Identifying the factors affecting the growth of the employees of the country's property and documents registration organization by Najmeh Ahmadi, Kolsoum Nami, Nader Ghourchian, Parivash Jafari

“…Data analysis was done using open and axial coding method. …”
Get full text

Assessment of UAV Imageries for Estimating Growth Vitality, Yield and Quality of Hop (<i>Humulus lupulus</i> L.) Crops by Jana Řeřicha, Matěj Kohútek, Věra Vandírková, Karel Krofta, František Kumhála, Jitka Kumhálová

“…Based on statistical analysis it was concluded that in terms of yield assessment, spectral indices can explain hop yields up to 61%, with better results being achieved in the later stages of growth development. …”
Get full text

AWARENESS AND TREATMENT SPECIFICS OF STATIN THERAPY IN PERSONS WITH VARIOUS CARDIOVASULAR RISK: THE STUDY ESSE-RF by S. A. Shalnova, A. D. Deev, V. A. Metelskaya, S. E. Evstifeeva, O. P. Rotar, Yu. V. Zhernakova, S. А. Boytsov, Yu. A. Balanova, N. V. Gomyranova, A. E. Imaeva, A. V. Kapustina, A. V. Kontsevaya, O. A. Litinskaya, M. N. Mamedov, G. A. Muromtseva, R. G. Oganov, E. I. Suvorova, M. B. Khudyakov, E. I. Baranova, A. O. Konradi, E. V. Shlyakhto, V. A. Ilin, R. A. Kasimov, A. A. Shabunova, K. N. Kalashnikov, O. N. Kalachikova, O. A. Kondakova, A. V. Popov, N. A. Ustinova, O. G. Azarin, N. I. Babenko, L. V. Bondartsov, E. V. Minakov, A. E. Khvostikova, G. I. Furmenko, S. V. Nedogoda, A. A. Ledyaeva, E. V. Chumachek, N. V. Kulakova, M. V. Mokshina, V. A. Nevzorova, L. V. Rodionova, N. V. Shestakova, O. A. Belova, O. A. Nazarova, S. V. Romanchuk, O. A. Shutemova, V. S. Kaveshnikov, R. S. Karpov, V. N. Serebryakova, I. A. Trubacheva, A. I. Aristov, Yu. I. Grinshtein, L. K. Danilova, A. A. Evsyukov, D. S. Kaskaeva, A. A. Kosinova, M. M. Petrova, R. R. Ruf, N. V. Topolskaya, V. V. Shabalin, E. N. Shmatova, O. L. Barbarash, G. V. Artamonova, A. E. Skripchenko, E. V. Indukaeva, T. A. Mulerova, S. A. Maksimov, N. V. Cherkass, M. V. Tabakaev, Ya. V. Danilchenko, I. R. Basyrova, E. N. Isaeva, V. Yu. Kondratenko, R. A. Libis, E. A. Lopina, D. V. Safonova, S. K. Gutnova, T. M. Gatagonova, G. V. Tolparov, S. A. Gudkova, D. V. Duplyakov, N. A. Cherepanova, A. Yu. Efanov, I. V. Medvedeva, M. A. Storozhok, V. P. Shava, S. V. Shalaev

“…The data dictates necessity  of development  and implementation of specific educational programs for citizens, of physician improvement and availability of cheap but effective lipid-lowering medications.…”
Get full text

Assessing the safety and pharmacokinetics of the monoclonal antibodies, VRC07-523LS and PGT121 in HIV negative women in South Africa: study protocol for the CAPRISA 012A randomised... by Nigel Garrett, Sharana Mahomed, Edmund Capparelli, Cheryl Baxter, Nonhlanhla Yende Zuma, Tanuja Gengiah, Derseree Archary, Penny Moore, Natasha Samsunder, Dan H Barouch, John Mascola, Julie Ledgerwood, Lynn Morris, Salim Abdool Karim

“…The purpose of this trial is to provide safety, pharmacokinetic (PK) and functional activity data of VRC07-523LS and PGT121 when administered subcutaneously (SC) to young South African women. …”
Get full text

Relationship between composite dietary antioxidants index and growth indicators in children aged 3–12 years: results from two observational studies by Rui Wen, Huanting Pei, Jingyi Ren, Siqi Zhu, Simeng Qiao, Pui Yee Tan, Yunyun Gong, Min Yang, Junsheng Huo, Gangqiang Ding, Yuxia Ma

“…However, further research is needed to explore the underlying mechanisms of the synergistic effects of antioxidants on children's growth and development.…”
Get full text

Impact of Renin-Angiotensin System Inhibitors on Disease Characteristics in Patients with Localized Prostate Cancer Treated with Radical Prostatectomy: A European Association of Ur... by Nastasiia Artamonova, Mona Kafka, Laura Faiss, David Avetisyan, Ignacio Puche Sanz, Giulia La Bombarda, Gennaio Iacono, Fabio Zattoni, Eberhard Steiner, Caroline D’Elia, Armin Pycha, Michael Ladurner, Samed Jagodic, Giorgio Gandaglia, Isabel Heidegger

