Quaiattini, Sabrina Lessard, Aigul Zaripova, Carolyn Pavoni, Sandrine Couture, Yu Qing Huang, Catherine Richer, Julia Chabot, Felix Pageau, Matthieu Calafiore, Karin Fink, Gulin Yilmaz, Beuscart Jean-Baptiste

“…We will use a search strategy developed with a specialised librarian to search four databases (MEDLINE, Embase, CINAHL and AgeLine) and reference lists of selected studies. …”
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Germline genomic profiling of patients with early-onset colorectal cancer by G. Mauri, M. Puzzono, A. Mannucci, F. Gaudioso, H. Mittal, L. Mosca, V. Burgio, S. Ghezzi, M. Ronzoni, S. Mariano, R. Rosati, L. Monti, U. Cavallari, A. Sartore-Bianchi, S. Siena, G.M. Cavestro

“…Moreover, genes not traditionally associated with EO-CRC development are rarely included in germline testing panels. …”
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Association of habitual glucosamine use with risk of microvascular complications among individuals with type 2 diabetes: a prospective cohort study in UK biobank by Zi-Jian Cheng, Yu-feng Luo, Qing-yun Zhu, Yan-fei Wang, Wen-yan Ren, Fei-yan Deng, Lin Bo, Xi-Yuan Jiang, Shu-feng Lei, Long-Fei Wu

“…We aimed to prospectively evaluate the association of habitual glucosamine use with risk of diabetic microvascular complications based on data from the large-scale nationwide prospective UK Biobank cohort study. …”
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A multimodal MRI-based machine learning framework for classifying cognitive impairment in cerebral small vessel disease by Guihan Lin, Weiyue Chen, Yongkang Geng, Bo Peng, Surui Liu, Minjiang Chen, Chunying Pang, Pengjun Chen, Chenying Lu, Zhihan Yan, Shuiwei Xia, Yakang Dai, Jiansong Ji

“…The AutoGluon platform was utilized for model development, and traditional machine learning algorithms were applied for comparison. …”
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The Mediating Role of Burnout in the Relationship Between Emotional Intelligence and Work Engagement Among Hospital Nurses: A Structural Equation Modeling Approach by Bushra Alshammari, Petelyne Pangket, Awatif Alrasheeday, Nadiah Baghdadi, Sameer A. Alkubati, Dolores Cabansag, Neriza Gugoy, Sahar Mazied Alshammari, Abdulaziz Alanazi, Mohammed Dhaifallah Alanezi, Tahani Alshammari, Randy Mateo Valdez, Salman Alshammari, Laila Alharbi, Aliyu Alhaji Abubakar, Alia Alshammari, Farhan Alshammari

“…<b>Conclusions and Implications for Nursing</b>: Integrating EI training into professional development and implementing measures to reduce burnout may improve WE and retention. …”
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Factors associated with attitudes towards HIV cure research among transgender women and travestis: a cross-sectional survey in São Paulo, Brazil by Vivian Iida Avelino-Silva, Robert J Wozniak, Natalia B Cerqueira, Maria Candida S Dantas, Bianca Mahafe, Daniel A C Barros, Edmilson Alves de Medeiros, Ana Carolina Soares de Oliveira, Thiago Sabino, Albert Roggenbuck, Carrie D Johnston, Jez L Marston, Sebastian C Bidegain, Manya Magnus, Esper G Kallas, Douglas F Nixon, Camila S Donini

“…The biggest motivational factors included gaining additional knowledge about HIV infection (77%) and the potential for a longer, healthier life for all (73%).Conclusions As a primary analysis of HIV cure attitudes among the transgender and travesti population as well as the social context in which they are formed, this study identifies opportunities to strengthen the dialogue and develop more educational collaborations between scientific investigators, community educators and the trans-identifying population to ensure that HIV cure research is inclusive of diverse perspectives.…”
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Genetic interaction between oxidative stress and body mass index in a Spanish population by Francisco Lara-Hernández, Rebeca Melero, María Elena Quiroz-Rodríguez, Celeste Moya-Valera, Mariana de Jesús Gallardo-Espinoza, Luis Álvarez, Ingrid Lizeth Valarezo-Torres, Laisa Briongos-Figuero, Jessica Abadía-Otero, Francisco Javier Mena-Martin, Guillermo Saez, Josep Redon, Juan-Carlos Martín-Escudero, Ana-Bárbara García-García, Guillermo Ayala, Felipe Javier Chaves

