Nasopharyngeal necrosis following intensity-modulated radiation therapy of primary nasopharyngeal carcinoma—incidence rate and predictors of risk by Xing-Li Yang, Li Lin, Sha-Sha He, Dan-Wan Wen, Jia Kou, Yan Wang, Xue-Cen Wang, Yong Chen

“…Abstract Objectives This study aimed to investigate the incidence of post radiation nasopharyngeal necrosis (PRNN) in primary NPC after intensity modulated radiation therapy (IMRT) and identify the predictors of risk. Methods Data of 5798 NPC patients who received IMRT-based treatment between April 2009 and December 2015 were retrospectively reviewed. …”
Get full text

Mitochondrial DNA control region polymorphisms in Dongxiang blue-eggshell chicken and their evolutionary relatedness with nine domestic Wugu breeds by Zhang Xuedong, Li Qinghai, Zhang Chengxian, Chen Xianhui, Lou Lifeng, Wang Huanhuan

“…Nine other samples from domestic Wugu chicken breeds bred by our team or collected from the NCBI database were used for nucleotide sequence analysis. All breeds used in this study were recorded in Animal Genetic Resources in China and all collected data were analyzed using DNASTAR 5.0, DNASP 5.10, and MEGA 5.10 softwares.The results showed that the 534 bp mtDNA control region sequence of the Dongxiang blue-eggshell chicken had a G+C content of 43.1% and included 21 variable sites, of which 71.4% (15/21) were transitional and 28.6% (7/21) were transversional. …”
Get full text

Utility of dynamic contrast enhancement for clinically significant prostate cancer detection by Eric V. Li, Sai K. Kumar, Jonathan A. Aguiar, Mohammad R. Siddiqui, Clayton Neill, Zequn Sun, Edward M. Schaeffer, Anugayathri Jawahar, Ashley E. Ross, Hiten D. Patel

“…On multivariable analysis, PIRADS 3+ lesions were associated with higher csPCa rates compared to PIRADS 3− (3+ vs. 3−: OR 1.86, p = 0.024), but lower csPCa rates compared to PIRADS DWI 4 lesions (4 vs. 3+: OR 2.39, p < 0.001). csPCa rates were 19% (3−), 31% (3+), 41.5% (4−), 65.9% (4+), 62.5% (5−), and 92.3% (5+). bpMRI nomograms were non‐inferior to mpMRI nomograms in the development (n = 1410) and independent validation (n = 353) cohorts. …”
Get full text

Preferences for TB treatment and support delivery models among people living with TB in Eastern Cape, South Africa: a discrete choice experiment by Michael Strauss, Gavin George, Emma Lansdell, Kuhle Fiphaza, Andrew Medina‐Marino, Joseph Daniels

“…Mixed effects logistic regression models were used as primary analysis tools. Latent class analysis (LCA) was used to explore heterogeneity in preference structures. …”
Get full text

A study of acute toxicity of newly synthesized compound on adult hydrobiont Danio rerio by A. A. Safonov, Yu. V. Karpenko, Ye. H. Knysh

“…One of the main conditions for the development of a new drug is its low toxicity. Literature analysis has shown that 1,2,4-triazole-3-thione derivatives are low-toxic compounds and exhibit a wide range of pharmacological activities. …”
Get full text

The relationship between self-efficacy, learning burnout, willingness to fulfill the contract and empathy of rural-oriented tuition-waived medical students of China: a cross-sectio... by Xuewen Zhang, Guanqi Han, Chen Feng, Yuxuan Xu, Leyan Gao, Zhen Tan

“…SPSS 25.0 and AMOS 24.0 were used for statistical analysis and path analysis of the data. Results The willingness to fulfill the contract of rural-oriented tuition-waived medical students has a direct positive impact on self-efficacy (β = 0.11, P < 0.05) and empathy (β = 0.27, P < 0.001), and a significant direct negative impact on learning burnout (β = -0.25, P < 0.001). …”
Get full text

Novel non-curable resection prediction model for early colorectal cancer following endoscopic submucosal dissection based on inflammatory immune index by Xiunan Li, Lei Zhang, Biao Xu, Shu Ding, Jing Wang, Jing Wang, Yu Jia

“…We sought to explore the predictive ability of SII for non-curative resection of early colorectal cancer treated with ESD, and to establish a related predictive model.MethodsA retrospective analysis was performed on data from patients with early-stage colorectal cancer who underwent ESD in our hospital between January 2019 and December 2022. …”
Get full text

Optimization and Multimachine Learning Algorithms to Predict Nanometal Surface Area Transfer Parameters for Gold and Silver Nanoparticles by Steven M. E. Demers, Christopher Sobecki, Larry Deschaine

“…However, the expansion and testing of this model for nanoparticles of different metal composition is needed to develop a greater variety of nanosensors for medical and commercial applications. …”
Get full text

Patient-Specific Instrumentation Benefits for INBONE II Total Ankle Arthroplasty by Charlotte Jones BS, Allison Boden MD, Patricia Friedmann MS, Suzy Wang MS, Ricardo Villar MD, Constantine Demetracopoulos MD, Jonathan Deland MD, Elizabeth Cody MD, Matthew Conti MD, Jensen Henry MD, Scott Ellis MD

“…Chart review was performed to collect demographic data including primary surgeon, concomitant procedures, body mass index (BMI), age, tibial and talus implant sizes, total procedure time and total inflated tourniquet time. …”
Get full text

Comparison of Childbirth Experience and Related Factors in Primiparous Women With Normal Vaginal Delivery and Cesarean Section From Northern Iran by Fatemeh Afshar, Sedigheh Pakseresht, Fatemeh Jafarzadeh-Kenarsari, Saman Maroufizadeh

