Evaluating associations between patient-to-nurse ratios and mortality, process of care events and vital sign documentation on paediatric wards: a secondary analysis of data from th... by Orsola Gawronski, Corrado Cecchetti, Emanuela Tiozzo, Marta Luisa Ciofi degli Atti, Massimiliano Raponi, Karen Dryden-Palmer, Christopher S Parshuram, George Tomlinson, Immacolata Dall'Oglio, Leah Szadkowski, Ari Robin Joffe

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Time-lapse imaging systems for embryo incubation and assessment to improve reproductive outcomes in women undergoing in vitro fertilisation: study protocol for an individual partic... by Hannah Park, Cornelis B Lambalk, Madelon van Wely, Shakila Thangaratinam, Laura Del Campo, Peter Kovacs, Javier Zamora, Khalid Saeed Khan, Carlijn G Vergouw, Patricia Fauque, Priya Bhide, David Yiu Leung Chan, Aisling Ahlström, Dorit Kieslinger, Kersti Lundin, Semra Kahraman

“…This may be attributed to heterogeneity in participant populations and/or variations in the use of TLI, as highlighted in the aggregate meta-analyses.Methods and analysis Our research proposal for evidence synthesis using individual participant data meta-analysis will provide greater power than aggregate meta-analysis to detect differential treatment effects for effectiveness (live birth, clinical pregnancy) and safety (pregnancy loss, multiple births, congenital malformations) outcomes across three comparisons (overall effect, undisturbed culture and morphokinetic parameters). …”
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Novel Hemorrhagic Risk Score in Elderly Patients with Coronary Artery Disease and Gastrointestinal Malignant Tumor Comorbidity: A 10-year Clinical Inpatient Data Analysis from 2 Me... by Nandi Bao, Wanling Wang, Huitao Wu, Yabin Wang, Hebin Che, Wenwen Meng, Jiaxin Miao, Dong Han, Fan Yin, Tianyu Xu, Xiaoxia Fu.

“…This study aimed to establish an individualized bleeding risk assessment system based on the analysis of 10-year inpatient clinical big data. Methods:. …”
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Requirement Analysis for Data-Driven Electroencephalography Seizure Monitoring Software to Enhance Quality and Decision Making in Digital Care Pathways for Epilepsy: A Feasibility... by Pantea Keikhosrokiani, Johanna Annunen, Jonna Komulainen-Ebrahim, Jukka Kortelainen, Mika Kallio, Päivi Vieira, Minna Isomursu, Johanna Uusimaa

“…These guidelines encompass system requirements, data collection and analysis, and user training, offering a comprehensive road map for the effective implementation of the software. …”
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Remote data collection speech analysis and prediction of the identification of Alzheimer’s disease biomarkers in people at risk for Alzheimer’s disease dementia: the Speech on the... by Craig W Ritchie, Saturnino Luz, Sarah Gregory, John Harrison, Alexandra König, Nicklas Linz, Kai Langel, Hannah Pullen

“…The outcome of this analysis will inform the development of an algorithm for prediction of AD risk based on speech features.Ethics and dissemination This study has been approved by the Edinburgh Medical School Research Ethics Committee (REC reference 20-EMREC-007). …”
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Data-Independent Acquisition-Based Quantitative Proteomics Analysis of Fertile Red Eggs and Spermatozoa in Hermatypic Coral <i>Galaxea fascicularis</i>: Revealing Key Proteins Rela... by Yinyin Zhou, Jingzhao Ke, Lingyu Zheng, Shaoyang Mo, Xiangbo Liu, He Zhao, Wentao Zhu, Xiubao Li

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Lixisenatide is effective and safe as add-on treatment to basal insulin in Asian individuals with type 2 diabetes and different body mass indices: a pooled analysis of data from th... by Xia Zhang, Ran Meng, Dalong Zhu, Weimin Wang, Guangyu Wu, Minlu Zhang, Wenhuan Feng, Huiqiu Yin

