Factors Associated With the Severity of Chronic Constipation Among Japanese University Students by Nhu Thi Hanh Vu, Huong Tu Lam, Shunsuke Miyauchi, Naoki Ishiuchi, Atsuo Yoshino, Yoshie Miyake, Shiro Oka, Yuri Okamoto, Duc Trong Quach, Shinji Tanaka, Toru Hiyama

“…Multivariate logistic regression analysis was performed to determine independent risk factors. …”
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Stated preferences of adolescents and young adults for sexual and reproductive health services in Africa: a systematic review by Melaku Birhanu Alemu, Richard Norman, Jaya Dantas, Daniel Gashaneh Belay, Tsegaye G. Haile, Gavin Pereira, Gizachew A. Tessema

“…However, these insights reflect data from a limited range of African countries.…”
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Sleep Disorders and Reproductive Health: Mechanisms, Consequences, and Potential Interventions by Magdalena Rosa-Bończak Rosa, Patrycja Marta, Filip Maciej Huzarski, Klaudia Anna Pawełek, Gabriela Monika Ferfecka, Agata Ossolińska, Natalia Morawiecka, Lucyna Stolarska, Oliver Carlton, Weronika Kłosowicz

“…Materials and Methods This article is based on an analysis of scientific literature concerning the impact of sleep disturbances on reproductive health, utilizing data from databases such as PubMed, Frontiers, and Google Scholar. …”
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Repurposing Mouthwashes: Antifungal and Antibiofilm Abilities of Commercially Available Mouthwashes Against <i>Candida</i> spp. by Marie Maziere, Paulo Rompante, José Carlos Andrade, Beatriz S. F. De Oliveira, Mariana C. Alves, Celia Fortuna Rodrigues

“…Indeed, the solution to emerging infectious diseases may no longer lie in costly new drug development but rather in unlocking the untapped potential of existing substances. …”
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Genomic insights about the effect of sodium-glucose cotransporter 2 inhibitors: a systematic review by Pavitraa Saravana Kumar, Yogapriya Chidambaram, G. Shree Devi, Vettriselvi Venkatesan, Ramesh Sankaran, Nagendra Boopathy Senguttuvan, Thanikachalam Sadagopan, Dorairaj Prabhakaran

“…Studies were included if they explored the genomic or molecular impacts of SGLT2 inhibitors in HF. Data extraction and analysis focused on gene expression changes, circulating biomarkers, and potential genomic mechanisms.ResultsOf the 258 identified studies, three met the inclusion criteria. …”
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The Association between Inflammation and Pulse Wave Velocity in Dyslipidemia: An Evidence-Based Review by Amilia Aminuddin, Md Rizman M. L. M. Lazim, Adila A. Hamid, Chua K. Hui, Mohd H. Mohd Yunus, Jaya Kumar, Azizah Ugusman

“…This supports the involvement of inflammation in the development of AS in dyslipidemia.…”
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Predictors of Success in Horizontal Strabismus Surgery: Insights from a Prospective Study by Aurellia Valmai Tjujitno, Reni Prastyani, Joni Susanto, Rozalina Loebis, Luki Indriaswati, Lely Retno Wulandari

“…The International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) for Macintosh version 27.0 was used for data analysis. Results: This study reviewed the medical records of 17 research samples (n=17). …”
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Advance care planning for vulnerable older adults within an Accountable Care Organization: study protocol for the IMPACT randomised controlled trial by Jennifer Gabbard, NM Pajewski, Kathryn E Callahan, Ajay Dharod, Kristie Foley, Keren Ferris, Adam Moses, Carl Grey, Jeff Williamson

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Comparative evaluation of hybrid and individual models for predicting soybean yellow mosaic virus incidence by Yunish Khan, Vinod Kumar, Amel Gacem, Anurag Satpathi, Parul Setiya, Kumari Surbhi, Ajeet Singh Nain, Dinesh Kumar Vishwakarma, Ahmad J. Obaidullah, Krishna Kumar Yadav, Ozgur Kisi

“…Specifically, six multivariate models Stepwise Multiple Linear Regression (SMLR), Artificial Neural Networks (ANN), Least Absolute Shrinkage and Selection Operator (LASSO), Ridge Regression (RR), Elastic Net (ELNET), and SMLR_ANN both direct and with Principal Component Analysis (PCA)-were developed using 20 years of data (2001 to 2020) to predict the severity of soybean disease in Pantnagar, Uttarakhand. …”
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Extracellular vesicles from human breast cancer-resistant cells promote acquired drug resistance and pro-inflammatory macrophage response by Patrick Santos, Caroline P. Rezende, Renan Piraine, Bianca Oliveira, Francielle B. Ferreira, Vinicius S. Carvalho, Rodrigo T. Calado, Matteo Pellegrini, Fausto Almeida