“…Background and objective: Collagen biosynthesis is intricately involved in the development and progression of solid tumors. Renin-angiotensin system inhibitors (RASi) impede TGF-β-mediated collagen synthesis in tumors by hindering activation of the angiotensin receptor. …”
Get full text

Deciphering the tumor immune microenvironment: single-cell and spatial transcriptomic insights into cervical cancer fibroblasts by Zhiheng Lin, Youwei Zhou, Zhenran Liu, Wenyang Nie, Hengjie Cao, Shengnan Li, Xuanling Li, Lijun Zhu, Guangyao Lin, Yanyu Ding, Yi Jiang, Zuxi Gu, Lianwei Xu, Zhijie Zhao, Huabao Cai

“…A prognostic model based on bulk RNA-seq data was constructed and validated through survival analysis, with correlations to immune microenvironment characteristics. …”
Get full text

The Spatiotemporal Evolution of Geo-Disaster Resilience in China and the Impact Mechanism of Environmental Governance by Hao Zhu, Xing Zhu, Yong Li, Yibin Ao, Xugong Jia, Panyu Peng, Mingyang Li, Jiayue Li

“…This study innovatively constructs a resilience assessment framework that considers extreme climate and geo-disaster intensity, integrating various statistical methods, including the Super-Efficiency Slacks-Based Measure Data Envelopment Analysis (SBM-DEA) model, spatial Markov chains, and methods such as Geodetector and the Geographically and Temporally Weighted Regression (GTWR), to reveal the spatiotemporal evolution of geo-disaster resilience in China from 2007 to 2022, while also analyzing the mechanisms through which environmental governance influences resilience and its spatiotemporal variations. …”
Get full text

Optical methods for the correction of postkeratoplastic ametropia by M.V. Sinitsyn, A.E. Terent’eva, T.G. Tolmacheva, N.A. Pozdeeva

“…It is necessary to develop a systematic approach to the personalized choice of an optical method for correcting postkeratoplastic ametropia, taking into account its effectiveness and safety, depending on the individual clinical and functional data of the patient. …”
Get full text

The Influence of Land‐Surface Conditions on the 2020–2021 Western US Drought by Yelin Jiang, Jason E. Smerdon, Richard Seager, Guiling Wang, Benjamin I. Cook, Cheng Zheng, Justin S. Mankin, A. Park Williams

“…Beyond the established influence of oceanic forcing and internal atmospheric variability, this study highlights the importance of land‐surface conditions in the development of the 2020–2021 WUS drought, using observational data analysis and novel numerical simulations. …”
Get full text

Prediction of the Immune Phenotypes of Bladder Cancer Patients for Precision Oncology by Hyuna Cho, Feng Tong, Sungyong You, Sungyoung Jung, Won Hwa Kim, Jayoung Kim

“…Bladder cancer (BC) is the most common urinary malignancy; however accurate diagnosis and prediction of recurrence after therapies remain elusive. This study aimed to develop a biosignature of immunotherapy-based responses using gene expression data. …”
Get full text

Identifying causative mechanisms linking early-life stress to psycho-cardio-metabolic multi-morbidity: The EarlyCause project. by Nicole Mariani, Alessandra Borsini, Charlotte A M Cecil, Janine F Felix, Sylvain Sebert, Annamaria Cattaneo, Esther Walton, Yuri Milaneschi, Guy Cochrane, Clara Amid, Jeena Rajan, Juliette Giacobbe, Yolanda Sanz, Ana Agustí, Tania Sorg, Yann Herault, Jouko Miettunen, Priyanka Parmar, Nadia Cattane, Vincent Jaddoe, Jyrki Lötjönen, Carme Buisan, Miguel A González Ballester, Gemma Piella, Josep L Gelpi, Femke Lamers, Brenda W J H Penninx, Henning Tiemeier, Malte von Tottleben, Rainer Thiel, Katharina F Heil, Marjo-Riitta Järvelin, Carmine Pariante, Isabelle M Mansuy, Karim Lekadir

“…This prevents a full understanding of causal pathways towards the shared risk of these diseases and the development of coordinated preventive and therapeutic interventions.…”
Get full text

Spatiotemporal Dynamics and Prediction of Habitat Quality Based on Land Use and Cover Change in Jiangsu, China by Ge Shi, Chuang Chen, Qingci Cao, Jingran Zhang, Jinghai Xu, Yu Chen, Yutong Wang, Jiahang Liu

“…Analyzing the spatiotemporal evolution characteristics of urban land use and habitat quality is crucial for the sustainable development of urban ecological environments. This study utilizes the land use data of Jiangsu Province for the years 2000, 2010, and 2020, applying the FLUS model to investigate the driving force behind land expansion and to simulate a prediction for the land use of 2030. …”
Get full text

Retinopathy of prematurity risk factors: Does human milk prevent retinopathy of prematurity? by Ayşe İpek Akyüz-Ünsal, Sema Oruç-Dündar, Ayşe Anık, İmran Kurt-Omurlu, Abdullah Barış Akcan, Mehtap Sagus, Sinan Bekmez, Duygu Güler, Özge Key, Münevver Türkmen