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Maximum cold ischemia duration for a kidney allograft: a prediction model for allograft failure at the time of organ allocationResearch in context by Clement Gosset, Susana Barbosa, Alexandre Destere, Sebastien Cuozzo, Laetitia Albano, Emmanuel Morelon, Xavier Charmetant, Moglie Le Quintrec, Jean-Emmanuel Serre, Marc Ladrière, Sophie Girerd, Christophe Masset, Dany Anglicheau, Carmen Lefaucheur, Gillian Divard, Enrico Gruden, Matthieu Durand, Dirk Kuypers, Maarten Coemans, Nicolas Glaichenaus, Oriol Bestard, Anders Åsberg, Magali Giral, Maarten Naesens, Antoine Sicard

“…Prediction models were developed using a classical survival analysis and a competing risk framework. …”
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Klebsiella pneumoniae-derived extracellular vesicles impair endothelial function by inhibiting SIRT1 by Xinxin Li, Jinghua Cui, Zanbo Ding, Ziyan Tian, Yiming Kong, Linghai Li, Yang Liu, Wen Zhao, Xueying Chen, Han Guo, Zhengshuo Cui, Xinwei Li, Jing Yuan, Huina Zhang

“…Abstract Background The potential role of Klebsiella pneumoniae (K.pn) in hypertension development has been emphasized, although the specific mechanisms have not been well understood. …”
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Needs for rehabilitation in China: Estimates based on the Global Burden of Disease Study 1990–2019 by Tian Tian, Lin Zhu, Qingzhen Fu, Shiheng Tan, Yukun Cao, Ding Zhang, Mingxue Wang, Ting Zheng, Lijing Gao, Daria Volontovich, Yongchen Wang, Jinming Zhang, Zhimei Jiang, Hongbin Qiu, Fan Wang, Yashuang Zhao, Rongman Jia

“…We conducted the study to explore the rehabilitation needs in China and project the trend of rehabilitation needs from 2020 to 2034. Methods:. The data of health conditions that might potentially benefit from rehabilitation were obtained from Global Burden of Disease (GBD) study. …”
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Understanding and responding to the cost and health impact of short-term health staffing in remote and rural Aboriginal and Torres Strait Islander community-controlled health servi... by Yuejen Zhao, Steven Guthridge, Mark Ramjan, Michael P Jones, John Wakerman, John Humphreys, Annie Tangey, Terry Dunbar, John Boffa, Rosalie Schultz, Michelle S Fitts, Lisa Bourke, Edward Mulholland, Lorna Murakami-Gold, Clarissa Comerford, Narelle Campbell, Supriya Mathew, Zania Liddle, Deborah Russell

“…A key strategy to achieving health service access equity, particularly evident in remote Australia, has been the development of Aboriginal Community Controlled Health Services (ACCHSs). …”
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The effects of SGLT2i on cardiac metabolism in patients with HFpEF: Fact or fiction? by Francesca Cinti, Renzo Laborante, Luigi Cappannoli, Cassandra Morciano, Shawn Gugliandolo, Alfredo Pontecorvi, Francesco Burzotta, Maria Donniacuo, Donato Cappetta, Giuseppe Patti, Andrea Giaccari, Domenico D’Amario

“…By synthesizing the current evidence, this review will provide an in-depth analysis of the mechanisms through which SGLT2i may influence cardiac metabolism in HFpEF, assessing whether their effects are supported by robust scientific data or remain speculative. …”
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