Key performance indicators for acute intermittent kidney replacement therapy in critically ill patients: a protocol for a systematic review by Oleksa G Rewa, Sean M Bagshaw, Javier A Neyra, Matthew James, Liza Bialy, Scott Klarenbach, Xiaoming Wang, N Pannu, Fadi Hammal, Dawn Opgenorth, Janice Y Kung, Jeanna Morrissey, Kristin Robertson, Samantha L Bowker, Selvi Sinnadurai, Ashita Tolwani, Michael Heung, Teresa Mottes

“…Finally, KPIs will be appraised for potential operational characteristics, potential to be integrated into electronic medical records, adoptability by stakeholders and affordability, if applicable.Ethics and dissemination Ethics approval is not required as primary data will not be collected. …”
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Hydrogel in musculoskeletal diseases: Unraveling trends, research foci, and future trajectories via bibliometric insights (from 2000 to 2025) by Weibei Sheng, Siyang Cao, Haotian Qin, Peng Liu, Deli Wang, Jian Weng, Hui Zeng, Fei Yu

“…However, despite growing interest in this field, current reviews often lack systematic, data-driven insights into the evolving research landscape. …”
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Much More Than the Malady: The Promise of a Web-Based Digital Platform Incorporating Self-Report for Research and Clinical Care in Mild Cognitive Impairment by Andrew McGarry, MD, Oliver Roesler, PhD, Jackson Liscombe, PhD, Michael Neumann, PhD, Hardik Kothare, PhD, Abhishek Hosamath, MBM, Lakshmi Arbatti, MS, Anusha Badathala, MD, Stephen Ruhmel, BS, MPH, Bryan J. Hansen, PhD, Madeline Quall, BA, Sandrine Istas, MBio, Arthur Wallace, MD, PhD, David Suendermann-Oeft, PhD, Vikram Ramanarayanan, PhD, Ira Shoulson, MD

“…The MCI was associated with 6 times more difficulty with falls (n=6 vs 1). These data support the feasibility and discriminative utility of using remote monitoring technology in combination with participant self-report in an MCI population. …”
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Interplay of PAK1 and CAMKII in Pancreatic Beta Cell Insulin Secretion by Nely Gisela López-Desiderio, Genaro Patiño-López, Citlaltépetl Salinas-Lara, Carlos Sánchez-Garibay, Olga Villamar-Cruz, Alonso Vilches-Flores, José de Jesús Peralta-Romero, Leonel Armas-López, Jazmín García-Machorro, Luis Enrique Arias-Romero, Héctor Iván Saldívar-Cerón

“…Further studies are warranted to explore their mechanistic roles and therapeutic applications in preserving beta-cell function.…”
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Epidemiological trends and burden of metabolic dysfunction-associated steatotic liver disease in the Middle East and North Africa region: a 32-year analysis of health impact by Zahra Sarkoohi, Mohammad-Mahdi Bastan, Mohammad Amin Khajuei Gharaei, Mahsa Iranmanesh, Arya Adinepour, Reyhane Khajezade, Faegheh Bahri, Fatemeh Akhlaghi, Azin Kadkhodamanesh, Hossein Pourghadamyari, Hamid Sharifi, Omid Eslami, Seyed Aria Nejadghaderi

“…Clinical trial number Not applicable.…”
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Investigating the effects of animal-specific δ15N-NH3 values volatilized from livestock waste on regional NH3 source partitioning by Dong Liu, Zhi Quan, Yingying Wang, Kai Huang, Quanping Zhang, Linlin Song, Shaonan Huang, Yanzhi Wang, Zhifeng Xun, Deze Liu, Chang Liu, Yunting Fang, Jianping Sun

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Oxygen vacancy-driven spin-transfer torque across MgO magnetic tunnel junctions by L. M. Kandpal, B. Taudul, E. Monteblanco, A. Kumar, K. Katcko, F. Schleicher, P. Gupta, S. Boukari, W. Weber, V. Da Costa, J. D. Costa, T. Bӧhnert, R. Ferreira, P. Freitas, M. Hehn, M. Alouani, P. K. Muduli, D. Lacour, M. Bowen

