Modified electroconvulsive therapy for perinatal depression: scoping review by William V. Bobo, William V. Bobo, William V. Bobo, Owen Moore, Catherine B. Hurley, Robyn Rosasco, Emily E. Sharpe, Alyssa M. Larish, Katherine M. Moore, Hannah K. Betcher

“…BackgroundModified electroconvulsive therapy (mECT), the administration of ECT under general anesthesia with muscular relaxation, is indicated for perinatal depression complicated by high severity, psychosis, catatonia, or resistance to conventional therapeutics; however, knowledge gaps remain regarding its effectiveness and safety in depressed patients and its fetal/neonatal risk profile.Materials and methodsWe conducted a scoping review of the literature describing the effectiveness and safety (maternal, fetal, and neonatal) of mECT for perinatal depression. …”
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Hymecromone Administration in Real Clinical Practice: Results of the Prospective Multicentre Observational Study in the Republic of Kazakhstan by A. V. Nersesov, D. A. Kaybullaeva, V. S. Rakhmetova, I. A. Lozinskaya, A. K. Kurmangalieva, V. S. Ayupova, A. B. Orazbaeva, A. K. Kanabaeva, Yu. O. Shulpekova

“…The objectives of the study included collection of clinical characteristics of patients, evaluation of Odeston effects in treatment of biliary pain and changes in the gallbladder emptying, evaluation of compliance to therapy, and treatment effect satisfaction.Materials and methods. …”
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Causal association of modifiable factors with cardiometabolic multimorbidity: an exposome-wide Mendelian randomization investigation by Dun Li, Jing Lin, Hongxi Yang, Lihui Zhou, Yujian Li, Zhe Xu, Li Sun, Xinyu Zhang, Weili Xu, Yaogang Wang

“…Updated large-scale genome-wide association study (GWAS) data based on systematic collection from GWAS Catalog were applied. …”
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Metformin blocks BIK1-mediated CPK28 phosphorylation and enhances plant immunity by Yazhou Bao, Qian Zhang, Hai Zhu, Yong Pei, Yaning Zhao, Yixin Li, Peiyun Ji, Dandan Du, Hao Peng, Guangyuan Xu, Xiaodan Wang, Zhiyuan Yin, Gan Ai, Xiangxiu Liang, Daolong Dou

“…Moreover, MET enhanced disease resistance in tomato, pepper, and soybean plants. Conclusion: Collectively, our data suggest that MET enhances plant immunity by blocking BIK1-mediated CPK28 phosphorylation.…”
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Environmental impact, cost, and acceptability of a laboratory sustainability certification program for biomedical research in an academic medical center by Michael Padget, Pernilla Sörme, Michael Spezia, Susan A. Slaugenhaupt, James McKowen, Emily Kirchner, Natalie Ameral, Surya A. Reis, Damien Slater, Stephen J. Haggarty, Benjamin P. Kleinstiver, Erin C. Dunn, Regina Larocque, Christiano R.R. Alves, Max Stern, Alida Pelli, Ann-Christine Duhaime

“…This study sought to assess the feasibility, acceptability, and impact of a formal laboratory sustainability certification process within a large AMC research institute. Methods: Five labs with diverse research profiles participated in an external certification process consisting of the collection of baseline questionnaire data, a customized intervention plan to reduce environmental impacts, and a follow-up questionnaire to assess changes made and their effects. …”
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Hope and challenges in the diagnosis and treatment of Wilms tumor: a single-center retrospective study in China by Kongkong Cui, Kongkong Cui, Peng Hong, Peng Hong, Jie Lin, Jie Lin, Zaihong Hu, Zaihong Hu, Zhiqiang Gao, Zhiqiang Gao, XiaoMao Tian, XiaoMao Tian, Tao Lin, Tao Lin, Qinlin Shi, Qinlin Shi, Guanghui Wei, Guanghui Wei

