The PA-X host shutoff site 100 V exerts a contrary effect on viral fitness of the highly pathogenic H7N9 influenza A virus in mice and chickens by Xia Chen, Ming Kong, Chunxi Ma, Manyu Zhang, Zenglei Hu, Min Gu, Xiaoquan Wang, Ruyi Gao, Shunlin Hu, Yu Chen, Xiaowen Liu, Daxin Peng, Xiufan Liu, Jiao Hu

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Mechanism-based modular psychotherapy versus cognitive behavioural therapy for adolescents and young adults with childhood trauma experiences: study protocol for a feasibility tria... by Till Bärnighausen, Hanna Zimmermann, Christian Schmahl, Stephanie Bauer, Beate Ditzen, Hans-Christoph Friederich, Markus W Haun, Astrid Berner-Rodoreda, Elisabeth Schramm, Svenja Taubner, Corina Aguilar-Raab, Sabine C Herpertz, Manuel Feisst, Frank Enning, Katja I Seitz, Niklas Schouler, Jan Hundertmark, Maximilian Wilhelm, Svea Franz, Christoph W Korn, Ruben Vonderlin, Eva Vonderlin, Josef Bailer, Elias Bopp, Sophia von Stockert, Laura Tabea Kristalis, Claudia Calvano

“…The mechanism-based modular psychotherapy (MeMoPsy) approach is conceptualised as an innovative framework for psychotherapy development. It comprises independent, flexibly applicable interventions from various theoretical backgrounds and evidence-based programmes within a systematic treatment algorithm, thereby tailoring module selection to the specific needs of traumatised adolescents.Methods and analysis In a randomised controlled feasibility trial (RCT), N=80 outpatients between 15 and 25 years of age diagnosed with various mental disorders will receive 28 individual sessions with MeMoPsy or standard cognitive behavioural therapy. …”
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COVID-19 vaccine evidence monitoring assisted by artificial Intelligence: An emergency system implemented by the Public Health Agency of Canada to capture and describe the trajecto... by Su Hyun Lim, Mona Hersi, Ramya Krishnan, Joshua Montroy, Bonnie Rook, Kelly Farrah, Yung-En Chung, Adrienne Stevens, Joseline Zafack, Eva Wong, Nicole Forbes, April Killikelly, Kelsey Young, Matthew Tunis

“…Given the volume of data and analyses required, the AI-augmented processes made this massive undertaking manageable. …”
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Psycho-oncological burden in patients with brain metastases undergoing neurological surgery by Tommaso Araceli, Tommaso Araceli, Anna Fischl, Anna Fischl, Amer Haj, Amer Haj, Christian Doenitz, Christian Doenitz, Eva-Maria Stoerr, Andrea Hillberg, Andrea Hillberg, Martin Vogelhuber, Martin Vogelhuber, Katharina Rosengarth, Katharina Rosengarth, Markus J. Riemenschneider, Markus J. Riemenschneider, Peter Hau, Peter Hau, Raquel Blazquez, Raquel Blazquez, Tobias Pukrop, Tobias Pukrop, Tobias Pukrop, Elisabeth Bumes, Elisabeth Bumes, Nils Ole Schmidt, Nils Ole Schmidt, Martin Proescholdt, Martin Proescholdt

“…PurposeThe development of brain metastases (BM) can significantly increase the psycho-oncological burden in cancer patients, requiring timely intervention. …”
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Helicobacter pylori infection induces DNA double-strand breaks through the ACVR1/IRF3/POLD1 signaling axis to drive gastric tumorigenesis by Xinbo Xu, Xiao Fei, Huan Wang, Xidong Wu, Yuan Zhan, Xin Li, Yan’an Zhou, Chunxi Shu, Cong He, Yi Hu, Jianping Liu, Nonghua Lv, Nianshuang Li, Yin Zhu

“…We conducted a comprehensive analysis of the clinical relevance of ACVR1 by integrating data from public databases and our local collection of human gastric tissues. …”
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The Effect of Liv.52 DS in Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD): A Pilot, Randomized, Double-Blind, Placebo-Controlled, Clinical Study by Jalihal U, Nanda RA, Katariya K, Ramanathan B, Kumawat R

