High‐Frequency Mutations in TP53, AXIN1, CTNNB1, and KRAS, and Polymorphisms in JAK1 Genes Among Mongolian HCC Patients by Nomin Bold, Khurelsukh Buyanbat, Ariya Enkhtuya, Nomin Myagmar, Gerelsuren Batbayar, Zolzaya Sandag, Dolgion Damdinbazar, Nomuun Oyunbat, Tuul Boldbaatar, Ankhbayar Enkhbaatar, Gan‐Erdene Baatarjav, Taivan Nanzaddorj, Tsendsuren Oyunsuren, Gantulga Davaakhuu

“…Hepatitis virus infections were significantly associated with these mutations (p < 0.01), suggesting a link between viral infection and genetic alterations in HCC development. Compared to TCGA data, our cohort displayed a significantly higher mutation frequency (p < 0.001 and p < 0.05), indicating potential regional genetic and environmental influences. …”
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Modified double-row suture bridge technique for anterior colliculus fractures combined with deltoid ligament injury: a retrospective study by Jianlong Ni, Zhihao Chen, Wang Wei, Ruiying Li, Dazhi Wang, Dongjian Wang, Zenan Tian, Zhikun Jia, Qichun Song, Meng Feng, Zhibin Shi

“…For clinical outcome evaluation, objective data are presented through clinical examination findings; radiographic assessments, including X-rays and computed tomography (CT); and follow-up analysis utilizing American Orthopaedic Foot & Ankle Society ankle‒hindfoot (AOFAS) scores, Olerud Molander Ankle Scores (OMAS), and visual analogue scale (VAS) scores. …”
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Hepatic irradiation persistently eliminates liver resident NK cells. by Ryosuke Nakano, Masahiro Ohira, Takuya Yano, Yuki Imaoka, Yuka Tanaka, Hideki Ohdan

“…In summary, our data demonstrated that hepatic irradiation abolished the DX5-TRAIL+ liver-resident NK cell population and dampened antitumor activities in the liver for at least two months. …”
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Differences in clinical significance of atrial tachyarrhythmias in idiopathic ventricular fibrillation vs Brugada syndrome: A multicenter study by Tomofumi Mizuno, MD, Nobuhiro Nishii, MD, PhD, Hiroshi Morita, MD, PhD, Takuro Masuda, MD, Akira Ueoka, MD, PhD, Saori Asada, MD, PhD, Yoshimasa Morimoto, MD, Masakazu Miyamoto, MD, Satoshi Kawada, MD, PhD, Tadashi Wada, MD, PhD, Shigeki Hiramatsu, MD, PhD, Keisuke Okawa, MD, Motoki Kubo, MD, PhD, Koji Nakagawa, MD, PhD, Atsuyuki Watanabe, MD, PhD, Kazufumi Nakamura, MD, PhD, Shinsuke Yuasa, MD, PhD

“…Conversely, there was no significant difference in appropriate ICD therapies between the IVF and BrS groups (14 [27.5%] vs 23 [27.1%]; P = 1.000). Cox regression analysis revealed no predictive factors for the development of ATAs in the IVF group. …”
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Study on the evolution of rock damage and blasting characteristics of deep tunnel splitting and drilling with explosives by Shigui FU, Zegong LIU, jinwei QIU, Shuai YANG, Gangjian AN, Guodong QIAO, Xin ZHANG

“…A comparison of existing experimental data with numerical simulation resulted in the development of a constitutive model (RHT model) to simulate the fracture propagation process of rock under cutting seam blasting loads. …”
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Construction of a stromal cell-related prognostic signature based on a 101-combination machine learning framework for predicting prognosis and immunotherapy response in triple-nega... by Fanrong Li, Congnan Jin, Yacheng Pan, Zheng Zhang, Liying Wang, Jieqiong Deng, Yifeng Zhou, Yifeng Zhou, Binbin Guo, Shenghua Zhang, Shenghua Zhang

“…Cell types preferentially distributed in TNBC were identified using odds ratios (OR). Bulk transcriptome data were analyzed using Weighted correlation network analysis (WGCNA) to identify myCAF-, VSMC-, and Pericyte-related genes (MVPRGs). …”
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Epidemiology and Risk Prediction Model of Multidrug-Resistant Organism Infections After Liver Transplant Recipients: A Single-Center Cohort Study by Chuanlin Chen, Desheng Li, Zhengdon Zhou, Qinghua Guan, Bo Sheng, Yongfang Hu, Zhenyu Zhang

“…The model’s predictive performance and discrimination ability were evaluated using receiver operating characteristic (ROC) curves, calibration curves, and decision curve analysis (DCA). <b>Results:</b> 56 (18.60%) patients developed a MDRO infection, including 37 (17.62%) in the training cohort and 19 (20.88%) in the validation cohort. …”
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Estrategias de afrontamiento como intervención al estrés en futbolistas (Coping strategies as a stress intervention in soccer players) by Daniel Edward Lope Fernández, Omar Benjamín Solís Briceño

“…The selection of the sample was non-probabilistic, by which 22 male soccer players from 14 to 23 years of age were selected for the diagnostic study. For the inferential data analysis, non-parametric Wilcoxon t-test for related samples was employed, involving the comparison of 11 players’ means in stress before and after the intervention in the development of coping strategies. …”
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When the Sacred Meets the Market: The Commodification of Islamic Housing in Lima Puluh Kota, West Sumatra by Muhammad Deni Putra, Akhmad Rofiki, Ana Toni Roby Candra Yudha, Ivan Riyadi, Siti Fadilla