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Benefits and harms of perioperative high fraction inspired oxygen for surgical site infection prevention: a protocol for a systematic review and meta-analysis of individual patient... by Paul Myles, Markus W Hollmann, Janet Martin, Andrew Forbes, Benedetta Allegranzi, Kate Leslie, Robert Greif, Matthew TV Chan, Christian S Meyhoff, Marcel GW Dijkgraaf, Stijn W de Jonge, Carlos Ferrando, Kane Pryor, Andrea Kurz, Daniel I Sessler, Pascal Thibon, Marja Boermeester, Rick H Hulskes, Maedeh Zokaei Nikoo, Robert P Weenink, Ozan Akca, F Javier Belda, Gabriel M Gurman, Christina M Scifres, David S McKenna, Jannicke Mellin-Olsen

“…The purpose of this individual participant data meta-analysis is to assess the described benefits and harms of intraoperative high FiO2compared with regular (0.21–0.40) FiO2 and its potential effect modifiers.Methods and analysis Two reviewers will search medical databases and online trial registries, including MEDLINE, Embase, CENTRAL, CINAHL, ClinicalTrials.gov and WHO regional databases, for randomised and quasi-RCT comparing the effect of intraoperative high FiO2 (0.60–1.00) to regular FiO2 (0.21–0.40) on SSI within 90 days after surgery in adult patients. …”
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Impact of vaccination status on the clinical course and outcomes of acute COVID-19 period: data from the international registry "Dynamics Analysis of Comorbidities in SARS-CoV-2 Su... by G. P. Arutyunov, E. I. Tarlovskaya, A. G. Arutyunov, D. S. Polyakov, Yu. M. Lopatin, A. I. Chesnikova, L. A. Balykova, A. R. Vaisberg, A. S. Galyavich, N. Yu. Grigorieva, V. B. Grinevich, I. V. Gubareva, I. V. Demko, A. V. Zharkov, D. N. Zaitsev, Z. F. Kim, V. L. Korobka, N. V. Lareva, E. V. Makarova, S. V. Malchikova, S. V. Nedogoda, A. G. Obrezan, A. G. Hovakimyan, S. V. Pereverzev, M. M. Petrova, I. G. Pochinka, K. V. Protasov, D. N. Protsenko, A. P. Rebrov, O. A. Rubanenko, D. Yu. Ruzanov, A. V. Svarovskaya, N. M. Selezneva, E. A. Smirnova, A. B. Sygraliev, O. V. Khlynova, I. I. Shaposhnik, D. A. Sh'ukarev, A. K. Abdrakhmanova, T. P. Abdualimov, A. V. Agafonov, V. G. Hakobjanyan, L. N. Allahkuliyeva, A. V. Aparkina, O. Yu. Barysheva, T. I. Batluk, A. S. Batchayeva, R. A. Bashkinov, Ya. A. Belenikina, I. V. Bikushova, A. Zh. Botabekova, S. N. Botova, V. O. Bochkareva, G. A. Bykova, K. R. Vagapova, V. V. Vasilev, N. N. Vezikova, K. S. Viktorov, V. V. Genkel, A. I. Girivenko, O. P. Girich, E. S. Godunko, N. V. Gordeeva, E. D. Gordeychuk, E. I. Gorshenina, E. V. Grigorieva, E. Yu. Gubareva, I. L. Davydkin, A. K. Duisenova, D. S. Evdokimov, L. S. Evdokimova, A. E. Zheldybayeva, Yu. D. Zimina, I. A. Zolotovskaya, E. Yu. Ivanchenko, A. K. Izhanova, M. V. Kazakovtseva, S. F. Ghazaryan, M. K. Kaidarbek, I. A. Karetnikov, N. A. Karoli, D. S. Kaskaeva, E. S. Kim, E. V. Kozlov, V. Yo. Koliev, M. I. Koliadich, D. Yu. Konstantinov, E. A. Konstantinova, A. K. Konussova, A. V. Korobka, A. A. Korolev, N. B. Kosacheva, Yu. A. Kravchuk, A. Yu. Kraposhina, T. V. Kryukova, A. S. Kuznetsova, K. V. Kuzmichev, O. Yu. Kuchiyash, Yu. I. Lebedeva, T. M. Levina, K. V. Levchenko, Artem Vyacheslavovich Levshin, A. A. Ledyaeva, T. V. Lisun, N. A. Lyubavina, M. V. Lyubimov, N. A. Magdeyeva, O. A. Mazhara, V. I. Maiseenko, A. S. Makarova, V. D. Ma-Van-de, A. A. Matuzkova, O. V. Mashkunova, E. S. Melnikov, N. B. Moiseenko, N. V. Mukha, N. M. Nikitina, D. V. Oblavatckii, I. A. Obukhova, O. V. Obukhova, Sh. O. Ospanova, S. S. Plastinina, V. A. Pogrebetskaya, D. V. Polyakov, E. V. Ponomarenko, L. L. Popova, M. V. Popov, A. O. Rubanenko, O. A. Rusinova, F. E. Rustamova, A. M. Sadykova, P. V. Seliverstov, S. Serikbolkyzy, D. A. Sinkevich, I. A. Solovieva, E. A. Stepina, E. I. Suchkova, D. S. Tokmin, A. A. Tolmacheva, D. A. Trofimov, M. A. Trubnikova, A. A. Tulichev, I. A. Tuchin, S. T. Ualieva, N. D. Ulanova, O. V. Fedorishina, A. I. Khaltskaya, S. H. Hamidov, L. N. Khokhlova, L. N. Khusainova, V. V. Tsoma, T. I. Chudinovskikh, А. O. Shabelsky, A. O. Shvidko, E. A. Shishkina, S. S. Shostak-Krickii, S. Yu. Sherbakov, M. I. Yarigina

