Epstein–Barr virus and multiple sclerosis by A. I. Skliar, I. I. Torianyk, T. P. Osolodchenko, S. V. Ponomarenko

“…Taking into account current data on the biological properties of EBV and analyzing the role of this herpes virus in the pathogenesis of neurodegenerative diseases, this review was generated. …”
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Glycopattern comparison of sperm and exosomes from conventional in vitro fertilization and rescue intracytoplasmic sperm injection: Enhancing sperm motility through exosome‐mediate... by Muhammad Anas Ramzan, Zhedong Yang, Li Cao, Jinyuan Zhang, Fei Wu, Miaomiao Xin, Bo Guo, Lumin Wang, Lingyu Zhao, Yannan Qin, Chengcheng Liu

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Modeling of molecular weight changes of polysaccharides subjected to irradiation by Li Wang, Peiling Huang, Jianyong Huang, Huamu Xie, Xingyu Liu, Xinyi Liu, Qing Cai, Boon Chin Heng, Yuanli Huang, Qianqian Han, Zigang Ge

“…It was found that the molecular weight of HA decreases inversely with irradiation time or dose (R-squared: 0.71 - 0.96). Based on these data, a quantitative model was developed to predict the molecular weight of HA after irradiation sterilization, and its feasibility was validated through both theoretical analysis and experimental verification. …”
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Mapping of RORγt+ dendritic cells in human tissues establishes their preferential niche in adult lymph nodes by Silvia Lonardi, Francisco MA Bianchetto-Aguilera, Matilde Monti, Anna Di Matteo, Francesco Missale, Francesco Missale, Sara Picinoli, Mattia Bugatti, Martina Benedetti, Giorgia Ferrari, Marco A. Cassatella, Daniele Moratto, Stefania Zini, Valentina Agostini, Viola Savoldi, Luisa Lorenzi, Marco Chiarini, Fabio Facchetti, Shitong Wu, Alina Ulezko Antonova, Yizhou A. Liu, Marina Cella, Claudia Ghigna, Marco Colonna, William Vermi, William Vermi

“…Recent data in mouse and human have revealed non-T, non-ILC3 cell populations with antigen presenting features that express RORγt. …”
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Evaluation of the Therapeutic Potential of Traditionally-Used Natural Plant Extracts to Inhibit Proliferation of a HeLa Cell Cancer Line and Replication of Human Respiratory Syncyt... by Ellie N. Brill, Natalie G. Link, Morgan R. Jackson, Alea F. Alvi, Jacob N. Moehlenkamp, Morgan B. Beard, Adam R. Simons, Linden C. Carson, Ray Li, Breckin T. Judd, Max N. Brasseale, Emily P. Berkman, Riley K. Park, Sedna Cordova-Hernandez, Rebecca Y. Hoff, Caroline E. Yager, Meredith C. Modelski, Milica Nenadovich, Dhruvi Sisodia, Clayton J. Reames, Andreas G. Geranios, Sean T. Berthrong, Anne M. Wilson, Ashlee H. Tietje, Christopher C. Stobart

“…While none of the identified compounds were shown to induce significant impacts on HeLa cell proliferation, two of the compounds, (1S)-(-)-Borneol and 5-(hydroxymethyl)-furfural, identified in sage and spicebush, respectively, were shown to have antiviral activities. Our data suggest that several of the extracts tested exhibited either anti-proliferative or antiviral activity supporting future further analysis.…”
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The Application of Deep Learning for Lymph Node Segmentation: A Systematic Review by Jingguo Qu, Xinyang Han, Man-Lik Chui, Yao Pu, Simon Takadiyi Gunda, Ziman Chen, Jing Qin, Ann Dorothy King, Winnie Chiu-Wing Chu, Jing Cai, Michael Tin-Cheung Ying

