Global HPV vaccination programs and coverage rates: a systematic reviewResearch in context by Jingjing Han, Li Zhang, Yuqing Chen, Yuelun Zhang, Le Wang, Ruyu Cai, Minge Li, Yuxin Dai, Le Dang, Hongda Chen, Lan Zhu

“…Methods: In this study, we performed a comprehensive search of the PubMed and Embase databases (from their inception to February 28, 2025), websites, the WHO database, to identify HPV vaccination policies and coverage rate data from all 194 WHO member states. Studies included in our analysis reported population-based HPV vaccination coverage rates. …”
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Leveraging machine learning to optimize cooling tower efficiency for sustainable power generation by M. A. Mujtaba, Muhammad Adeel Munir, Muhammad Akhtar, Bilal Mahmood, Talha Ansar, Zeeshan Khawar, Shayan Khalid, Abdul Basit, Saud Jamil, M. A. Kalam, Fayaz Hussain, Chiranjib Bhowmik

“…United Nations Sustainable Development Goal 7 is about ensuring access to clean and affordable energy, which is a key factor in the development of society. …”
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Optimizing energy production from livestock biogas networks in southern Brazil: economic and environmental perspectives by Phillip Schmedeman, Karthik Rajasekaran, Afreen Siddiqi, Cristian Junge, Chun Hern Tan, Janaina Pasqual Lofhagen, Felipe S Marques, Olivier de Weck

“…A non-linear bi-objective optimization model is developed, using validated field data from Southern Brazil, to maximize economic (profit) and environmental (GHG savings) objectives. …”
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Unraveling Parkinson's disease motor subtypes: A deep learning approach based on spatiotemporal dynamics of EEG microstates by Lin Meng, Deyu Wang, Jun Ma, Yu Shi, Hongbo Zhao, Yanlin Wang, Qingqing Shi, Xiaodong Zhu, Dong Ming

“…A deep learning model was developed to classify PD motor subtypes where spatial variability and electrode location data were incorporated into the analysis. …”
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SBML Level 3: an extensible format for the exchange and reuse of biological models by Sarah M Keating, Dagmar Waltemath, Matthias König, Fengkai Zhang, Andreas Dräger, Claudine Chaouiya, Frank T Bergmann, Andrew Finney, Colin S Gillespie, Tomáš Helikar, Stefan Hoops, Rahuman S Malik‐Sheriff, Stuart L Moodie, Ion I Moraru, Chris J Myers, Aurélien Naldi, Brett G Olivier, Sven Sahle, James C Schaff, Lucian P Smith, Maciej J Swat, Denis Thieffry, Leandro Watanabe, Darren J Wilkinson, Michael L Blinov, Kimberly Begley, James R Faeder, Harold F Gómez, Thomas M Hamm, Yuichiro Inagaki, Wolfram Liebermeister, Allyson L Lister, Daniel Lucio, Eric Mjolsness, Carole J Proctor, Karthik Raman, Nicolas Rodriguez, Clifford A Shaffer, Bruce E Shapiro, Joerg Stelling, Neil Swainston, Naoki Tanimura, John Wagner, Martin Meier‐Schellersheim, Herbert M Sauro, Bernhard Palsson, Hamid Bolouri, Hiroaki Kitano, Akira Funahashi, Henning Hermjakob, John C Doyle, Michael Hucka, SBML Level 3 Community members, Richard R Adams, Nicholas A Allen, Bastian R Angermann, Marco Antoniotti, Gary D Bader, Jan Červený, Mélanie Courtot, Chris D Cox, Piero Dalle Pezze, Emek Demir, William S Denney, Harish Dharuri, Julien Dorier, Dirk Drasdo, Ali Ebrahim, Johannes Eichner, Johan Elf, Lukas Endler, Chris T Evelo, Christoph Flamm, Ronan MT Fleming, Martina Fröhlich, Mihai Glont, Emanuel Gonçalves, Martin Golebiewski, Hovakim Grabski, Alex Gutteridge, Damon Hachmeister, Leonard A Harris, Benjamin D Heavner, Ron Henkel, William S Hlavacek, Bin Hu, Daniel R Hyduke, Hidde de Jong, Nick Juty, Peter D Karp, Jonathan R Karr, Douglas B Kell, Roland Keller, Ilya Kiselev, Steffen Klamt, Edda Klipp, Christian Knüpfer, Fedor Kolpakov, Falko Krause, Martina Kutmon, Camille Laibe, Conor Lawless, Lu Li, Leslie M Loew, Rainer Machne, Yukiko Matsuoka, Pedro Mendes, Huaiyu Mi, Florian Mittag, Pedro T Monteiro, Kedar Nath Natarajan, Poul MF Nielsen, Tramy Nguyen, Alida Palmisano, Jean‐Baptiste Pettit, Thomas Pfau, Robert D Phair, Tomas Radivoyevitch, Johann M Rohwer, Oliver A Ruebenacker, Julio Saez‐Rodriguez, Martin Scharm, Henning Schmidt, Falk Schreiber, Michael Schubert, Roman Schulte, Stuart C Sealfon, Kieran Smallbone, Sylvain Soliman, Melanie I Stefan, Devin P Sullivan, Koichi Takahashi, Bas Teusink, David Tolnay, Ibrahim Vazirabad, Axel von Kamp, Ulrike Wittig, Clemens Wrzodek, Finja Wrzodek, Ioannis Xenarios, Anna Zhukova, Jeremy Zucker

