Synergistic Antibacterial and Antibiofilm Activity of the MreB Inhibitor A22 Hydrochloride in Combination with Conventional Antibiotics against Pseudomonas aeruginosa and Escherich... by Anastasia Kotzialampou, Efthymia Protonotariou, Lemonia Skoura, Afroditi Sivropoulou

“…In the era of antibiotic resistance, the bacterial cytoskeletal protein MreB is presented as a potential target for the development of novel antimicrobials. Combined treatments of clinical antibiotics with anti-MreB compounds may be promising candidates in combating the resistance crisis, but also in preserving the potency of many conventional drugs. …”
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Training antenatal care providers to deliver brief problem-solving therapy in rural Ethiopia: a developmental evaluation by Roxanne C Keynejad, Adiyam Mulushoa, Tesera Bitew, Louise M. Howard, Charlotte Hanlon, Sharon Markless

“…We triangulated 18 qualitative interviews with women intervention recipients, ANCPs, mental health specialist trainer/supervisors and research staff, with documentary data. We employed reflexive thematic analysis before ‘peer review’ of our interpretations by a female Ethiopian research assistant. …”
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Histological study of potassium 2-((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazole-3-yl)thio)acetate (PKR-173) corrective influence on the chickens liver state in the condition of... by R. O. Shcherbyna, Ye. V. Vashchyk

“…Conclusions. Analysis of the pathological process quantitative characteristics, which developed in the chicken liver after tetracycline administration and corrective influence of the investigated drugs on it, has shown that the PKR-173 compound significantly reduced the manifestations of all the pathological features detected for testing compared to control pathology. …”
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Shock digitalisation of education: The perception of participants of the educational process by V. L. Nazarov, D. V. Zherdev, N. V. Averbukh

“…As a result of the survey conducted, more than 24,500 original responses were received and processed. The data obtained were compared with the results of secondary studies (primarily, with the monitoring studies of the Higher School of Economics).Results. …”
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Gender Peculiarities of Postresuscitation in the Expression of Brain-Derived Neurotrophic Factor (BDNF) by M. Sh. Avrushchenko, I. V. Ostrova, A. V. Grechko

“…Statistic processing of data was performed with the aid of Statistica 7.0 using Kolmogorov-Smirnov λ test, Mann-Whitney U test, and Student's t-test.Results. …”
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Satellite imagery pre-processing and feature extraction for the mapping of coastal ecosystems using Google Earth Engine: A workflow for practitioners by Ahmad Badruzzaman, Prawesti Wulandari, Sainal Sainal, Matthew Ashley, Susan Jobling, Melanie C. Austen, Radisti A. Praptiwi

“…The use of Google Earth Engine (GEE) is increasingly common in geospatial analysis of satellite images for various environmental management purposes due to its easy accessibility and capabilities to support complex pre-processing and mining of geographic data. …”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…Main outcome measures Mortality, patient and carer quality of life, cognition, activities of daily living. Data sources Clinical trial. Results A total of 284 participants were recruited, 132 to the PEFECT-ER intervention arm and 150 to the control arm, had good retention in the study and provided data for analysis. …”
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Predict potential pharmacological mechanisms of Ling-gui-Zhu-gan Decoction in treating unstable angina pectoris using liquid chromatography-mass spectrometry and network pharmacolo... by Xiaopeng Li, Xiaopeng Li, Tan Xue, Tan Xue, Panpan Zhang, Panpan Zhang, Fengyu Dong, Fengyu Dong, Han Li, Han Li, Jing Yao, Haiying Huang, Lizhuang Zhang, Ruixin Liu, Ruixin Liu, Ruixin Liu, Ruixin Liu, Ruixin Liu, Ruixin Liu, Ruixin Liu, Ruixin Liu

“…This integrative analysis identified three key active compounds—naringenin, glycyrrhizin, and calycosin—and three core targets: TNF, EGFR, and PTGS2.DiscussionThe analytical method established in this study effectively delineates the chemical profile and index component transfer dynamics of LGZGD preparation intermediates, providing essential data for the development of both liquid and solid dosage forms. …”
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Abstract 082: Angiographic Features and Treatment Results of Dural Arteriovenous Fistulas Cognitive Impairment by Sebastian A. Sanchez, Linder Wendt, Chen Ching‐Jen, Minako Hayakawa, Edgar Samaniego, Jason Sheehan, Louis Kim, Issac Abecassis, Michael Levitt, Michael Meyer, Ridhima Guniganti, Akash Pabaney, Giuseppe Lanzino, Enrico Giordan, Waleed Brinjikji, Diederik Bulters, Santiago Ortega, Andrew Durnford, Gregory Zipfel, W Fox, Colin Derdeyn, Jessica Smith, Bradley Gross, Sepideh Amin‐Hanjani, Ali Alaraj

“…We conducted a retrospective analysis of the CONDOR database, focusing on patients diagnosed with dAVFs‐CI. …”
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New Advances of the P-SBAS Approach for an Efficient Parallel Processing of Large Volumes of Full-Resolution Multitemporal DInSAR Interferograms by Manuela Bonano, Pasquale Striano, Muhammad Yasir, Sabatino Buonanno, Francesco Casu, Claudio De Luca, Adele Fusco, Yenni Lorena Belen Roa, Ivana Zinno, Maria Virelli, Michele Manunta, Riccardo Lanari