“… The aim of this study was to investigate the risk factors for Retinopathy of Prematurity (ROP) development and the potential effect of human breast milk among these factors. …”
Get full text

Preoperative and intraoperative risk factors for acute kidney injury after hip fracture surgery: a cohort retrospective study by Bassem I. Haddad, Abdulrahman A. Alhajahjeh, Abdelrahman Altarazi, Layla El-Amayreh, Mohammad Hamdan, Batool AlQuabeh, Waid Abd Ul Ghani, Randa I. Farah

“…We aimed to identify AKI risk after hip fracture surgery and the preoperative and intraoperative risk factors.Methodology We conducted a retrospective cohort study in a tertiary care hospital on adult patients who underwent surgery for hip fractures between January 2015 and August 2021. All clinical data were reviewed.Result A total of 611 patients were included (age = 76.44 ± 9.69 years). 126 (20.6%) of them developed AKI postoperatively. …”
Get full text

Designing a defensive silence failure model of creative employees in organizations by Azam Khosravi, karam khalili, Esfandyar Mohammadi

“…The collection tool in the qualitative part is open interviews with experts; and in the quantitative part, a researcher-made questionnaire. For data analysis, theme analysis and fuzzy Delphi technique were used in the qualitative part, and structural equations were used in the quantitative part. …”
Get full text

Identifying locally actionable strategies to increase participant acceptability and feasibility to participate in Phase I cancer clinical trials by Stephanie A. S. Staras, Easton N. Wollney, Lisa E. Emerson, Natalie Silver, Peter T. Dziegielewski, Marta D. Hansen, Gabriela Sanchez, Dalila D'Ingeo, Versie Johnson‐Mallard, Rolf Renne, Kristianna Fredenburg, Michael Gutter, Kendra Zamojski, Carla Vandeweerd, Carma L. Bylund

“…In addition to our qualitative data reflecting community voices, a community member reviewed the draft interview guide before data collection and both people with HNC and physicians aided interpretation of the findings.…”
Get full text

Risk factors for death among children aged 5–14 years hospitalised with pneumonia: a retrospective cohort study in Kenya by Grace Irimu, Morris Ogero, George Mbevi, David Gathara, Samuel Akech, Mike English, Liana Macpherson, Ambrose Agweyu, Mercy Chepkirui, Abraham Lagat, Sylvia Omoke, Cynthia Khazenzi, Basil Okola, Shadrack Muema, Paul Mwaniki, Lucas Malla, Emma Namulala, Juma Vitalis, Samuel Ng’arng’ar, Peter Aduro Kidaha, Rachel Inginia, Melab Musabi, Grace Ochieng, Lydia Thuranira, Magdaline Kuria, Samuel Otido, Esther Njiru, Charles Nzioki, Supa Tonje, Caren Emadau, Cecelia Mutiso, Peninah Mwangi, Christine Manyasi, David Kimutai, Celia Muturi, Agnes Mithamo, Anne Kamunya, Alice Kariuki, Grace Wachira

“…However, there are no validated guidelines for pneumonia management in older children and data to support their development are limited. We sought to understand risk factors for mortality among children aged 5–14 years hospitalised with pneumonia in district-level health facilities in Kenya.Methods We did a retrospective cohort study using data collected from an established clinical information network of 13 hospitals. …”
Get full text

Investigating neuropathological correlates of hyperactive and psychotic symptoms in dementia: a systematic review by Giulia Negro, Giulia Negro, Michele Rossi, Camillo Imbimbo, Alberto Gatti, Andrea Magi, Andrea Magi, Ildebrando Marco Appollonio, Ildebrando Marco Appollonio, Alfredo Costa, Alfredo Costa, Tino Emanuele Poloni, Tino Emanuele Poloni

“…Records were screened using PICO software, and data quality was assessed using the Newcastle-Ottawa Scale (NOS) and CARE guidelines. …”
Get full text

Safety, Tolerability and Pharmacokinetics of Sodium Tungstate (OXO-001) in Healthy Female Volunteers of Childbearing Age: A Randomized, Double-Blind, Dose-Finding, and Placebo-Cont... by Agnes Arbat, Ignasi Canals, Jimena Coimbra, Pol Molina-Perelló, Marta Llorens, Rosa Torres, Josep Perello, Marta Moral-Blanch, Rosa María Antonijoan, Joaquim Calaf

“…Background: Phase I study to assess the effects of single oral doses of 100, 200, and 300 mg/day of sodium tungstate (OXO-001) in healthy women of childbearing age.Materials and Methods: A randomized, double-blind, dose-finding, and placebo-controlled phase I study was con­ducted in healthy weight (body mass index [BMI] 18.5-24.9 kg/m2) and overweight (BMI 25 to ≥30 kg/m2) volunteers who received OXO-001 or placebo during a menstrual cycle (maximum 28 days). Data recorded were adverse events (AEs), vital signs, electrocardiogram (ECG), laboratory tests, pharmacokinetics (PK) parameters, and transvaginal ultrasound.Results: Thirty women were included in the safety analysis, and 29 completed the study. …”
Get full text