“…After completion of the study, data from 47 subjects were available for analysis (31 in the Liv.52 DS group and 16 in the placebo group).Results: The mean LSM score, was reduced from 7.3 to 6.0 (Change From Baseline = 17.5%) in the active group with statistically significance (p = 0.007) compared to placebo group with LSM score reduction from 7.5 to 6.9 (CFB = 7.29%). …”
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Overview of antimicrobial resistance mitigation efforts in Benin 2024 by Alain K. Aissi, Tokpanou E.C. Koudjo, Filémon T. Tokponnon, Al Fattah Onifade, Akpeedje A.C. Wadagni, Géraud S.R. Padonou, Hervé A. Gbegnide, Léopold A. Azakpa, Adrien M. Hodonou, Roch C. Johnson, Francis M. Dossou

“…Background: Antimicrobial resistance (AMR) is a significant global public health threat that undermines sustainable development. In Benin, high AMR rates to common antibiotics, including last-resort treatments, exacerbate infection outcomes and healthcare costs. …”
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Sociodemographic factors associated with trajectories of depression among urban refugee youth in Kampala, Uganda: A longitudinal cohort study by Zerihun Admassu, Sikky Shiqi Chen, Carmen H. Logie, Moses Okumu, Frannie MacKenzie, Robert Hakiza, Daniel Kibuuka Musoke, Brenda Katisi, Aidah Nakitende, Peter Kyambadde, Lawrence Mbuagbaw

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Alzheimer’s disease biological PET staging using plasma p217+tau by Azadeh Feizpour, Vincent Doré, Natasha Krishnadas, Pierrick Bourgeat, James D. Doecke, Ziad S. Saad, Gallen Triana-Baltzer, Simon M. Laws, Rosita Shishegar, Kun Huang, Christopher Fowler, Larry Ward, Colin L. Masters, Jurgen Fripp, Hartmuth C. Kolb, Victor L. Villemagne, Christopher C. Rowe

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Effects of saffron-grape intercropping on saffron flower number and rhizosphere microbial community by Yuanyuan Tao, Guifen Zhou, Xingchang Zhang, Mengqing Feng, Liqin Li, Xiaodong Qian

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AI for IMPACTS Framework for Evaluating the Long-Term Real-World Impacts of AI-Powered Clinician Tools: Systematic Review and Narrative Synthesis by Christine Jacob, Noé Brasier, Emanuele Laurenzi, Sabina Heuss, Stavroula-Georgia Mougiakakou, Arzu Cöltekin, Marc K Peter

“…The systematic review followed PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) guidelines and the Cochrane Handbook for Systematic Reviews. Data were analyzed using NVivo through thematic analysis and narrative synthesis to identify key emergent themes in the studies. …”
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Applying affect coding and dynamical systems mathematical modeling to understanding the role of emotional expression on the therapeutic relationship across an entire course of subs... by Gina Cipriano, Paul R. Peluso, Emma Bright, Blanka Hutarkova

“…The sessions were coded using the Specific Affect Coding System (SPAFF) to code emotional expressions and a dynamical systems (DS) mathematical model, with parameters derived from the coded data to create unique models for each session.ResultsStatistical analysis was used to compare SPAFF codes and model parameters between Alan Marlatt and his client. …”
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Determinants of air pollution: empirical evidence from the largest CO2 emitters by elnaz asadi, abolfazl deylami, ali keramatzadeh

“…Our results from the Hausman test did not reject the null hypothesis, suggesting that the random effects estimator was more appropriate for our data than the fixed effects estimator. The results from the FMOLS and DOLS estimations indicated that energy consumption from renewable sources, trade openness, financial development, and urbanization had a negative impact on CO2 emissions, while the energy consumption from non-renewable sources had a positive impact.Conclusion: The results of the research imply that policymakers should focus more on public awareness of renewable energy, mainly in solar and wind power to alleviate environmental pressure and CO2 emission. …”
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Acolhimento na unidade neonatal: percepção da equipe de enfermagem [Embracement at neonatal unit: perception of the nursing team] [Acogimiento en la unidad neonatal: percepción del... by Roberta Costa, Melissa Orlandi Honorio Locks, Patrícia Klock