“…The introduction of deep learning technologies offers new possibilities for improving the accuracy of lymph node image analysis. This study evaluates the application of deep learning in lymph node segmentation and discusses the methodologies of various deep learning architectures such as convolutional neural networks, encoder-decoder networks, and transformers in analyzing medical imaging data across different modalities. …”
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A searchable atlas of pathogen-sensitive lncRNA networks in human macrophages by Nils Schmerer, Harshavardhan Janga, Michelle Aillaud, Janina Hoffmann, Marina Aznaourova, Sarah Wende, Henrike Steding, Luke D. Halder, Michael Uhl, Fabian Boldt, Thorsten Stiewe, Andrea Nist, Lukas Jerrentrup, Andreas Kirschbaum, Clemens Ruppert, Oliver Rossbach, Evgenia Ntini, Annalisa Marsico, Chanil Valasarajan, Rolf Backofen, Uwe Linne, Soni S. Pullamsetti, Bernd Schmeck, Leon N. Schulte

“…Abstract Long noncoding RNAs (lncRNA) are crucial yet underexplored regulators of human immunity. Here we develop GRADR, a method integrating gradient profiling with RNA-binding proteome analysis, to map the protein interactomes of all expressed RNAs in a single experiment to study mechanisms of lncRNA-mediated regulation of human primary macrophages. …”
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A new ALK inhibitor overcomes resistance to first‐ and second‐generation inhibitors in NSCLC by Yue Lu, Zhenzhen Fan, Su‐Jie Zhu, Xiaoxing Huang, Zhongji Zhuang, Yunzhan Li, Zhou Deng, Lei Gao, Xuehui Hong, Ting Zhang, Li Li, Xihuan Sun, Wei Huang, Jingfang Zhang, Yan Liu, Baoding Zhang, Jie Jiang, Fu Gui, Zheng Wang, Qiyuan Li, Siyang Song, Xin Huang, Qiao Wu, Lanfen Chen, Dawang Zhou, Jianming Zhang, Cai‐Hong Yun, Liang Chen, Xianming Deng

“…Here, we develop XMU‐MP‐5 as a new‐generation ALK inhibitor to overcome crizotinib resistance mutations, including L1196M and G1202R. …”
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STRAIN LOCALIZATION PECULIARITIES AND DISTRIBUTION OF ACOUSTIC EMISSION SOURCES IN ROCK SAMPLES TESTED BY UNIAXIAL COMPRESSION AND EXPOSED TO ELECTRIC PULSES by V. A. Mubassarova, L. M. Bogomolov, A. S. Zakupin, I. A. Panteleev, O. B. Naimark

“…The above conclusions correlate with the statistical model of a solid body with defects which is developed in ICMM [Panteleev et al., 2011, 2012, 2013a].…”
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Political Order and Nomadic Life in Iran: From the Afsharid Period to the End of the Qajar Dynasty by Shahram Gholami, Siavash Gholipour

“…Data analysis was conducted through the systematic organization of the collected information. …”
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DOSE-ESCALATED EXTERNAL BEAM RADIOTHERAPY DURING HORMONO-RADIOTHERAPY FOR PROSTATE CANCER by Yu. V. Gumenetskaya, Yu. S. Mardynskiy, I. A. Gulidov, O. B. Karyakin, V. S. Chaykov

“…The introduction of modern technologies of conformal external beam radiotherapy (EBRT) into clinical practice for the treatment of prostate cancer requires proper quality assurance measures as well as a careful analysis of both the efficacy and toxicity data of treatments. …”
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Interpretable XGBoost model identifies idiopathic central precocious puberty in girls using four clinical and imaging features by Lu Tian, Yan Zeng, Helin Zheng, Jinhua Cai

“…Conclusions An accurate and interpretable ML-based model has been developed to aid clinicians in the diagnosis of ICPP, assisting in clinical decision-making.…”
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Cancellation of cloud shadow effects in the absorbing aerosol index retrieval algorithm of TROPOMI by V. J. H. Trees, V. J. H. Trees, P. Wang, P. Stammes, L. G. Tilstra, D. P. Donovan, D. P. Donovan, A. P. Siebesma