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Early-life growth and emotional, behavior and cognitive outcomes in childhood and adolescence in the EU child cohort network: individual participant data meta-analysis of over 109,... by Romy Gonçalves, Sophia Blaauwendraad, Demetris Avraam, Andrea Beneíto, Marie-Aline Charles, Ahmed Elhakeem, Joaquin Escribano, Louise Etienne, Gonzalo García-Baquero Moneo, Ana Gonçalves Soares, Jasmin de Groot, Veit Grote, Dariusz Gruszfeld, Kathrin Guerlich, Monica Guxens, Barbara Heude, Berthold Koletzko, Aitana Lertxundi, Manuel Lozano, Hanan El Marroun, Rosie McEachan, Angela Pinot de Moira, Gillian Santorelli, Katrine Strandberg-Larsen, Muriel Tafflet, Chloe Vainqueur, Elvira Verduci, Martine Vrijheid, Marieke Welten, John Wright, Tiffany C. Yang, Romy Gaillard, Vincent W.V. Jaddoe

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Transcriptomic insights into grain size development in naked barley (Hordeum vulgare L. var. nudum Hook. f): based on weighted gene co-expression network analysis by Yan Wang, Jiahao Zhou, Mingqi Yang, Youhua Yao, Yongmei Cui, Xin Li, Baojun Ding, Xiaohua Yao, Kunlun Wu

“…By integrating longitudinal three-dimensional phenotypic data with temporal expression profiles and applying weighted gene co-expression network analysis (WGCNA), we successfully identified gene modules that co-vary with morphological expansion. …”
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Global Analysis of microRNA-like RNAs Reveals Differential Regulation of Pathogenicity and Development in <i>Fusarium oxysporum HS2</i> Causing Apple Replant Disease by Ruxin Zhao, Xiangmin Suo, Xianglong Meng, Yanan Wang, Pengbo Dai, Tongle Hu, Keqiang Cao, Shutong Wang, Bo Li

“…Notably, the highest number of differentially or specifically expressed milRNAs (DEmilRNAs/SEmilRNAs) was found during the spore stage, with <i>FoHS2</i>-milR19 targeting genes encoding histone acetyltransferases, methyltransferases, and cell wall-degrading enzymes (CWDEs), which are crucial for growth, development, and pathogenicity. We validated the reliability of our sRNA-seq data and the expression of target genes using stem-loop RT-PCR and qRT-PCR. …”
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Liquid Chromatography/Tandem Mass Spectrometry-Based Simultaneous Analysis of 32 Bile Acids in Plasma and Conventional Biomarker-Integrated Diagnostic Screening Model Development f... by Minami Yamauchi, Masamitsu Maekawa, Toshihiro Sato, Yu Sato, Masaki Kumondai, Mio Tsuruoka, Jun Inoue, Atsushi Masamune, Nariyasu Mano

