Socio-economic model of the new system of higher environmental education in Russia by Alla V. Guslyakova, Alla V. Guslyakova, Konstantin V. Isaev, Tatyana N. Ledashcheva, Nailya G. Valeeva, Nina I. Guslyakova

“…Simultaneously, almost 94% of young people surveyed believe that university students should be environmentally active and help their university build a more sustainable and healthy academic and research environment. Statistical data in the analyzed graph G has showed the maximum sums of weights on the nodes which reflect the indicators of domestic state policy (20.84); foreign state policy (21.4); demands for environmental specialists in the world (21.01); environmentally caused diseases in Russia and the world (16.00); the knowledge of foreign languages as a tool that expands general educational horizons about sustainable development of the planet (12.50).DiscussionThe study concludes that the Russian Federation is aligning its educational reforms with global trends in sustainable development. …”
Get full text

A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testingResearch in context by Yidong Chen, Jin Huang, Fuchou Tang, Lu Wen, Jie Qiao

“…To investigate this, we retrieved single-cell-resolution DNA methylation data from oocytes (n = 33), inner cell masses (ICMs, n = 74), TEs (n = 71) and sperm cells (n = 21), bulk DNA methylation data from cumulus cells, and DNA methylation data from SECM samples (n = 194) from our previously published database, and conducted a comparative analysis of DNA methylation patterns among them. …”
Get full text

A nomogram integrating the clinical and CT imaging characteristics for assessing spread through air spaces in clinical stage IA lung adenocarcinoma by Yantao Yang, Li Li, Huilian Hu, Chen Zhou, Qiubo Huang, Jie Zhao, Yaowu Duan, Wangcai Li, Jia Luo, Jiezhi Jiang, Zhenghong Yang, Guangqiang Zhao, Yunchao Huang, Lianhua Ye

“…Additionally, the calibration curve and decision analysis curve demonstrated high calibration and clinical applicability of the model in both cohorts.ConclusionBy integrating clinical and CT imaging characteristics, a nomogram model was developed to predict the occurrence of STAS, demonstrating robust predictive performance and providing valuable support for decision-making in patients with stage IA lung adenocarcinoma.…”
Get full text

The TAAR1 Agonist PCC0105004 Regulates Amygdala Synaptic Plasticity to Alleviate Anxiety‐Like Behaviors in Rats by Yingtian Zhang, Wei Zhang, Linyao Yu, Yaoqin Shi, Min Xu, Hui Wang, Chunmei Li, Jingwei Tian

“…These results suggest that PCC0105004 is a promising anxiolytic candidate for pharmacotherapy of anxiety and warrants further examination and development.…”
Get full text

Early warning and stratification of the elderly cardiopulmonary dysfunction-related diseases: multicentre prospective study protocol by Ping Wang, Min Zhou, Li Fan, Yi Xia, Ziwei Zhang, Zhiping Guo, Zaiyi Liu, Yang Hou, Xiuxiu Zhou, Qianxi Jin, Yu Guan, Chuanchang Li, Yongping Bai, Wei-Hua Liao, Hongyu Lin, Shiyuan Liu

“…By leveraging artificial intelligence technology, multimodal data will be integrated to establish reference ranges for cardiopulmonary function in the elderly population, as well as to develop early-warning models and severity grading standard models.Ethics and dissemination The study has been approved by the local ethics committee of Shanghai Changzheng Hospital (approval number: 2022SL069A). …”
Get full text

Magnetic Field Meter Based on CMR-B-Scalar Sensor for Measurement of Microsecond Duration Magnetic Field Pulses by Pavel Piatrou, Voitech Stankevic, Nerija Zurauskiene, Skirmantas Kersulis, Mindaugas Viliunas, Algirdas Baskys, Martynas Sapurov, Vytautas Bleizgys, Darius Antonovic, Valentina Plausinaitiene, Martynas Skapas, Vilius Vertelis, Borisas Levitas

“…A bipolar pulsed voltage supplying the sensor minimized the parasitic effects of the electromotive force induced in the probe circuit. The data were transmitted via a fiber optic cable to a PC equipped with a special software for processing and recording. …”
Get full text

A global atlas and drivers of antimicrobial resistance in Salmonella during 1900-2023 by Yanan Wang, Xuebin Xu, Shulei Jia, Mengqi Qu, Yuhang Pei, Shaofu Qiu, Jianmin Zhang, Yue Liu, Sufang Ma, Na Lyu, Yongfei Hu, Jianli Li, Erqin Zhang, Bo Wan, Baoli Zhu, George F. Gao

