Single cell RNA sequencing after moderate traumatic brain injury: effects of therapeutic hypothermia by Nadine A. Kerr, James Choi, Simone Y. Mohite, Praveen Kumar Singh, Helen M. Bramlett, Jae K. Lee, W. Dalton Dietrich

“…Unbiased clustering revealed cellular heterogeneity among glial and immune cells at this subacute posttraumatic time point. The analysis also revealed vascular and immune subtypes associated with neovascularization and debris clearance, respectively. …”
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OSBPL3 modulates the immunosuppressive microenvironment and predicts therapeutic outcomes in pancreatic cancer by Qihui Sun, Xiaoqi Zhu, Qi Zou, Yang Chen, Tingting Wen, Tingting Jiang, Xiaojia Li, Fang Wei, Keping Xie, Jia Liu

“…We integrated multi-dataset analyses, single-cell transcriptomic data, and functional experiments to explore the role of OSBPL3 in pancreatic cancer. …”
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Acceptance and readiness for tele-dentistry among dental professionals amidst conflict in Sudan by Sara Omer Alabass, Yasir Ahmed Mohammed Elhadi, Mohamed Mustafa Saeed Alhussain, Reem Esam Siddig, Atika Osman Abdalla Elfaki, Elhassan Elaish Yousif Elgayli, Mohamed Abubaker Hasabelrasoul Abdelrahman, Almodathir Balla Alamin, Rayan Mustafa Saeed Elhusien, Ashraf Ismail Mohammed Kara, Nada Tawfig Hashim

“…These findings provide important insights to guide the development of tele-dentistry policies and capacity-building initiatives in Sudan.…”
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From Asymmetry to Satisfaction: The Dynamic Role of Perceived Value and Trust to Boost Customer Satisfaction in the Tourism Industry by Ibrahim A. Elshaer, Alaa M. S. Azazz, Sameh Fayyad, Abdulaziz Aljoghaiman, Eslam Ahmed Fathy, Amr Mohamed Fouad

“…SmartPLS 3 software implemented the data analysis process using partial least squares structural equation modeling (PLS-SEM). …”
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Housing type and risk of depression – the mediating effects of perceived indoor annoyances and loneliness: a Danish cohort study, 2000–2018 by Anne Marie Kirkegaard, Stine Kloster, Michael Davidsen, Anne Illemann Christensen, Klaus Martiny, Carlo Volf, Steffen Loft, Niss Skov Nielsen, Lars Gunnarsen, Annette Kjær Ersbøll

“…Therefore, the aim was to investigate the association between housing type and the development of incident depression. Furthermore, quantifying the mediated effects through perceived indoor annoyances and perceived loneliness for the association between housing type and depression. …”
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Targeted Inhibition of cGAS/STING signaling induced by aberrant R-Loops in the nucleus pulposus to alleviate cellular senescence and intervertebral disc degeneration by Dan Wu, Chen Yan, Linhui Han, Fudong Li, Ximing Xu, Jingchuan Sun, Yong Cao, Kaiqiang Sun, Jiangang Shi, Yuan Wang

“…Through integrative analysis of single-cell RNA-seq data from intervertebral discs (IVDs), we have firstly uncovered that the aberrant accumulation of R-Loops—a type of triple-stranded nucleic acid structure—can result in the cytoplasmic accumulation of double-stranded DNA (dsDNA) and activate cGAS/STING signaling and induce cellular senescence in nucleus pulposus cells (NPCs) during IVDD. …”
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Advanced imaging-enabled understanding of cell wall remodeling mechanisms mediating plant drought stress tolerance by Nannan Zhao, Zhiguo Zhou, Shunli Cui, Xinye Zhang, Shu Zhu, Ying Wang, Tinashe Zenda, Li Wenjing

“…Integrating latest cell wall imaging techniques to innovative single-cell omics, genome editing, and advanced data analysis approaches could facilitate appropriate cell wall modifications necessary for drought tolerance engineering in crop plants.…”
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Surgical stabilization of rib fractures in conjunction with veno-venous ECMO for traumatic chest wall injury: a multi-institutional case series from the Chest Wall Injury Society (... by Joseph D Forrester, Gaurav Sachdev, Jamie Tung, John A Farag, Daniel Stoltz, Stephanie Jensen, Sean Dieffenbaugher, Aneyesis D Gonzalez-Suarez, Samuel Ross, Amer Afaneh

“…Descriptive analysis was planned given the low number of anticipated patients. …”
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Slow Pyrolysis as a Method of Treating Household Biowaste for Biochar Production by Agnieszka Bezuszko, Marcin Landrat, Krzysztof Pikoń, Ana F. Ferreira, Abel Rodrigues, Gabor Olejarz, Max Lewandowski

“…Consequently, there is a need to develop new and better methods of treating it. A significant part of municipal waste is biowaste, which can be treated as a source of valuable resources such as nutrients, organic matter, and energy. …”
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Enhancing community participation for stroke survivors with cognitive impairment: study protocol for a randomised controlled trial in Taiwan by Tsan-Hon Liou, Lu Lu, Feng-Hang Chang, Valeria Chiu, Pengsheng Ni, Yen-Nung Lin, Jiunn-Horng Kang, Der-Sheng Han, Elizabeth R Skidmore

