Tushirikiane-4-Uthabiti (Supporting Each Other For Resilience): study protocol of a mental health, HIV self-testing and livelihoods randomised controlled trial for advancing HIV pr... by Daniel Kibuuka Musoke, Aidah Nakitende, Carmen H Logie, Moses Okumu, Peter Kyambadde, Robert Hakiza, Lauren Tailor, Frannie MacKenzie, Zerihun Admassu, Brenda Katisi

Get full text

Cancer pain and quality of life structural equation model based on the biopsychosocial model by Xiaoyu Hu, Jingjing Lü, Chang Qin, Xiaoxuan Liu, Jianbiao Zhu, Yongchun Cui

“…Results Two SEMs were developed to elucidate relationships between cancer pain and quality of life. …”
Get full text

Application of machine learning assisted multi-variate UV spectrophotometric models augmented by kennard stone clustering algorithm for quantifying recently approved nasal spray co... by Ahmed Emad F. Abbas, Mohammed Gamal, Ibrahim A. Naguib, Michael K. Halim, Basmat Amal M. Said, Mohammed M. Ghoneim, Mohmeed M. A. Mansour, Yomna A. Salem

“…A comprehensive sustainability assessment employed six state-of-the-art tools, including the national environmental method index, complementary green analytical procedure index, analytical greenness metric, blue applicability grade index, carbon footprint analysis, and the red-green-blue 12 metrics. Favorable results across all metrics affirmed the method’s eco-friendliness, real-world applicability, and cost-effectiveness, supporting sustainable development goals in pharmaceutical quality control processes.…”
Get full text

Numerical Solution to the Problem of Thermal Conductivity in a Porous Plate with a Topology of Triply Periodic Minimal Surfaces by K. V. Gubareva, A. V. Eremin

“…The current gap in scientific knowledge is the lack of systematization and generalization of existing data, which complicates the development of universal approaches to calculating thermal conductivity in such materials. …”
Get full text

Related factors of anemia in maintenance hemodialysis patients by HOU Xin-yan, LIU Di, LIU Ye-xin, TAN Xia, LI Hui-qiong, LIU Hai-yang, YUAN Fang, HE Li-yu, LIU Yu, WANG Chang, ZHOU Le-tian, ZHANG Lei, LI Zheng, CHEN Guo-chun, CHEN Xiao-jun, LIU Hong

“…Objective To investigate the target achievements of hemoglobin in maintenance hemodialysis（MHD） patients and related influencing factors in our center.Methods The study focused on the patients with end stage renal disease who had done hemodialysis more than 3 months in our hospital.We collected the information of age,sex,primary disease,weight,hemodialysis duration,hemodialysis frequency,appendix medicines and the examination records of ferritin,albumin,blood urine nitrogen,serum creatinine from January 1,2014 to January 1,2015.Then we classified the patients into different groups according to hemoglobin（Hb） level,with the chi-square test to compare the Hb levels,usage condition of erythropoietin and ferralia among these groups.Results（1） 257 MHD patients were involved in this research with the level of Hb ≥110 g/L as the target value.123 patients reached the target level,accounting for 46.7%,and 134 patients did not reach the target level,accounting for 53.3%.The target rate of Hb level was similar with domestic,but lower than foreign developed countries.These patients were assigned to different groups on the basis of their primary disease,and the top 5 were as follows:hypertensive kidney diseases（92 cases,35.80%）,chronic nephropathy（82 cases,31.91%）,diabetic kidney diseases（40,15.56%）,polycystic kidney（7,2.72%）,gout（6,2.33%）.The prevalence of anemia among these primary diseases showed significant difference（P = 0.042<0.05）.（2） The patients were classified by Hb levels.The dose of EPO[（60.54 + 50.4） IU·kg^-1·W^-1vs.（136.51+36.32） IU·kg^-1·W^-1,P<0.001]and intravenous iron[（139.01 ± 52.08） mg vs.（150 ± 78.59） mg,P<0.001) in Hb<110 g/L group were lower than in Hb ≥110 group.However,there were no statistically significant differences in age,weight,hemodialysis duration,ferritin,albumin,serum uric acid,serum creatinine between Hb<110 g/L group and Hb ≥110 group.The patients were classified by the dose of ferralia.There was no obvious difference in Hb levels between intravenous and oral groups.（3） The correlation analysis showed that the Hb level was associated with the doses of EPO（r= 0.849,P<0.01） and ferralia（r= 0.196,P<0.01）.Conclusions（1） These data showed that the standard rate of anemia treatment was 46.7%in our hemodialysis center,similar to domestic,but lower than foreign developed countries.（2） In the MHD patients given EPO,the Hb level and Hb standard rate were higher.（3） Among MHD patients using ferralia,the standard rate of Hb was higher than in those unused.And there was no obvious difference between intravenous and oral ferralia（4） The level of Hb was positively related with EPO doses and the use of ferralia.…”
Get full text