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The Junction Between nsp1β and nsp2 in the Porcine Reproductive and Respiratory Syndrome Virus Genome Is a New Site for the Insertion and Expression of Foreign Genes by Changguang Xiao, Yafang Lin, Hailong Zhang, Zongjie Li, Ke Liu, Beibei Li, Donghua Shao, Yafeng Qiu, Zhiyong Ma, Jianchao Wei

“…In addition, rPRRSV-SH01-eGFP can be used as a reporter virus for rapid detection of neutralizing antibodies against PRRSV through a fluorescent focus unit reduction-based assay. These data demonstrate that the junction between nsp1β and nsp2 is a new site that is suitable for the insertion and expression of foreign genes, providing a new option to express and deliver foreign genes using PRRSV-based vectors for different purposes, such as the development of multi-valent vaccines against PRRSV and other porcine viruses.…”
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Identification of the sweet orange (Citrus sinensis) bHLH gene family and the role of CsbHLH55 and CsbHLH87 in regulating salt stress by Yinqiang Zi, Mengjie Zhang, Xiuyao Yang, Ke Zhao, Tuo Yin, Ke Wen, Xulin Li, Xiaozhen Liu, Hanyao Zhang

“…Abstract Salt stress is one of the primary environmental stresses limiting plant growth and production and adversely affecting the growth, development, yield, and fruit quality of Citrus sinensis. bHLH (basic helix‐loop‐helix) genes are involved in many bioregulatory processes in plants, including growth and development, phytohormone signaling, defense responses, and biosynthesis of specific metabolites. …”
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Major histocompatibility complex I upregulation in clear cell renal cell carcinoma is associated with increased survival by Rishi R. Sekar, Claire M. De La Calle, Dattatraya Patil, Sarah A. Holzman, Yoram Baum, Umer Sheikh, Jonathan H. Huang, Adeboye O. Osunkoya, Brian P. Pollack, Haydn T. Kissick, Kenneth Ogan, Viraj A. Master

“…Patients that did not develop recurrence during the study period had higher MHCI expression (mean positivity score 0.83) than those that did develop recurrence (mean positivity score 0.78), but this difference was not significant (t test, p = 0.079). …”
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Potential evaluation of saline aquifers for the geological storage of carbon dioxide: A case study of saline aquifers in the Qian-5 member in northeastern Ordos Basin by Yan Li, Peng Li, Hong-jun Qu, Gui-wen Wang, Xiao-han Sun, Chang Ma, Tian-xing Yao

“…This study calculated the technical control capacities of CO2 of the saline aquifers in the fifth member of the Shiqianfeng Formation (the Qian-5 member) based on the statistical analysis of the logging and the drilling and core data from more than 200 wells in the northeastern Ordos Basin, as well as the sedimentary facies, formation lithology, and saline aquifer development patterns of the Qian-5 member. …”
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Dynamic regulation of Rgs16 and its correlation with Neuregulin1 expression in acute and chronic nerve injury by Marina García-Bejarano, Marina García-Bejarano, Marina García-Bejarano, Riccardo Aucello, Riccardo Aucello, Federica Zen, Federica Zen, Marwa El Soury, Marwa El Soury, Francesca Cordero, Jesús M. de la Fuente, Isabelle Perroteau, Giulia Ronchi, Giulia Ronchi, Giovanna Gambarotta, Giovanna Gambarotta

“…To examine the role of Rgs16 in chronic nerve degeneration, its expression was evaluated in a pathological model of Charcot-Marie-Tooth disease type-1A (CMT1A), a chronic demyelinating peripheral neuropathy. Analysis of publicly available RNA sequencing data from sciatic nerves of wild-type and CMT1A rats during development showed a significant upregulation of Rgs16 in transgenic rats at P18. …”
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Construction of an early childhood caries risk prediction model based on the oral microbiome: a nested case‒control study by Teck-Ek Ho, Yuan-Meng Yang, Wen-Jia Gu, Wen Meng, Xin-Yu Chen, Si-Cheng Wu, Edward Chin Man Lo, Fei Li, Hai-Xia Lu

“…The alpha diversity analysis showed statistically significant differences in the Simpson and Shannon indices between the H2H and H2C groups (P < 0.05), and the beta diversity analysis revealed statistically significant differences between the H2H group and the H2C and C2C groups. …”
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Diseño de un Software de Intermediación de Comunicación para Sistemas Distribuidos de Tiempo Real Críticos en Java by Daniel Tejera, Alejandro Alonso, Miguel A. de Miguel