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Immunological Responses to Tetanus and Influenza Vaccination in Donkeys by Maciej Perzyna, Jowita Grzędzicka, Dominika Milczek‐Haduch, Izabela Dąbrowska, Michał Trela, Bartosz Pawliński, Olga Witkowska‐Piłaszewicz

“…ABSTRACT Background Donkeys are routinely vaccinated with protocols developed for horses, yet species‐specific data on their immune responses are limited. …”
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Predictors of transition from independence to limitations in activities of daily living (ADL) among independent community-dwelling older adults: longitudinal evidence from the Mala... by Shakirah Md. Sharif, Suhana Jawahir, Weng Hong Fun, Ee Hong Tan, Alif Haikal Md. Razman, Halimah Awang, Sondi Sararaks, Norma Mansor

“…Methods A prospective cohort study using data from 2275 adults aged 60 and above from the Malaysia Ageing and Retirement Survey, was conducted. …”
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Fmoc-FF Nanogel-Mediated Delivery of Doxorubicin and Curcumin in Thyroid Cancer Cells by Enrico Gallo, Giovanni Smaldone, Luca Cimmino, Mariantonia Braile, Francesca Maria Orlandella, Neila Luciano, Antonella Accardo, Giuliana Salvatore

“…<b>Conclusions:</b> Overall, the data suggest that Fmoc-FF NGs represent a promising strategy for delivering agents with diverse physicochemical properties in TC, enhancing their efficacy and safety and warranting further investigation.…”
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Detection of structural variants linked to mutton flavor and odor in two closely related black goat breeds by Lingle Chang, Xi Niu, Shihui Huang, Derong Song, Xueqin Ran, Jiafu Wang

“…Abstract Background Mutton quality is closely related to genetic variants and gene expression alterations during growth and development, resulting in differences in nutritional values, flavor, and odor. …”
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Genomic, socio-environmental, and sequencing capability patterns in the surveillance of SARS-CoV-2 in Latin America and the Caribbean up to 2023 by Macarena Concha-Toloza, Luis Collado González, Alfredo Herrera Estrella, Darío Fernández Do Porto, Rebeca Campos Sánchez, Jose Arturo Molina-Mora

“…This study aimed to provide information to the regional SARS-CoV-2 surveillance programs by determining genomic, socio-environmental, and sequencing capacity patterns associated with the circulation of the virus in Latin America up to 2023. Data from 24 countries in LAC were analyzed using public databases up to December 2023. …”
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Early urea-to-creatinine ratio to predict rapid muscle loss in critically ill patients with sepsis: a single-center retrospective observational study by Jie Jiang, Hui Chen, Shan-shan Meng, Chun Pan, Jian-Feng Xie, Feng-Mei Guo

“…This study aimed to investigate whether changes in UCR (ΔUCR) can predict the development of rapid muscle loss in patients with sepsis. …”
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New Diabetes Questionnaire to add patients’ perspectives to diabetes care for adults with type 1 and type 2 diabetes: nationwide cross-sectional study of construct validity assessi... by Unn-Britt Johansson, Sixten Borg, Katarina Eeg-Olofsson, Bo Palaszewski, Maria Svedbo Engström, Soffia Gudbjörnsdottir, Stefan Franzén, Janeth Leksell

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Investigating Correlation Between Gut Microbiota and Rheumatoid Arthritis Subtypes by Mendelian Randomization by Jiaqi Wu, Yao Peng, Ruimin Tian, Hao Yu, Huating Hu, Qingchun Huang, Youhua Xu, Liang Liu, Hudan Pan

“…Notably, no significant heterogeneity (<i>p</i> > 0.05) or pleiotropy (<i>p</i> > 0.05) was detected in the analysis of the significant MR estimates. <b>Conclusions</b>: Our study suggested significant associations between several gut bacteria and RA subtypes, indicating a potential microbial influence on RA development. …”
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Intrauterine inflammation exposure may increase the risk of late-onset sepsis in premature infants: a retrospective cohort study by Xiafang Chen, XinYu Zhang, Ru Xue, Lanlan Mi, Ye Liu, Guoqing Zhang, Jun Bu, Fei Bei

“…Logistic regression analysis was used to assess the impact of cytokines and white blood cell counts on the incidence of LOS. …”
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Selection of excipients for the purpose of creating an intranasal gel of interleukin-1 receptor antagonist β (IL-1ra) by B. S. Burlaka, I. F. Bielenichev, V. V. Hladyshev, E. V. Suprun, H. P. Lysianska

“…According to published data, the researchers found that the receptor antagonist of interleukin-1 (IL-1ra) exhibits neuroprotective properties in brain ischemia by blocking excess IL-1 and activating the anti-inflammatory cytokine cascade, in order to reduce local inflammation and neuronal loss. …”
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