Balancing Care and Sacrifice: Lived Experiences and Support Needs of Primary Caregivers in Pediatric Chronic Pain Across Canada and Australia by Nicole Pope, Nicole Drumm, Kathryn A. Birnie, Melanie Noel, Carolyn Berryman, Nicki Ferencz, Tieghan Killackey, Megan Macneil, Darrel Zientek, Victoria Surry, Jennifer N. Stinson

“…Semi-structured interviews were co-facilitated by caregiver partners. Thematic analysis was applied to interview data. Results: Two overarching themes were identified: (1) bearing the weight and sacrifice of caregiving and (2) deep interrelatedness and blurred boundaries. …”
Get full text

Cartography and Epidemiological Study of Leishmaniasis Disease in Sefrou Province (2007–2010), Central North of Morocco by Fatima Zahra Talbi, Fatiha El Khayyat, Hajar El Omari, Saâd Maniar, Mouhcine Fadil, Amal Taroq, Abdellatif Janati Idrissi, Abdelhakim El Ouali Lalami

“…The data were analyzed by SPSS software (version 20). …”
Get full text

Co-creation of a qualitative fertility research study to understand waiting time experiences through patient engagement by Madison Healey, Julia Craig, Sarah Thomas, Jillian Tizzard, Kelsey Puddister, Erin L McGowan, Laurie K Twells, Katie P Wadden

“…Data from research team discussion groups were documented using a meeting minutes template. …”
Get full text

A Novel Preclinical Murine Model of Systemic Lupus Erythematosus–Like Cardiovascular Disease by Marice K. McCrorey, Kennedy P. Hawkins, Marharyta Semenikhina, Matthew Bernstein, Ryan Lacey, C. Alex Colvert, Jim C. Oates, Betty P. Tsao, Kristine Y. DeLeon‐Pennell, Oleg Palygin, Melissa A. Cunningham, Justin P. Van Beusecum

“…Clinical studies have demonstrated that patients with SLE are more likely to develop CVD, including cardiac and vascular dysfunction. …”
Get full text

Tririum in urine in residents of Ozyorsk, the Chelyabinsk region in 2016 by L. V. Finashov, V. V. Vostrotin, A. Yu. Yanov

“…Measurement of tritium volume activity in the urine was performed using up-to-date ultra low level beta spectrometer Quantulus-1220. A questionary was developed that allowed collection of individual data on the water intake regime, on the occupational activity and the living conditions of people under study. …”
Get full text

Decades of discovery: unveiling emerging trends, pivotal research areas, and landmark publications in national tobacco research in India by Alok Singh, Akanksha Kashyap, Saurabh Varshney, Sudip Bhattacharya

“…Data were retrieved from the SCOPUS database, limited to peer-reviewed journal articles and reviews published in English. …”
Get full text

Health-preserving physical culture and wellness competences as an important condition for ensuring and spreading a high level of public health (methodological aspects) by A. M. Hurieieva, V. V. Prykhodko, O. V. Sheviakov, S. A. Chernihivska, V. M. Vilianskyi, O. O. Cherepok

“…The used methods of theoretical research were: study and generalization of data from domestic and foreign official and literary sources, as well as abstraction, analysis and synthesis, induction and deduction. …”
Get full text

