Smilebright^RO—Study Protocol for a Randomized Clinical Trial to Evaluate Oral Health Interventions in Children by Ruxandra Sava-Rosianu, Guglielmo Campus, Vlad Tiberiu Alexa, Octavia Balean, Ruxandra Sfeatcu, Alice Murariu, Alexandrina Muntean, Daniela Esian, Constantin Daguci, Simona Olaru-Posiar, Vanessa Bolchis, Antonia Ilin, Ramona Dumitrescu, Berivan Laura Rebeca Buzatu, Mariana Postolache, Nicoleta Toderas, Roxana Oancea, Daniela Jumanca, Atena Galuscan

“…Clinical outcomes will be evaluated using the caries incidence rate; this will be calculated for each tooth as the unit of analysis and evaluated using a multi-step approach. …”
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Patient preferences and shared decision making for the traditional Chinese medicine treatment of lung cancer: A discrete choice experiment study by Yue Teng, Yan Wei, Yingyao Chen, Juntao Yan, Shimeng Liu, Fuming Li, Shiyi Bao, Yanfeng Ren, Liu Liu, Yi Yang

“…The empirical data analyses of patients were performed using mixed logit models. …”
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Gastrointestinal Infection Before Immune Checkpoint Inhibition Hinders Treatment Efficacy and Increases the Risk of Colitis by Malek Shatila, Kian Abdul‐Baki, Andres Urias Rivera, Kei Takigawa, Irene Jeong‐Ah Lee, Andrew Sullivan, Tanvi Gupta, Linfeng Lu, Raakhi Menon, Ayesha Khan, Hamza Salim, Elliot Baerman, Carolina Colli Cruz, Cristina Natha, Varun Vemulapalli, Garrett Coleman, Krishnavathana Varatharajalu, Christopher Fan, Pablo Okhuysen, Anthony J. Olszanski, Yan Zhou, Hao Chi Zhang, Mehnaz Shafi, Yinghong Wang

“…Patients' demographic, IMC, and GI infection–related clinical data were collected. Results Thirty‐four of the 1132 patients (3.0%) included in the analysis had GI infections before ICI therapy. …”
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REHABILITATION EFFECT OF CORRECTION OF ERECTILE DYSFUNCTION IN PATIENTS WHO UNDERWENT RADICAL PROSTATECTOMY FOR PROSTATE CANCER by A. T. Asratov, I. V. Vinogradov, B. R. Gvasaliya, A. A. Kachmazov, A. G. Kochetov, Yu. V. Samsonov, N. V. Sitnikov, A. O. Tolkachev, A. A. Kostin

“…The material of the study was analysis of the questionnaire data of 30 patients with PC with the postoperative ED before the postoperative period and after the falloprosthesis. …”
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Neutrophil and neutrophil-lymphocyte ratios as predictors of clinical characteristics in patients with Lymphangioleiomyomatosis by Lulu Yang, Lulu Yang, Lulu Yang, Liting Huang, Liting Huang, Liting Huang, Yingquan Luo, Siying Ren, Siying Ren, Siying Ren

“…Differences between the two groups were compared, and significantly different indicators were further analyzed.ResultsA total of 78 patients with LAM were included in the study, 42 of them developed pneumothorax from registration to the end of follow-up, and 36 did not develop pneumothorax. …”
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Epidemiological trends and predictions of urinary tract infections in the global burden of disease study 2021 by Yining He, Jing Zhao, Lanhui Wang, Chao Han, Ruxue Yan, Peiqi Zhu, Tianyang Qian, Siyao Yu, Xiaolin Zhu, Weiming He

“…The estimated annual percentage change was used to depict temporal trends, whereas Pearson correlation analysis explore its correlation with the human development index (HDI), the SDI, and age-standardised rates (ASRs). …”
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Dynamic Alterations in DNA Methylation of CD4+ T Cells and Macrophages in a Murine Model of Tuberculous Pleural Infection Induced by BCG Vaccination by Ming‐Ming Shao, Qing‐Yu Chen, Xin Zhang, Shu‐Feng Dong, Rui‐Qi Wei, Huan‐Zhong Shi, Feng‐Shuang Yi