“…The use of Java in the development of high-integrity systems requires strict development and testing techniques.However, neither RTSJ nor its profiles provide facilities to develop distributed real-time applications. …”
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Pragmatic Approach to Hepatocellular Carcinoma Diagnosis in High-Incidence, Resource-Limited Settings in Africa by Gregory D. Kirk, Sara Nsibirwa, Jim K. Aizire, Redeat L. Assefa, Antonio Bandala-Jacques, Jackson Orem, Tongai Maponga, Moussa Seydi, Gilles Wandeler, Amir Mohareb, David L. Thomas, Fred Okuku, Emmanuelle Ochola, Ponsiano Ocama

“…The purpose of this study was to develop a pragmatic HCC diagnostic strategy for such settings.METHODSWe evaluated standardized protocol-collected data on clinical, ultrasonographic, biochemical, and pathological criteria in a multisite study of 649 suspected HCC cases in Uganda. …”
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Radiomic prediction for durable response to high‐dose methotrexate‐based chemotherapy in primary central nervous system lymphoma by Haoyi Li, Mingming Xiong, Ming Li, Caixia Sun, Dao Zheng, Leilei Yuan, Qian Chen, Song Lin, Zhenyu Liu, Xiaohui Ren

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Benchmarking reinforcement learning and accurate modeling of ground source heat pump systems: Intelligent strategy using spiking recurrent neural network combined with spider WASP... by Sana Qaiyum, Kashif Irshad, Mohamed E. Zayed, Salem Algarni, Talal Alqahtani, Asif Irshad Khan

“…Finally, statistical analysis was used to evaluate the robustness of the developed SWO-SRNN models. …”
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Modeling and Control of a 3DOF Robot Manipulator Using Artificial Fuzzy-Immune FOPID Controller by Worod Adris Shutnan, Nora Ahmed Mohammed, Faris Asaad Abdulmunem, Ali Hamzah Najim, Mustafa Yahya Hassan, Naglaa F. Soliman, Abeer D. Algarni

“…These days, with the development of technology, using robots has become very common in various fields. …”
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Choose Your Own Adventure: Using Twine for Gamified Interactive Learning in Veterinary Anaesthesia by José I. Redondo, M. Reyes Marti-Scharfhausen, Agustín Martínez-Albiñana, Ariel Cañón-Pérez, Álvaro J. Gutiérrez-Bautista, Jaime Viscasillas, E. Zoe Hernández-Magaña

“…Following a workshop for second- to fourth-year students of the Degree in Veterinary Sciences, an anonymous survey assessed the module’s effectiveness. Quantitative data were analysed descriptively, while qualitative feedback was processed through a hybrid AI–human thematic analysis. …”
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Qualitative assessment of proposed visual key information pages for informed consent by Krista E. Cooksey, Eliana Goldstein, Clara Lee, Jessica Mozersky, Kimberly A. Kaphingst, Victor Catalan Gallegos, Mary C. Politi

“…We coded written transcripts inductively and deductively based on the capability, opportunity, and motivation to change behavior (COM-B) framework. Data were analyzed using content analysis and organized thematically. …”
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Surveillance for Infection and Colonization due to Candida spp. at a Tertiary Referral Hospital in Botswana: 2022-2024 by Ms Teresia Gatonye, Ms Janet John-Thubuka, Mr Tichaona Machiya, Ms Tlhalefo Dudu Ntereke, Mr Tshiamo Zankere, Mrs Chimwemwe V Tembo, Ms Boingotlo Gopolang, Dr Naledi Mannathoko, Ms Miriam Mwamba, Prof Nelesh Govender, Ms Sabelle Jallow, Ms Rudzani Mashau, Ms Ruth Mpembe, Ms Silondiwe Nzimande, Dr Melissa Richard-Greenblatt, Dr David Goldfarb, Dr Ebbing Lautenbach, Dr Jonathan Strysko

“…This study aimed to analyze surveillance data to characterize patterns of Candida BSI and colonization among hospitalized patients in Botswana. …”
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Uptake of the Hepatitis B Vaccine Among Pre‐Service Health Professionals in Rwanda by Bivegete Kenny Ntwari, Felix K. Rubuga, Silene Jolie Uwingabiye, Vincent Dushimimana, Jean Baptiste Hategekimana, Serieux Cyubahiro, Ivan Steve Rwema, Daniel Ukwishatse, Patrick Karakwende, Jean Muhire, Adolphe Ndikubwimana, Theoneste Ntakirutimana, Pierre Dukuziyaturemye, Didas Mugisha, Canisius Gasana, Edith Musabwa, Felicien Irafasha, Celestin Banamwana, Frank Gasana, Idrissa Nkurunziza, Deborah Oluwaseun Shomuyiwa, Don Eliseo Lucero‐Prisno III

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