“…As MTJs are now downscaled to 2 nm, basic experimental data challenge the accepted understanding of their operation. …”
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Unlocking the African bioeconomy and strengthening biodiversity conservation through genomics and bioinformatics by Ichrak Hayah, Victor Ezebuiro, Samuel Paul Kagame, Josiah Ochieng Kuja, Cecilia Waruhiu, Lucky Tendani Nesengani, Sinebongo Mdyogolo, Annelin Henriehetta Molotsi, Priscilla Abechi, Asmaa Mohamed Abushady, Nabil Amor, Brian Andika, Abdelhamid Barakat, Girish Beedessee, Marietjie Botes, Xavier David, Nzube Ebuzoeme, Zewdu Edea, Achraf El Allali, Owanate Pearl Elekima, Assem Kadry Elsherif, Semir Bechir Suheil Gaouar, Yohannes Gedamu Gebre, Owunari Abraham Georgewill, Lydia Hadjeras, Mohammed Ahmed Hassan, Mohamed Hijri, Isidore Houaga, Justin Eze Ideozu, Matthias Igoh, Mary Paschal Iwundu, Syed Arif Sulthan Jaffer Ali, Atef Jaouani, Ahmed Marwane Kermouni Serradj, Radjaa Khedim, Mariëtte Kilian, Dennis Manthi Kivuva, Mehdi Knidiri, Komi Komi Koukoura, Eleojo Roseline Kwasi, Kim Labuschagne, Antoine Lusala Mafwila, Isabel Mensah, Uzoma Modebelu, Prudent Mokgokong, Morad M. Mokhtar, Sadik Muzemil, Helen Nigussie, Valentine Otang Ntui, Joel Ogwang, Nicholas Abraham Olivier, Olanrewaju Olufowobi, Taiwo Crossby Omotoriogun, Onikepe Folarin, Philomena Eromon, Jeremiah Orina, Faissal Ouardi, Tracy Parish, Mercy Peter, Jacques Potgieter, Fouzia Radouani, Madeleine Ramantswana, Shaimaa Roshdy Abdullah Reda, Samson Pandam Salifu, Sarah Bingaman Schwartz, Ntji Shabangu, Abdoallah Sharaf, Iyeopu Minakiri Siminialayi, Rae Marvin Smith, Hiroaki Taniguchi, Preye Maureen Tari-Ukuta, Kassahun Tesfaye, Fatim Zohra Tmimi, Libert Brice Tonfack, Ogbuagu Ugorji Udensi, Victoria Wavinya Wambua, Sammy Wambua, Kennedy Were, Timipanipiri ThankGod Wood, Bret Mark Wurdeman, Yedomon Ange Bovys Zoclanclounon, Andrews Frimpong Adu, Sotonye Leslie Gillis-Harry, Nicholas Kwasi-Do Ohene Opoku, Thendo Stanley Tshilate, Siyeofori Dede, Soala Obie Minimah, Yves Hermandez Tchiechoua, Andreas Gisel, Chadlia Hamdi, Tshepo Mafokwane, Blessing Adanta Odogwu, Gift Nwachukwu, Zahra Mungloo-Dilmohamud, Faten Ghodhbane-Gtari, Chinagorom Ibeachu, Renate Dorothea Zipfel, Wenceslaus C. Madu, Johnpaul Chukwudi Okorocha, Tracy Masebe, Kilsi Borgbara, Wynand Goosen, Suereta Fortuin, Kristien Nel Van Zyl, Ongeziwe Mbhele, Anise Happi, Christian Happi, Ntanganedzeni Mapholi, Julian Onyewuonyeoma Osuji, Anne WT Muigai, ThankGod Echezona Ebenezer, Bouabid Badaoui

“…Abstract The African BioGenome Project (AfricaBP) is a Pan-African initiative aimed at improving food systems and biodiversity conservation through genomics while ensuring equitable data sharing and benefits. The Open Institute is the knowledge exchange platform of the AfricaBP, which aims to bridge local knowledge gaps in biodiversity genomics and bioinformatics and enable infrastructural developments. …”
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Nomogram construction for overall survival in breast angiosarcoma based on clinicopathological features: a population-based cohort study by Peikai Ding, Luxiao Zhang, Shengbin Pei, Zheng Qu, Xiangyi Kong, Zhongzhao Wang, Jing Wang, Yi Fang

“…This study aimed to develop a nomogram to predict 3- and 5-year overall survival (OS) for BAS patients using key clinicopathological factors. Methods Data from 450 BAS patients diagnosed between 2000 and 2021 were extracted from SEER database. …”
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Effect of Er:YAG laser bone bed milling, with or without photobiomodulation, on the bone repair process of additive manufacturing implants in rats by Fernando Costa Neto, Isadora Breseghello, Laura Vidoto Paludetto, Sabrina Cruz Tfaile Frasnelli, Fábio Roberto de Souza Batista, Alberto Blay, Armando Boni, Fernando Costa Júnior, Roberta Okamoto

“…Reverse torque testing and real-time PCR (RT-PCR) analysis were conducted to evaluate the expression of osteogenic markers, including ALP, IBSP, OCN, and RUNX2. Data were analyzed using the Shapiro-Wilk test, followed by one-way ANOVA and Tukey's post hoc test, where applicable, with a significance level of p ≤ 0.05. …”
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Core prescription pattern of Chinese herbal medicine for depressive disorders in Taiwan: A nationwide population-based study by Diem Ngoc Hong Tran, I-Hsuan Hwang, Fun-Jou Chen, Yuan-Pu Tseng, Ching-Mao Chang, Shih-Jen Tsai, Jen-Lin Yang, Ta-Peng Wu, Chung-Hua Hsu, Fang-Pey Chen, Yen-Ying Kung