“…This study analyzed DNA methylation and transcriptome data from macrophages and CD4+ T cells from pleural lavage fluid of BCG‐induced tuberculous pleurisy mouse models at specific time points (Days 0, 1, 7, and 14). …”
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Effect of social play deprivation on stress sensitivity in response to social and non-social challenges by E. J. Marijke Achterberg, Jose G. Lozeman-van ‘t Klooster, Tara C. Pimentel, Anastasija Aleksić, Judith C. M. J. Hendriks, Sanne Nijhof, C. Kors van der Ent, Heidi M. B. Lesscher

“…DiscussionTogether our results indicate that, except for subtle differences in play behaviour in a social challenging condition, play deprivation did not result in altered corticosterone responses to the different stressors. Our data add to the existing knowledge about the impact of social play for the development of resilient and social behaviour later in life.…”
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Impact of anthropogenic pollution on the health of the population of East Kazakhstan: Environmental risks and dependent diseases by Gulnaz Sadykanova, Sanat Kumarbekuly, Kulzipa Dakieva, San Orazova, Bagdat Karmenova, Zhamal Igissinova, Anargul Sharipkhanova, Gauhar Nurzhan

“…Data sources were PubMed, Google Scholar, and other relevant resources. …”
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Construction of a risk prediction model for falls in elderly lung cancer patients with sarcopenia by Qing Wang, Qing Wang, Xiao Han, Jun Zhang, Jun Zhang, Mengying Hu, Mengying Hu, Jiaojiao Xu, Qiongqiong Ai, Hequn Wei, Jiao Yu, Haiping Ma

“…A logistic regression predictive model was developed on the basis of independent risk factors.ResultsThe incidence of falls among elderly lung cancer patients with sarcopenia was 19.94%. …”
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A systematic scoping review on utility of cytomorphometry in the detection of dysplasia in oral potentially malignant disorders by Monal Yuwanati, Amol Gadbail, Shailesh Gondivkar, Sachin C. Sarode, Ravi Dande, Shubhangi Mhaske, Satayjit Tekade, Sandeep Kumar Pathak

“…Objective computer-based quantitative cytomorphometry technique was developed in last few decades to overcome its limitation. …”
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Risk factors and predictive models for post-operative moderate-to-severe mitral regurgitation following transcatheter aortic valve replacement: a machine learning approach by Zhenzhen Li, Jianing Fan, Jiajun Fan, Jiaxin Miao, Dawei Lin, Jingyan Zhao, Xiaochun Zhang, Wenzhi Pan, Daxin Zhou, Junbo Ge

“…Methods We retrospectively analyzed data from patients who underwent TAVR at our center between August 2014 and August 2023. …”
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Global dengue epidemic worsens with record 14 million cases and 9000 deaths reported in 2024 by Najmul Haider, Mohammad Nayeem Hasan, Joshua Onyango, Masum Billah, Sakirul Khan, Danai Papakonstantinou, Priyamvada Paudyal, Md Asaduzzaman

“…Dengue, caused by the dengue virus (DENV), is the fastest-growing mosquito-borne disease worldwide. We utilised monthly data on dengue cases and deaths reported through the World Health Organisation's (WHO) global surveillance system for the period of 1st January to 31st December 2024. …”
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Lead bioaccumulation in human breast cancer tissue is associated with DNA instability and cell death resistance by Manuel Scimeca, Erica Giacobbi, Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Francesca Servadei, Daniel R. S. Middleton, Julia Bischof, Maria Paola Scioli, Giorgio Modesti, Eleonora Candi, Gerry Melino, Alessandro Mauriello

“…Biopsy samples from 26 breast cancer patients were collected for molecular investigations (DNA and RNA sequencing), histological analysis, and the assessment of Pb concentration by ICP-MS. …”
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Linking PFOS exposure to chronic kidney disease: A multimodal study integrating epidemiology, network toxicology, and experimental validation by Xulei Zuo, Shiyi Tan, Yuxi Zhang, Cong Zhang, Li Ma, Xiaoyu Hou, Wei Wang, Rongli Sun, Lihong Yin, Yuepu Pu, Juan Zhang