“…It was methodologically based on the Convergent-Care Research. Data collection was made on the basis of a structured questionnaire and treated with Bardin’s content analysis. …”
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TECHNIQUES OF "COMPETITIVE PAIRS" WHILE TRAINING DENTAL DOCTORS by V. V. Ekhalov, A. V. Samoilenko, I. A. Romanyuta

“…At the same time, three main components of the concept of critical thinking were basis of the systematization of techniques and strategies within this methodology: cognitive (development of mental levels), communicative (development of interactions) and reflexive (the development of professional reflection). …”
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Epidemiology of Vancomycin-Resistant Enterococci in Various Medical Wards by A. V. Liubimova, N. A. Shalyapina, V. V. Kolodzhieva, S. A. Riachovskich, O. V. Dmitrieva, T. V. Brodina, A. A. Shishmakov

“…Vancomycin-resistant enterococci (VRE) have become one of the leading cause of health care-associated infections. Data on occurrence and spread of these pathogens in different types of hospital units are needed to develop effective surveillance and control measures to prevent dissemination of VRE. …”
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Levels of E, A, M, G immunoglobulins in children with newly diagnosed tuberculosis at the beginning of antimycobacterial therapy by O. M. Raznatovska, Yu. V. Mironchuk, O. S. Lytvynenko

“…The results of the study were processed by modern methods of analysis on a personal computer using statistical software package Statistica® for Windows 6.0 (StatSoft Inc., AXXR712 D833214FAN5). …”
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Bone fragility in Type 2 Diabetes Mellitus. Influence of sex and cardiovascular disease in a pilot study using metabolomics by Nicolás Redecilla-Montoya, Cristina García-Fontana, Tomás Clive Barker-Tejeda, Andrea Macías-Camero, Francisco Andújar-Vera, María Fernanda Rey-Stolle, Luis Martínez-Heredia, Iván Iglesias-Baena, Ana Gradillas, Coral Barbas, Beatriz García-Fontana, Manuel Muñoz-Torres, Alma Villaseñor

“…After analysis of these scenarios, our results suggest that acylcarnitines and glycerophospholipids, among other metabolites, are involved in the development of bone fragility in T2DM.…”
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Cloning and Expression of a Truncated Form of the p72 Protein of the African Swine Fever Virus (ASFV) for Application in an Efficient Indirect ELISA System by Julieta Sandra Cuevas-Romero, Perla Lucero Zavala-Ocampo, Sonia Pina-Pedrero, Llilianne Ganges, Adriana Muñoz-Aguilera, José Bryan García-Cambrón, Fernando Rodriguez, Aruna Ambagala, José Luis Cerriteño-Sánchez

“…The inter-assay coefficient of variation (CV 10.4%) and intra-assay CV (2.8%) data show that the assay is precise and reproducible. …”
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IL1RAP is an immunotherapeutic target for normal karyotype triple-mutated acute myeloid leukemia by Arnaud Métois, Marie-Eve Bordeleau, Louis Theret, Azadeh Hajmirza, Ossama Moujaber, Jean-François Spinella, Jalila Chagraoui, Nadine Mayotte, Isabel Boivin, Éric Audemard, Léo Aubert, Véronique Lisi, Banafsheh Khakipoor, Azer Farah, Éric Bonneil, Alma Robert, Julie Lippens, Anna Moraitis, François Béliveau, Albert Feghaly, Geneviève Boucher, Richard Marcotte, Patrick Gendron, Pierre Thibault, Sébastien Lemieux, Guillaume Richard-Carpentier, Vincent-Philippe Lavallée, Josée Hébert, Philippe P. Roux, Guy Sauvageau

“…Results Herein, using multi-omics data from the Leucegene collection, we identify IL1RAP as a promising antigen for this AML subgroup. …”
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