“…It involved the collection of sociodemographic and clinical details, including data on patients who abandoned treatment. …”
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Exploring voluntary sector specialist services for victim-survivors of sexual violence in England: the PROSPER co-production study by Caroline Bradbury-Jones, Sarah Damery, Kirsten Fruin, Clare Gunby, Jenny Harlock, Lucy Hebberts, Louise Isham, Anne-Marie Jones, Fay Maxted, Amelia Mighty, Priti Parmar, Laura Patterson, Jason Schaub, Fee Scott, Harriet Smailes, Debs Smith, Julie Taylor

“…Limitations The COVID-19 pandemic meant that we were unable to use the proposed methods of data collection for the qualitative components. …”
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Systematic metabolic characterization of mental disorders reveals age‐related metabolic disturbances as potential risk factors for depression in older adults by Yu Liu, Wanyu Zhao, Ying Lu, Yunli Zhao, Yan Zhang, Miao Dai, Shan Hai, Ning Ge, Shuting Zhang, Mingjin Huang, Xiaohui Liu, Shuangqing Li, Jirong Yue, Peng Lei, Biao Dong, Lunzhi Dai, Birong Dong

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Genetic depletion of adipose-derived Isthmin-1 causes hepatic steatosis by Saranya C. Reghupaty, Laetitia Coassolo, Meng Zhao, Ramya Lakshmi Narasimhan, Aayan Patel, Jameel Lone, Ewa Bielczyk-Maczynska, Niels B. Danneskiold-Samsoee, Taylor Brown, Zewen Jiang, Veronica L. Li, Katrin J. Svensson

“…These results provide in vivo genetic support for the role of Ism1 as a regulator of the adipose–hepatic axis. Conclusions: Collectively, these data demonstrate that loss of adipose-derived Ism1 disrupts lipid homeostasis and accelerates the development of hepatic steatosis. …”
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A systematic review of Leptospira in water and soil environments. by Emilie Bierque, Roman Thibeaux, Dominique Girault, Marie-Estelle Soupé-Gilbert, Cyrille Goarant

“…However, little is known on their capacity to survive in a soil and freshwater environment.<h4>Methods</h4>We conducted a systematic review on Leptospira and leptospirosis in the environment in order to collect current knowledge on the lifestyle of Leptospira in soil and water. …”
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Characteristics and Risk Assessment of Group Landslide-Debris Flow Disaster Chain in the Hilly Mountains of South China: A Case Study of the Magui River Basin in Gaozhou, Western G... by Shen Qiuhua, Wang Jun, Li Hao, Gong Qinghua, Li Nianqin, Li Jingfu, Yuan Shaoxiong, Liu Bowen

“…It is mainly distributed in the small watersheds of Shanxin Village, Houyuan Village South, Yadong Village South, and Zhoukeng Village in the northeast; Daxi Village in the west; Hemudong Village in the central region; and Longkeng Village in the south. 3) The evaluation results of this study were verified using actual investigation data, which showed high consistency with field survey results, thereby confirming the credibility of the method employed in this study. …”
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The burden of disease in seronegative myasthenia gravis: a patient-centered perspective by Sophie Lehnerer, Sophie Lehnerer, Sophie Lehnerer, Sophie Lehnerer, Regina Stegherr, Ulrike Grittner, Ulrike Grittner, Maike Stein, Maike Stein, Maike Stein, Maike Stein, Lea Gerischer, Lea Gerischer, Frauke Stascheit, Frauke Stascheit, Meret Herdick, Meret Herdick, Paolo Doksani, Paolo Doksani, Andreas Meisel, Andreas Meisel, Andreas Meisel, Sarah Hoffmann, Sarah Hoffmann