“…NHANES data (n = 9119) were analyzed to examine the association between serum PFOS levels and CKD prevalence. …”
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Addressing the challenges and constraints of social protection policies for Peruvian women domestic workers: the ANITA project study protocol by Maria Lazo-Porras, Maria Kathia Cardenas, Nathaly Aya Pastrana, Christopher Meaney, Andrew David Pinto, Archna Gupta, María Sofía Cuba-Fuentes, Silvana Perez-Leon, Janeth Tenorio-Mucha, Sebastián García, Jill Portocarrero, Karina Romero Rivero, David Vera Tudela, Ayu Pinky Hapsari, Viviana Cruzado

“…We use a sequential mixed-methods design organised in four phases: (1) secondary data analysis (n=4216): using two Peruvian national surveys to characterise working conditions, health status and access to healthcare; (2) face-to-face survey (n=448): with DWs in three cities, using respondent-driven sampling to further characterise working and health conditions and to identify factors that influence knowledge of and access to social protection policies; (3) qualitative interviews (n=30–46): with DWs, leaders of DW organisations, employers and policymakers to gather different perspectives on the facilitators and barriers to access to social protection policies; and (4) deliberative dialogues (n=14–26): with DW, leaders of DW organisations, employers, policymakers and academics to identify key barriers to the implementation of social protection policies and to develop recommendations for overcoming these barriers.Ethics and dissemination Phase 1 and Phase 2 received ethical clearance from Universidad Peruana Cayetano Heredia in Peru and Unity Health Toronto in Canada. …”
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Understanding and simulating cropland and non-cropland burning in Europe using the BASE (Burnt Area Simulator for Europe) model by M. Forrest, J. Hetzer, M. Billing, M. Billing, S. P. K. Bowring, S. P. K. Bowring, E. Kosczor, L. Oberhagemann, L. Oberhagemann, O. Perkins, O. Perkins, D. Warren, D. Warren, F. Arrogante-Funes, K. Thonicke, T. Hickler, T. Hickler

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Calcium and silicon nanofertilizers improved morphological attributes and fatty acid composition in olive; an insight to synergistic interaction between these elements by Javad Erfani-Moghadam, Abdolkarim Zarei

“…The fatty acid composition of olive oil was analyzed by gas chromatography (GC). The data sets were subjected to the normal test and the analysis of variance (ANOVA) was conducted using SAS software (version 9.4) and mean comparison was conducted using the Least Significant Difference (LSD) test at α = 0.05 significance level. …”
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Is the Mineral Content of Muscle Tissue (<i>Longissimus Lumborum</i>) in Cattle Finished During the Rainy Season in the Eastern Amazon Influenced by Different Farming Systems? by Ana Paula Damasceno Ferreira, Jamile Andréa Rodrigues da Silva, Miguel Pedro Mourato, José António Mestre Prates, Thomaz Cyro Guimarães de Carvalho Rodrigues, André Guimarães Maciel e Silva, Andrea Viana da Cruz, Adriny dos Santos Miranda Lobato, Welligton Conceição da Silva, Elton Alex Corrêa da Silva, Antônio Marcos Quadros Cunha, Vanessa Vieira Lourenço-Costa, Éder Bruno Rebelo da Silva, Tatiane Silva Belo, José de Brito Lourenço-Júnior

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Effects of abiotic stress and hormones on the expressions of five 13-CmLOXs and enzyme activity in oriental melon (Cucumis melo var. makuwa Makino) by Jie-ying LIU, Chong ZHANG, Qi SHAO, Yu-fan TANG, Song-xiao CAO, Xiao-ou GUO, Ya-zhong JIN, Hong-yan QI

“…In addition, promoter analysis revealed that motifs of the five genes participate in gene expression regulated by hormones and stresses. …”
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