“…In multivariate analyses, the multiple linear regression analysis was used to determine factors associated with the total CEQ score. …”
Get full text

Priority-Setting for Novel Drug Regimens to Treat Tuberculosis: An Epidemiologic Model. by Emily A Kendall, Sourya Shrestha, Ted Cohen, Eric Nuermberger, Kelly E Dooley, Lice Gonzalez-Angulo, Gavin J Churchyard, Payam Nahid, Michael L Rich, Cathy Bansbach, Thomas Forissier, Christian Lienhardt, David W Dowdy

“…<h4>Methods and findings</h4>We developed a dynamic transmission model of multi-strain TB epidemics in hypothetical populations reflective of the epidemiological situations in India (primary analysis), South Africa, the Philippines, and Brazil. …”
Get full text

Mean nutrient adequacy ratio and associated factors of complementary foods among children aged 6–23 months in Northeast Ethiopia by Abdulkerim Kassaw, Tefera Chane Mekonnen, Erkihun Tadesse Amsalu, Eyob Tilahun ABeje, Chala Daba, Yawkal Tsega, Abel Endawkie

“…The study employed a systematic sampling technique to select 255 children. The data were collected using a 24-h dietary recall method. …”
Get full text

Effect of Dy³⁺ Ions on Structural, Thermal and Spectroscopic Properties of L-Threonine Crystals: A Visible Light-Emitting Material by João G. de Oliveira Neto, Otávio C. da Silva Neto, Jéssica A. O. Rodrigues, Jailton R. Viana, Alysson Steimacher, Franciana Pedrochi, Francisco F. de Sousa, Adenilson O. dos Santos

“…Thermogravimetric and differential thermal analysis experiments showed that L-thr containing Dy³⁺ ions are thermally stable up to 214 °C. …”
Get full text

Multi-branch horizontal well hole docking pressure control extraction technology for close distance coal seam group by Liang CHEN, Zhiheng CHENG, Xin LUO, Hongyang YU, Zherui ZHANG, Peng WANG, Xiangdong WANG

“…Taking Shaqu well field in Lyuliang city, Shanxi province as an example, through theoretical analysis and data statistics, the geological structure of coalbed methane accumulation in the well field, the influence of hydrodynamic conditions, coalbed methane reservoir characteristics and gas-bearing distribution are obtained. …”
Get full text

Translation, Adaptation, and Validation of a Traditional Chinese Version of the Family Caregiver Medication Administration Hassle Scale by Ku TL, Wu SY, Chie WC, Huang YM

“…Qualitative data from interviews were analyzed using content analysis to provide triangulated evidence of scale adaptability.Results: The FCMAHS-TC demonstrated strong internal consistency (Cronbach’s alpha = 0.94) and test-retest reliability (ICC = 0.78). …”
Get full text

Identification of subcellular localization of Arabidopsis AGO2 by ZHAO Li, XIA Wenqiang, CAI Xinzhong

“…Results of detection of green fluorescence signal by confocal laser-scanning microscope showed that AtAGO2 was localized in cytoplasm, plasma membrane and nucleus. Comparative analysis revealed that treatment with 0.2 mmol/L JA, but not 0.38 mmol/L BTH, rendered AtAGO2 was distributed discontinuously in plasma membrane and gathered as bright “granules” in and around plasma membrane.Data in this study revealed that Arabidopsis AGOs were not secretory proteins; AtAGO1, AtAGO3, AtAGO4 and AtAGO9 might be localized in cell nucleus, while AtAGO2 was localized in cytoplasm, plasma membrane and nucleus. …”
Get full text

Otoritas Kufah Asy-Sya‘bī dan Konstruksi Sanad: Kritik terhadap Pendekatan Joseph Schacht dalam Studi Hadis Tabi‘in by Fahmi Riady, Abdul Karim

“…The analysis reveals that Schacht’s claims are heavily influenced by his theoretical framework regarding the early development of Islamic law, including the concept of the common link as an indicator of fabricated chains of transmission (sanad). …”
Get full text

Optical Properties of Near-Surface Cloud Layers and Their Interactions with Aerosol Layers: A Case Study of Australia Based on CALIPSO by Miao Zhang, Yating Zhang, Yingfei Wang, Jiwen Liang, Zilu Yue, Wenkai Song, Ge Han

“…This study utilized Cloud–Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) satellite level-2 data with high-confidence cloud–aerosol discrimination (|CAD| > 70) to investigate the optical properties, vertical distributions, seasonal variations, and aerosol interactions of near-surface cloud layers (cloud base height < 2.5 km) over Australia from 2006 to 2021. …”
Get full text

Pretreatment CT-Based Machine Learning Radiomics Model Predicts Response in Inoperable Stage III NSCLC Treated with Concurrent Radiochemotherapy Plus PD-1 Inhibitors by Ya Li Bachelor, Min Zhang Bachelor, Yong Hu MM, Bo Du Bachelor, Youlong Mo Bachelor, Tianchu He MM, Mingdan Zhao Bachelor, Benlan Li Bachelor, Ji Xia Bachelor, Zhongjun Huang Bachelor, Fangyang Lu MD, Zhen Huang Bachelor, Bing Lu MD, Jie Peng MD

“…Objective To develop and validate a CT-based radiomics model for predicting sequential immunotherapy response after concurrent radiochemotherapy (CCRT) in patients with unresectable stage III non-small cell lung cancer (NSCLC). …”
Get full text

Environmentally safe sorbent from ash-and-slag waste of heat power engineering by S. A. Bushumov, T. G. Korotkova

“…In the case of sorption of oil sludge by calcined and modified sorbents, the residual oil products were insignificant. A comparative analysis of data on the effectiveness of the developed sorbent and currently available analogues based on sludge and slag is presented.Conclusions. …”
Get full text