“…After determining the concentrations of 32 bile acids, statistical analysis and diagnostic screening model development were performed. …”
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Driving inclusive growth through financial systems and technology adoption: a global analysis of synergistic pathways using structural equation modeling by Ummar Faruk Saeed, Godfred Etse Klugah

“…This study investigates the mediating role of ICT access in the relationship between FD and inclusive growth (IG), using cross-sectional data from 132 countries for the year 2022. Grounded in Endogenous Growth Theory and the Resource-Based View, the analysis employs Partial Least Squares Structural Equation Modeling (PLS-SEM) to test three key hypotheses. …”
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Development and validation of a machine learning-based predictive model for compassion fatigue in Chinese nursing interns: a cross-sectional study utilizing latent profile analysis by Lijuan Yi, Ting Shuai, Jingjing Zhou, Liang Cheng, Maria F. Jiménez-Herrera, Xu Tian

“…Results A three-profile model best fits the data, identifying low (55.73%), moderate (32.17%), and severe (12.10%) profiles for compassion fatigue. …”
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Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep by Zhenzhen Gu, Zhenzhen Gu, WeiWei Duan, WeiWei Duan, Chenxi Liu, Chenxi Liu, Chenxi Liu, Wenrong Li, Wenrong Li, Wenrong Li, Bin Han, Bin Han, Bin Han, Mingjun Liu, Mingjun Liu, Mingjun Liu, Mingjun Liu

“…The functions of key miRNAs and target genes were determined by qRT-PCR, Western blot, dual-luciferase reporter gene assay, and Immunofluorescence staining.ResultsA total of 284 differentially expressed miRNAs (DE-miRNAs) were screened by comparing the transcriptome data across all 11 periods. DE-miRNAs were divided into two developmental stages (stage A and stage B) based on heat map clustering analysis. …”
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Disentangling the Switching Behavior in Functional Connectivity Dynamics in Autism Spectrum Disorder: Insights from Developmental Cohort Analysis and Molecular‐Cellular Association... by Wei Li, Xia Qiu, Jin Chen, Kexuan Chen, Meiling Chen, Yinyan Wang, Wenjie Sun, Jing Su, Yongchang Chen, Xiaobao Liu, Congying Chu, Jiaojian Wang

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Analysis of Differences Between Groups of Locomotive Crew Drivers With Different Degrees of Ability to Arbitrarily Regulate Their Functional State by N. V. Shcherbina

“…For the analysis, we used the data of psychophysiological examination using the UPDK-MK complex for professional psychophysiological examination and selection of railway workers (Neurokom, Russia) and data obtained by the method of functional biocontrol with biofeedback (NeuroDog, Neurokom, Russia). …”
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Estimating Spatiotemporal Dynamics of Carbon Storage in <i>Roinia pseudoacacia</i> Plantations in the Caijiachuan Watershed Using Sample Plots and Uncrewed Aerial Vehicle-Borne Las... by Yawei Hu, Ruoxiu Sun, Miaomiao He, Jiongchang Zhao, Yang Li, Shengze Huang, Jianjun Zhang

“…The findings provide valuable data support for density management and high-quality development of <i>R. pseudoacacia</i> plantations in the Caijiachuan watershed and present an efficient approach for precise forest carbon sink accounting.…”
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Emo-SL Framework: Emoji Sentiment Lexicon Using Text-Based Features and Machine Learning for Sentiment Analysis by Manar Alfreihat, Omar Saad Almousa, Yahya Tashtoush, Anas AlSobeh, Khalid Mansour, Hazem Migdady

“…Recently, given the rise of types of social media networks, the analysis of sentiment and opinions in textual data has gained significant importance. …”
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