“…The collected data was analyzed to explore the patterns of herbal products. …”
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Unveiling large-scale velocity characteristics of rock glaciers in the Tibet-Pamir-Karakoram region using InSAR by Zhangyu Sun, Lin Liu, Chengyan Fan, Yan Hu, Francesca Baldacchino, Atanu Bhattacharya, Ella Wood, Tobias Bolch

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Insights From a User Experience‐Focused Virtual Study on the Feasibility and Challenges of Decentralized Clinical Trials by Yue Ma, Le Li, Gaili Gao, Huan Zhou, Jianmiao Yang, Jiao Zheng, Li Zheng, Lu Zhang, Min Jiang, Pu Li, Wenjing Zhou, Xia Chen, Ying Wang, Weiyi Zheng, Yan Zhang

“…Standard procedures were developed for each DCT element, addressing issues like identity verification and data privacy based on user perspectives. This study provided insights on implementing DCTs in China, identifying areas that need optimization to meet local regulatory and stakeholders' requirements. …”
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Hypoxia alters the response of ovarian cancer cells to the mitomycin C drug by Aleksandra Gawrylak, Aleksandra Gawrylak, Klaudia Brodaczewska, Roksana Iwanicka-Nowicka, Roksana Iwanicka-Nowicka, Marta Koblowska, Marta Koblowska, Agnieszka Synowiec, Lubomir Bodnar, Lubomir Bodnar, Cezary Szczylik, Bogdan Lesyng, Rafał Stec, Claudine Kieda, Claudine Kieda

“…Oxygen availability is critical for cell reactions; thus, the lack of consideration of hypoxia as the main regulator of the tumor microenvironment (TME) leads to misinterpreted data with consequences for translational applications. …”
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A targetable antioxidant defense mechanism to EZH2 inhibitors enhances tumor cell vulnerability to ferroptosis by Marta C. Nocito, Constanze Hantel, Antonio M. Lerario, Fabrizio Mastrorocco, Luca De Martino, Clara Musicco, Ida D. Perrotta, Mariafrancesca Scalise, Cesare Indiveri, Sergio Giannattasio, Pierre Val, Marilena Lanzino, Vincenzo Pezzi, Ivan Casaburi, Rosa Sirianni

“…Transcript changes correlated with metabolic data, which suggested the effects of EZH2i on ferroptosis. …”
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Novel Deep Learning Model for Glaucoma Detection Using Fusion of Fundus and Optical Coherence Tomography Images by Saad Islam, Ravinesh C. Deo, Prabal Datta Barua, Jeffrey Soar, U. Rajendra Acharya

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Machine learning reveals CAT gene as a novel potential diagnostic and prognostic biomarker in non-small cell lung cancer by Yi Tian, Wen-ya Zhao, Yi-ru Liu, Wen-wen Song, Qiao-xin Lin, Yan-na Gong, Yi-ting Deng, Dian-na Gu, Ling Tian

“…Herein, we would apply machine learning methods to specifically analyze the issue of biomarker applicability across different age groups in NSCLC. Methods Studies have shown a higher incidence of NSCLC in people over 40 years of age, and due to the limitations of data set, studies of individuals under 40 years of age were not included in this study. …”
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U-Net-based VGG19 model for improved facial expression recognition by Xiaohu ZHAO, Jingyi ZHANG, Mingzhi JIAO, Lixun XIE, Lanfei WANG, Weiqing SUN, Di ZHANG

“…Future work will explore the adaptability of the model to other datasets and additional optimization techniques, aiming to further enhance its performance and expand its applicability across diverse use cases.…”
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Development and evaluation of an ovarian hormone profile classification tool for female athletes: step one of a two-step process to determine ovarian hormone profiles by Alan McCall, Stuart M Phillips, Kirsty J Elliott-Sale, Rachel Harris, Richard J Burden, Georgina K Stebbings, Alysha C D'Souza, Clare Minahan, Thomas Dos’Santos, Tessa R Flood, Laurence P Birdsey, Nigel T Cable, Emma Clausen, Adam Field, Kelly L McNulty, Niamh Ní Chéilleachair, Ciaran O'Catháin, Glenn Sherwin, Bernadette C Taim, Derrick W Van Every, Joanna Więckowska

“…It incorporates self-reported data and guides subsequent verification methods. …”
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Machine learning for detection of diffusion abnormalities-related respiratory changes among normal, overweight, and obese individuals based on BMI and pulmonary ventilation paramet... by Xin-Yue Song, Xin-Peng Xie, Wen-Jing Xu, Yu-Jia Cao, Bin-Miao Liang

“…We evaluated the effectiveness of various supervised ML algorithms and identified the optimal configurations for these applications. Methods We conducted a retrospective analysis of data from 440 individuals who underwent pulmonary function tests between January 1, 2021, and April 1, 2024. …”
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