“…In addition, we show evidence that resistant EVs may downregulate immune system factors to evade detection and block cell death by apoptosis in sensitive breast cancer cells. Our data also reveals that human macrophages in contact with resistant EVs trigger a pro-inflammatory cytokine secretion profile, an effect that may be helpful for future immunotherapy studies.DiscussionThese findings are the first transcriptome-wide analysis of cells exposed to resistant EVs, supporting that resistant EVs are associated with the acquired drug resistance process during chemotherapy by modulating different aspects of sensitive cancer cells that coffer the chemoresistance.…”
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The Role of NK Cells in Cancer Immunotherapy: Mechanisms, Evasion Strategies, and Therapeutic Advances by Paula Morcillo-Martín-Romo, Javier Valverde-Pozo, María Ortiz-Bueno, Maurizio Arnone, Laura Espinar-Barranco, Celia Espinar-Barranco, María Eugenia García-Rubiño

“…<b>Methods:</b> A comprehensive literature review was conducted, prioritizing peer-reviewed studies from the last decade on NK cell biology, tumor immune evasion, and immunotherapeutic applications. The analysis includes data from preclinical models and clinical trials evaluating NK cell expansion strategies, cytokine-based stimulation, and CAR-NK cell therapy developments. …”
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Large decrease in syringe distribution following the introduction of fentanyl in King County, Washington by Sara N. Glick, Joe Tinsley, Laura Pritchard Wirkman, Apoorva Mallya, Peter Cleary, Matthew R. Golden, Thomas Fitzpatrick

“…Material and Methods: We collected routine program data from three SSPs in King County, Washington. …”
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Intraspecific Differentiation of <I>Francisella tularensis</I> Strains Using Molecular-Genetic Methods. Complex Approach by N. A. Osina, D. A. Sitmbetov, O. A. Morozov, E. G. Bulgakova, A. V. Osin, S. S. Chekmareva, E. V. Sazanova, A. M. Senichkina, O. Yu. Lyashova, T. A. Polunina, Ya. M. Krasnov, Z. L. Devdariani, S. A. Shcherbakova

“…The intraspecific identification of tularemia agent strains was carried out using the “F. tularensis-4c” system; analysis of the variability of the RD1 differentiation region, the sdhA gene, by applying the disk diffusion method using disks with erythromycin. …”
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Genome-wide identification of characteristic nucleotide fragments for surveillance and subtype typing of influenza A viruses by Jingze Liu, Xu Zhang, Shicheng Li, Xiao Ding

“…These findings provide a valuable resource for molecular surveillance and diagnostic assay development.…”
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Supporting parent capacity to manage pain in young children with cancer at home: Co‐design and usability testing of the PainCaRe app by Lindsay A. Jibb, William Liu, Jennifer N. Stinson, Paul C. Nathan, Julie Chartrand, Nicole M. Alberts, Elham Hashemi, Tatenda Masama, Hannah G. Pease, Lessley B. Torres, Haydee G. Cortes, Susan Kuczynski, Sam Liu, Henry La, Michelle A. Fortier

“…App usability and acceptability were evaluated using the validated System Usability Scale and a thematic analysis of app testing sessions and interviews. Iterative testing sessions were conducted until data saturation. …”
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Exploring the spectral patterns of chemical elements in soils through proximal VIS-NIR spectroscopy and ML (a pilot study: Armenia) by A. Medvedev, G. Tepanosyan, S. Asmaryan, R. Avetisyan, V. Muradyan, I. Sereda, A. Gevorgyan, K. Davtyan, L. Sahakyan

“…Correlation analysis of the content of these macro components and their spectral reflectance values shows that they vary in spectral patterns. …”
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Prognostic Nomogram for Predicting Survival in Asian Patients With Small‐Cell Lung Cancer: A Comprehensive Population‐Based Study and External Verification by Yuanli Xia, Jingjing Qu, Yufang Wang, Yanping Zhu, Jianying Zhou, Jianya Zhou

“…Methods The SEER database supplied data on 661 Asian SCLC patients, who were then divided into training and internal validation sets through a random selection process. …”
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Assessing the Heat Transfer Modeling Capabilities of CFD Software for Involute-Shaped Plate Research Reactors by Cezary Bojanowski, Ronja Schönecker, Katarzyna Borowiec, Kaltrina Shehu, Julius Mercz, Frederic Thomas, Yoann Calzavara, Aurelien Bergeron, Prashant Jain, Christian Reiter, Jeremy Licht

“…The results were benchmarked against the Sieder–Tate correlation and experimental data from historic studies. The codes produced consistent results, showing good agreement with the empirical correlation of Sieder–Tate and the experimental measurements. …”
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Influence of latitude, host body size and host body weight on helminth species richness and abundance in two Neotropical marsupials by Bruna Silva Cirino, Sócrates Fraga da Costa Neto, Thiago dos Santos Cardoso, Arnaldo Maldonado Júnior, Rosana Gentile

“…Moreover, host intrinsic factors may be more relevant to endoparasite occurrence and development than latitude because they directly influence the parasite niche.…”
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Role of postoperative radiotherapy in pT3N0 rectal cancer: A risk‐stratification system based on population analyses by Yun‐xia Huang, Yan‐zong Lin, Jin‐luan Li, Xue‐qing Zhang, Li‐rui Tang, Qing‐yang Zhuang, Fei‐fei Lin, Xi‐jin Lin, Jun‐xin Wu

“…In this review of the Surveillance, Epidemiology, and End Results database (2010‐2014), we analyzed the data of pT3N0 rectal cancer patients who had not undergone neoadjuvant radiotherapy. …”
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