“…This study examines the burden of disease, treatment response, and quality of life of snMG patients in comparison to AChR-ab+ MG patients and healthy controls.MethodsA questionnaire-based survey was conducted collecting sociodemographic and clinical data including antibody status, therapy, treatment response, and self-rated disease severity along with standardized assessments such as MG-ADL (activities of daily living) and the Short Form Health (SF-36, generic Health-Related Quality of Life, HRQoL). …”
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Pregnancy urinary phenol biomarker concentrations in relation to serum levels of inflammatory cytokines: Results from the EARTH study by Xinxiu Liang, Sarah Grill, Xilin Shen, Paige L. Williams, Tamarra James-Todd, Jennifer B. Ford, Kathryn M. Rexrode, Antonia M. Calafat, Jorge E. Chavarro, Russ Hauser, Lidia Mínguez-Alarcón

“…Objective: To evaluate associations between urinary phenol biomarkers and serum inflammatory cytokines across pregnancy, and to examine whether associations vary by trimesters. Methods: We included 175 pregnant women from the Massachusetts General Hospital Fertility Center and participating in the Environment and Reproductive Health (EARTH) Study (2005–2017), with available data on urinary concentrations of eight phenol biomarkers and serum inflammatory biomarkers, high-sensitivity C-reactive protein (hsCRP) and interleukin-6 (IL-6). …”
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Gut health-promoting foods intake in Argentine adults: The impact of knowledge, socio-demographic factors, and clinical-nutritional health by Georgina Noel Marchiori, Mayra Ainelén Loyola, Clara Marián Levy Sánchez, María Daniela Defagó, María Georgina Oberto

“…An online questionnaire was used to collect socio-demographic, clinical-nutrition and dietary data, as well as information about population's knowledge. …”
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Bringing a Systems Approach to Living Donor Kidney Transplantation by Anna Horton, Katya Loban, Peter Nugus, Marie-Chantal Fortin, Lakshman Gunaratnam, Greg Knoll, Istvan Mucsi, Prosanto Chaudhury, David Landsberg, Michel R. Pâquet, Marcelo Cantarovich, Shaifali Sandal

“…Data collection entailed semistructured interviews (n = 91), document review (n = 97) and focus groups (n = 5 with 40 participants), analyzed using inductive thematic analysis. …”
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Protocol of the China ST-segment elevation myocardial infarction (STEMI) Care Project (CSCAP): a 10-year project to improve quality of care by building up a regional STEMI care net... by Yong Huo, Yan Zhang, Bo Yu, Ming Wu, Yaling Han, Jianan Wang, Lixia Yang, Zheng Wan, Zheng Zhang, Yuguo Chen, Xianghua Fu, Bao Li, Jiyan Chen, Yitong Ma, Xingsheng Zhao, Yundai Chen, Hongbing Yan, Dingcheng Xiang, Weiyi Fang, Sameer Mehta, Christoph K Naber, Junbo Ge

“…Phase 1 (CSCAP-1) focuses on the in-hospital process optimisation of primary percutaneous coronary intervention (PPCI) hospitals, phase 2 (CSCAP-2) focuses on the PPCI hospital-based regional STEMI care network construction together with emergency medical services and adjacent non-PPCI hospitals, while phase 3 (CSCAP-3) focuses on the whole-city STEMI care network construction by promoting chest pain centre accreditation. Systematic data collection, key performance index assessment and subsequent improvement are implemented throughout the project to continuously improve the quality of STEMI care.Ethics and dissemination The study has been reviewed and approved by the Ethics Committee of Peking University First Hospital. …”
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Clinical trial landscape for pneumonia: Evolving agents against bacterial pathogens by Du Feng, Huixin Jiang, Hao Deng, Gengda Huang, Yue Zhu, Rong Xiao, Gengjia Chen, Chengzhi Zhou