Dynamic Nomogram for Predicting the Fall Risk of Stroke Patients: An Observational Study by Wu Y, Jiang X, Wang D, Xu L, Sun H, Xie B, Tan S, Chai Y, Wang T

“…Forward stepwise regression was used to analyze the data, and a dynamic nomogram model was developed.Results: During follow-up, three patients died, and 16 failed the follow-up, with a failure rate of 3.89%. …”
Get full text

Phylogeny and systematics of Arabian lacertids from the Mesalina guttulata species complex (Squamata, Lacertidae), with the description of a new species by Jiří Šmíd, Doubravka Velenská, Lukáš Pola, Karin Tamar, Salem Busais, Mohammed Shobrak, Mohammed Almutairi, Al Faqih Ali Salim, Saad Dasman Alsubaie, Raed Hamoud M. AlGethami, Abdulaziz Raqi AlGethami, Abdulkarim Saleh K Alanazi, Ahmed Mohajja Alshammari, Damien M. Egan, Ricardo O. Ramalho, David Olson, Josh Smithson, Laurent Chirio, Marius Burger, Ryan van Huyssteen, Melissa A. Petford, Salvador Carranza

Get full text

Theoretical Insights into the Chemical Bonding, Electronic Structure, and Spectroscopic Properties of the Lanarkite Pb₂SO₅ Structure by Guilherme S. L. Fabris, Mateus M. Ferrer, Claudio R. R. Almeida, Carlos A. Paskocimas, Julio R. Sambrano, Felipe A. La Porta

Get full text

Saline nasal irrigation and gargling in COVID-19: Part II. Outcomes in Omicron and risk–benefit for self-care by S. Huijghebaert, C. Fabbris, C. Fabbris, A. L. Baxter, S. Parviz, U. S. Chatterjee, D. Rabago

“…Early initiation of daily SNI/gargling before the onset of smell/taste dysfunction prevented their development. Daily SNI hygiene was also associated with less frequent development of fever and a shorter duration of fever than observed among (non-irrigating) controls. …”
Get full text

The transcription factor BBX regulates phosphate homeostasis through the modulation of FGF23 by Su Jeong Lee, Ju Ang Kim, Hye Jung Ihn, Je-Yong Choi, Tae-Yub Kwon, Hong-In Shin, Eui-Sic Cho, Yong Chul Bae, Rulang Jiang, Jung-Eun Kim, Eui Kyun Park

“…Furthermore, the ubiquitination of BBX followed by proteasomal degradation was required for the increase in Fgf23 expression induced by 1,25(OH)2D3. Collectively, our data demonstrate that BBX negatively regulates Fgf23 expression, and consequently, the ubiquitin-dependent proteasomal degradation of BBX is required for FGF23 expression, thereby regulating phosphate homeostasis and bone development in mice.…”
Get full text

DERMOID AND EPIDERMOID CYSTS OF THE MAXILLOFACIAL AREA AND THE NECK AMONG CHILDREN by P.I. Tkachenko, I.I. Starchenko, S.O. Bilokon, Y.V. Popelo, N.P. Bilokon, V.V. Yarkovy

“…The aim of the study is to study in a comparative aspect their own experience on the clinical and morphological features and principles of treatment of dermoid and epidermoid cysts of the maxillofacial area and neck in children with the results of scientific studies, covered in literature. A thorough analysis of fundamental scientific works and publications in periodicals devoted to the scientific development of various directions in relation to these issues is carried out. …”
Get full text

RETRACTED ARTICLE: Bone mesenchymal stem cell-derived exosomal microRNA-7-5p inhibits progression of acute myeloid leukemia by targeting OSBPL11 by Duanfeng Jiang, Xin Wu, Xiaoying Sun, Wei Tan, Xin Dai, Youbang Xie, Ashuai Du, Qiangqiang Zhao

“…The data will inform the development of AML therapies based on BMSC-derived exosomes. …”
Get full text

Parallels of structural-functional parameters the myocardium, C-type natriuretic peptide and endothelin-1 plasma concentrations in women with uncomplicated essential hypertension by V. V. Petrovska, B. M. Zhebel

“…The development of endothelial dysfunction (DE)plays an important role in the pathogenesis of essential hypertension (EH). …”
Get full text