“…Furthermore, it is also shown that the implemented processing solution easily allows us to deal with SAR data acquired through the Stripmap and TOPS modes. …”
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Quasiexperimental intervention study protocol to optimise the use of new antibiotics in Spain: the NEW_SAFE project by Jesús Rodríguez-Baño, Zaira R Palacios-Baena, Clara M Rosso-Fernández, Pilar Retamar, Lucia Valiente de Santis, Natalia Maldonado, Irene Borreguero, Carmen Herrero-Rodríguez, Salvador López-Cárdenas, Franciso J Martínez-Marcos, Andrés Martín-Aspas, Patricia Jiménez-Aguilar, Juan J Castón, Guillermo Ojeda-Burgos, M Pilar Aznarte-Padial, Julia Praena-Segovia, Juan E Corzo-Delgado, M Ángeles Esteban-Moreno

“…Second, a quasiexperimental intervention study will be developed with an interrupted time-series analysis (2020–2021). …”
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Foot screening and customized health education program for patients with diabetic peripheral neuropathy: A nurse-led, real-world observational study by Shuhong Liu, Hexiao Ding, Dandan Li, Fen Lu, Gumei Luo, Yujin He, Hui Li, Xiuhong Zeng, Kaixin Li, Dong-E Gong, Xiling Hu, Yanming Chen, Xubin Yang

“…Patients with incomplete medical data, transfers, critical conditions or death, existing foot ulcers or amputations, bedridden or uncooperative individuals (5,470 individuals) were excluded, and a total of 4,721 individuals were selected for analysis. …”
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IL‐27 produced during acute malaria infection regulates Plasmodium‐specific memory CD4+ T cells by Maria Lourdes Macalinao, Shin‐Ichi Inoue, Sanjaadorj Tsogtsaikhan, Hirotaka Matsumoto, Ganchimeg Bayarsaikhan, Jiun‐Yu Jian, Kazumi Kimura, Yoshiaki Yasumizu, Tsuyoshi Inoue, Hiroki Yoshida, Julius Hafalla, Daisuke Kimura, Katsuyuki Yui

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The innovation and local culture in the production of specialty coffee in Short Food Supply Chains and their impacts on environmental sustainability by Amanda dos Santos Negreti Campos, Giuliana Aparecida Santini Pigatto, Renato Dias Baptista, Timóteo Ramos Queiroz

“…This is a qualitative-quantitative research, with multiple case studies. Data was collected through semi-structured interview observation and documents, and analysis was carried out using Fisher's Exact Test. …”
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Declawing in Cat is associated with neuroplastic sensitization and long-term painful afflictions by Mathieu LaChance, Colombe Otis, Tristan Juette, Jérôme R. E. del Castillo, Aliénor Delsart, Maxim Moreau, Beatriz P. Monteiro, Aude Castel, Bertrand Lussier, Johanne Martel-Pelletier, Jean-Pierre Pelletier, Eric Troncy

“…However, little is known on how post-declaw pain develops and affects feline well-being. Existing data often fail to account for other sources of chronic pain, such as osteoarthritis (OA), which affects most aging cats. …”
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Research on the charging periods of the ultra-shallow play in front of the Hashan area, northwestern margin of the Junggar Basin by WANG Qianjun, ZHOU Jian, ZHANG Faqiang, YU Hongzhou, WU Qianqian, LU Hongli, LIU Qingxin, ZHOU Yu, CHENG Ming, YAN Jianzhao, LYU Yanfang

“…Quantitative grain fluorescence (QGF) analysis was utilized to track hydrocarbon migration pathways and accumulation dynamics. …”
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Spatiotemporal Dynamics of Retrogressive Thaw Slumps in the Shulenanshan Region of the Western Qilian Mountains by Yu Zhou, Qingnan Zhang, Guoyu Li, Qingsong Du, Dun Chen, Junhao Chen, Anshuang Su, Miao Wang, Xu Wang, Benfeng Wang

“…However, spatiotemporal changes in RTS distribution and development in mid- to low-latitude permafrost regions are not well understood. …”
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Long-term impact of sevoflurane exposure on behavioural and neurocognitive outcomes in preschool children: protocol for a prospective cohort study by Zhichao Li, Hui Zheng, Shuai Li, Youzhuang Zhu, Xuanyuan Pan, Ruiying Fu, Linhui Ma, Jun Chai

“…Background The use of sevoflurane, a commonly used paediatric anaesthetic, raises concerns about potential long-term neurotoxic effects on behavioural and neurocognitive development, particularly during critical neurodevelopmental stages in preschool children. …”
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The impact of METTL3 on bladder cancer through m6A modification: a potential therapeutic target and prognostic biomarker by Dong Wen, Pengcheng Fu, Geliu Shuai, Yuebin Wang, Shengxin Yu, Huiquan Liu, Wei Wan, Junrong Zou, Junrong Zou, Xiaofeng Zou, Xiaofeng Zou, Xiaofeng Zou

“…Through the in-depth analysis of METTL3, we hope to provide new ideas and directions for the early diagnosis, prognostic evaluation, and the development of novel treatment strategies for BCa.…”
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Factors associated with chronic calcineurin inhibitor nephrotoxicity in children with minimal-change disease by Bei Jin, Ziji Lu, Cheng Cheng, Yuxin Pei, Lizhi Chen, Zhihui Yue, Aihua Lin, Shicong Yang, Ying Mo, Xiaoyun Jiang

“…Risk factors for chronic CNI nephrotoxicity included persistent nephrotic-range proteinuria for more than 30 days during CNI treatment, increased urinary NAG level, and CNI resistance. Multivariate analysis revealed that increased urinary NAG level and CNI resistance were the independent risk factors for chronic CNI nephrotoxicity in children with MCD.Conclusion MCD children who developed CNI resistance were susceptible to chronic CNI nephrotoxicity. …”
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