“…Interventional clinical trials investigating therapeutic agents for bacterial pneumonia were included. Data collection encompassed trial status, primary drugs, mechanisms of action, patient demographics, and completion dates. …”
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Describing the initial results of a pragmatic, cluster randomized clinical trial to examine the impact of a multifaceted digital intervention for the prevention of type 2 diabetes... by Sofía Mira-Martínez, Sofía Mira-Martínez, Sofía Mira-Martínez, Rocío Zamanillo-Campos, Rocío Zamanillo-Campos, Rocío Zamanillo-Campos, Narges Malih, Narges Malih, Narges Malih, Maria Antonia Fiol-deRoque, Maria Antonia Fiol-deRoque, Maria Antonia Fiol-deRoque, Maria Antonia Fiol-deRoque, Escarlata Angullo-Martínez, Rafael Jimenez, Rafael Jimenez, Maria Jesús Serrano-Ripoll, Maria Jesús Serrano-Ripoll, Maria Jesús Serrano-Ripoll, Maria Jesús Serrano-Ripoll, José Iván Oña, Aina M Galmes-Panades, Aina M Galmes-Panades, Aina M Galmes-Panades, Rocío Gómez-Juanes, Rocío Gómez-Juanes, Rocío Gómez-Juanes, Rocío Gómez-Juanes, Jadwiga Konieczna, Jadwiga Konieczna, Jerónima Miralles, Jerónima Miralles, Dora Romaguera, Dora Romaguera, María Clara Vidal-Thomasa, María Clara Vidal-Thomasa, María Clara Vidal-Thomasa, Joan Llobera-Canaves, Joan Llobera-Canaves, Joan Llobera-Canaves, Joan Llobera-Canaves, Mauro García-Toro, Mauro García-Toro, Mauro García-Toro, Mauro García-Toro, Elena Gervilla-García, Elena Gervilla-García, Catalina Vicens, Catalina Vicens, Catalina Vicens, Oana Bulilete, Oana Bulilete, Oana Bulilete, Oana Bulilete, Juan José Montaño, Juan José Montaño, Margalida Gili, Margalida Gili, Margalida Gili, Margalida Gili, Miquel Roca, Miquel Roca, Miquel Roca, Antoni Colom, Antoni Colom, Ignacio Ricci-Cabello, Ignacio Ricci-Cabello, Ignacio Ricci-Cabello, Ignacio Ricci-Cabello

“…We combined multiple virtual strategies (SMS, phone calls, promotional videos) to recruit healthcare professionals and their patients. We collected baseline data from patients (sociodemographic, behavioral and clinical) and healthcare professionals (sociodemographic and professional experience).ResultsThe intervention consisted in delivering personalized short text messages supporting lifestyle behavior changes to people at risk of type 2 diabetes; and online training to their primary healthcare professionals. …”
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Accelerated symptom improvement in Parkinson’s disease via remote internet-based optimization of deep brain stimulation therapy: a randomized controlled multicenter trial by Alireza Gharabaghi, Sergiu Groppa, Marta Navas-Garcia, Alfons Schnitzler, Laura Muñoz-Delgado, Vicky L. Marshall, Jessica Karl, Lin Zhang, Ramiro Alvarez, Mary S. Feldman, Michael J. Soileau, Lan Luo, S. Elizabeth Zauber, Benjamin L. Walter, Chengyuan Wu, Hong Lei, Damian M. Herz, Ming-Hua Chung, Yagna Pathak, Bram Blomme, Binith Cheeran, Corneliu Luca, Daniel Weiss

“…Patients, caregivers, and outcome assessors were not blinded to group assignment. Most of the data collection took place in the patient’s home environment. …”
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Epidemiological and molecular analysis of anthrax cases of the Zhambyl region Kazakhstan in 2023 by Uinkul Izbanova, Altyn Rysbekova, Zauresh Zhumadilova, Galina Kovaleva, Gulnara Tokmurziyeva, Bek Abdeliyev, Duman Yessimseit, Elmira Begimbayeva, Saule Umarova, Anar Zarkymanova, Meruert Sabitova, Aisazhan Yussupov, Alexandr Shevtsov, Svetlana Isaeva, Nur Tukhanova, Nur Tukhanova

“…Data collection included patient demographics, exposure circumstances, clinical manifestations, and laboratory diagnostics. …”
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