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50861
Neurotoxic and Neuroprotective Effects of Psychedelics in a Human Neuroblastoma Cell Model
Published 2025-06-01“…They have recently gained attention also for their potential therapeutic applications in treating neurological and psychiatric disorders [1]. …”
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50862
Preparation, and ex vivo and in vivo Characterization of Favipiravir-Loaded Aspasomes and Niosomes for Nose-to-Brain Administration
Published 2025-05-01“…The in vitro–in vivo correlation study showed good correlation between the in vitro and the in vivo pharmacokinetic data.Conclusion: FAV-ASP8 for nose-to-brain delivery system could be a promising formulation to improve FAV bioavailability compared to FAV-NIO9. …”
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50863
Current state of methods for control the safety and potency of diphtheria toxoid and tetanus toxoid in combined vaccines
Published 2022-07-01“…In case of death purified DT is not applicable. TT specific safety control is also carried out on guinea pigs. …”
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50864
Progress in silicon-based reconfigurable and programmable all-optical signal processing chips
Published 2025-05-01“…In this paper, we review the recent progress in the project granted to develop silicon-based reconfigurable AOSP chips, which aims to combine the merits of AOSP and silicon photonics to solve the unsustainable cost and energy challenges in future communication and big data applications. Three key challenges are identified in this project: (1) how to finely manipulate and reconfigure optical fields, (2) how to achieve ultra-low loss integrated silicon waveguides and significant enhancement of nonlinear effects, (3) how to mitigate crosstalk between optical, electrical and thermal components. …”
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50865
Effects of antagonistic network-targeted tDCS on brain co-activation patterns depends on the networks’ electric field: a simultaneous tDCS-fMRI study
Published 2025-08-01“…A total of 143 healthy participants were recruited and assigned to receive central executive network (CEN)-targeted tDCS (C-targeted group), default mode network (DMN)-targeted tDCS (D-targeted group), or sham tDCS (sham group). fMRI data with three sections (pre-stimulation, during-stimulation, post-stimulation) were collected across all subjects. …”
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50866
Development of a core patient-centred outcome set for adults living with obesity: a modified delphi-based international consensusResearch in context
Published 2025-09-01“…Implementation can support the creation of a robust international data resource to guide research, inform clinical practice, and shape policy and guidelines for adult obesity treatment. …”
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50867
The Reliability of a Novel Structured Testing Device for Single-breath Lung Carbon Monoxide Uptake: A Randomized Comparison Crossover Study
Published 2025-05-01“…Clinical trial number Not applicable.…”
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50868
Remote Sensing Video Tracking: Current Status, Challenges, and Future
Published 2025-01-01“…With the rapid advancement of remote sensing technology, the acquisition and processing of remote sensing video data, including high-resolution satellite, hyperspectral, and synthetic aperture radar video, have become key research areas in remote sensing. …”
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50869
Effect of grinding wheel type and cooling method on grinding quality of SiCf/SiC ceramic matrix composites
Published 2025-04-01“…Therefore, in practical applications, the grinding wheels and cooling methods should be reasonably selected based on different processing requirements to improve the processing quality and the efficiency of SiCf/SiC composites. …”
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50870
Photon sensor-based monitoring of spatial variations in canopy FIPAR for crop growth assessment
Published 2025-03-01“…Crop growth monitoring technology holds great potential to enable timely management adjustments, optimize resource use, and support sustainable agriculture practices, achieving efficient intelligent agriculture for data-driven cultivation. Traditional field measurement and monitoring methods are often inefficient and provide limited, outdated information. …”
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50871
A predictive machine-learning model for clinical decision-making in washed microbiota transplantation on ulcerative colitis
Published 2024-12-01“…Background and Aim: Machine learning based on clinical data and treatment protocols for better clinical decision-making is a current research hotspot. …”
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50872
Utilizing brown mushroom stem waste as an eco-friendly alternative to soybean meal in layer chick nutrition
Published 2025-08-01“…At the end of the study, randomly selected birds were slaughtered for blood and organ collection for further analysis. Data analysis was performed using one-way ANOVA in SAS 9.4 software. …”
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50873
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50874
In vitro and in silico investigations of Propolis-derived phytochemicals as potential inhibitors of Plasmodium falciparum
Published 2025-06-01“…Molecular docking and 100-ns molecular dynamic (MD) simulations were performed to evaluate the binding affinity and stability of selected compounds (tectochrysin and galangin) against PfLDH in both holo (Protein Data Bank [PDB] ID: 1LDG) and apo (PDB ID: 2X8L) forms. …”
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50875
Phenotypic Timeline Kinetics, Integrative Networks, and Performance of T- and B-Cell Subsets Associated with Distinct Clinical Outcome of Severe COVID-19 Patients
Published 2024-11-01“…Peripheral blood obtained at distinct time points (baseline/D0; D7; D14-28) was used for ex vivo flow cytometry immunophenotyping. The data demonstrated a decrease at D0 in the frequency of CD3<sup>+</sup> T-cells and CD4<sup>+</sup> T-cells and an increase in B-cells with mixed activation/exhaustion profiles. …”
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50876
The acceptability of blood spot screening and genome sequencing in newborn screening: a systematic review examining evidence and frameworks
Published 2025-03-01“…Qualitative studies were analysed for recurring themes, and a meta-synthesis was carried out to compare and contrast these two types of data. We quality appraised included articles using tools appropriate for their study design. …”
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50877
Estimating canopy nitrogen content by coupling PROSAIL-PRO with a nitrogen allocation model
Published 2024-12-01“…In contrast, physically based methods use the full-range reflectance data and retrieve CNC from coupled leaf and canopy radiative transfer models (such as PROSPECT-PRO + 4SAIL, PROSAIL-PRO). …”
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50878
Speeding up drug susceptibility testing in Mycobacterium tuberculosis using RNA biomarkersResearch in context
Published 2025-03-01“…The performance of TRACeR-TB was compared to the widely used Mycobacteria Growth Indicator Tube [MGIT] pDST by subjecting 238 strains with diverse drug resistance profiles to both methods, and aligning results to genotypic data. Furthermore, we explored TRACeR-TB's potential for evaluating molecules that enhance antibiotic efficacy, and investigated its applicability in macrophage models to assess Mtb's intracellular stress responses to drugs. …”
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50879
Optimal control strategies supported by system dynamics modelling: a study on hookworm disease in China
Published 2025-03-01“…Generalized linear models were constructed from simulation data, accounting for the impact of survey sites. …”
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50880
Life satisfaction around the world: Measurement invariance of the Satisfaction With Life Scale (SWLS) across 65 nations, 40 languages, gender identities, and age groups.
Published 2025-01-01“…Here, we utilised the Body Image in Nature (BINS) dataset-with data collected between 2020 and 2022 -to assess measurement invariance of the SWLS across 65 nations, 40 languages, gender identities, and age groups (N = 56,968). …”
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