“…Hence, the quantification of the cloud shadow impact requires the analysis of large data sets. Here we use the cloud shadow detection algorithm DARCLOS to detect cloud shadow pixels in the TROPOMI absorbing aerosol index (AAI) product over Europe during 8 months. …”
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Ecological health assessment of Tibetan alpine grasslands in Gannan using remote sensed ecological indicators by Zeyu Du, Xibin Ji, Jane Liu, Wenyue Zhao, Zhibin He, Jiachang Jiang, Qiyue Yang, Liwen Zhao, Jinlong Gao

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Evaluation of the impact of the state of emergency during the COVID-19 pandemic on childhood immunizations in Benguela Province, Angola by Tadatsugu Imamura, Keiji Mochida, Balogun Olukunmi, Lino Tchicondingosse, Pedro Sapalalo, Ketha Rubuz Francisco, Ai Aoki, Akira Ishiguro, Kenji Takehara

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Burden of Breast Cancer Disease Among Older Adults in Asian Countries From 1990 to 2021 by Min Zhang, Chao Ye, Jing Qiu, Min Zhao, Meimei Cui, Jiayi Chen, Jingjing Jia, Wenjie Yan, Liling Zhu, Limei Luo

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A second horizon scan of biogeography: Golden Ages, Midas touches, and the Red Queen by Michael N Dawson, Jan C. Axmacher, Carl Beierkuhnlein, Jessica L. Blois, Bethany A. Bradley, Anna F. Cord, Jürgen Dengler, Kate S. He, Lawrence R. Heaney, Roland Jansson, Miguel D. Mahecha, Corinne Myers, David Nogués-Bravo, Anna Papadopoulou, Björn Reu, Francisco Rodríguez-Sánchez, Manuel J. Steinbauer, Alycia Stigall, Mao-Ning Tuanmu, Daniel G. Gavin

“…<p>Are we entering a new ‘Golden Age’ of biogeography, with continued development of infrastructure and ideas? We highlight recent developments, and the challenges and opportunities they bring, in light of the snapshot provided by the 7^th biennial meeting of the International Biogeography Society (IBS 2015). …”
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Clinical characteristic of isolated thrombocytopenia in patients with bone marrow failure-related germline variants: a retrospective study from a single centre by Nanxi Dong, Jingjie Dong, Chuanao Xin, Peicheng Wang, Yaonan Hong, Rudan Zheng, Zexing Sun, Qi Liu, Yingying Shen, Xiawan Yang, Yiping Shen, Jianping Shen, Baodong Ye, Yuhong Zhou, Dijiong Wu

“…This study compares prognosis and clinical features of isolated thrombocytopenia in patients with ITGV-BMFsand those with classic ITP.Methods The clinical data of patients diagnosed with ITGV-BMFs were retrospectively analyzed and compared with those of patients with classic ITP from August 2018 to February 2024. …”
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Deep learning-driven modality imputation and subregion segmentation to enhance high-grade glioma grading by Jiabin Yu, Qi Liu, Chenjie Xu, Qinli Zhou, Jiajun Xu, Lingying Zhu, Chen Chen, Yahan Zhou, Binggang Xiao, Lin Zheng, Xiaofeng Zhou, Fengming Zhang, Yuhang Ye, Hongmei Mi, Dongping Zhang, Li Yang, Zhiwei Wu, Jiayi Wang, Ming Chen, Zhirui Zhou, Haoyang Wang, Vicky Y. Wang, Enyu Wang, Dong Xu

“…Materials and methods A retrospective analysis was conducted using data from 1,251 patients in the BraTS2021 dataset as the main cohort and 181 clinical cases collected from a medical center between April 2013 and June 2018 (51 years ± 17; 104 males) as the external test set. …”
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From Flanders to Portugal: A Portuguese Painter in Pursuit of Prestigious Flemish Painting—Materials and Techniques Compared Through an Analytical Approach by Vanessa Antunes, António Candeias, José Mirão, Sara Valadas, Ana Cardoso, Maria José Francisco, Alexandra Lauw, Marta Manso, Maria Luísa Carvalho

“…Together, these findings reveal that Jorge Afonso’s workshop developed a distinct Portuguese method—rooted in Flemish practices disseminated by Quentin Metsys—yet adapted to local materials and aesthetic priorities.…”
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