“…Employing a socio-legal qualitative approach, the research draws on in-depth interviews with 10 stakeholders (developers and buyers) and an analysis of contractual documents and promotional materials from the Perumahan Syariah Residence. …”
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FTIR-based molecular fingerprinting for the rapid classification of dengue and chikungunya from human sera using machine learning: an observational studyResearch in context by Souvik Das, Subhanita Roy, Aritri Bir, Arindam Ghosh, Tarun Kanti Bhattacharyya, Pooja Lahiri, Basudev Lahiri

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Capacitação de agentes comunitários de saúde para a detecção da demência na fase leve [Capacitating community health workers to detect dementia at the mild stage ] [Capacitación de... by Emanuela Bezerra Torres Mattos, Mariana de Castro Barbosa, Rosilda Mendes

“…Method: this descriptive study compared the performance of eight CHWs from a Basic Health Unit in Santos, by applying semi-structured questionnaires before and after a CPD workshop held in 2018, after approval by the research ethics committee. The data were processed using thematic analysis. Results: the CHWs’ lack of knowledge about dementia points to the need to invest in continuing professional development as an important tool to be used to detect early cases. …”
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Impact of microbiological molecular methodologies on adaptive sampling using nanopore sequencing in metagenomic studies by Josephine Herbert, Stanley Thompson, Angela H. Beckett, Samuel C. Robson

“…Abstract Introduction Metagenomics, the genomic analysis of all species present within a mixed population, is an important tool used for the exploration of microbiomes in clinical and environmental microbiology. …”
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Wet granulation method in the technology of 6,8-dimethyl-2-piperidinomethyl-2,3-dihydrothiazolo[2,3-F]xanthine tablets, which increases the detoxifying function of the liver by A. I. Petrakov, V. V. Sheikin, S. V. Krivoshchekov, A. M. Guryev, M. V. Belousov

“…Based on the Latin square using the Harrington desirability function with analysis of variance of experimental data, it was found the greatest effect on the flowability of granules is on the granule size (influence to 77.68 %, granule size 0.5–1 mm). …”
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Research and application on megawatt level intelligent fracturing pump system in coal mine by Ran LI, Chuliang WANG, Bo LIU, Yanjun FENG, Pengfei JIANG, Rongming CHEN, Jingbin CHEN, Zhuo CHEN, Dalong WANG, Haicheng LU, Zongkai GUO, Tianze CAO, Yuanzheng YU, Chao WANG

“…The system integrates automatic control and variable frequency technology with the design of underground coal mine fracturing pumps, enabling dynamic collection of performance parameter data at various stages of hydraulic fracturing. It provides real-time analysis of the power matching for electrically driven fracturing pumps and achieves full automation of the fracturing process. …”
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Monocyte-derived APCs are central to the response of PD1 checkpoint blockade and provide a therapeutic target for combination therapy by Louis Boon, Matheus H W Crommentuijn, Sjoerd T T Schetters, Laura J W Kruijssen, Yvette van Kooyk, Ernesto Rodriguez, Jan Van den Bossche, Joke M M Den Haan

“…We additionally analyzed existing single cell RNA sequencing data of the myeloid compartment of patients with melanoma undergoing αPD1 ICB. …”
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Histopathological evaluation of the efficacy of carbon nanoparticle staining in detecting lymph node metastasis in colorectal cancer surgery by Qingzhao Feng, Xin Zhang, Shuyang Yang, Yingqi Feng, Hong Chen, Jiafeng Wang, Zijian Li, Shuang Fu, Qi Sun, Min Feng

“…There is a critical need for the development of more accurate active targeting tracers.…”
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OKEN: A Supervised Evolutionary Optimizable Dimensionality Reduction Framework for Whole Slide Image Classification by Soroush Oskouei, André Pedersen, Marit Valla, Vibeke Grotnes Dale, Sissel Gyrid Freim Wahl, Mats Dehli Haugum, Thomas Langø, Maria Paula Ramnefjell, Lars Andreas Akslen, Gabriel Kiss, Hanne Sorger

“…The encoded data can then be used for classification and segmentation while being computationally more efficient. …”
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A qualitative study on the experience of nurses in the health education for patients with ulcerative colitis based on the Ottawa decision support framework (基于渥太华决策支持框架的护士参与溃疡性结肠炎患... by LIANG Zhuolin (梁琢琳), LI Xumiao (李旭苗), WEI Rongsai (魏荣赛), LIU Jingying (刘璟莹), ZHANG Nan (张楠), MA Hongwen (马宏文)

“…The Colaizzi's 7-step analysis method was used to analyze, summarize and refine the themes of the interview data. …”
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Endogenous reactivation cases identified by whole genome sequencing of Mycobacterium tuberculosis: Exploration of possible causes in Latvian tuberculosis patients by Anda Viksna, Darja Sadovska, Vija Riekstina, Anda Nodieva, Ilva Pole, Renate Ranka, Iveta Ozere

“…Methods: Here, we aimed to provide a retrospective individual analysis of the clinical data of pulmonary TB patients with assumed endogenous infection reactivation based on WGS results to identify the reasons for reactivation. …”
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Optimization and Machine Learning in Modeling Approaches to Hybrid Energy Balance to Improve Ports’ Efficiency by Helena M. Ramos, João S. T. Coelho, Eyup Bekci, Toni X. Adrover, Oscar E. Coronado-Hernández, Modesto Perez-Sanchez, Kemal Koca, Aonghus McNabola, R. Espina-Valdés

“…A neural network time series (NNTS) model trained on average year data achieved high accuracy (R²: 0.9253–0.9695). …”
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