Early detection of emerging SARS-CoV-2 Variants from wastewater through genome sequencing and machine learning by Xiaowei Zhuang, Van Vo, Michael A. Moshi, Ketan Dhede, Nabih Ghani, Shahraiz Akbar, Ching-Lan Chang, Angelia K. Young, Erin Buttery, William Bendik, Hong Zhang, Salman Afzal, Duane Moser, Dietmar Cordes, Cassius Lockett, Daniel Gerrity, Horng-Yuan Kan, Edwin C. Oh

“…To build our model, we sequence 3659 wastewater samples collected over two years from urban and rural locations in Southern Nevada. We then develop a multivariate independent component analysis (ICA)-based pipeline to transform mutation frequencies into independent sources. …”
Get full text

Application of Convolutional Neural Networks in an Automatic Judgment System for Tooth Impaction Based on Dental Panoramic Radiography by Ya-Yun Huang, Yi-Cheng Mao, Tsung-Yi Chen, Chiung-An Chen, Shih-Lun Chen, Yu-Jui Huang, Chun-Han Chen, Jun-Kai Chen, Wei-Chen Tu, Patricia Angela R. Abu

“…With the advancement of artificial intelligence (AI), the integration of clinical data and AI-driven analysis presents significant potential for supporting medical applications. …”
Get full text

Emergence of scaling in dockless bike-sharing systems for bike choice behavior by Ruiqi Li, Te Bai, Ankang Luo, Yu Yang, Linyuan Lü, Jingfang Fan, Yongping Zhang, Gang Lu, H Eugene Stanley

Get full text

Method to analyse and quantify the propensity of hair dyes to desorb from human hair fibre by Kristina Hetherington, Alenka Tidder, Bethany J. Tack, Meryem Benohoud, Dan Nowlan, Anwar Zahar, Xiaoguang Li, Darcy Prater, Jeanna C. Zguris, Tanu Tokle, Christopher M. Rayner, Richard S. Blackburn

“…Through screening of common back-extraction methods used in analysis of dyed textile artefacts, a new back-extraction methodology has been developed and adapted for application on dyed hair using a 2:1 (v/v) water:pyridine solvent system. …”
Get full text

Physical education curriculum systematizing based on action research: a collaborative network between teacher-researchers from public schools in Quixadá — Ceará, Brazil by Rener Victor Oliveira de Souza, Maurício Teodoro de Souza, Luciano Nascimento Corsino, Willian Lazaretti da Conceição, Carla Ulasowicz, Luciana Venâncio, Luciana Venâncio, Luiz Sanches Neto, Luiz Sanches Neto

“…Our qualitative itinerary has action research as a method of intervention, including class observations, group meetings and field diary. Data has been analyzed through thematic analysis, characterizing a collaborative network between participants. …”
Get full text

Upregulation of long noncoding RNA zinc finger antisense 1 enhances epithelial–mesenchymal transition in vitro and predicts poor prognosis in glioma by Qiao-Li Lv, Shu-Hui Chen, Xue Zhang, Bao Sun, Lei Hu, Qiang Qu, Yuan-Tao Huang, Gui-Hua Wang, Yan-Ling Liu, Ying-Ying Zhang, Hong-Hao Zhou

“…Multivariate Cox regression analysis provided a clue that, probably, zinc finger antisense 1 level could serve as an independent prognostic factor for glioma. …”
Get full text

Structure and dynamics of the interaction of Delta and Omicron BA.1 SARS-CoV-2 variants with REGN10987 Fab reveal mechanism of antibody action by Ekaterina N. Lyukmanova, Evgeny B. Pichkur, Dmitry E. Nolde, Milita V. Kocharovskaya, Valentin A. Manuvera, Dmitriy A. Shirokov, Daria D. Kharlampieva, Ekaterina N. Grafskaia, Julia I. Svetlova, Vassili N. Lazarev, Anna M. Varizhuk, Mikhail P. Kirpichnikov, Zakhar O. Shenkarev

“…Three-dimensional variability analysis reveals high mobility of the RBD/Fab regions. …”
Get full text

A phase separation-related gene signature for prognosis prediction and immunotherapy response evaluation in gastric cancer with targeted natural compound discovery by Yanjuan Jia, Yuanyuan Ma, Zhenhao Li, Wenze Zhang, Rukun Lu, Wanxia Wang, Chaojun Wei, Chunyan Wei, Yonghong Li, Xiaoling Gao, Tao Qu

“…Results By Integrating analysis of the differential expression dataset from TCGA-STAD (n = 407, 375 tumor/32 normal) with prognosis-related dataset and PS-related dataset, we identified 78 candidate genes and developed a robust 21-gene risk prediction model. …”
Get full text

Functional Liver Imaging Score to Predict Clinically Significant PHLF for Hepatocellular Carcinoma After Resection by Zheng X, Zhang Y, Huang H, Luo N

“…Multivariate analysis identified FLIS, major resection and ALBI score as independent predictors of clinically significant PHLF, and a model combining these three variables predicted failure in the development cohort (AUC 0.746, 95% CI 0.673– 0.820) and internal validation cohort (AUC 0.717, 95% CI 0.595– 0.838). …”
Get full text

Impact of a comprehensive healthy lifestyle on pre-diabetes risk and glycaemic control: insights from NHANES 2005–2018 by Hongmei Xu, Wenyan Xu, Yingying Li, Jiayin Qin, Dandan Sun, Di Bao, Chun Mu, Qiuling Xing

Get full text

Features of “Inverted” Educational Resources for Distance Learning of Pupils by D. A. Barkhatova, A. L. Simonova, P. S. Lomasko, L. B. Khegay