“…Here, we performed an analysis of publicly available data of 208,233 Salmonella genomes in 148 countries/regions between 1900 and 2023 and explored driving indicators of AMR. …”
Get full text

Population-specific reference panel improves imputation quality for genome-wide association studies conducted on the Japanese population by Jack Flanagan, Xiaoxi Liu, David Ortega-Reyes, Kohei Tomizuka, Nana Matoba, Masato Akiyama, Masaru Koido, Kazuyoshi Ishigaki, Kyota Ashikawa, Sadaaki Takata, MingYang Shi, Tomomi Aoi, Yukihide Momozawa, Kaoru Ito, Yoshinori Murakami, Koichi Matsuda, The Biobank Japan Project, Yoichiro Kamatani, Andrew P. Morris, Momoko Horikoshi, Chikashi Terao

“…Abstract To improve imputation quality for genome-wide association studies (GWAS) conducted on the Japanese population, we developed and evaluated four Japanese population-specific reference panels. …”
Get full text

Evaluating axillary lymph node metastasis risks in breast cancer patients via Semi-ALNP: a multicenter studyResearch in context by Limeng Qu, Jinfeng Zhu, Xilong Mei, Zixi Yi, Na Luo, Songlin Yuan, Xuan Liu, Mingwen Liu, Haiqing Xie, Xiongqiang Hu, Liangrui Pan, Qingchun Liang, Yanhui Li, Qiongyan Zou, Qin Zhou, Danhua Zhang, Meirong Zhou, Lei Pei, Ke Qian, Qian Long, Qitong Chen, Xi Chen, Jennifer K. Plichta, Qingyao Shang, Meishuo Ouyang, Jiachi Xu, Wenjun Yi

“…Funding sources were not involved in the study design, data collection, analysis and interpretation, writing of the report, or decision to submit the article for publication.…”
Get full text

ChatGPT for the Standardized Operative Notes in Plastic Surgery by Fizzah Arif

“…Please elaborate top 5 crucial roles. ChatGPT: 1. Data Collection and Analysis: ChatGPT can be trained to understand and analyze large amounts of operative notes data to identify patterns, discrepancies, and areas for improvement in standardization. 2. …”
Get full text

Piezo1-related physiological and pathological processes in glioblastoma by Weijia Fu, Weijia Fu, Weijia Fu, Xue Hou, Xue Hou, Xue Hou, Lijuan Ding, Lijuan Ding, Lijuan Ding, Jiaying Wei, Jiaying Wei, Jiaying Wei, Wei Hou, Wei Hou, Wei Hou

“…Studies have shown that Piezo1 is largely unexpressed in normal brain tissues but is expressed at high levels in glioblastoma and can significantly contribute to glioblastoma development and progression, but its role in the pathogenesis of glioblastoma remains unclear.MethodsWe reviewed the relevant literature and data in six major databases including PubMed, EMBASE, CINAHL, Scopus, Web of Science and TCGA. …”
Get full text

Spatial structural characteristics of the Deda ancient landslide in the eastern Tibetan Plateau: Insights from Audio-frequency Magnetotellurics and the Microtremor Survey Method by Zhen-dong Qiu, Chang-bao Guo, Yi-ying Zhang, Zhi-hua Yang, Rui-an Wu, Yi-qiu Yan, Wen-kai Chen, Feng Jin

“…A novel MSM-based method for sliding zone identification is proposed, achieving less than 5% discrepancy in depth determination when compared with drilling data. These results provide a valuable reference for the spatial structural analysis of large-deep-seated landslides in geologically complex regions like the eastern Tibetan Plateau.…”
Get full text

Overcome the Fear of Exercise in Patients With Bone Metastases: A Qualitative Study on Patients' Perception by Anita Borsati, Daniela Tregnago, Matteo Caleffi, Christian Ciurnelli, Linda Toniolo, Ilaria Trestini, Lorenzo Belluomini, Marco Sposito, Jessica Insolda, Federico Schena, Michele Milella, Sara Pilotto, Alice Avancini

“…Data were analyzed using inductive thematic analysis. …”
Get full text

ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1 by Živa Frangež, Deborah Gérard, Zhaoyue He, Marios Gavriil, Yuniel Fernández-Marrero, Yuniel Fernández-Marrero, S. Morteza Seyed Jafari, Robert E. Hunger, Philippe Lucarelli, Shida Yousefi, Thomas Sauter, Lasse Sinkkonen, Hans-Uwe Simon, Hans-Uwe Simon, Hans-Uwe Simon, Hans-Uwe Simon

“…This reduction correlated with changes in the expression of autophagic activity markers, suggesting decreased basal levels of autophagy in primary and metastatic melanomas. Furthermore, the analysis of survival data of melanoma patients revealed an association between reduced ATG5 and ATG7 levels with an unfavourable clinical outcome. …”
Get full text

qRT-PCR Reference Gene Selection for the Discoloration of Tender Leaves in Hawk Tea (<i>Litsea coreana</i>) by Qianli Dai, Min Lu, Ximeng Yang, Chenggong Lei, Feiyi Huang, Xueping Hu, Xin Huang, Xiaolong Nie, Daojing Chen, Sicheng Huang, Hengxing Zhu

“…To identify stable reference genes for qRT-PCR analysis across different developmental stages and color variations of tender leaves in <i>Litsea coreana</i>, seven candidate reference genes were selected based on existing transcriptome data. qRT-PCR was performed on tender leaves of <i>L. coreana</i> at various stages and under different color conditions. …”
Get full text

The estimated incidence of uterine corpus cancers among permanent residents in mainland China using Bayesian spatial modeling by Shuxiu Hao, Liyuan Guo, Sihong Guo, Chen Feng, Huixin Sun, Linlin Du, Guijin Li, Cheng Wang, Yu Zhang, Cunqi Lv, Qingyu Zeng, Jiacheng Li, Xinshu Wang, Tong Wang, Liping Tang, Qi Li

“…The estimated differences in uterine corpus cancer incidence between PR and HRR provide crucial data support for optimizing prevention strategies and enabling precise allocation of regional healthcare resources.…”
Get full text

Guillain-Barre Syndrome in A Patient with Infectious Endocarditis: Clinical Observation and Literature Review by E. V. Reznik, P. A. Mogutova, M. Kh. Shurdumova, E. V. Astashkevich, A. L. Lukyanov, L. M. Mikhaleva, K. Yu. Midiber, A. P. Smirnov, G. N. Golukhov

“…Brain computed tomography revealed no data for acute focal pathology but showed left-sided sinusitis and ethmoiditis. …”
Get full text

Tyrosine Kinase Inhibitor Resistance in Patients with Chronic Myeloid Leukemia: A 10-Year Study of BCR-ABL Gene Mutation Profile in Russia (2006–2016) by VV Tikhonova, MA Isakov, VA Misyurin, YuP Finashutina, LA Kesaeva, NA Lyzhko, IN Soldatova, NN Kasatkina, EN Misyurina, AV Misyurin

“…Mutation-associated resistance rates varied by region of the Russian Federation. Conclusion. The analysis of trends of mutation incidence in patients with CML can be of extreme significance in long-term prognosis of resistance development and in improvement of treatment planning.…”
Get full text

Conceptual Design Study of a Coffee Stem Gasification Scheme in the Context of a Biorefinery by Camilo Andrés Guerrero-Martin, Leyder Alejandro Prieto-Moreno, Jaime Eduardo Arturo-Calvache, Stefanny Camacho-Galindo, Laura Estefanía Guerrero-Martin, William Alberto Guerrero, Oswaldo Hideo Ando Junior, John Carlos Arevalo, Elizabete Fernandes Lucas

“…A conceptual design of coffee stem biomass gasification was developed using the Aspen Plus process simulator, which was analyzed based on energy criteria such as the lower heating value of the produced synthesis gas and cold gas efficiency. …”
Get full text

Interaction effect of comorbid depression and proactive positivity coping strategy on the 1-year survival of patients with advanced cancer: a nationwide multicentre study in South... by Ju Youn Jung, Je-Yeon Yun, Jung Hun Kang, Su-Jin Koh, Yu Jung Kim, Seyoung Seo, Jung Hoon Kim, JaeKyung Cheon, Eun Joo Kang, Eun-Kee Song, Eun Mi Nam, Ho-Suk Oh, Hye Jin Choi, Jung Hye Kwon, Woo-Kyun Bae, Jung Eun Lee, Kyung Hae Jung, EunKyo Kang, Young Ho Yun

“…Methods This was a secondary analysis of data from a multicentre randomized clinical trial of patients with advanced cancer (ClinicalTrials.gov Identifier: NCT03181854). …”
Get full text