“…Based on a theoretical analysis of psychological, pedagogical, methodological literature on the topic of research and modern statistical data demonstrating the level of readiness and motivation of students for independent distance learning, the paper describes the features of the structure and content of “inverted” educational resources, built taking into account the cognitive and psychosocial characteristics of modern “digital” generation. …”
Get full text

An exploratory assessment of GPT-4o and GPT-4 performance on the Japanese National Dental Examination by Masaki Morishita, Hikaru Fukuda, Shino Yamaguchi, Kosuke Muraoka, Taiji Nakamura, Masanari Hayashi, Izumi Yoshioka, Kentaro Ono, Shuji Awano

Get full text

Interplay between the gut microbiome and typhoid fever: insights from endemic countries and a controlled human infection model by Philip M. Ashton, Leonardos Mageiros, James E. Meiring, Angeziwa Chunga-Chirambo, Farhana Khanam, Sabina Dongol, Happy Banda, Abhilasha Karkey, Lorena Preciado-Llanes, Helena Thomaides-Brears, Malick Gibani, Nazmul Hasan Rajib, Nazia Rahman, Prasanta Kumar Biswas, Md Amirul Islam Bhuiyan, Sally Kay, Kate Auger, Olivier Seret, Nicholas R. Thomson, Andrew J. Pollard, Stephen Baker, Buddha Basnyat, John D. Clemens, Christiane Dolecek, Sarah J. Dunstan, Gordon Dougan, Robert S. Heyderman, Virginia E. Pitzer, Firdausi Qadri, Melita A. Gordon, Kathryn E. Holt, Thomas C. Darton, STRATAA Study Group

“…The putative protection provided by microbiome SCFA metabolism was supported by data from a controlled human infection model conducted in a UK population, in which participants who did not develop typhoid fever following ingestion of S. …”
Get full text

Nécropoles multipolaires et élaboration d’un nouveau modèle socio-politique au premier âge du Fer : réflexions à partir des sites du Camp de l’Église Sud à Flaujac-Poujols (Lot) et... by Antoine Dumas

“…The chronological information may then be considered. The topographical development of each site is shown to be consistent with the hypothesis that several distinct groups of burials existed, meaning that both sites developed following a multipolar pattern. …”
Get full text

Unveiling biomarkers via plasma metabolome profiling for diabetic macrovascular and microvascular complications by Zhixi Li, Yuhan Ren, Feng Jiang, Kai Zhang, Xuan Meng, Yingfeng Zheng, Mingguang He

“…Methods This study included 333,870 participants from the UK Biobank (n = 115,078) and FinnGen Biobank (n = 218,792). The initial analysis utilizing longitudinal data from 7,711 patients with diabetes was used to screen 249 plasma metabolites associated with diabetic vascular complications. …”
Get full text

Methylation and gene expression patterns in adamantinomatous craniopharyngioma highlight a panel of genes associated with disease progression-free survival by Junier Marrero-Gutiérrez, Ana Carolina Bueno, Ana Carolina Bueno, Clarissa Silva Martins, Rui Milton Patrício Silva-Júnior, Antônio Carlos dos Santos, Marcelo Volpon Santos, Luiz Eduardo Wildemberg, Ximene Lima da Silva Antunes, Monica R. Gadelha, Ayrton Custodio Moreira, Ricardo Zorzetto Nicoliello Vêncio, Sonir Roberto R. Antonini, Margaret de Castro

“…Functional enrichment analysis highlighted key roles in synaptic modulation, nervous system development, cell adhesion, as well as pathways linked to RAS signaling, GTPase activity, and membrane potential regulation.ConclusionAlthough clinical characteristics were largely comparable between the clusters, ACP-B patients exhibited shorter median progression-free survival, suggesting a more aggressive phenotype. …”
Get full text

Organic bistable memory devices utilizing PMMA polymer matrix-based ZnOC60 core-shell QDs nanocomposites by Jaeho Shim, Jinseo Park, Seok-Ho Seo, Ju Hee You, Dong Ick Son

“…The devices achieved a high ON/OFF current ratio of 7.46 × 103, demonstrated exceptional cycling endurance exceeding 1.5 × 104 cycles, and exhibited long-term retention surpassing 1.2 × 105 s. Detailed analysis of current-voltage (I-V) data highlighted Fowler-Nordheim (F-N) tunneling as a key mechanism facilitating efficient memory operation. …”
Get full text

Results of monitoring probable cases of acute severe hepatitis of unknown etiology in children in Мoscow in 2022 by М. А. Sayfullin, L. N. Mazankova, A. Yu. Rtischev, E. N. Abramova, N. A. Antypyat, N. N. Zvereva, O. A. Ivanova, M. A. Kolikova, A. A. Rakhalina, K. K. Rumyantseva, A. A. Samkov, I. N. Tyurin

“…Еpidemiological data (age, gender, parenteral manipulations, contacts with patients, travel abroad), clinical (fever, jaundice, etc.), laboratory parameters were assessed. …”
Get full text

Nomogram predicting overall survival of stage IIIB non‐small‐cell lung cancer patients based on the SEER database by Ziye Li, Pingfan Shi, Chenge Qin, Wen Zhang, Shumeng Lin, Tiansheng Zheng, Ming Li, Lihong Fan

“…The nomogram was evaluated for predictive ability using receiver operating characteristic (ROC) curves, decision curve analysis curve (DCA), and clinical impact curve (CIC). …”
Get full text

Prediction of summer precipitation via machine learning with key climate variables：A case study in Xinjiang, China by Chenzhi Ma, Junqiang Yao, Yinxue Mo, Guixiang Zhou, Yan Xu, Xuemin He

“…To train the ML model, we used precipitation data from 1961 to 2012, whilst the forecast results from 2013 to 2017 were used for validation. …”
Get full text